Dirk Holzinger

6.9k citations
93 papers · 4.0k · 1 hit paper · h-index 33

Impact in

  • Hematology top 0.5%
    • Autoimmune and Inflammatory Disorders Research
  • Immunology top 2%
    • Immune Response and Inflammation
    • Immune Cell Function and Interaction

Papers in

  • Hematology 33
    • Autoimmune and Inflammatory Disorders Research 31
  • Immunology 28
    • Immune Response and Inflammation 11
    • Immunodeficiency and Autoimmune Disorders 6
    • IL-33, ST2, and ILC Pathways 5
Co-authors
Johannes Roth (29 shared papers)Dirk Foell (32 shared papers)Christoph Kessel (13 shared papers)Bettina Löffler (6 shared papers)Georg Peters (4 shared papers)Muzaffar Hussain (3 shared papers)Richard A. Proctor (2 shared papers)Silke Niemann (3 shared papers)
Journals
Pediatric Rheumatology (10 papers)Arthritis & Rheumatology (7 papers)Annals of the Rheumatic Diseases (6 papers)Arthritis Research & Therapy (3 papers)Journal of Allergy and Clinical Immunology (3 papers)
Partner nations
GermanyNetherlandsUnited States

In The Last Decade

Dirk Holzinger

86 papers receiving 3.9k citations

Dirk Holzinger's Hit Papers

Interleukin-18 diagnostically distinguishes and pathogenically promotes human and murine macrophage activation syndrome 2018 · 293 citations
2930+2+5Years since publication50100150200250
What are hit papers?

Paper score: A paper's citations measured against the top-1% bar of its own field and year: the square root of citations ÷ bar, so 1 means right at the bar and 2 means four times its citations. The bar blends the citation counts that enter the top 1% of the paper's subfields in its year (weighted 89.5%), of those subfields over all years (0.5%) and of its year across all fields (10%); a subfield and year with fewer than 400 papers takes its year's bar. Papers from 2026 are not scored yet: in an unfinished year, when a paper appeared matters more than how it is cited.

Hit paper: A paper cited at least 1.5× the top-1% bar of its field and year: a paper score of at least √1.5.

  1. 2018 Blood

Peers

Dirk Holzinger
Comparison fields: 5 of 111
  • Hematology 1.1k
  • Immunology 1.3k
  • Infectious Diseases 744
  • Speech and Hearing 231
  • Rheumatology 440
Replace Grant S. Schulert with:
Grant S. Schulert United States
Hidetoshi Takada Japan
HANS OLE MADSEN Denmark
Jaak M J J Vossen Netherlands
JUSTEN H. PASSWELL Israel
Stefan Schwartz Germany
Kazunaga Agematsu Japan
Richard Mouy France
Carlos R. Abramowsky United States
Carol J. Landers United States
Dirk Holzinger relative to Grant S. Schulert United States Grant S. Schulert's profile →
Citations per field
00.5×2×3.1×
Grant S. Schulert · 1×
Citations per year

Countries citing papers authored by Dirk Holzinger

Since Specialization
Citations

This map shows the geographic impact of Dirk Holzinger's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Dirk Holzinger with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Dirk Holzinger more than expected).

Fields of papers citing papers by Dirk Holzinger

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Dirk Holzinger. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Dirk Holzinger. The network helps show where Dirk Holzinger may publish in the future.

Co-authors

The 25 scholars most cited alongside Dirk Holzinger, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Dirk Holzinger Line = papers co-authored together Dirk Holzinger links everyone, so they are left out of the graph.

All Works

20 of 20 papers shown

Showing the 20 most-cited of 93 papers — load more, or switch the sort, to bring in the rest.

