Nancy E. Kohl

13.1k citations

100 papers · 8.5k · 3 hit papers · h-index 42

Impact in

Virology top 0.5%
- HIV Research and Treatment
Oncology top 0.5%
- Cancer-related Molecular Pathways

Papers in

Molecular Biology 65
- Protein Kinase Regulation and GTPase Signaling 25
- Ubiquitin and proteasome pathways 8
- PI3K/AKT/mTOR signaling in cancer 8
Oncology 39
- Cancer-related Molecular Pathways 25

Co-authors: Allen Oliff (22 shared papers)Frederick W. Alt (7 shared papers)W. Wayt Gibbs (26 shared papers)Edward M. Scolnick (3 shared papers)Lenora J. Davis (5 shared papers)Richard A. Dixon (3 shared papers)Connie E. Gee (3 shared papers)Samuel Graham (20 shared papers)
Journals: Bioorganic & Medicinal Chemistry Letters (13 papers)Cancer Research (13 papers)Proceedings of the National Academy of Sciences (6 papers)Journal of Medicinal Chemistry (6 papers)Journal of Biological Chemistry (6 papers)
Partner nations: United States Canada Japan

In The Last Decade

Nancy E. Kohl

99 papers receiving 8.3k citations

Nancy E. Kohl's Hit Papers

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Active human immunodeficiency virus protease is required for viral infectivity. 1988 · 1.1k citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

1988 Proceedings of the National Academy of Sciences
1986 Nature
1983 Cell

Peers

Countries citing papers authored by Nancy E. Kohl

Since Specialization

Citations

This map shows the geographic impact of Nancy E. Kohl's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Nancy E. Kohl with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Nancy E. Kohl more than expected).

Fields of papers citing papers by Nancy E. Kohl

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Nancy E. Kohl. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Nancy E. Kohl. The network helps show where Nancy E. Kohl may publish in the future.

