D.O. Somers

1.6k citations

18 papers · 1.2k · h-index 14

Impact in

Virology top 2%
- HIV Research and Treatment
Infectious Diseases top 5%
- HIV/AIDS drug development and treatment
- HIV/AIDS Research and Interventions

Papers in

Molecular Biology 10
- Biochemical and Molecular Research 4
- Melanoma and MAPK Pathways 3
Infectious Diseases 6
- HIV/AIDS drug development and treatment 6

Co-authors: D.K. Stammers (6 shared papers)Robert Esnouf (3 shared papers)David I. Stuart (4 shared papers)Carl Ross (4 shared papers)E. Yvonne Jones (4 shared papers)Elspeth F. Garman (4 shared papers)J.N. Champness (2 shared papers)Aniruddha Achari (2 shared papers)
Journals: Bioorganic & Medicinal Chemistry Letters (3 papers)Organic Letters (2 papers)Journal of Medicinal Chemistry (2 papers)Journal of Crystal Growth (1 paper)ACS Medicinal Chemistry Letters (1 paper)
Partner nations: United Kingdom United States Ireland

In The Last Decade

D.O. Somers

18 papers receiving 1.2k citations

Peers

Countries citing papers authored by D.O. Somers

Since Specialization

Citations

This map shows the geographic impact of D.O. Somers's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by D.O. Somers with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites D.O. Somers more than expected).

Fields of papers citing papers by D.O. Somers

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by D.O. Somers. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by D.O. Somers. The network helps show where D.O. Somers may publish in the future.

Co-authors

The 25 scholars most cited alongside D.O. Somers, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with D.O. Somers Line = papers co-authored together D.O. Somers links everyone, so they are left out of the graph.

