Barry A. Springer

5.3k citations

30 papers · 4.7k · 2 hit papers · h-index 25

Impact in

Cell Biology top 0.2%
- Hemoglobin structure and function
- Proteoglycans and glycosaminoglycans research
Molecular Biology top 2%
- Protein Structure and Dynamics
- Heme Oxygenase-1 and Carbon Monoxide
- Fibroblast Growth Factor Research
- Photosynthetic Processes and Mechanisms

Papers in

Cell Biology 16
- Hemoglobin structure and function 14
Molecular Biology 26
- Protein Structure and Dynamics 7
- Photosynthetic Processes and Mechanisms 4
- Porphyrin Metabolism and Disorders 4
- Fibroblast Growth Factor Research 3

Co-authors: Stephen G. Sligar (13 shared papers)John S. Olson (6 shared papers)Michael W. Pantoliano (5 shared papers)Karen D. Egeberg (6 shared papers)Ronald J. Rohlfs (5 shared papers)Antony J. Mathews (3 shared papers)Leo D. Thompson (2 shared papers)Theodore E. Carver (4 shared papers)
Journals: Journal of Biological Chemistry (10 papers)Biochemistry (4 papers)Bioorganic & Medicinal Chemistry Letters (2 papers)SLAS DISCOVERY (2 papers)Proceedings of the National Academy of Sciences (2 papers)
Partner nations: United States United Kingdom Italy

In The Last Decade

Barry A. Springer

30 papers receiving 4.6k citations

Barry A. Springer's Hit Papers

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High-Density Miniaturized Thermal Shift Assays as a General Strategy for Drug Discovery 2001 · 756 citations

What are hit papers?

Paper score: A paper's citations measured against the top-1% bar of its own field and year: the square root of citations ÷ bar, so 1 means right at the bar and 2 means four times its citations. The bar blends the citation counts that enter the top 1% of the paper's subfields in its year (weighted 89.5%), of those subfields over all years (0.5%) and of its year across all fields (10%); a subfield and year with fewer than 400 papers takes its year's bar. Papers from 2026 are not scored yet: in an unfinished year, when a paper appeared matters more than how it is cited.

Hit paper: A paper cited at least 1.5× the top-1% bar of its field and year: a paper score of at least √1.5.

2001 SLAS DISCOVERY
1994 Chemical Reviews

Peers

Countries citing papers authored by Barry A. Springer

Since Specialization

Citations

This map shows the geographic impact of Barry A. Springer's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Barry A. Springer with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Barry A. Springer more than expected).

Fields of papers citing papers by Barry A. Springer

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Barry A. Springer. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Barry A. Springer. The network helps show where Barry A. Springer may publish in the future.

