Michael E. Pierce

1.5k citations

26 papers · 1.3k · 1 hit paper · h-index 15

Impact in

Organic Chemistry top 2%
- Synthesis of Tetrazole Derivatives
- Multicomponent Synthesis of Heterocycles
- Synthesis and Characterization of Heterocyclic Compounds
- Asymmetric Synthesis and Catalysis
Pharmaceutical Science top 5%
- Fluorine in Organic Chemistry

Papers in

Organic Chemistry 21
- Asymmetric Synthesis and Catalysis 7
- Carbohydrate Chemistry and Synthesis 4
- Synthetic Organic Chemistry Methods 3
- Chemical Reaction Mechanisms 3
- Chemical Synthesis and Reactions 2
Infectious Diseases 6
- HIV/AIDS drug development and treatment 6

Co-authors: John V. Duncia (3 shared papers)Joseph B. Santella (2 shared papers)David J. Carini (3 shared papers)Gregory J. Wells (2 shared papers)Andrew T. Chiu (1 shared paper)A.L. Johnson (1 shared paper)Paul E. Aldrich (1 shared paper)William A. Price (1 shared paper)
Journals: Tetrahedron Letters (6 papers)The Journal of Organic Chemistry (5 papers)Organic Process Research & Development (3 papers)Antimicrobial Agents and Chemotherapy (1 paper)Tetrahedron Asymmetry (1 paper)
Partner nations: United States Japan

In The Last Decade

Michael E. Pierce

26 papers receiving 1.2k citations

Michael E. Pierce's Hit Papers

align trajectories log scale

Nonpeptide angiotensin II receptor antagonists: the discovery of a series of N-(biphenylylmethyl)imidazoles as potent, orally active antihypertensives 1991 · 390 citations

What are hit papers?

Paper score: A paper's citations measured against the top-1% bar of its own field and year: the square root of citations ÷ bar, so 1 means right at the bar and 2 means four times its citations. The bar blends the citation counts that enter the top 1% of the paper's subfields in its year (weighted 89.5%), of those subfields over all years (0.5%) and of its year across all fields (10%); a subfield and year with fewer than 400 papers takes its year's bar. Papers from 2026 are not scored yet: in an unfinished year, when a paper appeared matters more than how it is cited.

Hit paper: A paper cited at least 1.5× the top-1% bar of its field and year: a paper score of at least √1.5.

1991 Journal of Medicinal Chemistry

Peers

Countries citing papers authored by Michael E. Pierce

Since Specialization

Citations

This map shows the geographic impact of Michael E. Pierce's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael E. Pierce with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael E. Pierce more than expected).

Fields of papers citing papers by Michael E. Pierce

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael E. Pierce. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael E. Pierce. The network helps show where Michael E. Pierce may publish in the future.

