Jesse Alt

4.5k citations

73 papers · 3.3k · 1 hit paper · h-index 27

Impact in

Cancer Research top 2%
- Cancer, Hypoxia, and Metabolism
Biological Psychiatry top 5%

Papers in

Cellular and Molecular Neuroscience 17
- Neuroscience and Neuropharmacology Research 9
- Neuropeptides and Animal Physiology 8
Biochemistry 10
- Amino Acid Enzymes and Metabolism 10

Co-authors: Barbara Stauch Slusher (63 shared papers)Rana Rais (50 shared papers)Camilo J. Rojas (29 shared papers)Margaret M. McCarthy (3 shared papers)Ajit G. Thomas (22 shared papers)Marigo J. Stathis (7 shared papers)Jonathan D. Powell (6 shared papers)Eva Prchalová (7 shared papers)
Journals: Journal of Medicinal Chemistry (12 papers)Bioorganic & Medicinal Chemistry Letters (3 papers)Molecular Cancer Therapeutics (2 papers)The FASEB Journal (2 papers)European Journal of Medicinal Chemistry (2 papers)
Partner nations: United States Czechia Poland

In The Last Decade

Jesse Alt

71 papers receiving 3.2k citations

Jesse Alt's Hit Papers

align trajectories log scale

Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion 2019 · 891 citations

What are hit papers?

Paper score: A paper's citations measured against the top-1% bar of its own field and year: the square root of citations ÷ bar, so 1 means right at the bar and 2 means four times its citations. The bar blends the citation counts that enter the top 1% of the paper's subfields in its year (weighted 89.5%), of those subfields over all years (0.5%) and of its year across all fields (10%); a subfield and year with fewer than 400 papers takes its year's bar. Papers from 2026 are not scored yet: in an unfinished year, when a paper appeared matters more than how it is cited.

Hit paper: A paper cited at least 1.5× the top-1% bar of its field and year: a paper score of at least √1.5.

2019 Science

Peers

Countries citing papers authored by Jesse Alt

Since Specialization

Citations

This map shows the geographic impact of Jesse Alt's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jesse Alt with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jesse Alt more than expected).

Fields of papers citing papers by Jesse Alt

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jesse Alt. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jesse Alt. The network helps show where Jesse Alt may publish in the future.

