Michael Downes

39.1k citations
187 papers · 31.5k · 20 hit papers · h-index 78

Impact in

Papers in

    • Peroxisome Proliferator-Activated Receptors 22
    • Genomics and Chromatin Dynamics 19
    • Muscle Physiology and Disorders 15
    • Fibroblast Growth Factor Research 14
    • Drug Transport and Resistance Mechanisms 16
    • Pancreatic and Hepatic Oncology Research 14

Michael Downes

181 papers receiving 30.8k citations

Michael Downes's Hit Papers

Obesity causes mitochondrial fragmentation and dysfunction in white adipocytes due to RalA activation 2024 · 105 citations
1050+6+12Years since publication5001k1.5k

Peers

Michael Downes
Comparison fields: 5 of 168
  • Endocrine and Autonomic Systems 2.4k
  • Molecular Biology 13.3k
  • Oncology 3.6k
  • Aging 220
  • Hepatology 969
Replace Ruth T. Yu with:
Ruth T. Yu United States
Nicoletta Sacchi Italy
Alan R. Saltiel United States
Mitchell A. Lazar United States
Morris J. Birnbaum United States
Walter Wahli Switzerland
David D. Moore United States
Wei Jun Gu United States
Peter Tontonoz United States
David J. Mangelsdorf United States
Michael Downes relative to Ruth T. Yu United States Ruth T. Yu's profile →
Citations per field
00.5×1.5×1.8×
Ruth T. Yu · 1×
Citations per year

Countries citing papers authored by Michael Downes

Since Specialization
Citations

This map shows the geographic impact of Michael Downes's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael Downes with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael Downes more than expected).

Fields of papers citing papers by Michael Downes

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael Downes. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael Downes. The network helps show where Michael Downes may publish in the future.

Co-authors

The 25 scholars most cited alongside Michael Downes, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Michael Downes Line = papers co-authored together Michael Downes links everyone, so they are left out of the graph.

All Works

20 of 20 papers shown

Showing the 20 most-cited of 187 papers — load more, or switch the sort, to bring in the rest.

#Work
1
The Genome Sequence of Drosophila melanogaster
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20004725
2
PPARγ signaling and metabolism: the good, the bad and the future
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20131696
3
Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells
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20111258
4
AMPK and PPARδ Agonists Are Exercise Mimetics
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20081041
5
Regulation of antibacterial defense in the small intestine by the nuclear bile acid receptor
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2006993
6
Vitamin D Receptor-Mediated Stromal Reprogramming Suppresses Pancreatitis and Enhances Pancreatic Cancer Therapy
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2014975
7
Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β
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2012900
8
Anatomical Profiling of Nuclear Receptor Expression Reveals a Hierarchical Transcriptional Network
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2006856
9
Nuclear Receptor Expression Links the Circadian Clock to Metabolism
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2006815
10
Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance
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2015642
11
Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction in CD8+ T cells in tumors
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2021639
12
Humanized xenobiotic response in mice expressing nuclear receptor SXR
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2000569
13
A Vitamin D Receptor/SMAD Genomic Circuit Gates Hepatic Fibrotic Response
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2013537
14 2011504
15 2011480
16
Global chemical effects of the microbiome include new bile-acid conjugations
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2020477
17 2017476
18
An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice
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2013386
19 2019385
20 2007365

About Michael Downes

Michael Downes is a scholar working on Molecular Biology, Oncology, Physiology, Endocrine and Autonomic Systems and Cellular and Molecular Neuroscience, having authored 187 papers that have together received 31.5k indexed citations. Recurring topics across this work include Adipose Tissue and Metabolism (25 papers), Peroxisome Proliferator-Activated Receptors (22 papers), Genomics and Chromatin Dynamics (19 papers), Estrogen and related hormone effects (19 papers), Drug Transport and Resistance Mechanisms (16 papers), Muscle Physiology and Disorders (15 papers), Pancreatic and Hepatic Oncology Research (14 papers) and Fibroblast Growth Factor Research (14 papers). The work is most often cited by research in Endocrine and Autonomic Systems (2.4k citations), Molecular Biology (13.3k citations), Oncology (3.6k citations), Aging (220 citations) and Hepatology (969 citations). Michael Downes has collaborated with scholars based in United States, Australia and Switzerland. Frequent co-authors include Ronald Evans, Ruth T. Yu, Christopher Liddle, Annette R. Atkins, David J. Mangelsdorf, Nasun Hah, Angie L. Bookout, Maryam Ahmadian, Jae Myoung Suh and Grant D. Barish. Their work appears in journals such as Proceedings of the National Academy of Sciences, Cell Metabolism, Nature, Cell and Molecular Endocrinology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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