Patrick W. Vincent

7.7k citations
62 papers · 2.6k · 1 hit paper · h-index 24

Impact in

  • Oncology top 5%
    • HER2/EGFR in Cancer Research
    • Colorectal Cancer Treatments and Studies
  • Molecular Biology top 5%
    • Cancer therapeutics and mechanisms
    • PI3K/AKT/mTOR signaling in cancer

Papers in

  • Molecular Biology 27
    • Melanoma and MAPK Pathways 7
    • PI3K/AKT/mTOR signaling in cancer 7
  • Oncology 14
    • HER2/EGFR in Cancer Research 10
Co-authors
James M. Nelson (6 shared papers)H. D. Hollis Showalter (9 shared papers)William L. Elliott (12 shared papers)William A. Denny (8 shared papers)Claude Cassagne (6 shared papers)David W. Fry (8 shared papers)Patrick Moreau (6 shared papers)Gordon W. Rewcastle (4 shared papers)
Journals
Journal of Medicinal Chemistry (9 papers)Cancer Research (6 papers)Molecular Cancer Therapeutics (5 papers)Bioorganic & Medicinal Chemistry Letters (2 papers)Biology of Reproduction (2 papers)
Partner nations
United StatesCanadaFrance

In The Last Decade

Patrick W. Vincent

60 papers receiving 2.6k citations

Patrick W. Vincent's Hit Papers

PF00299804, an Irreversible Pan-ERBB Inhibitor, Is Effective in Lung Cancer Models with EGFR and ERBB2 Mutations that Are Resistant to Gefitinib 2007 · 598 citations
5980+6+12Years since publication100200300400500
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

  • it has ≥500 total citations;
  • it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
  • it reaches the top citation threshold in at least one of its specific research topics.
  1. 2007 Cancer Research

Peers

Patrick W. Vincent
Comparison fields: 5 of 122
  • Oncology 886
  • Molecular Biology 1.4k
  • Pulmonary and Respiratory Medicine 660
  • Organic Chemistry 569
  • Biochemistry 124
Replace Xuhong Cheng with:
Xuhong Cheng United States
Hong Wu China
Min H. Kang United States
Eric H. Holmes United States
Marc Navre United States
Linda K. Jolliffe United States
Kenji Sugita Japan
Sharon Gowan United Kingdom
Kenji Ishitsuka Japan
Sridhar K. Rabindran United States
Patrick W. Vincent relative to Xuhong Cheng United States Xuhong Cheng's profile →
Citations per field
00.5×2×4×6.1×
Xuhong Cheng · 1×
Citations per year

Countries citing papers authored by Patrick W. Vincent

Since Specialization
Citations

This map shows the geographic impact of Patrick W. Vincent's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Patrick W. Vincent with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Patrick W. Vincent more than expected).

Fields of papers citing papers by Patrick W. Vincent

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Patrick W. Vincent. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Patrick W. Vincent. The network helps show where Patrick W. Vincent may publish in the future.

Co-authors

The 25 scholars most cited alongside Patrick W. Vincent, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Patrick W. Vincent Line = papers co-authored together Patrick W. Vincent links everyone, so they are left out of the graph.

All Works

20 of 20 papers shown

Showing the 20 most-cited of 62 papers — load more, or switch the sort, to bring in the rest.

