Yiling Lu

127.2k citations

213 papers · 15.8k · 3 hit papers · h-index 64

Impact in

Cancer Research top 0.2%
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
Molecular Biology top 0.2%
- PI3K/AKT/mTOR signaling in cancer
- Sphingolipid Metabolism and Signaling
- Protein Kinase Regulation and GTPase Signaling
- RNA modifications and cancer

Papers in

Molecular Biology 149
- PI3K/AKT/mTOR signaling in cancer 39
- Advanced Biosensing Techniques and Applications 26
- Protein Kinase Regulation and GTPase Signaling 13
- Sphingolipid Metabolism and Signaling 11
Oncology 33

Co-authors: Gordon B. Mills (157 shared papers)Bryan T. Hennessy (21 shared papers)Prahlad T. Ram (9 shared papers)Debra L. Smith (3 shared papers)Xianjun Fang (16 shared papers)Robert C. Bast (11 shared papers)Shuangxing Yu (23 shared papers)James R. Woodgett (2 shared papers)
Journals: Cancer Research (26 papers)Oncogene (9 papers)Journal of Biological Chemistry (9 papers)Cancer Cell (8 papers)PLoS ONE (7 papers)
Partner nations: United States China United Kingdom

In The Last Decade

Yiling Lu

207 papers receiving 15.6k citations

Yiling Lu's Hit Papers

align trajectories log scale

Exploiting the PI3K/AKT Pathway for Cancer Drug Discovery 2005 · 1.8k citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2005 Nature Reviews Drug Discovery
2000 Proceedings of the National Academy of Sciences
1999 Nature Genetics

Peers

Countries citing papers authored by Yiling Lu

Since Specialization

Citations

This map shows the geographic impact of Yiling Lu's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Yiling Lu with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Yiling Lu more than expected).

Fields of papers citing papers by Yiling Lu

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Yiling Lu. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Yiling Lu. The network helps show where Yiling Lu may publish in the future.

