Paul Eggleton

6.8k citations

122 papers · 5.9k · 1 hit paper · h-index 44

Impact in

Immunology top 0.5%
- Complement system in diseases
- Immune Response and Inflammation
- Biomarkers in Disease Mechanisms
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Rheumatology top 1%
- Rheumatoid Arthritis Research and Therapies
- Systemic Lupus Erythematosus Research

Papers in

Immunology 50
- Complement system in diseases 19
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms 14
- Biomarkers in Disease Mechanisms 6
- Immune Response and Inflammation 5
Rheumatology 33
- Systemic Lupus Erythematosus Research 19
- Rheumatoid Arthritis Research and Therapies 14

Co-authors: Kenneth B. M. Reid (11 shared papers)Marek Michalak (14 shared papers)K.B.M. Reid (9 shared papers)Uday Kishore (8 shared papers)Paul Graham Winyard (19 shared papers)Joanne E. Murphy-Ullrich (3 shared papers)Edwin Bremer (13 shared papers)Wilhelm Schwaeble (3 shared papers)
Journals: Clinical & Experimental Immunology (7 papers)International Journal of Molecular Sciences (4 papers)Biochemical Society Transactions (4 papers)Journal of Biological Chemistry (4 papers)Infection and Immunity (4 papers)
Partner nations: United Kingdom United States Canada

In The Last Decade

Paul Eggleton

120 papers receiving 5.7k citations

Paul Eggleton's Hit Papers

align trajectories log scale

A second serine protease associated with mannan-binding lectin that activates complement 1997 · 721 citations

What are hit papers?

Paper score: A paper's citations measured against the top-1% bar of its own field and year: the square root of citations ÷ bar, so 1 means right at the bar and 2 means four times its citations. The bar blends the citation counts that enter the top 1% of the paper's subfields in its year (weighted 89.5%), of those subfields over all years (0.5%) and of its year across all fields (10%); a subfield and year with fewer than 400 papers takes its year's bar. Papers from 2026 are not scored yet: in an unfinished year, when a paper appeared matters more than how it is cited.

Hit paper: A paper cited at least 1.5× the top-1% bar of its field and year: a paper score of at least √1.5.

1997 Nature

Peers

Countries citing papers authored by Paul Eggleton

Since Specialization

Citations

This map shows the geographic impact of Paul Eggleton's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Paul Eggleton with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Paul Eggleton more than expected).

Fields of papers citing papers by Paul Eggleton

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Paul Eggleton. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Paul Eggleton. The network helps show where Paul Eggleton may publish in the future.

