Charles E. Lawrence

10.2k citations

89 papers · 7.5k · 2 hit papers · h-index 37

Impact in

Molecular Biology top 1%
- Genomics and Phylogenetic Studies
- Genomics and Chromatin Dynamics
- Protein Structure and Dynamics
- RNA and protein synthesis mechanisms
- Machine Learning in Bioinformatics
Aging top 5%

Papers in

Molecular Biology 62
- Genomics and Phylogenetic Studies 31
- Genomics and Chromatin Dynamics 15
- Protein Structure and Dynamics 12
- RNA and protein synthesis mechanisms 9
- RNA regulation and disease 4
- Fractal and DNA sequence analysis 4
Atmospheric Science 12
- Geology and Paleoclimatology Research 12

Co-authors: Jun S. Liu (10 shared papers)Andrew F. Neuwald (6 shared papers)Mark S. Boguski (1 shared paper)Stephen F. Altschul (1 shared paper)John C. Wootton (1 shared paper)Stephen H. Bryant (4 shared papers)Andrew A. Reilly (5 shared papers)Yong-Bin Ding (1 shared paper)
Journals: Proteins Structure Function and Bioinformatics (6 papers)Bioinformatics (6 papers)Nucleic Acids Research (5 papers)Journal of the American Statistical Association (3 papers)Computer applications in the biosciences (3 papers)
Partner nations: United States Russia China

In The Last Decade

Charles E. Lawrence

87 papers receiving 7.2k citations

Charles E. Lawrence's Hit Papers

align trajectories log scale

Toward a Cenozoic history of atmospheric CO 2 2023 · 138 citations

What are hit papers?

Paper score: A paper's citations measured against the top-1% bar of its own field and year: the square root of citations ÷ bar, so 1 means right at the bar and 2 means four times its citations. The bar blends the citation counts that enter the top 1% of the paper's subfields in its year (weighted 89.5%), of those subfields over all years (0.5%) and of its year across all fields (10%); a subfield and year with fewer than 400 papers takes its year's bar. Papers from 2026 are not scored yet: in an unfinished year, when a paper appeared matters more than how it is cited.

Hit paper: A paper cited at least 1.5× the top-1% bar of its field and year: a paper score of at least √1.5.

2023 Science
1993 Science

Peers

Countries citing papers authored by Charles E. Lawrence

Since Specialization

Citations

This map shows the geographic impact of Charles E. Lawrence's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Charles E. Lawrence with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Charles E. Lawrence more than expected).

Fields of papers citing papers by Charles E. Lawrence

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Charles E. Lawrence. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Charles E. Lawrence. The network helps show where Charles E. Lawrence may publish in the future.

