Stuart L. Emanuel

2.5k citations

42 papers · 1.9k · h-index 24

Impact in

Organic Chemistry top 2%
- Synthesis and biological activity
- Synthesis and Biological Evaluation
- Synthesis and Characterization of Heterocyclic Compounds
- Click Chemistry and Applications
Oncology top 5%
- Cytokine Signaling Pathways and Interactions
- HER2/EGFR in Cancer Research

Papers in

Molecular Biology 22
- Angiogenesis and VEGF in Cancer 6
Oncology 20
- Cancer-related Molecular Pathways 8
- HER2/EGFR in Cancer Research 7

Co-authors: Peter J. Connolly (22 shared papers)Steven A. Middleton (19 shared papers)Angel R. Fuentes‐Pesquera (14 shared papers)Ronghui Lin (9 shared papers)Robert H. Gruninger (12 shared papers)Shenlin Huang (9 shared papers)Yanhua Lü (6 shared papers)Sidney Pestka (5 shared papers)
Journals: Bioorganic & Medicinal Chemistry Letters (15 papers)Journal of Medicinal Chemistry (8 papers)Journal of Biological Chemistry (3 papers)Cancer Research (2 papers)Genetic Analysis Biomolecular Engineering (2 papers)
Partner nations: United States Germany United Kingdom

In The Last Decade

Stuart L. Emanuel

42 papers receiving 1.8k citations

Peers

Countries citing papers authored by Stuart L. Emanuel

Since Specialization

Citations

This map shows the geographic impact of Stuart L. Emanuel's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Stuart L. Emanuel with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Stuart L. Emanuel more than expected).

Fields of papers citing papers by Stuart L. Emanuel

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Stuart L. Emanuel. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Stuart L. Emanuel. The network helps show where Stuart L. Emanuel may publish in the future.