All Works

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18 of 18 papers shown

#	Work
1	High resolution structures of HIV-1 RT from four RT–inhibitor complexes Nature Structural & Molecular Biology ·Jingshan Ren, Robert Esnouf, Elspeth F. Garman, D.O. Somers, Carl Ross, Ian Kirby, James Keeling, G. Darby, E. Yvonne Jones, David I. Stuart, D.K. Stammers	1995	437
2	Crystal structure of the anti-bacterial sulfonamide drug target dihydropteroate synthase Nature Structural Biology ·Aniruddha Achari, D.O. Somers, J.N. Champness, P.K. Bryant, J. Rosemond, D.K. Stammers	1997	236
3	CSAR 2014: A Benchmark Exercise Using Unpublished Data from Pharma Journal of Chemical Information and Modeling ·Heather A. Carlson, Richard D. Smith, Kelly L. Damm‐Ganamet, Jeanne A. Stuckey, Aqeel Ahmed, M.A. Convery, D.O. Somers, Michael Kranz, P.A. Elkins, Guanglei Cui, Catherine E. Peishoff, Millard H. Lambert, James B. Dunbar	2016	82
4	N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)amides as potent, selective, inhibitors of JNK2 and JNK3 Bioorganic & Medicinal Chemistry Letters ·Richard Angell, Francis Atkinson, Murray J. B. Brown, Tsu Tshen Chuang, J.A. Christopher, Maria A. Cichy-Knight, Allison K. Dunn, Kendra E. Hightower, Susanna Malkakorpi, James R. Musgrave, Margarete Neu, Paul Rowland, Robyn Shea, Jeffery L. Smith, D.O. Somers, Sonia Thomas, Gladstone Thompson, Ruolan Wang	2006	70
5	Crystals of HIV-1 Reverse Transcriptase Diffracting to 2·2 Å Resolution Journal of Molecular Biology ·D.K. Stammers, D.O. Somers, Carl Ross, Ilsa T. Kirby, Pampa Ray, J E Wilson, Mark H. Norman, J.S. Ren, Robert Esnouf, Elspeth F. Garman, E. Yvonne Jones, David I. Stuart	1994	54
6	2.0 Å X‐ray structure of the ternary complex of 7,8‐dihydro‐6‐hydroxymethylpterinpyrophosphokinase from Escherichia coli with ATP and a substrate analogue FEBS Letters ·D.K. Stammers, Aniruddha Achari, D.O. Somers, P.K. Bryant, J. Rosemond, David L. Scott, J.N. Champness	1999	48
7	Continuous and Discontinuous Changes in the Unit Cell of HIV-1 Reverse Transcriptase Crystals on Dehydration Acta Crystallographica Section D Biological Crystallography ·Robert Esnouf, Jingshan Ren, Elspeth F. Garman, D.O. Somers, Carl Ross, E. Yvonne Jones, D.K. Stammers, David I. Stuart	1998	44
8	p38α Mitogen-Activated Protein Kinase Inhibitors: Optimization of a Series of Biphenylamides to Give a Molecule Suitable for Clinical Progression Journal of Medicinal Chemistry ·Natalie E. Aston, Paul Bamborough, Jacqueline B. Buckton, Christopher D. Edwards, Duncan S. Holmes, Katherine L. Jones, Vipulkumar K. Patel, Penny A. Smee, D.O. Somers, Giovanni Vitulli, Ann L. Walker	2009	35
9	Biphenyl amide p38 kinase inhibitors 1: Discovery and binding mode Bioorganic & Medicinal Chemistry Letters ·Richard Angell, Paul Bamborough, Anne Cleasby, Stuart Cockerill, Katherine L. Jones, Christopher J. Mooney, D.O. Somers, Ann L. Walker	2007	32
10	The structure of 6-phosphogluconate dehydrogenase refined at 2.5 Å resolution Acta Crystallographica Section B Structural Science ·Margaret Adams, S. Gover, R. Leaback, Christopher Phillips, D.O. Somers	1991	32
11	Structurally Diverse Mitochondrial Branched Chain Aminotransferase (BCATm) Leads with Varying Binding Modes Identified by Fragment Screening Journal of Medicinal Chemistry ·Alan D. Borthwick, Nicolas Ancellin, Sophie M. Bertrand, Ryan P. Bingham, Paul S. Carter, Chun‐wa Chung, Ian Churcher, Nérina Dodic, Charlène Fournier, Peter Francis, Andrew N. Hobbs, Craig Jamieson, Stephen D. Pickett, Sarah E. Smith, D.O. Somers, Claus Spitzfaden, Colin J. Suckling, Robert J. Young	2016	27
12	Discovery of potent and selective Spleen Tyrosine Kinase inhibitors for the topical treatment of inflammatory skin disease Bioorganic & Medicinal Chemistry Letters ·Michael D. Barker, John Liddle, Francis Atkinson, David M. Wilson, Marion C. Dickson, César Ramírez-Molina, Huw D. Lewis, Rob P. Davis, D.O. Somers, Margarete Neu, Emma J. Jones, Robert J. Watson	2018	18
13	Sheep 6-phosphogluconate dehydrogenase. Revised protein sequence based upon the sequences of cDNA clones obtained with the polymerase chain reaction Biochemical Journal ·D.O. Somers, S M Medd, John E. Walker, Margaret Adams	1992	17
14	Identification of a Novel and Selective Series of Itk Inhibitors via a Template-Hopping Strategy ACS Medicinal Chemistry Letters ·Catherine M. Alder, Martin Ambler, Amanda Campbell, Aurélie C. Champigny, Angela M. Deakin, John D. Harling, Carol Harris, Tim Longstaff, Sean M. Lynn, Aoife C. Maxwell, Chris J. Mooney, Callum Scullion, Onkar Singh, Ian E. Smith, D.O. Somers, Christopher J. Tame, Gareth Wayne, Caroline Wilson, James M. Woolven	2013	16
15	Pyrrolidine-5,5-trans-lactams. 4. Incorporation of a P3/P4 Urea Leads to Potent Intracellular Inhibitors of Hepatitis C Virus NS3/4A Protease Organic Letters ·Martin J. Slater, Elizabeth M. Amphlett, David Andrews, Paul Bamborough, Seb J. Carey, Martin R. Johnson, Paul S. Jones, Gail Mills, N. R. Parry, D.O. Somers, Alan J. Stewart, Tadeusz Skarżyński	2003	11
16	Pyrrolidine-5,5-trans-lactams. 2. The Use of X-ray Crystal Structure Data in the Optimization of P3 and P4 Substituents Organic Letters ·David Andrews, Helene Chaignot, Barry A. Coomber, Andrew C. Good, S. Lucy Hind, Martin R. Johnson, Paul S. Jones, Gail Mills, John Robinson, Tadeusz Skarżyński, Martin J. Slater, D.O. Somers	2002	11
17	The growth and characterization of crystals of human immunodeficiency virus (HIV) reverse transcriptase Journal of Crystal Growth ·E. Yvonne Jones, David I. Stuart, Elspeth F. Garman, Robert E. Griest, D.C. Phillips, G.L. Taylor, O. Matsumoto, G. Darby, Brendan Larder, Denise M. Lowe, K. L. Powell, D. J. M. Purifoy, Carl Ross, D.O. Somers, Margaret Tisdale, D.K. Stammers	1993	6
18	A two-step purification procedure for sheep liver 6-phosphogluconate dehydrogenase Protein Expression and Purification ·D.O. Somers, János Hajdu, Margaret Adams	1991	3

About D.O. Somers

D.O. Somers is a scholar working on Molecular Biology, Infectious Diseases, Virology, Materials Chemistry and Organic Chemistry, having authored 18 papers that have together received 1.2k indexed citations. Recurring topics across this work include HIV/AIDS drug development and treatment (6 papers), HIV Research and Treatment (4 papers), Biochemical and Molecular Research (4 papers), Enzyme Structure and Function (4 papers), Metabolism and Genetic Disorders (3 papers), Melanoma and MAPK Pathways (3 papers), Hepatitis C virus research (3 papers) and Computational Drug Discovery Methods (2 papers). The work is most often cited by research in Virology (381 citations), Infectious Diseases (537 citations), Computational Theory and Mathematics (166 citations), Molecular Biology (651 citations) and Organic Chemistry (253 citations). D.O. Somers has collaborated with scholars based in United Kingdom, United States and Ireland. Frequent co-authors include D.K. Stammers, Robert Esnouf, David I. Stuart, Carl Ross, E. Yvonne Jones, Elspeth F. Garman, J.N. Champness, Aniruddha Achari, Jingshan Ren and G. Darby. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Organic Letters, Journal of Medicinal Chemistry, Journal of Crystal Growth and ACS Medicinal Chemistry Letters.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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