#Work
1
Staphylococcus aureus phenotype switching: an effective bacterial strategy to escape host immune response and establish a chronic infection
EMBO Molecular Medicine ·Lorena P. N. Tuchscherr, Eva Medina, Muzaffar Hussain, Wolfgang Völker, Vanessa Heitmann, Silke Niemann, Dirk Holzinger, Johannes Roth, Richard A. Proctor, Karsten Becker, Georg Peters, Bettina Löffler
2011372
2
Staphylococcus aureus Panton-Valentine Leukocidin Is a Very Potent Cytotoxic Factor for Human Neutrophils
PLoS Pathogens ·Bettina Löffler, Muzaffar Hussain, Matthias Grundmeier, Michaela Brück, Dirk Holzinger, Georg Varga, Johannes Roth, Barbara C. Kahl, Richard A. Proctor, Georg Peters
2010359
3
Interleukin-18 diagnostically distinguishes and pathogenically promotes human and murine macrophage activation syndrome
Blood ·Eric S. Weiss, Charlotte Girard, Dirk Holzinger, Adriana A. de Jesus, Zeshan Tariq, Jennifer Lee Picarsic, Eduardo Jorge Schiffrin, Dirk Foell, Alexei A. Grom, Sandra Ammann, Stephan R. Ehl, Tomoaki Hoshino, Raphaela T. Goldbach‐Mansky, Cem Gabay, Scott Canna
Hit paper breakdown →		2018293
4
Effectiveness of First‐Line Treatment With Recombinant Interleukin‐1 Receptor Antagonist in Steroid‐Naive Patients With New‐Onset Systemic Juvenile Idiopathic Arthritis: Results of a Prospective Cohort Study
Arthritis & Rheumatology ·Sebastiaan J. Vastert, Wilco de Jager, Bo Jan Noordman, Dirk Holzinger, Wietse Kuis, Berent J. Prakken, Nico Wulffraat
2013204
5
Induction of MxA Gene Expression by Influenza A Virus Requires Type I or Type III Interferon Signaling
Journal of Virology ·Dirk Holzinger, Carl Jorns, Silke Stertz, Stéphanie Boisson‐Dupuis, Robert Thimme, Manfred Weidmann, J. Casanova, Otto Haller, Georg Kochs
2007202
6
Staphylococcus aureus Panton-Valentine leukocidin induces an inflammatory response in human phagocytes via the NLRP3 inflammasome
Journal of Leukocyte Biology ·Dirk Holzinger, Laura Gieldon, Vijayashree Mysore, Nadine Nippe, Debra J. Taxman, Joseph A. Duncan, Peter M. Broglie, Kristina Marketon, Judith Austermann, Thomas Vogl, Dirk Foell, Silke Niemann, Georg Peters, Johannes Roth, Bettina Löffler
2012142
7
Phagocyte-derived S100 proteins in autoinflammation: Putative role in pathogenesis and usefulness as biomarkers
Clinical Immunology ·Christoph Kessel, Dirk Holzinger, Dirk Foell
2012137
8
The Toll-like receptor 4 agonist MRP8/14 protein complex is a sensitive indicator for disease activity and predicts relapses in systemic-onset juvenile idiopathic arthritis
Annals of the Rheumatic Diseases ·Dirk Holzinger, Michael Frosch, Astrid Kastrup, Femke H. M. Prince, Marieke H. Otten, Lisette W. A. van Suijlekom‐Smit, Rebecca Ten Cate, Esther P A H Hoppenreijs, Sandra Hansmann, Halima Moncrieffe, Simona Ursu, Lucy R. Wedderburn, Johannes Roth, Dirk Foell, Helmut Wittkowski
2012132
9
Treatment to Target Using Recombinant Interleukin‐1 Receptor Antagonist as First‐Line Monotherapy in New‐Onset Systemic Juvenile Idiopathic Arthritis: Results From a Five‐Year Follow‐Up Study
Arthritis & Rheumatology ·Nienke M. ter Haar, E. H. Pieter van Dijkhuizen, Joost Frans Swart, Annet van Royen‐Kerkhof, Ayman El Idrissi, A. Leek, Wilco de Jager, Mark de Groot, Saskia Haitjema, Dirk Holzinger, Dirk Foell, Jorg van Loosdregt, Nico Wulffraat, Sytze de Roock, Sebastiaan J. Vastert
2019129
10
MRP8/14 serum levels as a strong predictor of response to biological treatments in patients with rheumatoid arthritis
Annals of the Rheumatic Diseases ·Ivy Y. K. Choi, Daniëlle M. Gerlag, Marieke J Herenius, Rogier M. Thurlings, Carla Ann Wijbrandts, Dirk Foell, Thomas Vogl, Johannes Roth, Paul Peter Tak, Dirk Holzinger
2013127
11
The danger from within: alarmins in arthritis
Nature Reviews Rheumatology ·Meriam Nefla, Dirk Holzinger, F. Berenbaum, Claire Jacques
2016123
12
Periodic fever, aphthous stomatitis, pharyngitis, cervical adenitis syndrome is linked to dysregulated monocyte IL-1β production
Journal of Allergy and Clinical Immunology ·Laeticia Kolly, Nathalie Busso, Annette von Scheven-Gête, Nathaliane Bagnoud, Isabelle Moix, Dirk Holzinger, Gregoire Simon, Annette Ives, Greta Guarda, Alexander K.-L. So, Michael A. Morris, Michaël Hofer
2012122
13
A subgroup of juvenile idiopathic arthritis patients who respond well to methotrexate are identified by the serum biomarker MRP8/14 protein
Lara D. Veeken ·Halima Moncrieffe, Simona Ursu, Dirk Holzinger, Fiona Patrick, Laura Kassoumeri, Angie Wade, Johannes Roth, Lucy R. Wedderburn
201380
14
Proinflammatory Cytokine Environments Can Drive Interleukin‐17 Overexpression by γ/δ T Cells in Systemic Juvenile Idiopathic Arthritis
Arthritis & Rheumatology ·Christoph Kessel, Katrin Lippitz, Toni Weinhage, Claas Heinrich Hinze, Helmut Wittkowski, Dirk Holzinger, Ndate Fall, Alexei A. Grom, Niklas Gruen, Dirk Foell
201772
15
Myeloid‐Related Proteins 8 and 14 Contribute to Monosodium Urate Monohydrate Crystal–Induced Inflammation in Gout
Arthritis & Rheumatology ·Dirk Holzinger, Nadine Nippe, Thomas Vogl, Kristina Marketon, Vijayashree Mysore, Toni Weinhage, Nicola Dalbeth, Bregina Pool, Tony Raymond Merriman, Dominique Baeten, Annette Ives, Nathalie Busso, Dirk Foell, Sylvette Bas, Cem Gabay, Johannes Roth
201463
16
Alarming consequences – autoinflammatory disease spectrum due to mutations in proline-serine-threonine phosphatase-interacting protein 1
Current Opinion in Rheumatology ·Dirk Holzinger, Johannes Roth
201661
17
MRP8/14 serum levels as a predictor of response to starting and stopping anti-TNF treatment in juvenile idiopathic arthritis
Arthritis Research & Therapy ·Janneke Anink, Lisette W. A. van Suijlekom‐Smit, Marieke H. Otten, Femke H. M. Prince, Marion A. J. van Rossum, Koert M. Dolman, Esther P A H Hoppenreijs, Rebecca Ten Cate, Simona Ursu, Lucy R. Wedderburn, Gerd Horneff, Michael Frosch, Thomas Vogl, Faekah Gohar, Dirk Foell, Johannes Roth, Dirk Holzinger
201561
18
Elevated S100A8/A9 and S100A12 Serum Levels Reflect Intraocular Inflammation in Juvenile Idiopathic Arthritis-Associated Uveitis: Results From a Pilot Study
Investigative Ophthalmology & Visual Science ·Karoline Walscheid, Arnd Heiligenhaus, Dirk Holzinger, Johannes Roth, Carsten Heinz, Christoph Tappeiner, Maren Kasper, Dirk Foell
201561
19
IL-6 Amplifies TLR Mediated Cytokine and Chemokine Production: Implications for the Pathogenesis of Rheumatic Inflammatory Diseases
PLoS ONE ·Ivan Caiello, Gaetana Minnone, Dirk Holzinger, Thomas Vogl, Giusi Prencipe, Antonio Manzo, Fabrizio De Benedetti, Raffaele Strippoli
201459
20
Among the S100 proteins, S100A12 is the most significant marker for psoriasis disease activity
Journal of the European Academy of Dermatology and Venereology ·Dagmar Wilsmann‐Theis, Julia Wagenpfeil, Dirk Holzinger, Johannes Roth, Susanne Koch, Sylvia Schnautz, Thomas R.M. Bieber, Joerg Wenzel
201558

