Mark E. B. Smith

8.2k citations

52 papers · 3.3k · h-index 34

Impact in

Organic Chemistry top 1%
- Click Chemistry and Applications
- Advanced Polymer Synthesis and Characterization
- Carbohydrate Chemistry and Synthesis
- Asymmetric Synthesis and Catalysis
- Sulfur-Based Synthesis Techniques
Radiology, Nuclear Medicine and Imaging top 2%
- Monoclonal and Polyclonal Antibodies Research

Papers in

Organic Chemistry 25
- Click Chemistry and Applications 16
- Asymmetric Synthesis and Catalysis 7
Molecular Biology 38
- Enzyme Catalysis and Immobilization 16
- Chemical Synthesis and Analysis 13
- Glycosylation and Glycoproteins Research 3
- Biochemical and Structural Characterization 3

Co-authors: Stephen Caddick (24 shared papers)James R. Baker (19 shared papers)Vijay Chudasama (17 shared papers)Helen C. Hailes (13 shared papers)John M. Ward (9 shared papers)Felix F. Schumacher (7 shared papers)Antoine Maruani (9 shared papers)Chris P. Ryan (6 shared papers)
Journals: Chemical Communications (7 papers)Organic & Biomolecular Chemistry (7 papers)Journal of the American Chemical Society (4 papers)Tetrahedron Letters (4 papers)Bioconjugate Chemistry (3 papers)
Partner nations: United Kingdom United States Denmark

In The Last Decade

Mark E. B. Smith

52 papers receiving 3.1k citations

Peers

Countries citing papers authored by Mark E. B. Smith

Since Specialization

Citations

This map shows the geographic impact of Mark E. B. Smith's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Mark E. B. Smith with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Mark E. B. Smith more than expected).

Fields of papers citing papers by Mark E. B. Smith

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Mark E. B. Smith. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Mark E. B. Smith. The network helps show where Mark E. B. Smith may publish in the future.

Co-authors

The 25 scholars most cited alongside Mark E. B. Smith, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Mark E. B. Smith Line = papers co-authored together Mark E. B. Smith links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