Co-authors

The 25 scholars most cited alongside Charles E. Lawrence, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Charles E. Lawrence Line = papers co-authored together Charles E. Lawrence links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 89 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Detecting Subtle Sequence Signals: a Gibbs Sampling Strategy for Multiple Alignment Science ·Charles E. Lawrence, Stephen F. Altschul, Mark S. Boguski, Jun S. Liu, Andrew F. Neuwald, John C. Wootton Hit paper breakdown →	1993	1398
2	Comparative analyses of multi-species sequences from targeted genomic regions Nature ·James W. Thomas, Jeff Touchman, Robert W. Blakesley, Gerard G. Bouffard, Stephen M. Beckstrom‐Sternberg, Elliott H. Margulies, Mathieu Blanchette, Adam C. Siepel	2003	473
3	Sfold web server for statistical folding and rational design of nucleic acids Nucleic Acids Research ·Yong-Bin Ding, Charles E. Lawrence +1 other	2004	417
4	An expectation maximization (EM) algorithm for the identification and characterization of common sites in unaligned biopolymer sequences Proteins Structure Function and Bioinformatics ·Charles E. Lawrence, Andrew A. Reilly	1990	391
5	Human-mouse genome comparisons to locate regulatory sites Nature Genetics ·Wyeth W. Wasserman, Michael J. Palumbo, William A. Thompson, James Wildon Fickett, Charles E. Lawrence	2000	361
6	An empirical energy function for threading protein sequence through the folding motif Proteins Structure Function and Bioinformatics ·Stephen H. Bryant, Charles E. Lawrence	1993	331
7	Gibbs motif sampling: Detection of bacterial outer membrane protein repeats Protein Science ·Andrew F. Neuwald, Jun S. Liu, Charles E. Lawrence	1995	315
8	RNA secondary structure prediction by centroids in a Boltzmann weighted ensemble RNA ·Ding Ye, Chi Yu Chan, Charles E. Lawrence	2005	264
9	Algorithms for the optimal identification of segment neighborhoods Bulletin of Mathematical Biology ·Ivan E. Auger, Charles E. Lawrence	1989	237
10	Bayesian Models for Multiple Local Sequence Alignment and Gibbs Sampling Strategies Journal of the American Statistical Association ·Jun S. Liu, Andrew F. Neuwald, Charles E. Lawrence	1995	231
11	Natural selection of life history attributes: An analytical approach Theoretical Population Biology ·Howard M. Taylor, Robert S. Gourley, Charles E. Lawrence, Robert S. Kaplan	1974	205
12	Extracting protein alignment models from the sequence database Nucleic Acids Research ·Andrew F. Neuwald, Jun S. Liu, David J. Lipman, Charles E. Lawrence	1997	202
13	Chromatin remodeling in the aging genome of Drosophila Aging Cell ·Jason G. Wood, Sara Hillenmeyer, Charles E. Lawrence, Cheng-Yi Chang, Suzanne Hosier, Will Lightfoot, Eric Milan Mukherjee, Nan Jiang	2010	153
14	Extent and nature of contacts between protein molecules in crystal lattices and between subunits of protein oligomers Proteins Structure Function and Bioinformatics ·Swagata Dasgupta, Ganesh H. Iyer, Stephen H. Bryant, Charles E. Lawrence +1 other	1997	152
15	Effect of target secondary structure on RNAi efficiency RNA ·Yu Shao, Chi Yu Chan, Anil Maliyekkel, Charles E. Lawrence, Igor B. Roninson, Ding Ping Ye	2007	138
16	Toward a Cenozoic history of atmospheric CO 2 Science ·Bärbel Hönisch, Dana L. Royer, Daniel O. Breecker, P. J. Polissar, Gabriel J. Bowen, Michael J. Henehan, Ying Cui, Margret Steinthorsdottir Hit paper breakdown →	2023	138
17	Quantitative analysis of ribosome binding sites in E.coli Nucleic Acids Research ·Doug Barrick, Keith Villanueba, Rhonda Kalil, Thomas Dana Schneider, Charles E. Lawrence, Larry Gold, Gary D. Stormo +1 other	1994	125
18	Genome-wide analysis of A-to-I RNA editing by single-molecule sequencing in Drosophila Nature Structural & Molecular Biology ·Georges St. Laurent, Michael Tackett, Sergey Nechkin, Dmitry N. Shtokalo, Денис Антонец, Yiannis A. Savva, Rachel Maloney, Philipp Kapranov	2013	114
19	Bayesian inference on biopolymer models. Bioinformatics ·Jun S. Liu, Charles E. Lawrence	1999	111
20	Global profiling of Shewanella oneidensis MR-1: Expression of hypothetical genes and improved functional annotations Proceedings of the National Academy of Sciences ·Eugene Kolker, Alex F. Picone, Michael Y. Galperin, Margaret F. Romine, Roger Higdon, Kira S. Makarova, Natali Kolker, Gordon Anderson	2005	105

About Charles E. Lawrence

Charles E. Lawrence is a scholar working on Molecular Biology, Atmospheric Science, Statistics and Probability, Artificial Intelligence and Genetics, having authored 89 papers that have together received 7.5k indexed citations. Recurring topics across this work include Genomics and Phylogenetic Studies (31 papers), Genomics and Chromatin Dynamics (15 papers), Geology and Paleoclimatology Research (12 papers), Protein Structure and Dynamics (12 papers), RNA and protein synthesis mechanisms (9 papers), Statistical Methods and Inference (4 papers), RNA regulation and disease (4 papers) and Fractal and DNA sequence analysis (4 papers). The work is most often cited by research in Molecular Biology (5.1k citations), Aging (78 citations), Genetics (635 citations), Atmospheric Science (295 citations) and Artificial Intelligence (698 citations). Charles E. Lawrence has collaborated with scholars based in United States, Russia and China. Frequent co-authors include Jun S. Liu, Andrew F. Neuwald, Mark S. Boguski, Stephen F. Altschul, John C. Wootton, Stephen H. Bryant, Andrew A. Reilly, Yong-Bin Ding, Ivan E. Auger and Chi Yu Chan. Their work appears in journals such as Proteins Structure Function and Bioinformatics, Bioinformatics, Nucleic Acids Research, Journal of the American Statistical Association and Computer applications in the biosciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Charles E. Lawrence

Charles E. Lawrence's Hit Papers

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Fields of papers citing papers by Charles E. Lawrence

All Works

About Charles E. Lawrence

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