Christopher E. Shaw

57.8k citations
244 papers · 19.3k · 6 hit papers · h-index 70

Impact in

  • Neurology top 0.01%
    • Amyotrophic Lateral Sclerosis Research
    • Parkinson's Disease Mechanisms and Treatments
    • Neurological diseases and metabolism
  • Genetics top 0.02%
    • Neurogenetic and Muscular Disorders Research

Papers in

  • Neurology 180
    • Amyotrophic Lateral Sclerosis Research 172
    • Parkinson's Disease Mechanisms and Treatments 41
    • Neurological diseases and metabolism 24
  • Genetics 98
    • Neurogenetic and Muscular Disorders Research 96
Co-authors
Ammar Al‐Chalabi (79 shared papers)Christopher C.J. Miller (26 shared papers)P. Nigel Leigh (38 shared papers)Boris Rogelj (22 shared papers)Caroline Vance (31 shared papers)Steven Ackerley (14 shared papers)P. Nigel Leigh (27 shared papers)Agnes L. Nishimura (22 shared papers)
Journals
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration (15 papers)Journal of Neurology Neurosurgery & Psychiatry (12 papers)Neurobiology of Aging (12 papers)Human Molecular Genetics (10 papers)Brain (10 papers)
Partner nations
United KingdomUnited StatesSlovenia

In The Last Decade

Christopher E. Shaw

241 papers receiving 19.1k citations

Christopher E. Shaw's Hit Papers

Axonal Transport of TDP-43 mRNA Granules Is Impaired by ALS-Causing Mutations 2014 · 508 citations
5080+7+14Years since publication50010001.5k2.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

  • it has ≥500 total citations;
  • it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
  • it reaches the top citation threshold in at least one of its specific research topics.
  1. 2014 Neuron
  2. 2014 Nature Communications
  3. 2011 Human Molecular Genetics
  4. 2011 Nature Neuroscience
  5. 2008 Science
  6. 2004 Neurobiology of Disease

Peers

Christopher E. Shaw
Comparison fields: 5 of 168
  • Neurology 12.2k
  • Genetics 6.0k
  • Neurology 2.5k
  • Cellular and Molecular Neuroscience 2.7k
  • Molecular Biology 8.3k
Replace Aaron D. Gitler with:
Aaron D. Gitler United States
Rosa Rademakers United States
Nereo Bresolin Italy
Peter Heutink Netherlands
Kenneth H. Fischbeck United States
Giacomo P. Comi Italy
Brian K. Kaspar United States
Shoji Tsuji Japan
Linda Greensmith United Kingdom
John W. Griffin United States
Christopher E. Shaw relative to Aaron D. Gitler United States Aaron D. Gitler's profile →
Citations per field
00.5×2×2.6×
Aaron D. Gitler · 1×
Citations per year

Countries citing papers authored by Christopher E. Shaw

Since Specialization
Citations

This map shows the geographic impact of Christopher E. Shaw's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christopher E. Shaw with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christopher E. Shaw more than expected).

Fields of papers citing papers by Christopher E. Shaw

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christopher E. Shaw. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christopher E. Shaw. The network helps show where Christopher E. Shaw may publish in the future.

Co-authors

The 25 scholars most cited alongside Christopher E. Shaw, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Christopher E. Shaw Line = papers co-authored together Christopher E. Shaw links everyone, so they are left out of the graph.

All Works

20 of 20 papers shown

Showing the 20 most-cited of 244 papers — load more, or switch the sort, to bring in the rest.