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#	Work
1	Protein Modification, Bioconjugation, and Disulfide Bridging Using Bromomaleimides Journal of the American Chemical Society ·Mark E. B. Smith, Felix F. Schumacher, Chris P. Ryan, Lauren M. Tedaldi, Danai Papaioannou, Gabriel Waksman, Stephen Caddick, James R. Baker	2010	339
2	Substrate spectrum of ω-transaminase from Chromobacterium violaceum DSM30191 and its potential for biocatalysis Enzyme and Microbial Technology ·Ursula Kaulmann, Kirsty Smithies, Mark E. B. Smith, Helen C. Hailes, John M. Ward	2007	279
3	A plug-and-play approach to antibody-based therapeutics via a chemoselective dual click strategy Nature Communications ·Antoine Maruani, Mark E. B. Smith, Enrique Miranda, Kerry Ann Chester, Vijay Chudasama, Stephen Caddick	2015	217
4	Next generation maleimides enable the controlled assembly of antibody–drug conjugates via native disulfide bond bridging Organic & Biomolecular Chemistry ·Felix F. Schumacher, João P. M. Nunes, Antoine Maruani, Vijay Chudasama, Mark E. B. Smith, Kerry Ann Chester, James R. Baker, Stephen Caddick	2014	144
5	In Situ Maleimide Bridging of Disulfides and a New Approach to Protein PEGylation Bioconjugate Chemistry ·Felix F. Schumacher, Muriel Nobles, Chris P. Ryan, Mark E. B. Smith, Andrew J. Tinker, Stephen Caddick, James R. Baker	2011	124
6	One‐pot synthesis of amino‐alcohols using a de‐novo transketolase and β‐alanine: Pyruvate transaminase pathway in Escherichia coli Biotechnology and Bioengineering ·Christine Ursula Ingram, Mark E. B. Smith, Paul A. Dalby, John M. Ward, Helen C. Hailes, Gary J. Lye +1 other	2006	122
7	Functional native disulfide bridging enables delivery of a potent, stable and targeted antibody–drug conjugate (ADC) Chemical Communications ·João P. M. Nunes, Maurício Morais, Vessela Vassileva, Vineeth S. Rajkumar, Mark E. B. Smith, R. Barbara Pedley, Stephen Caddick, James R. Baker	2015	106
8	Bromopyridazinedione-mediated protein and peptide bioconjugation Chemical Communications ·Vijay Chudasama, Mark E. B. Smith, Felix F. Schumacher, Danai Papaioannou, Gabriel Waksman, James R. Baker, Stephen Caddick	2011	101
9	Tunable reagents for multi-functional bioconjugation: reversible or permanent chemical modification of proteins and peptides by control of maleimide hydrolysis Chemical Communications ·Chris P. Ryan, Mark E. B. Smith, Felix F. Schumacher, Dina Grohmann, Danai Papaioannou, Gabriel Waksman, Finn Werner, James R. Baker	2011	99
10	Parallel Sheet Secondary Structure in γ-Peptides Journal of the American Chemical Society ·Matthew G. Woll, Jonathan R. Lai, Ilia A. Guzei, Stephen J. Taylor, Mark E. B. Smith, Samuel H. Gellman	2001	93
11	Bromomaleimides: new reagents for the selective and reversible modification of cysteine Chemical Communications ·Lauren M. Tedaldi, Mark E. B. Smith, Ramiz I. Nathani, James R. Baker	2009	91
12	A Multidisciplinary Approach Toward the Rapid and Preparative-Scale Biocatalytic Synthesis of Chiral Amino Alcohols: A Concise Transketolase-/ω-Transaminase-Mediated Synthesis of (2S,3S)-2-Aminopentane-1,3-diol Organic Process Research & Development ·Mark E. B. Smith, Binghui Chen, Edward G. Hibbert, Ursula Kaulmann, Kirsty Smithies, James L. Galman, Frank Baganz, Paul A. Dalby	2009	77
13	Directed evolution of transketolase activity on non-phosphorylated substrates Journal of Biotechnology ·Edward G. Hibbert, Tarik Senussi, Seán J. Costelloe, Wenling Lei, Mark E. B. Smith, John M. Ward, Helen C. Hailes, Paul A. Dalby	2007	70
14	Pyridazinediones deliver potent, stable, targeted and efficacious antibody–drug conjugates (ADCs) with a controlled loading of 4 drugs per antibody RSC Advances ·João P. M. Nunes, Vessela Vassileva, Antoine Maruani, João C. F. Nogueira, Mark E. B. Smith, R. Barbara Pedley, Stephen Caddick, James R. Baker	2017	69
15	Regioselective and Stoichiometrically Controlled Conjugation of Photodynamic Sensitizers to a HER2 Targeting Antibody Fragment Bioconjugate Chemistry ·Francesca Bryden, Antoine Maruani, Huguette Savoie, Vijay Chudasama, Mark E. B. Smith, Stephen Caddick, Ross W. Boyle	2014	68
16	Optimisation of the dibromomaleimide (DBM) platform for native antibody conjugation by accelerated post-conjugation hydrolysis Organic & Biomolecular Chemistry ·Maurício Morais, João P. M. Nunes, Kersti Karu, Nafsika Forte, Irene Benni, Mark E. B. Smith, Stephen Caddick, Vijay Chudasama	2017	66
17	Acid-cleavable thiomaleamic acid linker for homogeneous antibody–drug conjugation Chemical Communications ·Lourdes Castañeda, Antoine Maruani, Felix F. Schumacher, Enrique Miranda, Vijay Chudasama, Kerry Ann Chester, James R. Baker, Mark E. B. Smith	2013	64
18	Transketolase from Escherichia coli: A practical procedure for using the biocatalyst for asymmetric carbon-carbon bond synthesis Tetrahedron Asymmetry ·Mark E. B. Smith, Nicholas John Turner, MALCOLM D. LILLY, John M. Woodley +2 others	1996	63
19	Non-α-hydroxylated aldehydes with evolved transketolase enzymes Organic & Biomolecular Chemistry ·Armando Cázares‐Körner, James L. Galman, Lydia G. Crago, Mark E. B. Smith, John Strafford, Leonardo Rios‐Solis, Gary J. Lye, Paul A. Dalby	2010	62
20	Enhancing and Reversing the Stereoselectivity of Escherichia coli Transketolase via Single‐Point Mutations Advanced Synthesis & Catalysis ·Mark E. B. Smith, Edward G. Hibbert, Alexander B. Jones, Paul A. Dalby, Helen C. Hailes	2008	61

About Mark E. B. Smith

Mark E. B. Smith is a scholar working on Organic Chemistry, Molecular Biology, Radiology, Nuclear Medicine and Imaging, Biochemistry and Developmental Neuroscience, having authored 52 papers that have together received 3.3k indexed citations. Recurring topics across this work include Click Chemistry and Applications (16 papers), Enzyme Catalysis and Immobilization (16 papers), Chemical Synthesis and Analysis (13 papers), Monoclonal and Polyclonal Antibodies Research (11 papers), Asymmetric Synthesis and Catalysis (7 papers), Glycosylation and Glycoproteins Research (3 papers), Biochemical and Structural Characterization (3 papers) and Photodynamic Therapy Research Studies (2 papers). The work is most often cited by research in Organic Chemistry (1.4k citations), Radiology, Nuclear Medicine and Imaging (637 citations), Molecular Biology (1.7k citations), Biochemistry (101 citations) and Biomaterials (118 citations). Mark E. B. Smith has collaborated with scholars based in United Kingdom, United States and Denmark. Frequent co-authors include Stephen Caddick, James R. Baker, Vijay Chudasama, Helen C. Hailes, John M. Ward, Felix F. Schumacher, Antoine Maruani, Chris P. Ryan, Ursula Kaulmann and Kerry Ann Chester. Their work appears in journals such as Chemical Communications, Organic & Biomolecular Chemistry, Journal of the American Chemical Society, Tetrahedron Letters and Bioconjugate Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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