Edwin J. Iwanowicz

1.6k citations

44 papers · 1.1k · h-index 20

Impact in

Organic Chemistry top 5%
- Synthesis and Biological Evaluation
- Click Chemistry and Applications
- Asymmetric Synthesis and Catalysis
- Synthesis and Catalytic Reactions
- Synthesis and Characterization of Heterocyclic Compounds
- Catalytic C–H Functionalization Methods
Physiology top 5%

Papers in

Molecular Biology 28
- Biochemical and Molecular Research 13
- Chemical Synthesis and Analysis 10
Organic Chemistry 16
- Synthesis and Biological Evaluation 4

Co-authors: James C. Lin (10 shared papers)Michael A. Poss (3 shared papers)R. H. Schlessinger (4 shared papers)Joel C. Barrish (13 shared papers)Zhengxiang Gu (1 shared paper)T. G. Murali Dhar (14 shared papers)James P. Springer (2 shared papers)Diane Hollenbaugh (13 shared papers)
Journals: Bioorganic & Medicinal Chemistry Letters (19 papers)Tetrahedron Letters (5 papers)Journal of Medicinal Chemistry (1 paper)Blood (1 paper)Structure (1 paper)
Partner nations: United States Germany Australia

In The Last Decade

Edwin J. Iwanowicz

43 papers receiving 1.0k citations

Peers

Countries citing papers authored by Edwin J. Iwanowicz

Since Specialization

Citations

This map shows the geographic impact of Edwin J. Iwanowicz's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Edwin J. Iwanowicz with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Edwin J. Iwanowicz more than expected).

Fields of papers citing papers by Edwin J. Iwanowicz

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Edwin J. Iwanowicz. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Edwin J. Iwanowicz. The network helps show where Edwin J. Iwanowicz may publish in the future.

