Christian Frezza

43.9k citations
191 papers · 34.4k · 16 hit papers · h-index 79

Impact in

    • Cancer, Hypoxia, and Metabolism
    • Mitochondrial Function and Pathology
    • ATP Synthase and ATPases Research
    • Epigenetics and DNA Methylation
    • Metabolomics and Mass Spectrometry Studies

Papers in

    • Cancer, Hypoxia, and Metabolism 64
    • Mitochondrial Function and Pathology 44
    • Epigenetics and DNA Methylation 34
    • RNA modifications and cancer 17
    • ATP Synthase and ATPases Research 16
    • Metabolomics and Mass Spectrometry Studies 15
    • Metabolism, Diabetes, and Cancer 12

Christian Frezza

181 papers receiving 34.0k citations

Christian Frezza's Hit Papers

Pro-inflammatory macrophages produce mitochondria-derived superoxide by reverse electron transport at complex I that regulates IL-1β release during NLRP3 inflammasome activation 2025 · 74 citations
740+6+12Years since publication10002.0k3.0k4.0k

Peers

Christian Frezza
Comparison fields: 5 of 179
  • Cancer Research 6.7k
  • Molecular Biology 19.1k
  • Immunology 5.6k
  • Clinical Biochemistry 1.8k
  • Biological Psychiatry 447
Replace Eyal Gottlieb with:
Eyal Gottlieb United Kingdom
Boris Zhivotovsky Sweden
Jason W. Locasale United States
Zheng Dong United States
Paolo Pinton Italy
Xiaodong Wang China
Paul Säftig Germany
Ira A. Tabas United States
Luca Scorrano Italy
Andreas Linkermann Germany
Christian Frezza relative to Eyal Gottlieb United Kingdom Eyal Gottlieb's profile →
Citations per field
00.5×1.5×2.2×
Eyal Gottlieb · 1×
Citations per year

Countries citing papers authored by Christian Frezza

Since Specialization
Citations

This map shows the geographic impact of Christian Frezza's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christian Frezza with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christian Frezza more than expected).

Fields of papers citing papers by Christian Frezza

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christian Frezza. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christian Frezza. The network helps show where Christian Frezza may publish in the future.

Co-authors

The 25 scholars most cited alongside Christian Frezza, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Christian Frezza Line = papers co-authored together Christian Frezza links everyone, so they are left out of the graph.

All Works

20 of 20 papers shown

Showing the 20 most-cited of 191 papers — load more, or switch the sort, to bring in the rest.

#Work
1
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Hit paper breakdown →
20164660
2
Succinate is an inflammatory signal that induces IL-1β through HIF-1α
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20133387
3
Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS
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20142335
4
Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages
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20161858
5
Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1
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20181521
6
OPA1 Controls Apoptotic Cristae Remodeling Independently from Mitochondrial Fusion
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20061390
7
Mitochondrial Cristae Shape Determines Respiratory Chain Supercomplexes Assembly and Respiratory Efficiency
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20131066
8
Organelle isolation: functional mitochondria from mouse liver, muscle and cultured filroblasts
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20071026
9 2006615
10
A Unifying Mechanism for Mitochondrial Superoxide Production during Ischemia-Reperfusion Injury
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2016606
11
Serine Is an Essential Metabolite for Effector T Cell Expansion
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2017558
12 2012549
13 2015509
14
Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition
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2016483
15 2011423
16 2011399
17 2009358
18
Crosstalk between mechanotransduction and metabolism
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2020338
19 2018308
20 2016294

About Christian Frezza

Christian Frezza is a scholar working on Cancer Research, Molecular Biology, Biochemistry, Immunology and Physiology, having authored 191 papers that have together received 34.4k indexed citations. Recurring topics across this work include Cancer, Hypoxia, and Metabolism (64 papers), Mitochondrial Function and Pathology (44 papers), Epigenetics and DNA Methylation (34 papers), RNA modifications and cancer (17 papers), ATP Synthase and ATPases Research (16 papers), Metabolomics and Mass Spectrometry Studies (15 papers), Metabolism, Diabetes, and Cancer (12 papers) and Immune cells in cancer (10 papers). The work is most often cited by research in Cancer Research (6.7k citations), Molecular Biology (19.1k citations), Immunology (5.6k citations), Clinical Biochemistry (1.8k citations) and Biological Psychiatry (447 citations). Christian Frezza has collaborated with scholars based in United Kingdom, Germany and United States. Frequent co-authors include Luca Scorrano, Sara Cipolat, Edoardo Gaude, Eyal Gottlieb, Marco Sciacovelli, Ana S.H. Costa, Michael P. Murphy, Bart De Strooper, Dylan G. Ryan and Tomasz Rudka. Their work appears in journals such as Nature, Nature Communications, Nature Metabolism, Cell Metabolism and Cell Reports.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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