Co-authors

The 25 scholars most cited alongside Barry A. Springer, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Barry A. Springer Line = papers co-authored together Barry A. Springer links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 30 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	High-Density Miniaturized Thermal Shift Assays as a General Strategy for Drug Discovery SLAS DISCOVERY ·Michael W. Pantoliano, Eugene C. Petrella, Joseph D. Kwasnoski, Victor S. Lobanov, James C. Myslik, E. R. Graf, Ted Carver, Eric D. Asel Hit paper breakdown →	2001	756
2	Mechanisms of Ligand Recognition in Myoglobin Chemical Reviews ·Barry A. Springer, Stephen G. Sligar, John S. Olson +1 other Hit paper breakdown →	1994	696
3	High-level expression of sperm whale myoglobin in Escherichia coli. Proceedings of the National Academy of Sciences ·Barry A. Springer, Stephen G. Sligar	1987	312
4	Discrimination between Oxygen and Carbon Monoxide and Inhibition of Autooxidation by Myoglobin Journal of Biological Chemistry ·Barry A. Springer, Karen D. Egeberg, Stephen G. Sligar, Ronald J. Rohlfs, Antony J. Mathews, John S. Olson	1989	271
5	The effects of amino acid substitution at position E7 (residue 64) on the kinetics of ligand binding to sperm whale myoglobin. Journal of Biological Chemistry ·Ronald J. Rohlfs, Antony J. Mathews, Theodore E. Carver, John S. Olson, Barry A. Springer, Karen D. Egeberg, Stephen G. Sligar	1990	271
6	The role of the distal histidine in myoglobin and haemoglobin Nature ·John S. Olson, Antony J. Mathews, Ronald J. Rohlfs, Barry A. Springer, Karen D. Egeberg, Stephen G. Sligar, Jeremy R. H. Tame, Jean‐Paul Renaud	1988	264
7	Energetic Characterization of the Basic Fibroblast Growth Factor-Heparin Interaction: Identification of the Heparin Binding Domain Biochemistry ·Leo D. Thompson, Michael W. Pantoliano, Barry A. Springer	1994	263
8	Multivalent Ligand-Receptor Binding Interactions in the Fibroblast Growth Factor System Produce a Cooperative Growth Factor and Heparin Mechanism for Receptor Dimerization Biochemistry ·Michael W. Pantoliano, Robert A. Horlick, Barry A. Springer, Drew E. Van Dyk, Timothy W. Tobery, Diana R. Wetmore, James D. Lear, Ara T. Nahapetian	1994	224
9	Resonance Raman investigations of site-directed mutants of myoglobin: effects of distal histidine replacement Biochemistry ·Dimitrios Morikis, Paul M. Champion, Barry A. Springer, Stephen G. Sligar	1989	187
10	Analysis of the kinetic barriers for ligand binding to sperm whale myoglobin using site-directed mutagenesis and laser photolysis techniques. Journal of Biological Chemistry ·Theodore E. Carver, Ronald J. Rohlfs, John S. Olson, Quentin Howieson Gibson, Richard S. Blackmore, Barry A. Springer, Stephen G. Sligar	1990	174
11	Functional reconstitution of β 2 -adrenergic receptors utilizing self-assembling Nanodisc technology BioTechniques ·Andrew J. Leitz, Timothy H. Bayburt, Alexander N. Barnakov, Barry A. Springer, Stephen G. Sligar	2006	174
12	Identification and concerted function of two receptor binding surfaces on basic fibroblast growth factor required for mitogenesis. Journal of Biological Chemistry ·Barry A. Springer, Michael W. Pantoliano, Frank A. Barbera, Paul L. Gunyuzlu, Leo D. Thompson, William F. Herblin, Stuart A. Rosenfeld, GlennW. Book	1994	128
13	Alteration of sperm whale myoglobin heme axial ligation by site-directed mutagenesis Biochemistry ·Karen D. Egeberg, Barry A. Springer, Susan A. Martinis, Stephen G. Sligar, Dimitrios Morikis, Paul M. Champion	1990	109
14	Crystal structure of myoglobin form a synthetic gene Proteins Structure Function and Bioinformatics ·Robert M. Arduini, Barry A. Springer, Stephen G. Sligar +1 other	1990	98
15	The role of Val68(E11) in ligand binding to sperm whale myoglobin. Site-directed mutagenesis of a synthetic gene. Journal of Biological Chemistry ·Karen D. Egeberg, Barry A. Springer, Stephen G. Sligar, Theodore E. Carver, Ronald J. Rohlfs, John S. Olson	1990	97
16	Transient spectroscopy of the reaction of cyanide with ferrous myoglobin. Effect of distal side residues. Journal of Biological Chemistry ·Andrea Bellelli, Giovanni Antonini, Maurizio Brunori, Barry A. Springer, Stephen G. Sligar	1990	90
17	Ligand binding to heme proteins: III. FTIR studies of His-E7 and Val-E11 mutants of carbonmonoxymyoglobin Biophysical Journal ·David Braunstein, K. R. Chu, Karen D. Egeberg, Hans Frauenfelder, Judith R. Mourant, Gerd Ulrich Nienhaus, Pál Ormos, Stephen G. Sligar	1993	88
18	4-Amino-6-arylamino-pyrimidine-5-carbaldehyde hydrazones as potent ErbB-2/EGFR dual kinase inhibitors Bioorganic & Medicinal Chemistry Letters ·Guozhang Xu, Marta C. Abad, Peter J. Connolly, Michael P. Neeper, Geoffrey T. Struble, Barry A. Springer, Stuart L. Emanuel, Niranjan B. Pandey	2008	82
19	Enhancing Recombinant Protein Quality and Yield by Protein Stability Profiling SLAS DISCOVERY ·Tara M. Mezzasalma, James K. Kranz, Winnie Chan, Geoffrey T. Struble, Céline Schalk‐Hihi, Ingrid C. Deckman, Barry A. Springer, Matthew J. Todd	2007	73
20	Resonance Raman studies of iron spin and axial coordination in distal pocket mutants of ferric myoglobin. Journal of Biological Chemistry ·Dimitrios Morikis, Paul M. Champion, Barry A. Springer, K D Egebey, Stephen G. Sligar	1990	63

About Barry A. Springer

Barry A. Springer is a scholar working on Cell Biology, Molecular Biology, Immunology and Allergy, Computational Theory and Mathematics and Oncology, having authored 30 papers that have together received 4.7k indexed citations. Recurring topics across this work include Hemoglobin structure and function (14 papers), Protein Structure and Dynamics (7 papers), Computational Drug Discovery Methods (4 papers), Photosynthetic Processes and Mechanisms (4 papers), Porphyrin Metabolism and Disorders (4 papers), Erythrocyte Function and Pathophysiology (4 papers), Fibroblast Growth Factor Research (3 papers) and Monoclonal and Polyclonal Antibodies Research (3 papers). The work is most often cited by research in Cell Biology (2.7k citations), Molecular Biology (3.4k citations), Biophysics (287 citations), Pediatrics, Perinatology and Child Health (534 citations) and Physiology (650 citations). Barry A. Springer has collaborated with scholars based in United States, United Kingdom and Italy. Frequent co-authors include Stephen G. Sligar, John S. Olson, Michael W. Pantoliano, Karen D. Egeberg, Ronald J. Rohlfs, Antony J. Mathews, Leo D. Thompson, Theodore E. Carver, Paul M. Champion and Dimitrios Morikis. Their work appears in journals such as Journal of Biological Chemistry, Biochemistry, Bioorganic & Medicinal Chemistry Letters, SLAS DISCOVERY and Proceedings of the National Academy of Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Barry A. Springer's Hit Papers

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All Works

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