#Work
1
TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis
Science ·Jemeen Sreedharan, Ian P. Blair, Vineeta B. Tripathi, Xun Hu, Caroline Vance, Boris Rogelj, Steven Ackerley, Jennifer C. Durnall, Kelly L. Williams, Emanuele Buratti, Francisco E. Baralle, Jacqueline de Belleroche, John D. Mitchell, P. Nigel Leigh, Ammar Al‐Chalabi, Christopher C.J. Miller, Garth A. Nicholson, Christopher E. Shaw
Hit paper breakdown →		20082052
2
Characterizing the RNA targets and position-dependent splicing regulation by TDP-43
Nature Neuroscience ·James Tollervey, Tomaž Curk, Boris Rogelj, Michael Briese, Matteo Cereda, Melis Kayikci, Julian König, Tibor Hortobágyi, Agnes L. Nishimura, Vera Župunski, Rickie Patani, Siddharthan Chandran, Gregor Rot, Blaž Zupan, Christopher E. Shaw, Jernej Ule
Hit paper breakdown →		2011879
3
Evidence of widespread cerebral microglial activation in amyotrophic lateral sclerosis: an [11C](R)-PK11195 positron emission tomography study
Neurobiology of Disease ·Martin R. Turner, Annachiara Cagnin, Federico Turkheimer, Christopher C.J. Miller, Christopher E. Shaw, David J. Brooks, P. Nigel Leigh, Richard B. Banati
Hit paper breakdown →		2004594
4
Axonal Transport of TDP-43 mRNA Granules Is Impaired by ALS-Causing Mutations
Neuron ·Nael H. Alami, Rebecca B. Smith, Mónica A. Carrasco, Luis A. Williams, Christina S. Winborn, Steve S.W. Han, Evangelos Kiskinis, Brett J Winborn, Brian D. Freibaum, Anderson Kanagaraj, Alison J. Clare, Nisha M. Badders, Bilada Bilican, Edward Chaum, Siddharthan Chandran, Christopher E. Shaw, Kevin Eggan, Tom Maniatis, J. Paul Taylor
Hit paper breakdown →		2014508
5
ER–mitochondria associations are regulated by the VAPB–PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43
Nature Communications ·Radu Stoica, Kurt J. De Vos, Sébastien Paillusson, Sarah B. Mueller, Rosa M. Sancho, Kwok‐Fai Lau, Gema Vizcay‐Barrena, Wen-Lang Lin, Ya-Fei Xu, Jada Lewis, Dennis W. Dickson, Leonard Petrucelli, Jacqueline C. Mitchell, Christopher E. Shaw, Christopher C.J. Miller
Hit paper breakdown →		2014505
6
VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis
Human Molecular Genetics ·Kurt J. De Vos, Gábor M. Mórotz, Radu Stoica, Elizabeth L. Tudor, Kwok‐Fai Lau, Steven Ackerley, Alice Warley, Christopher E. Shaw, Christopher C.J. Miller
Hit paper breakdown →		2011470
7
p62 positive, TDP-43 negative, neuronal cytoplasmic and intranuclear inclusions in the cerebellum and hippocampus define the pathology of C9orf72-linked FTLD and MND/ALS
Acta Neuropathologica ·Safa Al‐Sarraj, Andrew King, Claire Troakes, Bradley Smith, Satomi Maekawa, István Bódi, Boris Rogelj, Ammar Al‐Chalabi, Tibor Hortobágyi, Christopher E. Shaw
2011371
8
Hexanucleotide Repeats in ALS/FTD Form Length-Dependent RNA Foci, Sequester RNA Binding Proteins, and Are Neurotoxic
Cell Reports ·Youn‐Bok Lee, Han-Jou Chen, João Peres, Jorge Gomez-Deza, Jan Attig, Maja Štalekar, Claire Troakes, Agnes L. Nishimura, Emma L. Scotter, Caroline Vance, Yoshitsugu Adachi, Valentina Sardone, Jack W. Miller, Bradley Smith, Jean‐Marc Gallo, Jernej Ule, Frank Hirth, Boris Rogelj, Corinne Houart, Christopher E. Shaw
2013369
9
Proteome-based plasma biomarkers for Alzheimer's disease
Brain ·Abdul Hye, Steven Lynham, Madhav Thambisetty, (unknown), James Campbell, Helen L. Byers, Claudie Hooper, Frühling Rijsdijk, Sarah J. Tabrizi, Steven J. Banner, Christopher E. Shaw, C. Foy, Michaela Poppe, Nicola Archer, Gillian Hamilton, John Powell, Richard G. Brown, Pak Sham, Malcolm Ward, Simon Lovestone
2006355
10
ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43
Proceedings of the National Academy of Sciences ·Eveline S. Arnold, Shuo‐Chien Ling, Stephanie C. Huelga, Clotilde Lagier‐Tourenne, Magdalini Polymenidou, Dara Ditsworth, Holly Kordasiewicz, Melissa McAlonis‐Downes, Oleksandr Platoshyn, Philippe A. Parone, Sandrine Da Cruz, Kevin M. Clutario, Debbie Swing, Lino Tessarollo, Martin Maršala, Christopher E. Shaw, G Yeo, Don W. Cleveland
2013348
11
Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models
Nature Chemical Biology ·Sami J. Barmada, Andrea Serio, Arpana Arjun, Bilada Bilican, Aaron Daub, D. Michael Ando, Andrey S. Tsvetkov, Michael A. Pleiss, Xingli Li, Daniel Peisach, Christopher E. Shaw, Siddharthan Chandran, Steven Finkbeiner
2014344
12
Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content
Human Molecular Genetics ·Kurt J. De Vos, Anna Chapman, Maria E. Tennant, Catherine Manser, Elizabeth L. Tudor, Kwok‐Fai Lau, Janet Brownlees, Steven Ackerley, Pamela J. Shaw, Declan M. McLoughlin, Christopher E. Shaw, P. Nigel Leigh, Christopher C.J. Miller, Andrew J. Grierson
2007328
13
A proposed staging system for amyotrophic lateral sclerosis
Brain ·J.C. Roche, Ricard Rojas‐García, Kirsten M. Scott, William J. Scotton, Catherine Ellis, Rachel Burman, Lokesh Wijesekera, Martin R. Turner, P. Nigel Leigh, Christopher E. Shaw, Ammar Al‐Chalabi
2012327
14
Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy
Proceedings of the National Academy of Sciences ·Andrea Serio, Bilada Bilican, Sami J. Barmada, D. Michael Ando, Chen Zhao, (unknown), Karen Burr, Ghazal Haghi, David Story, Agnes L. Nishimura, Mónica A. Carrasco, Hemali Phatnani, Carole Shum, Ian Wilmut, Tom Maniatis, Christopher E. Shaw, Steven Finkbeiner, Siddharthan Chandran
2013272
15
Familial amyotrophic lateral sclerosis with frontotemporal dementia is linked to a locus on chromosome 9p13.2–21.3
Brain ·Caroline Vance, Ammar Al‐Chalabi, Deborah Ruddy, Bradley Smith, Xun Hu, Jemeen Sreedharan, Teepu Siddique, Helenius J. Schelhaas, Benno Küsters, Dirk Troost, Frank Baas, Vianney de Jong, Christopher E. Shaw
2006269
16
Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability
Proceedings of the National Academy of Sciences ·Bilada Bilican, Andrea Serio, Sami J. Barmada, Agnes L. Nishimura, Gareth J. Sullivan, Mónica A. Carrasco, Hemali Phatnani, Clare A. Puddifoot, David Story, Judy Fletcher, In‐Hyun Park, Brad A. Friedman, George Q. Daley, David J. A. Wyllie, Giles E. Hardingham, Ian Wilmut, Steven Finkbeiner, Tom Maniatis, Christopher E. Shaw, Siddharthan Chandran
2012261
17
TDP-43 Proteinopathy and ALS: Insights into Disease Mechanisms and Therapeutic Targets
Neurotherapeutics ·Emma L. Scotter, Han-Jou Chen, Christopher E. Shaw
2015256
18
ALS/FTD‐associated FUS activates GSK‐3β to disrupt the VAPB–PTPIP51 interaction and ER–mitochondria associations
EMBO Reports ·Radu Stoica, Sébastien Paillusson, Patricia Gómez‐Suaga, Jacqueline C. Mitchell, Dawn H. W. Lau, Emma H. Gray, Rosa M. Sancho, Gema Vizcay‐Barrena, Kurt J. De Vos, Christopher E. Shaw, Diane P. Hanger, Wendy Noble, Christopher C.J. Miller
2016224
19
Human iPSC-derived motoneurons harbouring TARDBP or C9ORF72 ALS mutations are dysfunctional despite maintaining viability
Nature Communications ·Anna‐Claire Devlin, Karen Burr, Shyamanga Borooah, Joshua D. Foster, Elaine Cleary, Imbisaat Geti, Ludovic Vallier, Christopher E. Shaw, Siddharthan Chandran, Gareth B. Miles
2015220
20
Overexpression of human wild-type FUS causes progressive motor neuron degeneration in an age- and dose-dependent fashion
Acta Neuropathologica ·Jacqueline C. Mitchell, Philip McGoldrick, Caroline Vance, Tibor Hortobágyi, Jemeen Sreedharan, Boris Rogelj, Elizabeth L. Tudor, Bradley Smith, Christian Klasen, Christopher C.J. Miller, Jonathan D. Cooper, Linda Greensmith, Christopher E. Shaw
2012212

