Hiroshi Handa

26.2k citations
413 papers · 20.9k · 7 hit papers · h-index 72

Impact in

    • RNA Research and Splicing
    • Protein Degradation and Inhibitors
    • Genomics and Chromatin Dynamics
    • Ubiquitin and proteasome pathways
    • RNA and protein synthesis mechanisms
    • RNA modifications and cancer
  • Hematology top 0.2%
    • Multiple Myeloma Research and Treatments

Papers in

    • RNA Research and Splicing 49
    • Genomics and Chromatin Dynamics 37
    • Protein Degradation and Inhibitors 33
    • RNA Interference and Gene Delivery 31
    • Ubiquitin and proteasome pathways 30
    • Viral Infectious Diseases and Gene Expression in Insects 29
    • Virus-based gene therapy research 47

Hiroshi Handa

405 papers receiving 20.3k citations

Hiroshi Handa's Hit Papers

Structure of the human Cereblon–DDB1–lenalidomide complex reveals basis for responsiveness to thalidomide analogs 2014 · 385 citations
3850+9+18Years since publication50010001.5k

Peers

Hiroshi Handa
Comparison fields: 5 of 168
  • Molecular Biology 14.3k
  • Hematology 2.1k
  • Virology 530
  • Oncology 2.6k
  • Immunology 2.0k
Replace Robert Liddington with:
Robert Liddington United States
Isabelle Callebaut France
John M. Chirgwin United States
Elisabeth Kremmer Germany
Hendrik G. Stunnenberg Netherlands
Saadi Khochbin France
Toshio Kitamura Japan
David W. Speicher United States
Michael R. Green United States
Larry R. Pease United States
Hiroshi Handa relative to Robert Liddington United States Robert Liddington's profile →
Citations per field
00.5×2.9×
Robert Liddington · 1×
Citations per year

Countries citing papers authored by Hiroshi Handa

Since Specialization
Citations

This map shows the geographic impact of Hiroshi Handa's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hiroshi Handa with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hiroshi Handa more than expected).

Fields of papers citing papers by Hiroshi Handa

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hiroshi Handa. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hiroshi Handa. The network helps show where Hiroshi Handa may publish in the future.

Co-authors

The 25 scholars most cited alongside Hiroshi Handa, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Hiroshi Handa Line = papers co-authored together Hiroshi Handa links everyone, so they are left out of the graph.

All Works

20 of 20 papers shown

Showing the 20 most-cited of 413 papers — load more, or switch the sort, to bring in the rest.

#Work
1
Identification of a Primary Target of Thalidomide Teratogenicity
Hit paper breakdown →
20101600
2
NELF, a Multisubunit Complex Containing RD, Cooperates with DSIF to Repress RNA Polymerase II Elongation
Hit paper breakdown →
1999672
3
Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide
Hit paper breakdown →
2012623
4
DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs
Hit paper breakdown →
1998622
5
Redox Regulation of NF-κB Activation: Distinct Redox Regulation Between the Cytoplasm and the Nucleus
Hit paper breakdown →
2005501
6 1992484
7
Immunomodulatory agents lenalidomide and pomalidomide co‐stimulate T cells by inducing degradation of T cell repressors I karos and A iolos via modulation of the E 3 ubiquitin ligase complex CRL 4 CRBN
Hit paper breakdown →
2013472
8 1998390
9
Structure of the human Cereblon–DDB1–lenalidomide complex reveals basis for responsiveness to thalidomide analogs
Hit paper breakdown →
2014385
10 2006305
11 2003259
12 2000221
13 2003204
14 2002202
15 2007187
16 2002186
17 2003181
18 2005166
19 2001163
20 1995159

About Hiroshi Handa

Hiroshi Handa is a scholar working on Molecular Biology, Genetics, Immunology, Oncology and Biomedical Engineering, having authored 413 papers that have together received 20.9k indexed citations. Recurring topics across this work include RNA Research and Splicing (49 papers), Virus-based gene therapy research (47 papers), Genomics and Chromatin Dynamics (37 papers), Protein Degradation and Inhibitors (33 papers), RNA Interference and Gene Delivery (31 papers), Ubiquitin and proteasome pathways (30 papers), Characterization and Applications of Magnetic Nanoparticles (29 papers) and Viral Infectious Diseases and Gene Expression in Insects (29 papers). The work is most often cited by research in Molecular Biology (14.3k citations), Hematology (2.1k citations), Virology (530 citations), Oncology (2.6k citations) and Immunology (2.0k citations). Hiroshi Handa has collaborated with scholars based in Japan, United States and Nepal. Frequent co-authors include Yuki Yamaguchi, Takumi Ito, Tadashi Wada, Hideki Ando, Yasuaki Kabe, Takuro Wada, Toshihiko Ogura, Yoshimasa Imamura, Takayuki Suzuki and Hajime Watanabe. Their work appears in journals such as Journal of Biological Chemistry, Molecular and Cellular Biology, Genes to Cells, Biochemical and Biophysical Research Communications and Journal of Applied Physics.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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