Co-authors

The 25 scholars most cited alongside Nancy E. Kohl, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Nancy E. Kohl Line = papers co-authored together Nancy E. Kohl links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 100 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Active human immunodeficiency virus protease is required for viral infectivity. Proceedings of the National Academy of Sciences ·Nancy E. Kohl, Emilio A. Emini, William A. Schleif, Lenora J. Davis, Jill C. Heimbach, Richard A. Dixon, Edward M. Scolnick, Irving S. Sigal Hit paper breakdown →	1988	1098
2	Transposition and amplification of oncogene-related sequences in human neuroblastomas Cell ·Nancy E. Kohl, Naotoshi Kanda, Rhona Schreck, G.A.P. Bruns, Samuel A. Latt, Fred Gilbert, Frederick W. Alt Hit paper breakdown →	1983	609
3	Selective Inhibition of ras -Dependent Transformation by a Farnesyltransferase Inhibitor Science ·Nancy E. Kohl, Scott D. Mosser, S. J. DESOLMS, Elizabeth A. Giuliani, David L. Pompliano, Samuel Graham, Robert L. Smith, Edward M. Scolnick, Allen Oliff, W. Wayt Gibbs	1993	485
4	Differential expression of myc family genes during murine development Nature ·Kathryn A. Zimmerman, George D. Yancopoulos, Robert G. Collum, Russell K. Smith, Nancy E. Kohl, Kathleen Denis, Marion M. Nau, Owen N. Witte, Dominique Toran‐Allerand, Connie E. Gee, John D. Minna, Frederick W. Alt Hit paper breakdown →	1986	483
5	Farnesyltransferase inhibitors: Ras research yields a potential cancer therapeutic Cell ·Jackson B. Gibbs, Allen Oliff, Nancy E. Kohl	1994	441
6	Glioblastoma Eradication Following Immune Checkpoint Blockade in an Orthotopic, Immunocompetent Model Cancer Immunology Research ·David A. Reardon, Prafulla C. Gokhale, Sarah R. Klein, Keith L. Ligon, Scott J. Rodig, Shakti Ramkissoon, Kristen L. Jones, Amy Saur Conway, Xiaoyun Liao, Jun Zhou, Patrick Y. Wen, Annick D. Van den Abbeele, F. Stephen Hodi, Lei Qin, Nancy E. Kohl, Arlene H. Sharpe, Glenn Dranoff, Gordon J. Freeman	2015	306
7	Lung Cancer Cell Lines Harboring MET Gene Amplification Are Dependent on Met for Growth and Survival Cancer Research ·Bart Lutterbach, Qinwen Zeng, Lenora J. Davis, Harold Hatch, Gaozhen Hang, Nancy E. Kohl, W. Wayt Gibbs, Bo‐Sheng Pan	2007	261
8	Human N-myc is closely related in organization and nucleotide sequence to c-myc Nature ·Nancy E. Kohl, Edith Legouy, Ronald A. DePinho, Perry D. Nisen, Russell K. Smith, Connie E. Gee, Frederick W. Alt	1986	252
9	First Selective Small Molecule Inhibitor of FGFR4 for the Treatment of Hepatocellular Carcinomas with an Activated FGFR4 Signaling Pathway Cancer Discovery ·Margit Hagel, Chandra Miduturu, Michael P. Sheets, Nooreen Rubin, Weifan Weng, Nicolas Stransky, Neil Bifulco, Joseph L. Kim, Brian L. Hodous, Natasja Brooijmans, Adam Shutes, Christopher Winter, Christoph Lengauer, Nancy E. Kohl, Timothy J. Guzi	2015	251
10	Protein farnesyltransferase inhibitors block the growth of ras-dependent tumors in nude mice. Proceedings of the National Academy of Sciences ·Nancy E. Kohl, Francine R. Wilson, S D Mosser, Elizabeth A. Giuliani, S. J. DESOLMS, Michael W. Conner, Neville J. Anthony, W J Holtz, R P Gomez, T J Lee	1994	247
11	Induction of apoptosis by an inhibitor of the mitotic kinesin KSP requires both activation of the spindle assembly checkpoint and mitotic slippage Cancer Cell ·Weikang Tao, Victoria J. South, Yun Zhang, Joseph P. Davide, Linda Farrell, Nancy E. Kohl, Laura Sepp‐Lorenzino, Robert B. Lobell	2005	229
12	Selective inhibition of farnesyl-protein transferase blocks ras processing in vivo. Journal of Biological Chemistry ·W. Wayt Gibbs, D. L. Pompliano, S.D. Mosser, Elaine Rands, R. B. Lingham, Shashi Bala Singh, Edward M. Scolnick, Nancy E. Kohl, Allen Oliff	1993	223
13	Activated Expression of the N- myc Gene in Human Neuroblastomas and Related Tumors Science ·Nancy E. Kohl, Connie E. Gee, Frederick W. Alt	1984	209
14	Farnesyltransferase Inhibition Causes Morphological Reversion of ras -Transformed Cells by a Complex Mechanism That Involves Regulation of the Actin Cytoskeleton Molecular and Cellular Biology ·George C. Prendergast, Joseph P. Da Vide, S. J. DESOLMS, Elizabeth A. Giuliani, Samuel Graham, W. Wayt Gibbs, Allen Oliff, Nancy E. Kohl	1994	177
15	Farnesyl transferase inhibitors cause enhanced mitotic sensitivity to taxol and epothilones Proceedings of the National Academy of Sciences ·Mark M. Moasser, Laura Sepp‐Lorenzino, Nancy E. Kohl, Allen Oliff, Aaron Balog, Dai‐Shi Su, Samuel J. Danishefsky, Neal Rosen	1998	163
16	N-myc can cooperate with ras to transform normal cells in culture. Proceedings of the National Academy of Sciences ·G D Yancopoulos, Perry D. Nisen, Abeba Tesfaye, Nancy E. Kohl, Mitchell Goldfarb, F W Alt	1985	162
17	A Farnesyltransferase Inhibitor Induces Tumor Regression in Transgenic Mice Harboring Multiple Oncogenic Mutations by Mediating Alterations in Both Cell Cycle Control and Apoptosis Molecular and Cellular Biology ·Rebecca E. Barrington, Mark A. Subler, Elaine Rands, Charles A. Omer, Patricia Miller, Jeffrey E. Hundley, Steven K. Koester, Dean A. Troyer, David J. Bearss, Michael W. Conner, W. Wayt Gibbs, Kelly Hamilton, Kenneth S. Koblan, Scott D. Mosser, Timothy J. O’Neill, Michael D. Schaber, Edith T. Senderak, Jolene J. Windle, Allen Oliff, Nancy E. Kohl	1998	146
18	Structure and expression of the murine N-myc gene. Proceedings of the National Academy of Sciences ·Ronald A. DePinho, Edith Legouy, Lori B. Feldman, Nancy E. Kohl, George D. Yancopoulos, Frederick W. Alt	1986	140
19	Farnesyltransferase inhibition causes morphological reversion of ras-transformed cells by a complex mechanism that involves regulation of the actin cytoskeleton. Molecular and Cellular Biology ·George C. Prendergast, Joseph P. Davide, S. J. DESOLMS, Elizabeth A. Giuliani, Samuel Graham, W. Wayt Gibbs, A Oliff, Nancy E. Kohl	1994	131
20	Kinesin spindle protein (KSP) inhibitors. Part 1: The discovery of 3,5-diaryl-4,5-dihydropyrazoles as potent and selective inhibitors of the mitotic kinesin KSP Bioorganic & Medicinal Chemistry Letters ·Christopher D. Cox, Michael J. Breslin, Brenda J. Mariano, Paul J. Coleman, Carolyn A. Buser, Eileen S. Walsh, Kelly Hamilton, Hans E. Huber, Nancy E. Kohl, Maricel Torrent, Youwei Yan, Laurence C. Kuo, George D. Hartman	2005	118

About Nancy E. Kohl

Nancy E. Kohl is a scholar working on Molecular Biology, Oncology, Cancer Research, Organic Chemistry and Cell Biology, having authored 100 papers that have together received 8.5k indexed citations. Recurring topics across this work include Protein Kinase Regulation and GTPase Signaling (25 papers), Cancer-related Molecular Pathways (25 papers), Cancer, Hypoxia, and Metabolism (10 papers), Neuroblastoma Research and Treatments (9 papers), Click Chemistry and Applications (9 papers), Ubiquitin and proteasome pathways (8 papers), PI3K/AKT/mTOR signaling in cancer (8 papers) and Microtubule and mitosis dynamics (7 papers). The work is most often cited by research in Virology (867 citations), Oncology (2.4k citations), Neurology (1.1k citations), Molecular Biology (5.4k citations) and Cancer Research (819 citations). Nancy E. Kohl has collaborated with scholars based in United States, Canada and Japan. Frequent co-authors include Allen Oliff, Frederick W. Alt, W. Wayt Gibbs, Edward M. Scolnick, Lenora J. Davis, Richard A. Dixon, Connie E. Gee, Samuel Graham, S. J. DESOLMS and Jill C. Heimbach. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Cancer Research, Proceedings of the National Academy of Sciences, Journal of Medicinal Chemistry and Journal of Biological Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Nancy E. Kohl

Nancy E. Kohl's Hit Papers

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About Nancy E. Kohl

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