About Christopher E. Shaw

Christopher E. Shaw is a scholar working on Neurology, Genetics, Molecular Biology, Cellular and Molecular Neuroscience and Neurology, having authored 244 papers that have together received 19.3k indexed citations. Recurring topics across this work include Amyotrophic Lateral Sclerosis Research (172 papers), Neurogenetic and Muscular Disorders Research (96 papers), Parkinson's Disease Mechanisms and Treatments (41 papers), Neurological diseases and metabolism (24 papers), Alzheimer's disease research and treatments (20 papers), Prion Diseases and Protein Misfolding (19 papers), RNA Research and Splicing (15 papers) and Genetic Neurodegenerative Diseases (14 papers). The work is most often cited by research in Neurology (12.2k citations), Genetics (6.0k citations), Neurology (2.5k citations), Cellular and Molecular Neuroscience (2.7k citations) and Molecular Biology (8.3k citations). Christopher E. Shaw has collaborated with scholars based in United Kingdom, United States and Slovenia. Frequent co-authors include Ammar Al‐Chalabi, Christopher C.J. Miller, P. Nigel Leigh, Boris Rogelj, Caroline Vance, Steven Ackerley, P. Nigel Leigh, Agnes L. Nishimura, Tibor Hortobágyi and Siddharthan Chandran. Their work appears in journals such as Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, Journal of Neurology Neurosurgery & Psychiatry, Neurobiology of Aging, Human Molecular Genetics and Brain.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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