J.A. Christopher

2.4k citations

62 papers · 1.9k · h-index 22

Impact in

Cellular and Molecular Neuroscience top 5%
- Neuropeptides and Animal Physiology
- Neuroscience and Neuropharmacology Research
Pharmaceutical Science top 5%

Papers in

Molecular Biology 23
- Receptor Mechanisms and Signaling 9
- Chemical Synthesis and Analysis 8
Organic Chemistry 19
- Synthesis and Biological Evaluation 9
- Synthesis and Reactivity of Heterocycles 7

Co-authors: Miles Congreve (10 shared papers)A.S. Dore (7 shared papers)Fiona H. Marshall (8 shared papers)James C. Errey (6 shared papers)Kenneth G. Rice (1 shared paper)K.A. Bennett (5 shared papers)Benjamin G. Tehan (7 shared papers)David D. Miller (16 shared papers)
Journals: Journal of Medicinal Chemistry (8 papers)Tetrahedron (7 papers)Bioorganic & Medicinal Chemistry Letters (7 papers)Current Topics in Medicinal Chemistry (3 papers)Beilstein Journal of Organic Chemistry (2 papers)
Partner nations: United Kingdom United States Netherlands

In The Last Decade

J.A. Christopher

62 papers receiving 1.8k citations

Peers

Countries citing papers authored by J.A. Christopher

Since Specialization

Citations

This map shows the geographic impact of J.A. Christopher's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by J.A. Christopher with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites J.A. Christopher more than expected).

Fields of papers citing papers by J.A. Christopher

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by J.A. Christopher. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by J.A. Christopher. The network helps show where J.A. Christopher may publish in the future.

Co-authors

The 25 scholars most cited alongside J.A. Christopher, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with J.A. Christopher Line = papers co-authored together J.A. Christopher links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 62 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Intracellular allosteric antagonism of the CCR9 receptor Nature ·Christine Oswald, Mathieu Rappas, James Kean, A.S. Dore, James C. Errey, K.A. Bennett, Francesca Deflorian, J.A. Christopher, Ali Jazayeri, Jonathan S. Mason, Miles Congreve, Roger Cooke, Fiona H. Marshall	2016	204
2	Perfectionism, stress, and social (dis)connection: A short-term study of hopelessness, depression, and academic adjustment among honors students. Journal of Counseling Psychology ·Kenneth G. Rice, Brooke A. Leever, J.A. Christopher, J. Diane Porter	2006	152
3	Fragment and Structure-Based Drug Discovery for a Class C GPCR: Discovery of the mGlu ₅ Negative Allosteric Modulator HTL14242 (3-Chloro-5-[6-(5-fluoropyridin-2-yl)pyrimidin-4-yl]benzonitrile) Journal of Medicinal Chemistry ·J.A. Christopher, Sarah J. Aves, K.A. Bennett, A.S. Dore, James C. Errey, Ali Jazayeri, Fiona H. Marshall, Krzysztof Okrasa, María J. Serrano‐Vega, Benjamin G. Tehan, Giselle R. Wiggin, Miles Congreve	2015	133
4	Biophysical Fragment Screening of the β ₁ -Adrenergic Receptor: Identification of High Affinity Arylpiperazine Leads Using Structure-Based Drug Design Journal of Medicinal Chemistry ·J.A. Christopher, Jason Brown, A.S. Dore, James C. Errey, Markus Koglin, Fiona H. Marshall, David G. Myszka, Rebecca L. Rich, Christopher G. Tate, Benjamin G. Tehan, Tony Warne, Miles Congreve	2013	132
5	Sexual precocity: sex incidence and aetiology. Archives of Disease in Childhood ·Nicola Bridges, J.A. Christopher, Peter C. Hindmarsh, C. G. D. Brook	1994	118
6	N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)amides as potent, selective, inhibitors of JNK2 and JNK3 Bioorganic & Medicinal Chemistry Letters ·Richard Angell, Francis Atkinson, Murray J. B. Brown, Tsu Tshen Chuang, J.A. Christopher, Maria A. Cichy-Knight, Allison K. Dunn, Kendra E. Hightower, Susanna Malkakorpi, James Musgrave, Margarete Neu, Paul Rowland, Robyn Shea, Jeffery L. Smith, D.O. Somers, Sonia Thomas, Gladstone Thompson, Ruolan Wang	2006	73
7	Structure-Based Optimization Strategies for G Protein-Coupled Receptor (GPCR) Allosteric Modulators: A Case Study from Analyses of New Metabotropic Glutamate Receptor 5 (mGlu ₅ ) X-ray Structures Journal of Medicinal Chemistry ·J.A. Christopher, Zoltán Orgován, Miles Congreve, A.S. Dore, James C. Errey, Fiona H. Marshall, Jonathan S. Mason, Krzysztof Okrasa, Prakash Rucktooa, María J. Serrano‐Vega, György G. Ferenczy, György M. Keserű	2018	70
8	Cognitive, behavioral, and family factors in the differentiation of depressive and anxiety disorders during childhood. Journal of Consulting and Clinical Psychology ·Kevin D. Stark, Laura L. Humphrey, Jeff Laurent, Ronnie Livingston, J.A. Christopher	1993	65
9	Structure‐Based and Fragment‐Based GPCR Drug Discovery ChemMedChem ·Stephen P. Andrews, Giles A. Brown, J.A. Christopher	2013	60
10	Comparison of Orexin 1 and Orexin 2 Ligand Binding Modes Using X-ray Crystallography and Computational Analysis Journal of Medicinal Chemistry ·Mathieu Rappas, A. Ali, K.A. Bennett, Jason Brown, S.J. Bucknell, Miles Congreve, Roger Cooke, G. Cseke, Chris de Graaf, A.S. Dore, James C. Errey, Ali Jazayeri, Fiona H. Marshall, Jonathan Mason, Richard F. Mould, Jayesh C. Patel, Benjamin G. Tehan, Malcolm Weir, J.A. Christopher	2019	57
11	Selectivity of Kinase Inhibitor Fragments Journal of Medicinal Chemistry ·Paul Bamborough, Murray J. B. Brown, J.A. Christopher, Chun‐wa Chung, Geoff Mellor	2011	56
12	The discovery of 2-amino-3,5-diarylbenzamide inhibitors of IKK-α and IKK-β kinases Bioorganic & Medicinal Chemistry Letters ·J.A. Christopher, Barbara G. Avitabile, Paul Bamborough, Aurélie C. Champigny, Geoffrey J. Cutler, Susan L. Dyos, Ken Grace, Jeffrey K. Kerns, Jeremy Kitson, Geoffrey W. Mellor, J. V. Morey, Mary A. Morse, Carolyn F. O’Malley, Champa Patel, Nicholas Probst, William L. Rumsey, Clive A. Smith, Michael J. Wilson	2007	55
13	5-(1H-Benzimidazol-1-yl)-3-alkoxy-2-thiophenecarbonitriles as potent, selective, inhibitors of IKK-ε kinase Bioorganic & Medicinal Chemistry Letters ·Paul Bamborough, J.A. Christopher, Geoffrey J. Cutler, Marion C. Dickson, Geoffrey W. Mellor, J. V. Morey, Champa Patel, Lisa M. Shewchuk	2006	46
14	Recent Developments in Therapeutic Peptides for the Glucagon-like Peptide 1 and 2 Receptors Journal of Medicinal Chemistry ·Rie Suzuki, Giles A. Brown, J.A. Christopher, Conor C. G. Scully, Miles Congreve	2019	46
15	Oocyte maturation in starfish is mediated by the βγ-subunit complex of a G-protein The Journal of Cell Biology ·Laurinda A. Jaffe, J.A. Christopher, Rehwa H. Lee, Yee-Kin Ho, Teresa L. Z. Jonesll	1993	44
16	Dipyrido[1,2-a;3′,4′-d]imidazole systems Tetrahedron ·Matthew W. Cartwright, L. Convery, T. Kraynck, Graham Sandford, Dmitrii S. Yufit, Judith A. K. Howard, J.A. Christopher, David D. Miller	2009	42
17	N-4-Pyrimidinyl-1H-indazol-4-amine inhibitors of Lck: Indazoles as phenol isosteres with improved pharmacokinetics Bioorganic & Medicinal Chemistry Letters ·Paul Bamborough, Richard Angell, Inder Bhamra, David Brown, James A. Bull, J.A. Christopher, (unknown), Lynsey Fazal, Ilaria Giordano, Lucy Hind, Vipulkumar K. Patel, Lisa E. Ranshaw, Martin Sims, Philip A. Skone, Kathryn J. Smith, Emma Vickerstaff, Melanie Washington	2007	41
18	1-Aryl-3,4-dihydroisoquinoline inhibitors of JNK3 Bioorganic & Medicinal Chemistry Letters ·J.A. Christopher, Francis Atkinson, B.D. Bax, Murray J. B. Brown, Aurélie C. Champigny, Tsu Tshen Chuang, Emma J. Jones, J. Mosley, James Musgrave	2009	31
19	Discovery of 6-Aryl-7-alkoxyisoquinoline Inhibitors of IκB Kinase-β (IKK-β) Journal of Medicinal Chemistry ·J.A. Christopher, Paul Bamborough, Catherine M. Alder, Amanda Campbell, Geoffrey J. Cutler, Kenneth Down, Ahmed M. Hamadi, Adrian M. Jolly, Jeffrey K. Kerns, Fiona S. Lucas, Geoffrey W. Mellor, David D. Miller, Mary A. Morse, Kiritkant D. Pancholi, William L. Rumsey, Yemisi Solanke, Rick Williamson	2009	30
20	Imidazopyridine and pyrimidinopyridine systems from perfluorinated pyridine derivatives Tetrahedron ·Matthew W. Cartwright, Graham Sandford, Jamaal Bousbaa, Dmitrii S. Yufit, Judith A. K. Howard, J.A. Christopher, David D. Miller	2007	29

About J.A. Christopher

J.A. Christopher is a scholar working on Molecular Biology, Organic Chemistry, Cellular and Molecular Neuroscience, Oncology and Cognitive Neuroscience, having authored 62 papers that have together received 1.9k indexed citations. Recurring topics across this work include Receptor Mechanisms and Signaling (9 papers), Synthesis and Biological Evaluation (9 papers), Chemical Synthesis and Analysis (8 papers), Synthesis and Reactivity of Heterocycles (7 papers), Cytokine Signaling Pathways and Interactions (7 papers), Neuropeptides and Animal Physiology (7 papers), Sleep and Wakefulness Research (6 papers) and NF-κB Signaling Pathways (5 papers). The work is most often cited by research in Cellular and Molecular Neuroscience (398 citations), Pharmaceutical Science (96 citations), Molecular Biology (938 citations), Organic Chemistry (388 citations) and Reproductive Medicine (101 citations). J.A. Christopher has collaborated with scholars based in United Kingdom, United States and Netherlands. Frequent co-authors include Miles Congreve, A.S. Dore, Fiona H. Marshall, James C. Errey, Kenneth G. Rice, K.A. Bennett, Benjamin G. Tehan, David D. Miller, Ali Jazayeri and Peter C. Hindmarsh. Their work appears in journals such as Journal of Medicinal Chemistry, Tetrahedron, Bioorganic & Medicinal Chemistry Letters, Current Topics in Medicinal Chemistry and Beilstein Journal of Organic Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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