#Work
1
PF00299804, an Irreversible Pan-ERBB Inhibitor, Is Effective in Lung Cancer Models with EGFR and ERBB2 Mutations that Are Resistant to Gefitinib
Cancer Research ·Jeffrey A. Engelman, Kreshnik Zejnullahu, Christopher-Michael Gale, Eugene Lifshits, Andrea J. Gonzales, Takeshi Shimamura, Feng Zhao, Patrick W. Vincent, George N. Naumov, James E. Bradner, Irene W. Althaus, Leena Gandhi, Geoffrey I. Shapiro, James M. Nelson, John V. Heymach, Matthew Meyerson, Kwok‐Kin Wong, Pasi A. Jänne
Hit paper breakdown →		2007598
2
Tyrosine Kinase Inhibitors. 17. Irreversible Inhibitors of the Epidermal Growth Factor Receptor:  4-(Phenylamino)quinazoline- and 4-(Phenylamino)pyrido[3,2-d]pyrimidine-6-acrylamides Bearing Additional Solubilizing Functions
Journal of Medicinal Chemistry ·Jeff B. Smaill, Gordon W. Rewcastle, Joseph A. Loo, Kenneth D. Greis, O. Helen Chan, Eric L. Reyner, Elke Lipka, H. D. Hollis Showalter, Patrick W. Vincent, William L. Elliott, William A. Denny
2000217
3
Induced Pluripotent Stem Cell Lines Derived from Equine Fibroblasts
Stem Cell Reviews and Reports ·Kristina Vintersten Nagy, Hoon‐Ki Sung, Puzheng Zhang, Simon Laflamme, Patrick W. Vincent, Siamak Agha‐Mohammadi, Knut Woltjen, Claudio Monetti, Iacovos P. Michael, Lawrence C. Smith, András Nagy
2011180
4
A Sec14p-nodulin domain phosphatidylinositol transfer protein polarizes membrane growth of Arabidopsis thaliana root hairs
The Journal of Cell Biology ·Patrick W. Vincent, Michael Chua, Fabien Nogué, Ashley Fairbrother, Hal Mekeel, Yue Xu, Nina S. Allen, Tatiana N. Bibikova, Simon Gilroy, Vytas A. Bankaitis
2005174
5
Tyrosine Kinase Inhibitors. 15. 4-(Phenylamino)quinazoline and 4-(Phenylamino)pyrido[d]pyrimidine Acrylamides as Irreversible Inhibitors of the ATP Binding Site of the Epidermal Growth Factor Receptor
Journal of Medicinal Chemistry ·Jeff B. Smaill, Brian D. Palmer, Gordon W. Rewcastle, William A. Denny, Dennis J. McNamara, Ellen M. Dobrusin, Alexander J. Bridges, Hairong Zhou, H. D. Hollis Showalter, R. Thomas Winters, Wilbur R. Leopold, David W. Fry, James M. Nelson, Veronika Slintak, William Elliot, Billy Roberts, Patrick W. Vincent, Sandra J. Patmore
1999158
6
Lipid trafficking in plant cells
Progress in Lipid Research ·Patrick Moreau, Jean‐Jacques Bessoule, Sébastien Mongrand, Eric Testet, Patrick W. Vincent, Claude Cassagne
1998130
7
Tyrosine Kinase Inhibitors. 14. Structure−Activity Relationships for Methyl- amino-Substituted Derivatives of 4-[(3-Bromophenyl)amino]-6-(methylamino)- pyrido[3,4-d]pyrimidine (PD 158780), a Potent and Specific Inhibitor of the Tyrosine Kinase Activity of Receptors for the EGF Family of Growth Factors
Journal of Medicinal Chemistry ·Gordon W. Rewcastle, Donna K. Murray, William L. Elliott, David W. Fry, Curtis T. Howard, James M. Nelson, Billy Roberts, Patrick W. Vincent, H. D. Hollis Showalter, R. Thomas Winters, William A. Denny
199898
8
The Diverse Biological Functions of Phosphatidylinositol Transfer Proteins in Eukaryotes
Critical Reviews in Biochemistry and Molecular Biology ·Scott E. Phillips, Patrick W. Vincent, Kellie E. Rizzieri, Gabriel Schaaf, Vytas A. Bankaitis, Eric A. Gaucher
200685
9
Tyrosine Kinase Inhibitors. 18. 6-Substituted 4-Anilinoquinazolines and 4-Anilinopyrido[3,4-d]pyrimidines as Soluble, Irreversible Inhibitors of the Epidermal Growth Factor Receptor
Journal of Medicinal Chemistry ·Jeff B. Smaill, H. D. Hollis Showalter, Hairong Zhou, Alexander J. Bridges, Dennis J. McNamara, David W. Fry, James M. Nelson, Veronika Sherwood, Patrick W. Vincent, Bill J. Roberts, William L. Elliott, William A. Denny
200082
10
Sorafenib is efficacious and tolerated in combination with cytotoxic or cytostatic agents in preclinical models of human non-small cell lung carcinoma
Cancer Chemotherapy and Pharmacology ·Christopher A. Carter, Charles Chen, Cheryl Brink, Patrick W. Vincent, Yulia Maxuitenko, Karen S. Gilbert, William R. Waud, Xiaomei Zhang
200670
11
Isolation of equine bone marrow‐derived mesenchymal stem cells: a comparison between three protocols
Equine Veterinary Journal ·Céline Bourzac, Lawrence C. Smith, Patrick W. Vincent, Guy Beauchamp, J. P. Lavoie, Sheila Laverty
201066
12
Synthesis and structure based optimization of novel Akt inhibitors
Bioorganic & Medicinal Chemistry Letters ·Blaise Lippa, Gonghua Pan, Matthew S. Corbett, Chao Li, Goss S. Kauffman, Jayvardhan Pandit, Shaughnessy Robinson, Liuqing Wei, Ekaterina S. Kozina, Eric S. Marr, Gary Borzillo, Elisabeth Knauth, Elsa Barbacci-Tobin, Patrick W. Vincent, Merin Troutman, Deborah A. Baker, Francis Rajamohan, Shefali Kakar, Tracey Clark, Joel Morris
200864
13
Tyrosine Kinase Inhibitors. 6. Structure−Activity Relationships among N- and 3-Substituted 2,2‘-Diselenobis(1H-indoles) for Inhibition of Protein Tyrosine Kinases and Comparative in Vitro and in Vivo Studies against Selected Sulfur Congeners
Journal of Medicinal Chemistry ·H. D. Hollis Showalter, Anthony D. Sercel, Boguslawa Leja, Craig D. Wolfangel, Linda A. Ambroso, William L. Elliott, David W. Fry, Alan J. Kraker, Curtis T. Howard, Gina H. Lu, Charles Watson Moore, James M. Nelson, Bill J. Roberts, Patrick W. Vincent, William A. Denny, Andrew M. Thompson
199757
14
Preclinical Efficacy of the c-Met Inhibitor CE-355621 in a U87 MG Mouse Xenograft Model Evaluated by18F-FDG Small-Animal PET
Journal of Nuclear Medicine ·Jeffrey R. Tseng, Keon Wook Kang, Mangal Dandekar, Shahriar Yaghoubi, Joseph H. Lee, James G. Christensen, Stephen Muir, Patrick W. Vincent, Neil R. Michaud, Sanjiv S. Gambhir
200751
15
Soluble 2-Substituted Aminopyrido[2,3-d]pyrimidin-7-yl Ureas. Structure−Activity Relationships against Selected Tyrosine Kinases and Exploration of in Vitro and in Vivo Anticancer Activity
Journal of Medicinal Chemistry ·Mel C. Schroeder, James M. Hamby, Cleo J. C. Connolly, Patrick J. Grohar, R. Thomas Winters, Mark R. Barvian, Charles Watson Moore, Stacey L. Boushelle, Sheila Crean, Alan J. Kraker, Denise L. Driscoll, Patrick W. Vincent, William L. Elliott, Gina H. Lu, Brian L. Batley, Tawny K. Dahring, Terry C. Major, Robert L. Panek, Annette M. Doherty, H. D. Hollis Showalter
200149
16
Tyrosine Kinase Inhibitors. 13. Structure−Activity Relationships for Soluble 7-Substituted 4-[(3-Bromophenyl)amino]pyrido[4,3-d]pyrimidines Designed as Inhibitors of the Tyrosine Kinase Activity of the Epidermal Growth Factor Receptor
Journal of Medicinal Chemistry ·Andrew M. Thompson, Donna K. Murray, William L. Elliott, David W. Fry, James A. Nelson, H. D. Hollis Showalter, Bill J. Roberts, Patrick W. Vincent, William A. Denny
199749
17
New α-l-arabinofuranosidase produced by Streptomyces lividans: cloning and DNA sequence of the abfB gene and characterization of the enzyme
Biochemical Journal ·Patrick W. Vincent, François Shareck, Claude Dupont, Rolf Morosoli, D. Kluepfel
199746
18
3-(3,5-Dimethoxyphenyl)-1,6-naphthyridine-2,7-diamines and Related 2-Urea Derivatives Are Potent and Selective Inhibitors of the FGF Receptor-1 Tyrosine Kinase
Journal of Medicinal Chemistry ·Andrew M. Thompson, Cleo J. C. Connolly, James M. Hamby, Stacey L. Boushelle, Brian G. Hartl, Aneesa M. Amar, Alan J. Kraker, Denise L. Driscoll, Randall W. Steinkampf, Sandra J. Patmore, Patrick W. Vincent, Bill J. Roberts, William L. Elliott, Wayne D. Klohs, Wilbur R. Leopold, H. D. Hollis Showalter, William A. Denny
200040
19
Anticancer efficacy of the irreversible EGFr tyrosine kinase inhibitor PD 0169414 against human tumor xenografts
Cancer Chemotherapy and Pharmacology ·Patrick W. Vincent, Alex Bridges, Donald J. Dykes, David W. Fry, W R Leopold, Sandra J. Patmore, Billy Roberts, Steven Rose, Veronika Sherwood, Hairong Zhou, William L. Elliott
200037
20
One of the origins of plasma membrane phosphatidylserine in plant cells is a local synthesis by a serine exchange activity
FEBS Letters ·Patrick W. Vincent, Lilly Maneta‐Peyret, Bénédicte Sturbois-Balcerzak, Michel Duvert, Claude Cassagne, Patrick Moreau
199927

About Patrick W. Vincent

Patrick W. Vincent is a scholar working on Molecular Biology, Oncology, Organic Chemistry, Cell Biology and Pulmonary and Respiratory Medicine, having authored 62 papers that have together received 2.6k indexed citations. Recurring topics across this work include HER2/EGFR in Cancer Research (10 papers), Quinazolinone synthesis and applications (7 papers), Melanoma and MAPK Pathways (7 papers), PI3K/AKT/mTOR signaling in cancer (7 papers), Lung Cancer Treatments and Mutations (7 papers), Synthesis and biological activity (6 papers), Cellular transport and secretion (6 papers) and Reproductive Biology and Fertility (5 papers). The work is most often cited by research in Oncology (886 citations), Molecular Biology (1.4k citations), Pulmonary and Respiratory Medicine (660 citations), Organic Chemistry (569 citations) and Biochemistry (124 citations). Patrick W. Vincent has collaborated with scholars based in United States, Canada and France. Frequent co-authors include James M. Nelson, H. D. Hollis Showalter, William L. Elliott, William A. Denny, Claude Cassagne, David W. Fry, Patrick Moreau, Gordon W. Rewcastle, Jeff B. Smaill and Lawrence C. Smith. Their work appears in journals such as Journal of Medicinal Chemistry, Cancer Research, Molecular Cancer Therapeutics, Bioorganic & Medicinal Chemistry Letters and Biology of Reproduction.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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