Michael Downes

38.3k citations
169 papers · 21.0k · 12 hit papers · h-index 68

Impact in

Papers in

    • Retinoids in leukemia and cellular processes 21
    • Epigenetics and DNA Methylation 15
    • Fibroblast Growth Factor Research 13
    • Peroxisome Proliferator-Activated Receptors 12
    • Adipose Tissue and Metabolism 34

Michael Downes

168 papers receiving 20.7k citations

Michael Downes's Hit Papers

A Universal Gut-Microbiome-Derived Signature Predicts Cirrhosis 2020 · 240 citations
2400+8+17Years since publication50010001.5k

Peers

Michael Downes
Comparison fields: 5 of 156
  • Aging 620
  • Endocrine and Autonomic Systems 2.2k
  • Physiology 5.2k
  • Molecular Biology 11.4k
  • Endocrinology, Diabetes and Metabolism 2.0k
Replace Ruth T. Yu with:
Ruth T. Yu United States
Morris J. Birnbaum United States
Thomas P. Burris United States
Jason K. Kim United States
Benoı̂t Viollet France
Oksana Gavrilova United States
Kohjiro Ueki Japan
Domenico Accili United States
Reuben J. Shaw United States
Mark A. Magnuson United States
Michael Downes relative to Ruth T. Yu United States Ruth T. Yu's profile →
Citations per field
00.5×1.6×
Ruth T. Yu · 1×
Citations per year

Countries citing papers authored by Michael Downes

Since Specialization
Citations

This map shows the geographic impact of Michael Downes's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael Downes with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael Downes more than expected).

Fields of papers citing papers by Michael Downes

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael Downes. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael Downes. The network helps show where Michael Downes may publish in the future.

Co-authors

The 25 scholars most cited alongside Michael Downes, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Michael Downes Line = papers co-authored together Michael Downes links everyone, so they are left out of the graph.

All Works

20 of 20 papers shown

Showing the 20 most-cited of 169 papers — load more, or switch the sort, to bring in the rest.

#Work
1
PPARγ signaling and metabolism: the good, the bad and the future
Hit paper breakdown →
20131541
2
Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells
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20111124
3
AMPK and PPARδ Agonists Are Exercise Mimetics
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2008968
4
Regulation of antibacterial defense in the small intestine by the nuclear bile acid receptor
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2006924
5
Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β
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2012831
6
Anatomical Profiling of Nuclear Receptor Expression Reveals a Hierarchical Transcriptional Network
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2006811
7
Nuclear Receptor Expression Links the Circadian Clock to Metabolism
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2006770
8
Humanized xenobiotic response in mice expressing nuclear receptor SXR
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2000545
9
A Vitamin D Receptor/SMAD Genomic Circuit Gates Hepatic Fibrotic Response
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2013490
10 1998477
11 2011463
12 2011445
13 2013353
14 2007350
15 2000350
16
FXR Regulates Intestinal Cancer Stem Cell Proliferation
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2019331
17 2003310
18 2001266
19 2015261
20 2007254

About Michael Downes

Michael Downes is a scholar working on Molecular Biology, Physiology, Genetics, Oncology and Epidemiology, having authored 169 papers that have together received 21.0k indexed citations. Recurring topics across this work include Adipose Tissue and Metabolism (34 papers), Estrogen and related hormone effects (26 papers), Retinoids in leukemia and cellular processes (21 papers), Epigenetics and DNA Methylation (15 papers), Liver Disease Diagnosis and Treatment (15 papers), Drug Transport and Resistance Mechanisms (15 papers), Fibroblast Growth Factor Research (13 papers) and Peroxisome Proliferator-Activated Receptors (12 papers). The work is most often cited by research in Aging (620 citations), Endocrine and Autonomic Systems (2.2k citations), Physiology (5.2k citations), Molecular Biology (11.4k citations) and Endocrinology, Diabetes and Metabolism (2.0k citations). Michael Downes has collaborated with scholars based in United States, Australia and France. Frequent co-authors include Ronald M. Evans, Ruth T. Yu, Christopher Liddle, Annette R. Atkins, David J. Mangelsdorf, Nasun Hah, Angie L. Bookout, Grant D. Barish, Jae Myoung Suh and Maryam Ahmadian. Their work appears in journals such as Proceedings of the National Academy of Sciences, Cell Metabolism, Cell, Nature and Molecular Endocrinology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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