James Darnell

88.1k citations
452 papers · 73.7k · 32 hit papers · h-index 133

Impact in

  • Oncology top 0.01%
    • Cytokine Signaling Pathways and Interactions
  • Immunology top 0.01%
    • interferon and immune responses
    • Immune Cell Function and Interaction

Papers in

    • RNA Research and Splicing 97
    • RNA and protein synthesis mechanisms 88
    • RNA modifications and cancer 49
    • Viral Infectious Diseases and Gene Expression in Insects 35
    • Cytokine Signaling Pathways and Interactions 98

James Darnell

444 papers receiving 70.2k citations

James Darnell's Hit Papers

The JAK-STAT pathway at 30: Much learned, much more to do 2022 · 429 citations
4290+10+20Years since publication10002.0k3.0k

Peers

James Darnell
Comparison fields: 5 of 176
  • Oncology 29.6k
  • Immunology 21.7k
  • Molecular Biology 39.3k
  • Cancer Research 7.9k
  • Pharmacology 3.3k
Replace Ira Pastan with:
Ira Pastan United States
George R. Stark United States
Michael B. Sporn United States
Joseph Schlessinger United States
Robert D. Schreiber United States
John C. Reed United States
Tak W. Mak Canada
Tony Hunter United States
Shigekazu Nagata Japan
Stanley J. Korsmeyer United States
James Darnell relative to Ira Pastan United States Ira Pastan's profile →
Citations per field
00.5×1.5×2.3×
Ira Pastan · 1×
Citations per year

Countries citing papers authored by James Darnell

Since Specialization
Citations

This map shows the geographic impact of James Darnell's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by James Darnell with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites James Darnell more than expected).

Fields of papers citing papers by James Darnell

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by James Darnell. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by James Darnell. The network helps show where James Darnell may publish in the future.

Co-authors

The 25 scholars most cited alongside James Darnell, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with James Darnell Line = papers co-authored together James Darnell links everyone, so they are left out of the graph.

All Works

20 of 20 papers shown

Showing the 20 most-cited of 452 papers — load more, or switch the sort, to bring in the rest.

#Work
1
Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins
Hit paper breakdown →
19945118
2
STATs and Gene Regulation
Hit paper breakdown →
19973384
3
STATs: transcriptional control and biological impact
Hit paper breakdown →
20022603
4
Stat3 as an Oncogene
Hit paper breakdown →
19992454
5
Stat3: a STAT Family Member Activated by Tyrosine Phosphorylation in Response to Epidermal Growth Factor and Interleukin-6
Hit paper breakdown →
19941796
6
Maximal activation of transcription by statl and stat3 requires both tyrosine and serine phosphorylation
Hit paper breakdown →
19951733
7
TRANSCRIPTIONAL RESPONSES TO POLYPEPTIDE LIGANDS: The JAK-STAT Pathway
Hit paper breakdown →
19951616
8
The JAK-STAT Pathway at Twenty
Hit paper breakdown →
20121191
9
The role of STATs in transcriptional control and their impact on cellular function
Hit paper breakdown →
20001038
10
Transcription factors as targets for cancer therapy
Hit paper breakdown →
2002950
11
Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily.
Hit paper breakdown →
1990934
12
Sedimentation characteristics of rapidly labelled RNA from HeLa cells
Hit paper breakdown →
1962926
13
Leptin activation of Stat3 in the hypothalamus of wild–type and ob/ob mice but not db/db mice
Hit paper breakdown →
1996923
14
Choice of STATs and Other Substrates Specified by Modular Tyrosine-Based Motifs in Cytokine Receptors
Hit paper breakdown →
1995843
15
Interferon-Dependent Tyrosine Phosphorylation of a Latent Cytoplasmic Transcription Factor
Hit paper breakdown →
1992776
16
Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions
Hit paper breakdown →
1994710
17
A Single Phosphotyrosine Residue of Stat91 Required for Gene Activation by Interferon-γ
Hit paper breakdown →
1993708
18
Activation of Transcription by IFN-γ: Tyrosine Phosphorylation of a 91-kD DNA Binding Protein
Hit paper breakdown →
1992694
19
The winged-helix transcription factor HNF-3β is required for notochord development in the mouse embryo
Hit paper breakdown →
1994674
20
A majority of m6A residues are in the last exons, allowing the potential for 3′ UTR regulation
Hit paper breakdown →
2015657

About James Darnell

James Darnell is a scholar working on Molecular Biology, Oncology, Genetics, Immunology and Cardiology and Cardiovascular Medicine, having authored 452 papers that have together received 73.7k indexed citations. Recurring topics across this work include Cytokine Signaling Pathways and Interactions (98 papers), RNA Research and Splicing (97 papers), RNA and protein synthesis mechanisms (88 papers), Virus-based gene therapy research (50 papers), RNA modifications and cancer (49 papers), interferon and immune responses (48 papers), Viral Infectious Diseases and Gene Expression in Insects (35 papers) and Viral Infections and Immunology Research (34 papers). The work is most often cited by research in Oncology (29.6k citations), Immunology (21.7k citations), Molecular Biology (39.3k citations), Cancer Research (7.9k citations) and Pharmacology (3.3k citations). James Darnell has collaborated with scholars based in United States, United Kingdom and Germany. Frequent co-authors include George R. Stark, David E. Levy, Zhong Zhong, Zilong Wen, Jacqueline Bromberg, Christian Schindler, Ke Shuai, Curt M. Horvath, Vincent R. Prezioso and George R. Stark. Their work appears in journals such as Molecular and Cellular Biology, Proceedings of the National Academy of Sciences, Journal of Molecular Biology, Cell and Science.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact