Mike Hutton

15.5k citations

85 papers · 9.1k · 4 hit papers · h-index 41

Impact in

Physiology top 0.1%
- Alzheimer's disease research and treatments
Neurology top 0.2%
- Parkinson's Disease Mechanisms and Treatments
- Amyotrophic Lateral Sclerosis Research
- Neuroinflammation and Neurodegeneration Mechanisms

Papers in

Physiology 40
- Alzheimer's disease research and treatments 38
Neurology 25
- Parkinson's Disease Mechanisms and Treatments 18
- Amyotrophic Lateral Sclerosis Research 10
- Neurological diseases and metabolism 8

Co-authors: Jada Lewis (12 shared papers)John Hardy (20 shared papers)Dennis W. Dickson (13 shared papers)Eileen McGowan (8 shared papers)Debra Yager (2 shared papers)Chris Eckman (2 shared papers)Karen Duff (6 shared papers)Jordi Pérez‐Tur (7 shared papers)
Journals: Journal of Neuroscience (4 papers)Annals of Neurology (4 papers)Journal of Biological Chemistry (4 papers)Journal of Neuropathology & Experimental Neurology (3 papers)European Spine Journal (3 papers)
Partner nations: United States United Kingdom Switzerland

In The Last Decade

Mike Hutton

84 papers receiving 8.9k citations

Mike Hutton's Hit Papers

align trajectories log scale

Enhanced Neurofibrillary Degeneration in Transgenic Mice Expressing Mutant Tau and APP 2001 · 1.2k citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2001 Science
2001 Science
1998 FEBS Letters
1996 Nature

Peers

Countries citing papers authored by Mike Hutton

Since Specialization

Citations

This map shows the geographic impact of Mike Hutton's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Mike Hutton with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Mike Hutton more than expected).

Fields of papers citing papers by Mike Hutton

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Mike Hutton. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Mike Hutton. The network helps show where Mike Hutton may publish in the future.

Co-authors

The 25 scholars most cited alongside Mike Hutton, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Mike Hutton Line = papers co-authored together Mike Hutton links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 85 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Enhanced Neurofibrillary Degeneration in Transgenic Mice Expressing Mutant Tau and APP Science ·Jada Lewis, Dennis W. Dickson, Wen-Lang Lin, Louise Chisholm, Anthony Corral, Graham L. Jones, Shu‐Hui Yen, Naruhiko Sahara, Lisa Skipper, Debra Yager, Chris Eckman, John Hardy, Mike Hutton, Eileen McGowan Hit paper breakdown →	2001	1204
2	Increased amyloid-β42(43) in brains of mice expressing mutant presenilin 1 Nature ·Karen Duff, Chris Eckman, Cindy Zehr, Xin Yu, Cristian-Mihail Prada, Jordi Pérez‐Tur, Mike Hutton, Luc Buée, Yasuo Harigaya, Debra Yager, David Morgan, Marcia N. Gordon, Leigh A. Holcomb, Lawrence M. Refolo, B. Zenk, John Hardy, Steven G. Younkin Hit paper breakdown →	1996	1175
3	Tauopathy in Drosophila : Neurodegeneration Without Neurofibrillary Tangles Science ·Curtis W. Wittmann, Matthew Wszolek, Joshua M. Shulman, Paul M. Salvaterra, Jada Lewis, Mike Hutton, Mel Β. Feany Hit paper breakdown →	2001	730
4	TNF‐α converting enzyme (TACE) is inhibited by TIMP‐3 FEBS Letters ·Augustin Amour, Patrick M. Slocombe, Ailsa Webster, Michael J. Butler, Christopher G. Knight, Bryan John Smith, Paul E. Stephens, Chris Shelley, Mike Hutton, Vera Knäuper, Andrew Docherty, Gillian Murphy Hit paper breakdown →	1998	518
5	Aβ42 Is Essential for Parenchymal and Vascular Amyloid Deposition in Mice Neuron ·Eileen McGowan, Fiona Pickford, Jungsu Kim, Luisa Onstead, Jason L. Eriksen, Cindy Yu, Lisa Skipper, Michael P. Murphy, J. David Beard, Pritam Das, Karen Jansen, Michael W. DeLucia, Wen-Lang Lin, Georgia Dolios, Rong Wang, Christopher B. Eckman, Dennis W. Dickson, Mike Hutton, John Hardy, Todd E. Golde	2005	471
6	Wild-Type Human TDP-43 Expression Causes TDP-43 Phosphorylation, Mitochondrial Aggregation, Motor Deficits, and Early Mortality in Transgenic Mice Journal of Neuroscience ·Ya-Fei Xu, Tania F. Gendron, Yong‐Jie Zhang, Wen-Lang Lin, Simon D’Alton, (unknown), Monica Castanedes Casey, Jimei Tong, Joshua A. Knight, Xin Yu, Rosa Rademakers, Khrista Boylan, Mike Hutton, Eileen McGowan, Dennis W. Dickson, Jada Lewis, Leonard Petrucelli	2010	425
7	Accumulation of Pathological Tau Species and Memory Loss in a Conditional Model of Tauopathy Journal of Neuroscience ·Zdenek Berger, Hanno M. Roder, Amanda Hanna, Aaron Carlson, Vijayaraghavan Rangachari, Mei Yue, Zbigniew K. Wszołek, Karen H. Ashe, Joshua A. Knight, Dennis W. Dickson, Cathy Andorfer, Terrone L. Rosenberry, Jada Lewis, Mike Hutton, Christopher Janus	2007	391
8	Genetic dissection of Alzheimer's disease and related dementias: amyloid and its relationship to tau Nature Neuroscience ·John Hardy, Karen Duff, Katrina Gwinn Hardy, Jordi Pérez‐Tur, Mike Hutton	1998	269
9	A variant of Alzheimer's disease with spastic paraparesis and unusual plaques due to deletion of exon 9 of presenilin 1 Nature Medicine ·Richard Crook, Auli Verkkoniemi, Jordi Pérez‐Tur, Nitin D. Mehta, Matt Baker, Henry Houlden, Matthew J. Farrer, Mike Hutton, Sarah Lincoln, John Hardy, Katrina Gwinn, Mirja Somer, Anders Paetau, Hannu Kalimo, Raija Ylikoski, Minna Pöyhönen, Steve Kucera, Matti Haltia	1998	266
10	Matrix metalloproteinases in arthritic disease. Arthritis Research ·Gillian Murphy, Vera Knäuper, Susan J. Atkinson, George Butler, William English, Mike Hutton, Jan Olaf Stracke, Ian M. Clark	2002	257
11	5′ Splice Site Mutations in tau Associated with the Inherited Dementia FTDP-17 Affect a Stem-Loop Structure That Regulates Alternative Splicing of Exon 10 Journal of Biological Chemistry ·Andrew Grover, Henry Houlden, Matt Baker, Jennifer Adamson, Jada Lewis, Guy Prihar, Stuart Pickering‐Brown, Karen Duff, Mike Hutton	1999	240
12	Accelerated filament formation from tau protein with specific FTDP‐17 missense mutations FEBS Letters ·Parimala Nacharaju, Jada Lewis, Colin Easson, Samuel Yen, Samuel Yen, Jennifer Hackett, Mike Hutton, Shu-Hui Yen	1999	238
13	Induction of Tau Pathology by Intracerebral Infusion of Amyloid-β-Containing Brain Extract and by Amyloid-β Deposition in APP × Tau Transgenic Mice American Journal Of Pathology ·Tristan Bolmont, Florence Clavaguera, Melanie Meyer‐Luehmann, Martin C. Herzig, Rebecca Radde, Matthias Staufenbiel, Jada Lewis, Mike Hutton, Markus Tolnay, Mathias Jucker	2007	225
14	Argyrophilic Grain Disease Is a Sporadic 4-Repeat Tauopathy Journal of Neuropathology & Experimental Neurology ·Takashi Togo, Naruhiko Sahara, Shu-Hui Yen, Natalie Cookson, Takashi Ishizawa, Mike Hutton, Rohan de Silva, Andrew J. Lees, Dennis W. Dickson	2002	214
15	Biochemical Characterization of the Catalytic Domain of Human Matrix Metalloproteinase 19 Journal of Biological Chemistry ·Jan Olaf Stracke, Mike Hutton, Margaret L. Stewart, Alberto M. Pendás, Bryan Ronain Smith, Carlos López-Otı́n, Gillian Murphy, Vera Knäuper	2000	118
16	Linkage Disequilibrium and Association of MAPT H1 in Parkinson Disease The American Journal of Human Genetics ·Lisa Skipper, Kristen Wilkes, Mathias Toft, Matthew Baker, Sarah Lincoln, Mary Hulihan, Owen A. Ross, Mike Hutton, Jan Aasly, Matthew J. Farrer	2004	115
17	Assembly of tau in transgenic animals expressing P301L tau: alteration of phosphorylation and solubility Journal of Neurochemistry ·Naruhiko Sahara, Jada Lewis, Michael DeTure, Eileen McGowan, Dennis W. Dickson, Mike Hutton, Shu‐Hui Yen	2002	100
18	Refining frontotemporal dementia with parkinsonism linked to chromosome 17: introducing FTDP-17 (MAPT) and FTDP-17 (PGRN). PubMed ·Bradley F. Boeve, Mike Hutton	2008	100
19	Pick's disease is associated with mutations in thetau gene Annals of Neurology ·Stuart Pickering‐Brown, Matt Baker, Shu‐Hui Yen, Wan-Kyng Liu, Masato Hasegawa, Nigel J. Cairns, P. L. Lantos, Martin N. Rossor, Takeshi Iwatsubo, Yvonne Davies, David Allsop, Rob Furlong, F. Owen, John Hardy, David Mann, Mike Hutton	2000	99
20	Multi-metric behavioral comparison of APPsw and P301L models for Alzheimer's Disease: linkage of poorer cognitive performance to tau pathology in forebrain Brain Research ·Gary W. Arendash, Jada Lewis, Ralph E. Leighty, Eileen McGowan, Jennifer R. Cracchiolo, Mike Hutton, Marcos F Garcia	2004	97

