Peter John Ratcliffe

78.9k citations
424 papers · 65.9k · 18 hit papers · h-index 117

Impact in

  • Cancer Research top 0.01%
    • Cancer, Hypoxia, and Metabolism
    • Mitochondrial Function and Pathology
    • Epigenetics and DNA Methylation
    • RNA modifications and cancer
    • Angiogenesis and VEGF in Cancer
    • Ubiquitin and proteasome pathways

Papers in

Peter John Ratcliffe

411 papers receiving 64.1k citations

Peter John Ratcliffe's Hit Papers

Dynamic regulatory network controlling TH17 cell differentiation 2013 · 556 citations
5560+8+17Years since publication10002.0k3.0k4.0k

Peers

Peter John Ratcliffe
Comparison fields: 5 of 209
  • Cancer Research 37.5k
  • Molecular Biology 35.7k
  • Biochemistry 3.0k
  • Genetics 9.9k
  • Hematology 3.7k
Replace Patrick Henry Maxwell with:
Patrick Henry Maxwell United Kingdom
Gregg L. Semenza United States
William G. Kaelin United States
Christopher William Pugh United Kingdom
Chi V. Dang United States
Matthew G. Vander Heiden United States
Adrian L. Harris United Kingdom
Pier Paolo Pandolfi United States
Stephen B. Baylin United States
Curtis C. Harris United States
Peter John Ratcliffe relative to Patrick Henry Maxwell United Kingdom Patrick Henry Maxwell's profile →
Citations per field
00.5×1.5×1.8×
Patrick Henry Maxwell · 1×
Citations per year

Countries citing papers authored by Peter John Ratcliffe

Since Specialization
Citations

This map shows the geographic impact of Peter John Ratcliffe's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Peter John Ratcliffe with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Peter John Ratcliffe more than expected).

Fields of papers citing papers by Peter John Ratcliffe

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Peter John Ratcliffe. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Peter John Ratcliffe. The network helps show where Peter John Ratcliffe may publish in the future.

Co-authors

The 25 scholars most cited alongside Peter John Ratcliffe, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Peter John Ratcliffe Line = papers co-authored together Peter John Ratcliffe links everyone, so they are left out of the graph.

All Works

20 of 20 papers shown

Showing the 20 most-cited of 424 papers — load more, or switch the sort, to bring in the rest.

#Work
1
Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O 2 -Regulated Prolyl Hydroxylation
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20014802
2
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
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19994413
3
C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation
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20012880
4
Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
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20082679
5
Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
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19982223
6
Regulation of angiogenesis by hypoxia: role of the HIF system
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20032094
7
Oxygen sensing by HIF hydroxylases
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20041763
8
The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages
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20001127
9
Hypoxia-inducible expression of tumor-associated carbonic anhydrases.
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20001126
10
Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth
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1997954
11
Differential Function of the Prolyl Hydroxylases PHD1, PHD2, and PHD3 in the Regulation of Hypoxia-inducible Factor
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2004933
12
Hypoxia Inducible Factor-α Binding and Ubiquitylation by the von Hippel-Lindau Tumor Suppressor Protein
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2000910
13
Independent function of two destruction domains in hypoxia‐inducible factor‐α chains activated by prolyl hydroxylation
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2001883
14
The oncometabolite 2‐hydroxyglutarate inhibits histone lysine demethylases
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2011858
15
Contrasting Properties of Hypoxia-Inducible Factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-Associated Renal Cell Carcinoma
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2005826
16
HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: Novel role of fumarate in regulation of HIF stability
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2005795
17
Heterozygous Deficiency of PHD2 Restores Tumor Oxygenation and Inhibits Metastasis via Endothelial Normalization
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2009674
18 2002649
19
HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors.
2001630
20 2002623

About Peter John Ratcliffe

Peter John Ratcliffe is a scholar working on Cancer Research, Genetics, Molecular Biology, Physiology and Hematology, having authored 424 papers that have together received 65.9k indexed citations. Recurring topics across this work include Cancer, Hypoxia, and Metabolism (217 papers), High Altitude and Hypoxia (71 papers), RNA modifications and cancer (42 papers), Mitochondrial Function and Pathology (40 papers), Epigenetics and DNA Methylation (40 papers), Adipose Tissue and Metabolism (35 papers), Erythropoietin and Anemia Treatment (33 papers) and Metabolomics and Mass Spectrometry Studies (17 papers). The work is most often cited by research in Cancer Research (37.5k citations), Molecular Biology (35.7k citations), Biochemistry (3.0k citations), Genetics (9.9k citations) and Hematology (3.7k citations). Peter John Ratcliffe has collaborated with scholars based in United Kingdom, United States and Germany. Frequent co-authors include Christopher William Pugh, Patrick Henry Maxwell, Christopher John Schofield, William G. Kaelin, Adrian L. Harris, David Robert Mole, Jonathan Gleadle, Ya‐Min Tian, Charles C. Wykoff and Norma Masson. Their work appears in journals such as Journal of Biological Chemistry, Kidney International, Proceedings of the National Academy of Sciences, Blood and Journal of Clinical Investigation.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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