Co-authors

The 25 scholars most cited alongside Paul Eggleton, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Paul Eggleton Line = papers co-authored together Paul Eggleton links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 122 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	A second serine protease associated with mannan-binding lectin that activates complement Nature ·Steffen Thiel, Thomas Vorup‐Jensen, Cordula M. Stover, Wilhelm Schwaeble, Steen Broch Laursen, Knud Poulsen, Paul Eggleton, Søren Hansen Hit paper breakdown →	1997	721
2	Calreticulin: non‐endoplasmic reticulum functions in physiology and disease The FASEB Journal ·Leslie I. Gold, Paul Eggleton, Mariya T. Sweetwyne, Lauren B. Van Duyn, Matthew R. Greives, Sara‐Megumi Naylor, Marek Michalak, Joanne E. Murphy-Ullrich	2009	338
3	Evidence for a protective role of pulmonary surfactant protein D (SP-D) against influenza A viruses. Journal of Clinical Investigation ·Kevan L. Hartshorn, Erika C. Crouch, Mitchell R. White, Paul Eggleton, Alfred I. Tauber, Donald S. Chang, K Sastry	1994	280
4	Binding of pulmonary surfactant proteins A and D to Aspergillus fumigatus conidia enhances phagocytosis and killing by human neutrophils and alveolar macrophages Infection and Immunity ·Taruna Madan, Paul Eggleton, Uday Kishore, S S Aggrawal, P. Usha Sarma, K.B.M. Reid +1 other	1997	254
5	Thrombospondin Mediates Focal Adhesion Disassembly through Interactions with Cell Surface Calreticulin Journal of Biological Chemistry ·Silvia M. Goicoechea, Anthony Wayne Orr, Manuel Antonio Pallero, Paul Eggleton, Joanne E. Murphy-Ullrich	2000	149
6	Lung surfactant proteins A and D can inhibit specific IgE binding to the allergens of Aspergillus fumigatus and block allergen-induced histamine release from human basophils Clinical & Experimental Immunology ·Taruna Madan, Uday Kishore, Ashok Kumar Shah, Paul Eggleton, Jiu‐Yao Wang, S S Aggrawal, P. Usha Sarma, K.B.M. Reid +1 other	1997	137
7	Properdin, a positive regulator of complement activation, is released from secondary granules of stimulated peripheral blood neutrophils The Journal of Immunology ·Urs Wirthmueller, Béatrice Dewald, Marcus Thelen, Cordula M. Stover, Keith Whaley, Paul Eggleton, K.B.M. Reid, Wilhelm Schwaeble +2 others	1997	128
8	Mechanisms of Translocation of ER Chaperones to the Cell Surface and Immunomodulatory Roles in Cancer and Autoimmunity Frontiers in Oncology ·Valerie R. Wiersma, Marek Michalak, Trefa Mohammed Abdullah, Edwin Bremer, Paul Eggleton	2015	123
9	Impaired recognition of apoptotic neutrophils by the C1q/calreticulin and CD91 pathway in systemic lupus erythematosus Arthritis & Rheumatism ·Wendy Roake, Simon Brown, Philip J. Young, Haley Bharat Naik, Paul Wordsworth, David Alan Isenberg, Kenneth B. M. Reid, Paul Eggleton +1 other	2006	120
10	The innate immune component ficolin 3 (Hakata antigen) mediates the clearance of late apoptotic cells Arthritis & Rheumatism ·Christian Honoré, Tina Hummelshøj, Bjarke Endel Hansen, HANS OLE MADSEN, Paul Eggleton, Peter Garred	2007	113
11	The Conformation of Calreticulin Is Influenced by the Endoplasmic Reticulum Luminal Environment Journal of Biological Chemistry ·Elaine F. Corbett, Karolina M. Michalak, Kim Oikawa, Steven Johnson, Iain Donald Campbell, Paul Eggleton, Cyril M. Kay, Marek Michalak	2000	110
12	A calreticulin‐like molecule from the human hookworm Necator americanus interacts with C1q and the cytoplasmic signalling domains of some integrins Parasite Immunology ·Grit Kasper, Alan Brown, Matthias Eberl, Laurent Vallar, Nelly Kieffer, Colin Berry, Karen Girdwood, Paul Eggleton	2001	106
13	The Anti-adhesive Activity of Thrombospondin Is Mediated by the N-terminal Domain of Cell Surface Calreticulin Journal of Biological Chemistry ·Silvia M. Goicoechea, Manuel Antonio Pallero, Paul Eggleton, Marek Michalak, Joanne E. Murphy-Ullrich	2002	103
14	A Mechanism of Release of Calreticulin from Cells During Apoptosis Journal of Molecular Biology ·Joanna M. Tarr, Philip J. Young, Robert Morse, Debra J. Shaw, Richard C. Haigh, Peter G. Petrov, Steven Johnson, Paul Graham Winyard	2010	95
15	Measurement and meaning of markers of reactive species of oxygen, nitrogen and sulfur in healthy human subjects and patients with inflammatory joint disease Biochemical Society Transactions ·Paul Graham Winyard, Brent James Ryan, Paul Eggleton, Ahuva Nissim, Emma Taylor, Maria Letizia Lo Faro, Torsten Burkholz, Katalin Szabó-Taylor	2011	95
16	Calreticulin Is Released from Activated Neutrophils and Binds to C1q and Mannan-Binding Protein Clinical Immunology and Immunopathology ·Paul Eggleton, T S Lieu, Eugene G. Zappi, K Sastry, John P. Coburn, Ken Scott Zaner, Richard Dennis Sontheimer, J D Capra	1994	93
17	Rapid method for the isolation of neutrophils in high yield without the use of dextran or density gradient polymers Journal of Immunological Methods ·Paul Eggleton, R.A. Gargan, Derek R. Fisher	1989	91
18	The lung in ACPA-positive rheumatoid arthritis: an initiating site of injury? Lara D. Veeken ·Elizabeth S Perry, Clive Anthony Kelly, Paul Eggleton, Anthony De Soyza, David G. Hutchinson	2014	86
19	C1q receptors Clinical & Experimental Immunology ·Paul Eggleton, Andrea J. Tenner, K.B.M. Reid	2000	80
20	Consequence of neo-antigenicity of the 'altered self' Lara D. Veeken ·Paul Eggleton, Richard C. Haigh, Paul Graham Winyard	2008	75

About Paul Eggleton

Paul Eggleton is a scholar working on Immunology, Rheumatology, Cell Biology, Molecular Biology and Rehabilitation, having authored 122 papers that have together received 5.9k indexed citations. Recurring topics across this work include Complement system in diseases (19 papers), Systemic Lupus Erythematosus Research (19 papers), Endoplasmic Reticulum Stress and Disease (14 papers), Rheumatoid Arthritis Research and Therapies (14 papers), Neutrophil, Myeloperoxidase and Oxidative Mechanisms (14 papers), Heat shock proteins research (8 papers), Biomarkers in Disease Mechanisms (6 papers) and Immune Response and Inflammation (5 papers). The work is most often cited by research in Immunology (2.3k citations), Rheumatology (602 citations), Cell Biology (533 citations), Immunology and Allergy (135 citations) and Molecular Biology (1.1k citations). Paul Eggleton has collaborated with scholars based in United Kingdom, United States and Canada. Frequent co-authors include Kenneth B. M. Reid, Marek Michalak, K.B.M. Reid, Uday Kishore, Paul Graham Winyard, Joanne E. Murphy-Ullrich, Edwin Bremer, Wilhelm Schwaeble, Cordula M. Stover and K Sastry. Their work appears in journals such as Clinical & Experimental Immunology, International Journal of Molecular Sciences, Biochemical Society Transactions, Journal of Biological Chemistry and Infection and Immunity.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Paul Eggleton's Hit Papers

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