David C. Rees

25.0k citations

326 papers · 15.4k · 6 hit papers · h-index 54

Impact in

Genetics top 0.05%
- Hemoglobinopathies and Related Disorders
Hematology top 0.1%
- Iron Metabolism and Disorders
- Blood groups and transfusion
- Blood Coagulation and Thrombosis Mechanisms

Papers in

Genetics 181
- Hemoglobinopathies and Related Disorders 176
Hematology 121
- Iron Metabolism and Disorders 92
- Blood groups and transfusion 35

Co-authors: Thomas N. Williams (8 shared papers)Mark T. Gladwin (1 shared paper)Christopher W. Murray (6 shared papers)J. B. Clegg (6 shared papers)Michael J. Cox (3 shared papers)Pedro H. H. Hermkens (5 shared papers)H. C. J. OTTENHEIJM (6 shared papers)Frédéric B. Piel (4 shared papers)
Journals: British Journal of Haematology (45 papers)Blood (32 papers)Journal of Medicinal Chemistry (10 papers)Haematologica (9 papers)HemaSphere (8 papers)
Partner nations: United Kingdom United States France

In The Last Decade

David C. Rees

316 papers receiving 14.9k citations

David C. Rees's Hit Papers

6 papers align trajectories log scale

Sickle Cell Disease 2017 · 780 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2017 New England Journal of Medicine
2014 Nature Reviews Drug Discovery
2010 The Lancet
2009 Nature Chemistry
1995 The Lancet
1986 Proceedings of the National Academy of Sciences

Peers

Replace William D. Figg with:

William D. Figg United States

Scott H. Kaufmann United States

Eleftherios P. Diamandis Canada

Howard L. McLeod United States

Elisabeth G.E. de Vries Netherlands

Michael S. Pepper South Africa

Seppo Ylä‐Herttuala Finland

Susan E. Bates United States

Edward A. Sausville United States

Takashi Tsuruo Japan

David C. Rees relative to William D. Figg United States William D. Figg's profile →

Citations per field

00.5×2×4×6.7×

William D. Figg · 1×

×5.2 6k/1k

GENET

×2.3 4k/2k

HEMAT

×6.7 495/74

IM

×1.7 1k/808

PPCH

×0.5 5k/10k

MB

Citations per year

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Countries citing papers authored by David C. Rees

Since Specialization

Citations

This map shows the geographic impact of David C. Rees's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David C. Rees with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David C. Rees more than expected).

Fields of papers citing papers by David C. Rees

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David C. Rees. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David C. Rees. The network helps show where David C. Rees may publish in the future.