Co-authors

The 25 scholars most cited alongside Yiling Lu, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Yiling Lu Line = papers co-authored together Yiling Lu links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 213 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Exploiting the PI3K/AKT Pathway for Cancer Drug Discovery Nature Reviews Drug Discovery ·Bryan T. Hennessy, Debra L. Smith, Prahlad T. Ram, Yiling Lu, Gordon B. Mills Hit paper breakdown →	2005	1764
2	PIK3CA is implicated as an oncogene in ovarian cancer Nature Genetics ·Laleh Shayesteh, Yiling Lu, Wen-Lin Kuo, R. A. Baldocchi, Tony E. Godfrey, Colin C. Collins, Daniel Pinkel, Bethan Powell, Gordon B. Mills, Joe W. Gray Hit paper breakdown →	1999	926
3	Phosphorylation and inactivation of glycogen synthase kinase 3 by protein kinase A Proceedings of the National Academy of Sciences ·Xianjun Fang, Shuang Yu, Yiling Lu, Robert C. Bast, James R. Woodgett, Gordon B. Mills Hit paper breakdown →	2000	693
4	Reverse phase protein array: validation of a novel proteomic technology and utility for analysis of primary leukemia specimens and hematopoietic stem cells Molecular Cancer Therapeutics ·Raoul Tibes, Yihua Qiu, Yiling Lu, Bryan T. Hennessy, Michael Andreeff, Gordon B. Mills, Steven M. Kornblau	2006	487
5	Validation of an anti-sphingosine-1-phosphate antibody as a potential therapeutic in reducing growth, invasion, and angiogenesis in multiple tumor lineages Cancer Cell ·Barbara Visentin, John Vekich, Bradley J. Sibbald, Amy L. Cavalli, Kelli Moreno, Rosalía Matteo, William Garland, Yiling Lu, Shuangxing Yu, Hassan Hall, Vikas Kundra, Gordon B. Mills, Roger A. Sabbadini	2006	381
6	The tumor suppressor gene ARHI regulates autophagy and tumor dormancy in human ovarian cancer cells Journal of Clinical Investigation ·Zhen Lü, Robert Z. Luo, Yiling Lu, Xuhui Zhang, Qinghua Yu, Shilpi Khare, Seiji Kondo, Yasuko Kondo, Yinhua Yu, Gordon B. Mills, Warren S.‐L. Liao, Robert C. Bast	2008	380
7	A module of negative feedback regulators defines growth factor signaling Nature Genetics ·Ido Amit, Ami Citri, Tal Shay, Yiling Lu, Menachem Katz, Fan Zhang, Gabi Tarcic, Doris R. Siwak, John Lahad, Jasmine Jacob‐Hirsch, Ninette Amariglio, Nora Vaisman, Eran Segal, Gideon Rechavi, Uri Alon, Gordon B. Mills, Eytan Domany, Yosef Yarden	2007	362
8	High Frequency of PIK3R1 and PIK3R2 Mutations in Endometrial Cancer Elucidates a Novel Mechanism for Regulation of PTEN Protein Stability Cancer Discovery ·Lydia W.T. Cheung, Bryan T. Hennessy, Jie Li, Shuangxing Yu, Andrea P. Myers, Bojana Djordjevic, Yiling Lu, Katherine Stemke‐Hale, Mary D. Dyer, Fan Zhang, Zhenlin Ju, Lewis C. Cantley, Steven E. Scherer, Han Liang, Karen H. Lu, Russell R. Broaddus, Gordon B. Mills	2011	360
9	Inhibition of phosphatidylinositol 3'-kinase increases efficacy of paclitaxel in in vitro and in vivo ovarian cancer models. PubMed ·Limin Hu, Judith Hofmann, Yiling Lu, Gordon B. Mills, Robert B. Jaffe	2002	311
10	Expression of Autotaxin and Lysophosphatidic Acid Receptors Increases Mammary Tumorigenesis, Invasion, and Metastases Cancer Cell ·Shuying Liu, Makiko Umezu‐Goto, Mandi M. Murph, Yiling Lu, Wenbin Liu, Fan Zhang, Shuangxing Yu, L. Clifton Stephens, Xiaojiang Cui, George Murrow, Kevin R. Coombes, William J. Muller, Mien‐Chie Hung, Charles M. Perou, Adrian V. Lee, Xianjun Fang, Gordon B. Mills	2009	310
11	The PTEN/MMAC1/TEP tumor suppressor gene decreases cell growth and induces apoptosis and anoikis in breast cancer cells Oncogene ·Yiling Lu, Yue-Zhen Lin, Ruth LaPushin, Bruce D. Cuevas, Xianjun Fang, Shuang Yu, Michael A. Davies, Humera Khan, Tatsuro Furui, Muling Mao, Ralph Zinner, Mien‐Chie Hung, Peter A. Steck, Kathy Siminovitch, Gordon B. Mills	1999	262
12	A Vascular Targeted Pan Phosphoinositide 3-Kinase Inhibitor Prodrug, SF1126, with Antitumor and Antiangiogenic Activity Cancer Research ·Joseph R. Garlich, Pradip De, Nandini Dey, Jing Su, Xiaodong Peng, Antoinette Miller, Ravoori Murali, Yiling Lu, Gordon B. Mills, Vikas Kundra, H-K. Shu, Qiong Peng, Donald L. Durden	2008	232
13	Use of Reverse Phase Protein Microarrays and Reference Standard Development for Molecular Network Analysis of Metastatic Ovarian Carcinoma Molecular & Cellular Proteomics ·Katherine M. Sheehan, Valerie Calvert, Elaine W. Kay, Yiling Lu, David A. Fishman, Virginia Espina, Joy Aquino, Runa Speer, Robyn P. Araujo, Gordon B. Mills, Lance A. Liotta, Emanuel F. Petricoin, Julia Wulfkuhle	2005	228
14	Src Family Protein-tyrosine Kinases Alter the Function of PTEN to Regulate Phosphatidylinositol 3-Kinase/AKT Cascades Journal of Biological Chemistry ·Yiling Lu, Qinghua Yu, Jue Hui Liu, Jinyi Zhang, Hongwei Wang, Dimpy Koul, John S. McMurray, Xianjun Fang, W.K. Alfred Yung, Kathy Siminovitch, Gordon B. Mills	2003	220
15	Tyrosine Phosphorylation of p85 Relieves Its Inhibitory Activity on Phosphatidylinositol 3-Kinase Journal of Biological Chemistry ·Bruce D. Cuevas, Yiling Lu, Muling Mao, Jinyi Zhang, Ruth LaPushin, Kathy Siminovitch, Gordon B. Mills	2001	215
16	BRD4 Inhibition Is Synthetic Lethal with PARP Inhibitors through the Induction of Homologous Recombination Deficiency Cancer Cell ·Chaoyang Sun, (unknown), Yong Fang, Jian Chen, Kang Jin Jeong, Xiaohua Chen, Christopher P. Vellano, Zhenlin Ju, Wei Zhao, Dong Zhang, Yiling Lu, Funda Meric‐Bernstam, Timothy A. Yap, Maureen M. Hattersley, Mark J. O’Connor, Huawei Chen, Stephen E. Fawell, Shiaw‐Yih Lin, Guang Peng, Gordon B. Mills	2018	211
17	Verteporfin inhibits YAP function through up-regulating 14-3-3σ sequestering YAP in the cytoplasm. PubMed ·Chao Wang, Xiao‐Yong Zhu, Weiwei Feng, Yinhua Yu, Kangjin Jeong, Wei Guo, Yiling Lu, Gordon B. Mills	2016	208
18	Dual Inhibition of Tumor Energy Pathway by 2-Deoxyglucose and Metformin Is Effective against a Broad Spectrum of Preclinical Cancer Models Molecular Cancer Therapeutics ·Jae‐Ho Cheong, Eun Sung Park, Jiyong Liang, Jennifer B. Dennison, Dimitra Tsavachidou, Catherine Nguyen-Charles, Kwai Wa Cheng, Hassan Hall, Dong Zhang, Yiling Lu, Murali K. Ravoori, Vikas Kundra, Jaffer A. Ajani, Ju‐Seog Lee, Waun Ki Hong, Gordon B. Mills	2011	206
19	miR-145 participates with TP53 in a death-promoting regulatory loop and targets estrogen receptor-α in human breast cancer cells Cell Death and Differentiation ·Riccardo Spizzo, Milena S. Nicoloso, Laura Lupini, Yiling Lu, Julie A Fogarty, Simona Rossi, Barbara Zagatti, Muller Fabbri, Angelo Veronese, X Liu, Ramana V. Davuluri, Carlo M. Croce, Gordon B. Mills, Massimo Negrini, George A. Calin	2009	205
20	Insulin-Like Growth Factor-I Inhibits Progesterone Receptor Expression in Breast Cancer Cells via the Phosphatidylinositol 3-Kinase/Akt/Mammalian Target of Rapamycin Pathway: Progesterone Receptor as a Potential Indicator of Growth Factor Activity in Breast Cancer Molecular Endocrinology ·Xiaojiang Cui, Ping Zhang, Wanleng Deng, Steffi Oesterreich, Yiling Lu, Gordon B. Mills, Adrian V. Lee	2003	196