Co-authors

The 25 scholars most cited alongside Edwin J. Iwanowicz, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Edwin J. Iwanowicz Line = papers co-authored together Edwin J. Iwanowicz links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 44 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Mitochondrial Protease ClpP is a Target for the Anticancer Compounds ONC201 and Related Analogues ACS Chemical Biology ·Paul R. Graves, Lucas J. Aponte‐Collazo, Emily M.J. Fennell, Adam C. Graves, Andrew Hale, Nedyalka Dicheva, Laura E. Herring, Thomas S.K. Gilbert, Michael P. East, Ian M. McDonald, Matthew R. Lockett, Hani Ashamalla, Nathaniel J. Moorman, Donald S. Karanewsky, Edwin J. Iwanowicz, Ekhson Holmuhamedov, Lee M. Graves	2019	140
2	A mild and efficient method for the preparation of guanidines Tetrahedron Letters ·Michael A. Poss, Edwin J. Iwanowicz, Joyce A. Reid, James C. Lin, Zhengxiang Gu	1992	114
3	Preparation ofN,N'-bis-tert-Butoxycarbonylthiourea Synthetic Communications ·Edwin J. Iwanowicz, Michael A. Poss, James C. Lin	1993	73
4	The synthesis of either (+) or (−) trans-2,5-dimethylpyrrolidine Tetrahedron Letters ·R. H. Schlessinger, Edwin J. Iwanowicz	1987	45
5	α-hydroxy- and α-ketoester functionalized thrombin inhibitors Bioorganic & Medicinal Chemistry Letters ·Edwin J. Iwanowicz, James C. Lin, Daniel G. Roberts, Inge M. Michel, Steven M. Seiler	1992	34
6	Potent ClpP agonists with anticancer properties bind with improved structural complementarity and alter the mitochondrial N-terminome Structure ·Mark Mabanglo, Keith S. Wong, Marim Barghash, Elisa Leung, Stephanie H. W. Chuang, Afshan Ardalan, Emily Majaesic, Cassandra J. Wong, Shen Zhang, Henk Lang, Donald S. Karanewsky, Andrew A. Iwanowicz, Lee M. Graves, Edwin J. Iwanowicz, Anne‐Claude Gingras, Walid A. Houry	2022	33
7	Reaction of quinoxalin-2-ones with TosMIC reagent: synthesis of imidazo[1,5-a]quinoxalin-4-ones Tetrahedron Letters ·Ping Chen, Joel C. Barrish, Edwin J. Iwanowicz, James C. Lin, Mark S. Bednarz, Bang‐Chi Chen	2001	33
8	An enantio- and erythro-selective lithium enolate derived from a vinylogous urethane: its application as a C4 synthon to the virginiamycin M2 problem The Journal of Organic Chemistry ·R. H. Schlessinger, Edwin J. Iwanowicz, James P. Springer	1986	32
9	3-Cyanoindole-based inhibitors of inosine monophosphate dehydrogenase: synthesis and initial structure–Activity relationships Bioorganic & Medicinal Chemistry Letters ·T. G. Murali Dhar, Zhongqi Shen, Henry H. Gu, Ping Chen, Derek Norris, Scott H. Watterson, Shelley K. Ballentine, Catherine Fleener, Katherine A. Rouleau, Joel C. Barrish, Robert M. Townsend, Diane Hollenbaugh, Edwin J. Iwanowicz	2003	31
10	Rapid synthesis of triazine inhibitors of inosine monophosphate dehydrogenase Bioorganic & Medicinal Chemistry Letters ·William J. Pitts, Junqing Guo, T. G. Murali Dhar, Zhongqi Shen, Henry H. Gu, Scott H. Watterson, Mark S. Bednarz, Bang‐Chi Chen, Joel C. Barrish, Donna A. Bassolino, Daniel L. Cheney, Catherine Fleener, Katherine A. Rouleau, Diane Hollenbaugh, Edwin J. Iwanowicz	2002	31
11	Highly diastereoselective alkylation reactions of vinylogous urethanes derived from simple tetronic acids Tetrahedron Letters ·R. H. Schlessinger, Edwin J. Iwanowicz, James P. Springer	1988	31
12	Novel indole-based inhibitors of IMPDH: introduction of hydrogen bond acceptors at indole C-3 Bioorganic & Medicinal Chemistry Letters ·Scott H. Watterson, T. G. Murali Dhar, Shelley K. Ballentine, Zhongqi Shen, Joel C. Barrish, Daniel L. Cheney, Catherine Fleener, Katherine A. Rouleau, Robert M. Townsend, Diane Hollenbaugh, Edwin J. Iwanowicz	2003	30
13	A Modified Approach to 2-(N-Aryl)-1,3-oxazoles: Application to the Synthesis of the IMPDH Inhibitor BMS-337197 and Analogues Organic Letters ·T. G. Murali Dhar, Junqing Guo, Zhongqi Shen, William J. Pitts, Henry H. Gu, Bang‐Chi Chen, (unknown), Mark S. Bednarz, Edwin J. Iwanowicz	2002	30
14	Structure of a Retro-binding Peptide Inhibitor Complexed with Human α-Thrombin Journal of Molecular Biology ·Lydia Taberno, ChiehYing Y. Chang, Shari L. Ohringer, Wan F. Lau, Edwin J. Iwanowicz, Wen-Ching Han, Tammy C. Wang, Steven M. Seiler, Daniel G. Roberts, John S. Sack	1995	29
15	Characterization of TR ‐107, a novel chemical activator of the human mitochondrial protease ClpP Pharmacology Research & Perspectives ·Emily M.J. Fennell, Lucas J. Aponte‐Collazo, Joshua D. Wynn, Kristina Drizyte‐Miller, Elisa Leung, Yoshimi Endo Greer, Paul R. Graves, Andrew A. Iwanowicz, Hani Ashamalla, Ekhson Holmuhamedov, Henk Lang, Donald S. Karanewsky, Channing J. Der, Walid A. Houry, Stanley Lipkowitz, Edwin J. Iwanowicz, Lee M. Graves	2022	28
16	Discovery and initial SAR of imidazoquinoxalines as inhibitors of the Src-family kinase p56Lck Bioorganic & Medicinal Chemistry Letters ·Ping Chen, Derek Norris, Edwin J. Iwanowicz, Steven H. Spergel, James C. Lin, Henry H. Gu, Zhongqi Shen, John Wityak, Tai-An Lin, Suhong Pang, H. Fex, Sidney Pitt, Ding Ren Shen, Arthur M. Doweyko, Donna A. Bassolino, Jacques Y. Roberge, Michael A. Poss, Bang‐Chi Chen, Gary L. Schieven, Joel C. Barrish	2002	28
17	Derivatives of 5-amidine indole as inhibitors of thrombin catalytic activity Bioorganic & Medicinal Chemistry Letters ·Edwin J. Iwanowicz, Wan F. Lau, James C. Lin, Daniel G. Roberts, Steven M. Seiler	1996	25
18	Novel inhibitors of IMPDH Bioorganic & Medicinal Chemistry Letters ·Scott H. Watterson, Marianne Carlsen, T. G. Murali Dhar, Zhongqi Shen, William J. Pitts, Junqing Guo, Henry H. Gu, Derek Norris, John S. Chorba, Ping Chen, Daniel L. Cheney, Mark R. Witmer, Catherine Fleener, Katherine A. Rouleau, Robert M. Townsend, Diane Hollenbaugh, Edwin J. Iwanowicz	2003	23
19	Mitochondrial Matrix Protease ClpP Agonists Inhibit Cancer Stem Cell Function in Breast Cancer Cells by Disrupting Mitochondrial Homeostasis Cancer Research Communications ·Yoshimi Endo Greer, Lídia Hernandez, Emily M.J. Fennell, Manjari Kundu, Donna Voeller, Raj Chari, Samuel F. Gilbert, Thomas S.K. Gilbert, Shashikala Ratnayake, Binwu Tang, Markus Hafner, Qingrong Chen, Daoud Meerzaman, Edwin J. Iwanowicz, Christina M. Annunziata, Lee M. Graves, Stanley Lipkowitz	2022	21
20	Identification of novel and potent isoquinoline aminooxazole-Based IMPDH inhibitors Bioorganic & Medicinal Chemistry Letters ·Ping Chen, Derek Norris, K.D. Haslow, T. G. Murali Dhar, William J. Pitts, Scott H. Watterson, Daniel L. Cheney, Donna A. Bassolino, Catherine Fleener, Katherine A. Rouleau, Diane Hollenbaugh, Robert M. Townsend, Joel C. Barrish, Edwin J. Iwanowicz	2003	21