About Dirk Holzinger

Dirk Holzinger is a scholar working on Hematology, Immunology, Speech and Hearing, Molecular Biology and Rheumatology, having authored 93 papers that have together received 4.0k indexed citations. Recurring topics across this work include Inflammasome and immune disorders (34 papers), Autoimmune and Inflammatory Disorders Research (31 papers), S100 Proteins and Annexins (13 papers), Immune Response and Inflammation (11 papers), Adolescent and Pediatric Healthcare (10 papers), Immunodeficiency and Autoimmune Disorders (6 papers), IL-33, ST2, and ILC Pathways (5 papers) and Antimicrobial Resistance in Staphylococcus (5 papers). The work is most often cited by research in Hematology (1.1k citations), Immunology (1.3k citations), Infectious Diseases (744 citations), Speech and Hearing (231 citations) and Rheumatology (440 citations). Dirk Holzinger has collaborated with scholars based in Germany, Netherlands and United States. Frequent co-authors include Johannes Roth, Dirk Foell, Christoph Kessel, Bettina Löffler, Georg Peters, Muzaffar Hussain, Richard A. Proctor, Silke Niemann, Sebastiaan J. Vastert and Wilco de Jager. Their work appears in journals such as Pediatric Rheumatology, Arthritis & Rheumatology, Annals of the Rheumatic Diseases, Arthritis Research & Therapy and Journal of Allergy and Clinical Immunology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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