About Yiling Lu

Yiling Lu is a scholar working on Molecular Biology, Oncology, Cancer Research, Cell Biology and Spectroscopy, having authored 213 papers that have together received 15.8k indexed citations. Recurring topics across this work include PI3K/AKT/mTOR signaling in cancer (39 papers), Advanced Biosensing Techniques and Applications (26 papers), Advanced Proteomics Techniques and Applications (15 papers), Protein Kinase Regulation and GTPase Signaling (13 papers), Monoclonal and Polyclonal Antibodies Research (12 papers), Sphingolipid Metabolism and Signaling (11 papers), Cancer Genomics and Diagnostics (11 papers) and Cancer Mechanisms and Therapy (11 papers). The work is most often cited by research in Cancer Research (2.6k citations), Molecular Biology (10.7k citations), Oncology (3.0k citations), Cell Biology (1.7k citations) and Reproductive Medicine (569 citations). Yiling Lu has collaborated with scholars based in United States, China and United Kingdom. Frequent co-authors include Gordon B. Mills, Bryan T. Hennessy, Prahlad T. Ram, Debra L. Smith, Xianjun Fang, Robert C. Bast, Shuangxing Yu, James R. Woodgett, Ruth LaPushin and Joe W. Gray. Their work appears in journals such as Cancer Research, Oncogene, Journal of Biological Chemistry, Cancer Cell and PLoS ONE.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Yiling Lu's Hit Papers

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