Co-authors

The 25 scholars most cited alongside Michael E. Pierce, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Michael E. Pierce Line = papers co-authored together Michael E. Pierce links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Showing the 20 most-cited of 26 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Nonpeptide angiotensin II receptor antagonists: the discovery of a series of N-(biphenylylmethyl)imidazoles as potent, orally active antihypertensives Journal of Medicinal Chemistry ·David J. Carini, John V. Duncia, Paul E. Aldrich, Andrew T. Chiu, A.L. Johnson, Michael E. Pierce, William A. Price, Joseph B. Santella Hit paper breakdown →	1991	390
2	Three synthetic routes to a sterically hindered tetrazole. A new one-step mild conversion of an amide into a tetrazole The Journal of Organic Chemistry ·John V. Duncia, Michael E. Pierce, Joseph B. Santella	1991	283
3	Practical Asymmetric Synthesis of Efavirenz (DMP 266), an HIV-1 Reverse Transcriptase Inhibitor The Journal of Organic Chemistry ·Michael E. Pierce, Rodney L. Parsons, Lilian A. Radesca, Young S. Lo, Stuart G. Silverman, Mia Moore, Qamrul Islam, Anusuya Choudhury	1998	192
4	A Practical Preparation of Terminal Alkynes from Aldehydes The Journal of Organic Chemistry ·Zhe Wang, Silvio Campagna, Kaihong Yang, Guoyou Xu, Michael E. Pierce, Joseph Fortunak, Pat N. Confalone	2000	57
5	Stereoselective Synthesis of HIV-1 Protease Inhibitor, DMP 323 The Journal of Organic Chemistry ·Michael E. Pierce, Gregory D. Harris, Qamrul Islam, Lilian A. Radesca, Louis Storace, Robert E. Waltermire, Ed Wat, Prabhakar K. Jadhav	1996	51
6	Practical synthesis and regioselective alkylation of methyl 4(5)-(pentafluoroethyl)-2-propylimidazole-5(4)-carboxylate to give DuP 532, a potent angiotensin II antagonist The Journal of Organic Chemistry ·Michael E. Pierce, David J. Carini, George F. Huhn, Gregory J. Wells, JOHN F. ARNETT	1993	42
7	DPC 817: a Cytidine Nucleoside Analog with Activity against Zidovudine- and Lamivudine-Resistant Viral Variants Antimicrobial Agents and Chemotherapy ·Raymond F. Schinazi, John W. Mellors, Holly Bazmi, Sharon Diamond, Sena Garber, Karen Gallagher, Romas Geleziunas, Ron Klabe	2002	41
8	Kinetics and Mechanism of Hydrolysis of Efavirenz Pharmaceutical Research ·Michael B. Maurin, Susan M. Rowe, Karl F. Blom, Michael E. Pierce	2002	37
9	Enantioselective synthesis of β-hydroxy carboxylic acids: direct conversion of β-oxocarboxylic acids to enantiomerically enriched β-hydroxy carboxylic acids via neighboring group control Tetrahedron Asymmetry ·Zhe Wang, Zhao Chunlin, Michael E. Pierce, Joseph Fortunak	1999	29
10	A concise synthesis of anti-viral agent F-ddA, starting from (S)-dihydro-5-(hydroxymethyl)-2(3H)-furanone Tetrahedron Letters ·Anusuya Choudhury, Fuqiang Jin, Dengjin Wang, Zhe Wang, Guoyou Xu, Dieu Nguyen, John A. Castoro, Michael E. Pierce	2003	27
11	Synthesis of HIV-1 Reverse Transcriptase Inhibitor DMP 266 Synthetic Communications ·Lilian A. Radesca, Young S. Lo, Mia Moore, Michael E. Pierce	1997	26
12	A new and practical synthesis of vinyl dichlorides via a non-Wittig-type approach Tetrahedron Letters ·Zhe Wang, Silvio Campagna, Guoyou Xu, Michael E. Pierce, Joseph Fortunak, Pat N. Confalone	2000	22
13	Mono-nitration of aromatic compounds via their nitric acid salts Tetrahedron Letters ·Pingsheng Zhang, Miall Cedilote, Thomas P. Cleary, Michael E. Pierce	2007	20
14	In Situ Recycling of Chiral Ligand and Surplus Nucleophile for a Noncatalytic Reaction: Amplification of Process Throughput in the Asymmetric Addition Step of Efavirenz (DMP 266) Organic Process Research & Development ·Anusuya Choudhury, Mia Moore, Michael E. Pierce, Joseph Fortunak, Ioannis I. Valvis, Pat N. Confalone	2003	18
15	A Large Scale Preparation of the Cognitive Enhancer Linopirdine Synthetic Communications ·Walter M. Bryant, George F. Huhn, James H. Jensen, Michael E. Pierce, Christian Stammbach	1993	17
16	The Discovery and Development of Angiotensin II Antagonists Kluwer Academic Publishers eBooks ·David J. Carini, David D. Christ, John V. Duncia, Michael E. Pierce	2006	14
17	A Practical Method For Stabilizing Lithiated Halogenated Aromatic Compounds Organic Process Research & Development ·Thimma Rawalpally, Yaohui Ji, Ashish Shankar, William Edwards, Joshua Lee Allen, Yong Jiang, Thomas P. Cleary, Michael E. Pierce	2008	12
18	Chemoselective allylic addition of allyltrichlorosilane to α-oxocarboxylic acids: synthesis of tertiary α-hydroxy carboxylic acids Tetrahedron Letters ·Zhe Wang, Guoyou Xu, Dengjin Wang, Michael E. Pierce, Pat N. Confalone	2000	10
19	Synthesis of D-D4FC, a biologically active nucleoside via an unprecedented palladium mediated Ferrier rearrangement-type glycosidation with an aromatization prone xylo-furanoid glycal Tetrahedron Letters ·Anusuya Choudhury, Michael E. Pierce, Dieu Nguyen, Louis Storace, Pat N. Confalone	2005	7
20	Crystal form control and particle size control of RG3487, a nicotinic α7 receptor partial agonist International Journal of Pharmaceutics ·Shan-Ming Kuang, Pingsheng Zhang, Eric Z. Dong, Geremia Jennings, Baoshu Zhao, Michael E. Pierce	2016	6

About Michael E. Pierce

Michael E. Pierce is a scholar working on Organic Chemistry, Infectious Diseases, Pharmaceutical Science, Inorganic Chemistry and Molecular Biology, having authored 26 papers that have together received 1.3k indexed citations. Recurring topics across this work include Asymmetric Synthesis and Catalysis (7 papers), HIV/AIDS drug development and treatment (6 papers), Chemical Synthesis and Analysis (4 papers), Carbohydrate Chemistry and Synthesis (4 papers), Synthetic Organic Chemistry Methods (3 papers), Chemical Reaction Mechanisms (3 papers), Biochemical and Molecular Research (2 papers) and Chemical Synthesis and Reactions (2 papers). The work is most often cited by research in Organic Chemistry (942 citations), Pharmaceutical Science (137 citations), Virology (65 citations), Inorganic Chemistry (99 citations) and Infectious Diseases (119 citations). Michael E. Pierce has collaborated with scholars based in United States and Japan. Frequent co-authors include John V. Duncia, Joseph B. Santella, David J. Carini, Gregory J. Wells, Andrew T. Chiu, A.L. Johnson, Paul E. Aldrich, William A. Price, Pat N. Confalone and Joseph Fortunak. Their work appears in journals such as Tetrahedron Letters, The Journal of Organic Chemistry, Organic Process Research & Development, Antimicrobial Agents and Chemotherapy and Tetrahedron Asymmetry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

Michael E. Pierce

Impact in

Papers in i

In The Last Decade

Michael E. Pierce

Michael E. Pierce's Hit Papers

Peers

Countries citing papers authored by Michael E. Pierce

Fields of papers citing papers by Michael E. Pierce

All Works

About Michael E. Pierce

Explore authors with similar magnitude of impact

Papers in