About Mike Hutton

Mike Hutton is a scholar working on Physiology, Neurology, Molecular Biology, Cellular and Molecular Neuroscience and Cancer Research, having authored 85 papers that have together received 9.1k indexed citations. Recurring topics across this work include Alzheimer's disease research and treatments (38 papers), Parkinson's Disease Mechanisms and Treatments (18 papers), Protease and Inhibitor Mechanisms (12 papers), Amyotrophic Lateral Sclerosis Research (10 papers), Nuclear Receptors and Signaling (10 papers), Neurological diseases and metabolism (8 papers), Peptidase Inhibition and Analysis (7 papers) and Cholinesterase and Neurodegenerative Diseases (7 papers). The work is most often cited by research in Physiology (5.5k citations), Neurology (1.5k citations), Neurology (1.9k citations), Cellular and Molecular Neuroscience (1.9k citations) and Pharmacology (1.4k citations). Mike Hutton has collaborated with scholars based in United States, United Kingdom and Switzerland. Frequent co-authors include Jada Lewis, John Hardy, Dennis W. Dickson, Eileen McGowan, Debra Yager, Chris Eckman, Karen Duff, Jordi Pérez‐Tur, Gillian Murphy and Shu‐Hui Yen. Their work appears in journals such as Journal of Neuroscience, Annals of Neurology, Journal of Biological Chemistry, Journal of Neuropathology & Experimental Neurology and European Spine Journal.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Mike Hutton

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Mike Hutton

Mike Hutton's Hit Papers

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Fields of papers citing papers by Mike Hutton

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About Mike Hutton

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