Co-authors

The 25 scholars most cited alongside Jesse Alt, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Jesse Alt Line = papers co-authored together Jesse Alt links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 73 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion Science ·Robert D. Leone, Liang Zhao, Judson M. Englert, Im-Meng Sun, Min Hee Oh, Im‐Hong Sun, Matthew L. Arwood, Ian A. Bettencourt, Chirag H. Patel, Jiayu Wen, Ada J Tam, Richard L. Blosser, Eva Prchalová, Jesse Alt, Rana Rais, Barbara Stauch Slusher, Jonathan D. Powell Hit paper breakdown →	2019	891
2	Palonosetron Exhibits Unique Molecular Interactions with the 5-HT3 Receptor Anesthesia & Analgesia ·Camilo J. Rojas, Marigo J. Stathis, Ajit Thomas, Edward B. Massuda, Jesse Alt, Jie Zhang, E. B. Rubenstein, Silvia Sebastiani, Sergio Cantoreggi, Solomon H. Snyder, Barbara Stauch Slusher	2008	208
3	Brain Estradiol Content in Newborn Rats: Sex Differences, Regional Heterogeneity, and Possible de Novo Synthesis by the Female Telencephalon Endocrinology ·Stuart K. Amateau, Jesse Alt, Carolyn L. Stamps, Margaret M. McCarthy	2004	202
4	Palonosetron triggers 5-HT3 receptor internalization and causes prolonged inhibition of receptor function European Journal of Pharmacology ·Camilo J. Rojas, Ajit G. Thomas, Jesse Alt, Marigo J. Stathis, Jie Zhang, Edward B. Rubenstein, Silvia Sebastiani, Sergio Cantoreggi, Barbara Stauch Slusher	2009	171
5	Design, Synthesis, and Pharmacological Evaluation of Bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl Sulfide 3 (BPTES) Analogs as Glutaminase Inhibitors Journal of Medicinal Chemistry ·Krupa H. Shukla, Dana V. Ferraris, Ajit G. Thomas, Marigo J. Stathis, Bridget R. Duvall, Greg Delahanty, Jesse Alt, Rana Rais, Camilo J. Rojas, Ping Gao, (unknown), Chi V. Dang, Barbara Stauch Slusher, Takashi Tsukamoto	2012	163
6	Discovery of 6-Diazo-5-oxo- l -norleucine (DON) Prodrugs with Enhanced CSF Delivery in Monkeys: A Potential Treatment for Glioblastoma Journal of Medicinal Chemistry ·Rana Rais, Andrej Jančařík, Lukáš Tenora, Michael T. Nedelcovych, Jesse Alt, Judson M. Englert, Camilo Rojas, Anne T. Le, Amira Elgogary, Jessica Tan, Lenka Monincová, Kelly A. Metcalf Pate, Robert N. Adams, Dana V. Ferraris, Jonathan D. Powell, Pavel Majer, Barbara Stauch Slusher	2016	115
7	The Antiemetic 5-HT3 Receptor Antagonist Palonosetron Inhibits Substance P-Mediated Responses In Vitro and In Vivo Journal of Pharmacology and Experimental Therapeutics ·Camilo J. Rojas, Ying Li, Jie Zhang, Marigo J. Stathis, Jesse Alt, Ajit G. Thomas, Sergio Cantoreggi, Silvia Sebastiani, Claudio Pietra, Barbara Stauch Slusher	2010	115
8	Discovery of DRP-104, a tumor-targeted metabolic inhibitor prodrug Science Advances ·Rana Rais, Kathryn M. Lemberg, Lukáš Tenora, Matthew L. Arwood, Arindom Pal, Jesse Alt, Ying Wu, Jenny Lam, Joanna Marie H. Aguilar, Liang Zhao, Diane E. Peters, Carolyn Tallon, Rajeev Pandey, Ajit G. Thomas, Ranjeet Prasad Dash, Tanguy Y. Seiwert, Pavel Majer, Robert D. Leone, Jonathan D. Powell, Barbara Stauch Slusher	2022	92
9	The Diversity of Chemoprotective Glucosinolates in Moringaceae (Moringa spp.) Scientific Reports ·Jed W. Fahey, Mark E. Olson, Katherine K. Stephenson, Kristina L. Wade, Gwen Chodur, David Odee, Wasif Nouman, Michael Anthony Massiah, Jesse Alt, Patricia A. Egner, Walter C. Hubbard	2018	71
10	Inhibition of Glutamate Carboxypeptidase II (GCPII) activity as a treatment for cognitive impairment in multiple sclerosis Proceedings of the National Academy of Sciences ·Kristen A. Rahn, Crystal C. Watkins, Jesse Alt, Rana Rais, Marigo J. Stathis, Inna V. Grishkan, Ciprian M. Crainiceau, Martin G. Pomper, Camilo J. Rojas, Mikhail V. Pletnikov, Peter A. Calabresi, Jason Brandt, Peter B. Barker, Barbara Stauch Slusher, Adam Ian Kaplin	2012	65
11	A novel model for prenatal brain damage Experimental Neurology ·Joseph L. Nuñez, Jesse Alt, Margaret M. McCarthy	2003	65
12	N-(Pivaloyloxy)alkoxy-carbonyl Prodrugs of the Glutamine Antagonist 6-Diazo-5-oxo- l -norleucine (DON) as a Potential Treatment for HIV Associated Neurocognitive Disorders Journal of Medicinal Chemistry ·Michael T. Nedelcovych, Lukáš Tenora, Boe-Hyun Kim, Jennifer Kelschenbach, Wei Chao, Eran Hadas, Andrej Jančařík, Eva Prchalová, Sarah C. Zimmermann, Ranjeet Prasad Dash, Alexandra J. Gadiano, Caroline K. Garrett, Georg J. Furtmüller, Byoungchol Oh, Gerald Brandacher, Jesse Alt, Pavel Majer, David J. Volsky, Rana Rais, Barbara Stauch Slusher	2017	58
13	Prostate-specific membrane antigen (PSMA)-mediated laminin proteolysis generates a pro-angiogenic peptide Angiogenesis ·Rebecca E. Conway, Camilo J. Rojas, Jesse Alt, Zora Nováková, Spencer M. Richardson, Tori C. Rodrick, Julio L. Fuentes, Noah Hunter Richardson, Jonathan Attalla, Samantha Stewart, Beshoy Fahmy, Cyril Bařinka, Mallika Ghosh, Linda Hillstrom Shapiro, Barbara Stauch Slusher	2016	57
14	Orally bioavailable glutamine antagonist prodrug JHU-083 penetrates mouse brain and suppresses the growth of MYC-driven medulloblastoma Translational Oncology ·Allison Rose Hanaford, Jesse Alt, Rana Rais, Sabrina Z. Wang, Harpreet Kaur, Daniel L.J. Thorek, Charles G. Eberhart, Barbara Stauch Slusher, Allison M. Martin, Eric H. Raabe	2019	56
15	Tumor-Targeted Delivery of 6-Diazo-5-oxo- l -norleucine (DON) Using Substituted Acetylated Lysine Prodrugs Journal of Medicinal Chemistry ·Lukáš Tenora, Jesse Alt, Ranjeet Prasad Dash, Alexandra J. Gadiano, Kateřina Novotná, Vijayabhaskar Veeravalli, Jenny Lam, Quinn R. Kirkpatrick, Kathryn M. Lemberg, Pavel Majer, Rana Rais, Barbara Stauch Slusher	2019	51
16	Design, Synthesis, and Pharmacological Evaluation of Fluorinated Tetrahydrouridine Derivatives as Inhibitors of Cytidine Deaminase Journal of Medicinal Chemistry ·Dana V. Ferraris, Bridget R. Duvall, Greg Delahanty, Bipin Mistry, Jesse Alt, Camilo J. Rojas, Christopher Rowbottom, Kristen M. Sanders, Edgar L. Schuck, Kuan-Chun Huang, Sanjeev Redkar, Barbara Slusher, Takashi Tsukamoto	2014	47
17	JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents depression-associated behaviors induced by chronic social defeat stress Neuropsychopharmacology ·Xiaolei Zhu, Michael T. Nedelcovych, Ajit G. Thomas, Yuto Hasegawa, Aisa Moreno-Megui, Wade Coomer, Varun Vohra, Atsushi Saito, Gabriel Pérez‐Lucas, Ying Wu, Jesse Alt, Eva Prchalová, Lukáš Tenora, Pavel Majer, Rana Rais, Camilo J. Rojas, Barbara Stauch Slusher, Atsushi Kamiya	2018	46
18	A new model for prenatal brain damage Experimental Neurology ·Joseph L. Nuñez, Jesse Alt, Margaret M. McCarthy	2003	44
19	6-Hydroxy-1,2,4-triazine-3,5(2 H ,4 H )-dione Derivatives as Novel d -Amino Acid Oxidase Inhibitors Journal of Medicinal Chemistry ·Niyada Hin, Bridget R. Duvall, Dana V. Ferraris, Jesse Alt, Ajit G. Thomas, Rana Rais, Camilo J. Rojas, Ying Wu, Krystyna M. Wozniak, Barbara Stauch Slusher, Takashi Tsukamoto	2015	44
20	Inhibition of xc- transporter-mediated cystine uptake by sulfasalazine analogs Bioorganic & Medicinal Chemistry Letters ·Krupa H. Shukla, Ajit G. Thomas, Dana V. Ferraris, Niyada Hin, Rita Sattler, Jesse Alt, Camilo J. Rojas, Barbara Stauch Slusher, Takashi Tsukamoto	2011	38