Co-authors

The 25 scholars most cited alongside David C. Rees, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with David C. Rees Line = papers co-authored together David C. Rees links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 326 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Sickle-cell disease The Lancet ·David C. Rees, Thomas N. Williams, Mark T. Gladwin Hit paper breakdown →	2010	1709
2	World distribution of factor V Leiden The Lancet ·David C. Rees, Michael J. Cox, J. B. Clegg Hit paper breakdown →	1995	903
3	The role of ligand efficiency metrics in drug discovery Nature Reviews Drug Discovery ·Andrew L. Hopkins, György M. Keserű, Paul D. Leeson, David C. Rees, Charles H. Reynolds Hit paper breakdown →	2014	839
4	Sickle Cell Disease New England Journal of Medicine ·Frédéric B. Piel, Martin H. Steinberg, David C. Rees Hit paper breakdown →	2017	780
5	The rise of fragment-based drug discovery Nature Chemistry ·Christopher W. Murray, David C. Rees Hit paper breakdown →	2009	589
6	Global distribution of the CCR5 gene 32-basepair deletion Nature Genetics ·Jeremy Martinson, Nicola H. Chapman, David C. Rees, Yan‐Tat Liu, John Clegg	1997	420
7	Solid-phase organic reactions: A review of the recent literature Tetrahedron ·Pedro H. H. Hermkens, H. C. J. OTTENHEIJM, David C. Rees	1996	399
8	Solid-phase organic reactions II: A review of the literature Nov 95–Nov 96 Tetrahedron ·Pedro H. H. Hermkens, H. C. J. OTTENHEIJM, David C. Rees	1997	329
9	Hydrophobic Organization of Membrane Proteins Science ·David C. Rees, L. DeAntonio, David Eisenberg	1989	253
10	Fragment-based lead discovery: leads by design Drug Discovery Today ·Robin A. E. Carr, Miles Congreve, Christopher W. Murray, David C. Rees	2005	247
11	FLT3 internal tandem duplication mutations in adult acute myeloid leukaemia define a high-risk group British Journal of Haematology ·Faisel M. Abuduhier, Anne Goodeve, Gill Wilson, Mamdooh Gari, I. R. Peake, David C. Rees, Elisabeth Vandenberghe, Peter R. Winship, John T. Reilly	2000	241
12	Structural homology of reaction centers from Rhodopseudomonas sphaeroides and Rhodopseudomonas viridis as determined by x-ray diffraction. Proceedings of the National Academy of Sciences ·James P. Allen, G. Fehér, Todd O. Yeates, David C. Rees, J. Deisenhofer, Hartmut Michel, Robert Huber Hit paper breakdown →	1986	229
13	The 'rule of three' for fragment-based drug discovery: where are we now? Nature Reviews Drug Discovery ·Harren Jhoti, Glyn Williams, David C. Rees, Christopher W. Murray	2013	228
14	Novel mutations in PIEZO1 cause an autosomal recessive generalized lymphatic dysplasia with non-immune hydrops fetalis Nature Communications ·Elisavet Fotiou, Silvia Martin‐Almedina, Michael A. Simpson, Shin Lin, Kristiana Gordon, Glen Brice, Giles Atton, Iona Jeffery, David C. Rees, Cyril Mignot, Julie Vogt, Tessa Homfray, M Snyder, Stanley G. Rockson, Steve Jeffery, Peter Mortimer, Sahar Mansour, Pia Østergaard	2015	226
15	Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency Human Genetics ·Satoshi Sumi, Anthony M. Marinaki, Monica Arenas, Lynette D. Fairbanks, M Shobowale-Bakre, David C. Rees, Swee Lay Thein, Azhar Ansari, Jeremy Sanderson, Ronney A. De Abreu, Anne Simmonds, John A. Duley	2002	210
16	A left‐hand beta‐helix revealed by the crystal structure of a carbonic anhydrase from the archaeon Methanosarcina thermophila. The EMBO Journal ·Caroline Kisker, Hermann Schindelin, Birgit E. Alber, James G. Ferry, David C. Rees	1996	206
17	Significant haemoglobinopathies: guidelines for screening and diagnosis British Journal of Haematology ·Kate Ryan, Barbara J. Bain, David Worthington, Jacky A James, Dianne Plews, Anthony Mason, David Roper, David C. Rees, Barbara De la Salle, Allison Streetly	2010	183
18	Guidelines for the management of the acute painful crisis in sickle cell disease British Journal of Haematology ·David C. Rees, Ade D. Olujohungbe, Norman E. Parker, A. D. Stephens, Paul Telfer, Josh Wright	2003	174
19	The spleen and sickle cell disease: the sick(led) spleen British Journal of Haematology ·Valentine Brousse, Pierre Buffet, David C. Rees	2014	168
20	Solid-phase organic reactions III: A review of the literature Nov 96–Dec 97 Tetrahedron ·Susan E. Booth, Pedro H. H. Hermkens, H. C. J. OTTENHEIJM, David C. Rees	1998	157

About David C. Rees

David C. Rees is a scholar working on Genetics, Hematology, Molecular Biology, Pediatrics, Perinatology and Child Health and Physiology, having authored 326 papers that have together received 15.4k indexed citations. Recurring topics across this work include Hemoglobinopathies and Related Disorders (176 papers), Iron Metabolism and Disorders (92 papers), Erythrocyte Function and Pathophysiology (46 papers), Blood groups and transfusion (35 papers), Neonatal Health and Biochemistry (30 papers), Chemical Synthesis and Analysis (23 papers), Prenatal Screening and Diagnostics (17 papers) and Porphyrin Metabolism and Disorders (16 papers). The work is most often cited by research in Genetics (5.6k citations), Hematology (4.4k citations), Internal Medicine (495 citations), Pediatrics, Perinatology and Child Health (1.4k citations) and Molecular Biology (5.4k citations). David C. Rees has collaborated with scholars based in United Kingdom, United States and France. Frequent co-authors include Thomas N. Williams, Mark T. Gladwin, Christopher W. Murray, J. B. Clegg, Michael J. Cox, Pedro H. H. Hermkens, H. C. J. OTTENHEIJM, Frédéric B. Piel, Martin H. Steinberg and Andrew L. Hopkins. Their work appears in journals such as British Journal of Haematology, Blood, Journal of Medicinal Chemistry, Haematologica and HemaSphere.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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David C. Rees

David C. Rees's Hit Papers

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All Works

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