Co-authors

The 25 scholars most cited alongside Stuart L. Emanuel, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Stuart L. Emanuel Line = papers co-authored together Stuart L. Emanuel links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 42 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Identification and sequence of an accessory factor required for activation of the human interferon γ receptor Cell ·Jaemog Soh, Robert Donnelly, Serguei V. Kotenko, Thomas M. Mariano, Jeffry R. Cook, Ning Wang, Stuart L. Emanuel, B Schwartz, Toru Miki, Sidney Pestka	1994	223
2	1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogues as Novel and Potent Anticancer Cyclin-Dependent Kinase Inhibitors: Synthesis and Evaluation of Biological Activities Journal of Medicinal Chemistry ·Ronghui Lin, Peter J. Connolly, Shenlin Huang, Steven K. Wetter, Yanhua Lü, William V. Murray, Stuart L. Emanuel, Robert H. Gruninger, Angel R. Fuentes‐Pesquera, Catherine A. Rugg, Steven A. Middleton, Linda K. Jolliffe	2005	112
3	Design, synthesis, and evaluation of 3,4-disubstituted pyrazole analogues as anti-tumor CDK inhibitors Bioorganic & Medicinal Chemistry Letters ·Ronghui Lin, George Chiu, Yang Yu, Peter J. Connolly, Shengjian Li, Yanhua Lü, Mary Adams, Angel R. Fuentes‐Pesquera, Stuart L. Emanuel, Lee M. Greenberger	2007	111
4	The In vitro and In vivo Effects of JNJ-7706621: A Dual Inhibitor of Cyclin-Dependent Kinases and Aurora Kinases Cancer Research ·Stuart L. Emanuel, Catherine A. Rugg, Robert H. Gruninger, Ronghui Lin, Angel R. Fuentes‐Pesquera, Peter J. Connolly, Steven K. Wetter, Beth Hollister, Walter W. Kruger, Cheryl Napier, Linda K. Jolliffe, Steven A. Middleton	2005	102
5	Synthesis of 3-(1H-benzimidazol-2-yl)-5-isoquinolin-4-ylpyrazolo[1,2-b]pyridine, a potent cyclin dependent kinase 1 (CDK1) inhibitor Bioorganic & Medicinal Chemistry Letters ·Shenlin Huang, Ronghui Lin, Yang Yu, Yanhua Lü, Peter J. Connolly, George Chiu, Shengjian Li, Stuart L. Emanuel, Steven A. Middleton	2006	101
6	EGF induces increased ligand binding affinity and dimerization of soluble epidermal growth factor (EGF) receptor extracellular domain. Journal of Biological Chemistry ·David R. Hurwitz, Stuart L. Emanuel, Margaret Nathan, Nava Sarver, A. Ullrich, Stephen Felder, Irit Lax, Joseph Schlessinger	1991	89
7	Discovery of anticancer agents of diverse natural origin Pure and Applied Chemistry ·A. Douglas Kinghorn, Esperanza J. Carcache de Blanco, Hee‐Byung Chai, Jimmy Orjala, Norman R. Farnsworth, Djaja D. Soejarto, Nicholas H. Oberlies, Mansukh C. Wani, David J. Kroll, Cedric J. Pearce, Steven M. Swanson, Robert A. Kramer, William C. Rose, Craig R. Fairchild, Gregory D. Vite, Stuart L. Emanuel, David Jarjoura, Frederick O. Cope	2009	86
8	4-Amino-6-arylamino-pyrimidine-5-carbaldehyde hydrazones as potent ErbB-2/EGFR dual kinase inhibitors Bioorganic & Medicinal Chemistry Letters ·Guozhang Xu, M.C. Abad, Peter J. Connolly, Michael P. Neeper, Geoffrey T. Struble, Barry A. Springer, Stuart L. Emanuel, Niranjan B. Pandey, Robert H. Gruninger, Mary Adams, Sandra Moreno-Mazza, Angel R. Fuentes‐Pesquera, Steven A. Middleton	2008	80
9	Synthesis and evaluation of pyrazolo[3,4-b]pyridine CDK1 inhibitors as anti-tumor agents Bioorganic & Medicinal Chemistry Letters ·Ronghui Lin, Peter J. Connolly, Yanhua Lü, George Chiu, Shengjian Li, Yang Yu, Shenlin Huang, Xun Li, Stuart L. Emanuel, Steven A. Middleton, Robert H. Gruninger, Mary Adams, Angel R. Fuentes‐Pesquera, Lee M. Greenberger	2007	75
10	Synthesis and Identification of [1,3,5]Triazine-pyridine Biheteroaryl as a Novel Series of Potent Cyclin-Dependent Kinase Inhibitors Journal of Medicinal Chemistry ·Gee‐Hong Kuo, A. DeAngelis, Stuart L. Emanuel, Aihua Wang, Yan Zhang, Peter J. Connolly, Xin Chen, Robert H. Gruninger, Catherine A. Rugg, Angel R. Fuentes‐Pesquera, Steven A. Middleton, Linda K. Jolliffe, William V. Murray	2005	72
11	Synthesis and Discovery of Macrocyclic Polyoxygenated Bis-7-azaindolylmaleimides as a Novel Series of Potent and Highly Selective Glycogen Synthase Kinase-3β Inhibitors Journal of Medicinal Chemistry ·Gee‐Hong Kuo, Catherine Prouty, A. DeAngelis, Lan Shen, David J. O’Neill, Chandra Shah, Peter J. Connolly, William V. Murray, (unknown), Peter Cheung, Lori Westover, Jun Xu, Richard A. Look, Keith T. Demarest, Stuart L. Emanuel, Steven A. Middleton, Linda K. Jolliffe, Mary Pat Beavers, Xin Chen	2003	72
12	The Discovery of Macrocyclic XIAP Antagonists from a DNA-Programmed Chemistry Library, and Their Optimization To Give Lead Compounds with in Vivo Antitumor Activity Journal of Medicinal Chemistry ·Benjamin A. Seigal, William H. Connors, Andrew W. Fraley, R. M. Borzilleri, Percy H. Carter, Stuart L. Emanuel, Joseph Fargnoli, Kyoung Kim, Ming Lei, Joseph G. Naglich, Matthew Pokross, Shana Posy, Henry Shen, Neha Surti, Randy Talbott, Yong Zhang, N.K. Terrett	2015	63
13	Novel Indolylindazolylmaleimides as Inhibitors of Protein Kinase C-β: Synthesis, Biological Activity, and Cardiovascular Safety Journal of Medicinal Chemistry ·Han‐Cheng Zhang, Claudia K. Derian, David F. McComsey, Kimberly B. White, Hong Ye, Leonard R. Hecker, Jian Li, (unknown), Diane R. Croll, Annette Eckardt, Charles E. Smith, Quan Li, Wai-man Cheung, (unknown), Stuart L. Emanuel, Keith T. Demarest, Patricia Andrade‐Gordon, Bruce P. Damiano, Bruce E. Maryanoff	2004	54
14	Macrocyclic bisindolylmaleimides as inhibitors of protein kinase C and glycogen synthase kinase-3 Bioorganic & Medicinal Chemistry Letters ·Han‐Cheng Zhang, Kimberly B. White, Hong Ye, David F. McComsey, Claudia K. Derian, (unknown), Patricia Andrade‐Gordon, Annette Eckardt, (unknown), Lori Westover, Jun Xu, Richard Look, Keith T. Demarest, Stuart L. Emanuel, Bruce E. Maryanoff	2003	53
15	Discovery of novel 4-amino-6-arylaminopyrimidine-5-carbaldehyde oximes as dual inhibitors of EGFR and ErbB-2 protein tyrosine kinases Bioorganic & Medicinal Chemistry Letters ·Guozhang Xu, Lily L. Searle, Terry V. Hughes, Amanda K. Beck, Peter J. Connolly, M.C. Abad, Michael P. Neeper, Geoffrey T. Struble, Barry A. Springer, Stuart L. Emanuel, Robert H. Gruninger, Niranjan B. Pandey, Mary Adams, Sandra Moreno-Mazza, Angel R. Fuentes‐Pesquera, Steven A. Middleton, Lee M. Greenberger	2008	49
16	Role of the ABCG2 drug transporter in the resistance and oral bioavailability of a potent cyclin-dependent kinase/Aurora kinase inhibitor Molecular Cancer Therapeutics ·Jennifer A. Seamon, Catherine A. Rugg, Stuart L. Emanuel, Anna Maria Calcagno, Suresh V. Ambudkar, Steven A. Middleton, Jeannene Butler, Virna Borowski, Lee M. Greenberger	2006	46
17	Synthesis and evaluation of N-acyl sulfonamides as potential prodrugs of cyclin-dependent kinase inhibitor JNJ-7706621 Bioorganic & Medicinal Chemistry Letters ·Shenlin Huang, Peter J. Connolly, Ronghui Lin, Stuart L. Emanuel, Steve A. Middleton	2006	41
18	4-Aryl-5-cyano-2-aminopyrimidines as VEGF-R2 inhibitors: Synthesis and biological evaluation Bioorganic & Medicinal Chemistry Letters ·Terry V. Hughes, Stuart L. Emanuel, Amanda K. Beck, Steven K. Wetter, Peter J. Connolly, Prabha Karnachi, Michael Reuman, Jabed Seraj, Angel R. Fuentes‐Pesquera, Robert H. Gruninger, Steven A. Middleton, Ronghui Lin, Jeremy Davis, David Moffat	2007	40
19	Sublocalization of the human interferon-gamma receptor accessory factor gene and characterization of accessory factor activity by yeast artificial chromosomal fragmentation. Journal of Biological Chemistry ·Jeffry R. Cook, Stuart L. Emanuel, Robert Donnelly, J. Soh, Thomas M. Mariano, B Schwartz, Sangkee Rhee, Sidney Pestka	1994	33
20	Synthesis and Structure−Activity Relationships of Pyrazine-Pyridine Biheteroaryls as Novel, Potent, and Selective Vascular Endothelial Growth Factor Receptor-2 Inhibitors Journal of Medicinal Chemistry ·Gee‐Hong Kuo, Catherine Prouty, Aihua Wang, Stuart L. Emanuel, A. DeAngelis, Yan Zhang, Fengbin Song, L. Dawson Beall, Peter J. Connolly, Prahba Karnachi, Xin Chen, Robert H. Gruninger, Jan L. Sechler, Angel R. Fuentes‐Pesquera, Steven A. Middleton, Linda K. Jolliffe, William V. Murray	2005	30