About Jesse Alt

Jesse Alt is a scholar working on Cellular and Molecular Neuroscience, Biochemistry, Cancer Research, Neurology and Molecular Biology, having authored 73 papers that have together received 3.3k indexed citations. Recurring topics across this work include Cancer, Hypoxia, and Metabolism (10 papers), Amino Acid Enzymes and Metabolism (10 papers), Neuroscience and Neuropharmacology Research (9 papers), Neuropeptides and Animal Physiology (8 papers), Neuroinflammation and Neurodegeneration Mechanisms (7 papers), Biochemical and Molecular Research (5 papers), Epigenetics and DNA Methylation (5 papers) and HIV Research and Treatment (4 papers). The work is most often cited by research in Cancer Research (882 citations), Biological Psychiatry (93 citations), Biochemistry (242 citations), Immunology (527 citations) and Behavioral Neuroscience (85 citations). Jesse Alt has collaborated with scholars based in United States, Czechia and Poland. Frequent co-authors include Barbara Stauch Slusher, Rana Rais, Camilo J. Rojas, Margaret M. McCarthy, Ajit G. Thomas, Marigo J. Stathis, Jonathan D. Powell, Eva Prchalová, Liang Zhao and Robert D. Leone. Their work appears in journals such as Journal of Medicinal Chemistry, Bioorganic & Medicinal Chemistry Letters, Molecular Cancer Therapeutics, The FASEB Journal and European Journal of Medicinal Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Jesse Alt

Jesse Alt's Hit Papers

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Fields of papers citing papers by Jesse Alt

All Works

About Jesse Alt

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