About Edwin J. Iwanowicz

Edwin J. Iwanowicz is a scholar working on Molecular Biology, Organic Chemistry, Physiology, Oncology and Epidemiology, having authored 44 papers that have together received 1.1k indexed citations. Recurring topics across this work include Biochemical and Molecular Research (13 papers), Chemical Synthesis and Analysis (10 papers), Adenosine and Purinergic Signaling (8 papers), Cytomegalovirus and herpesvirus research (7 papers), Peptidase Inhibition and Analysis (6 papers), HIV/AIDS drug development and treatment (5 papers), Blood Coagulation and Thrombosis Mechanisms (4 papers) and Synthesis and Biological Evaluation (4 papers). The work is most often cited by research in Organic Chemistry (561 citations), Physiology (74 citations), Molecular Biology (577 citations), Hematology (60 citations) and Genetics (54 citations). Edwin J. Iwanowicz has collaborated with scholars based in United States, Germany and Australia. Frequent co-authors include James C. Lin, Michael A. Poss, R. H. Schlessinger, Joel C. Barrish, Zhengxiang Gu, T. G. Murali Dhar, James P. Springer, Diane Hollenbaugh, Steven M. Seiler and Daniel G. Roberts. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Tetrahedron Letters, Journal of Medicinal Chemistry, Blood and Structure.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Edwin J. Iwanowicz

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