About Stuart L. Emanuel

Stuart L. Emanuel is a scholar working on Molecular Biology, Oncology, Organic Chemistry, Pulmonary and Respiratory Medicine and Toxicology, having authored 42 papers that have together received 1.9k indexed citations. Recurring topics across this work include Cancer-related Molecular Pathways (8 papers), HER2/EGFR in Cancer Research (7 papers), Microtubule and mitosis dynamics (6 papers), Angiogenesis and VEGF in Cancer (6 papers), Bioactive Compounds and Antitumor Agents (6 papers), Monoclonal and Polyclonal Antibodies Research (5 papers), Click Chemistry and Applications (4 papers) and Advanced Breast Cancer Therapies (4 papers). The work is most often cited by research in Organic Chemistry (749 citations), Oncology (532 citations), Toxicology (67 citations), Immunology (231 citations) and Molecular Biology (745 citations). Stuart L. Emanuel has collaborated with scholars based in United States, Germany and United Kingdom. Frequent co-authors include Peter J. Connolly, Steven A. Middleton, Angel R. Fuentes‐Pesquera, Ronghui Lin, Robert H. Gruninger, Shenlin Huang, Yanhua Lü, Sidney Pestka, Mary Adams and Catherine A. Rugg. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Journal of Medicinal Chemistry, Journal of Biological Chemistry, Cancer Research and Genetic Analysis Biomolecular Engineering.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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