Mark E. B. Smith

8.5k citations

98 papers · 4.0k · h-index 39

Impact in

Biochemistry top 0.5%
Organic Chemistry top 1%
- Click Chemistry and Applications
- Carbohydrate Chemistry and Synthesis

Papers in

Molecular Biology 49
- Chemical Synthesis and Analysis 18
- Enzyme Catalysis and Immobilization 11
- Microbial Metabolic Engineering and Bioproduction 10
Organic Chemistry 28
- Click Chemistry and Applications 11

Co-authors: Stephen Caddick (24 shared papers)James R. Baker (19 shared papers)Vijay Chudasama (17 shared papers)John M. Ward (9 shared papers)Felix Schumacher (7 shared papers)Antoine Maruani (9 shared papers)Chris P. Ryan (6 shared papers)Ursula Kaulmann (4 shared papers)
Journals: Organic & Biomolecular Chemistry (9 papers)Chemical Communications (7 papers)Tetrahedron Letters (5 papers)Journal of the American Chemical Society (4 papers)Tetrahedron Asymmetry (3 papers)
Partner nations: United Kingdom United States India

In The Last Decade

Mark E. B. Smith

95 papers receiving 3.9k citations

Peers

Countries citing papers authored by Mark E. B. Smith

Since Specialization

Citations

This map shows the geographic impact of Mark E. B. Smith's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Mark E. B. Smith with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Mark E. B. Smith more than expected).

Fields of papers citing papers by Mark E. B. Smith

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Mark E. B. Smith. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Mark E. B. Smith. The network helps show where Mark E. B. Smith may publish in the future.

Co-authors

The 25 scholars most cited alongside Mark E. B. Smith, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Mark E. B. Smith Line = papers co-authored together Mark E. B. Smith links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 98 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Protein Modification, Bioconjugation, and Disulfide Bridging Using Bromomaleimides Journal of the American Chemical Society ·Mark E. B. Smith, Felix Schumacher, Chris P. Ryan, Lauren Tedaldi, Danai Papaioannou, Gabriel Waksman, Stephen Caddick, James R. Baker	2010	330
2	Substrate spectrum of ω-transaminase from Chromobacterium violaceum DSM30191 and its potential for biocatalysis Enzyme and Microbial Technology ·Ursula Kaulmann, Kirsty Smithies, Mark E. B. Smith, (unknown), John M. Ward	2007	275
3	A plug-and-play approach to antibody-based therapeutics via a chemoselective dual click strategy Nature Communications ·Antoine Maruani, Mark E. B. Smith, Enrique Miranda, Kerry Chester, Vijay Chudasama, Stephen Caddick	2015	211
4	Next generation maleimides enable the controlled assembly of antibody–drug conjugatesvianative disulfide bond bridging Organic & Biomolecular Chemistry ·Felix Schumacher, João P. M. Nunes, Antoine Maruani, Vijay Chudasama, Mark E. B. Smith, Kerry Chester, James R. Baker, Stephen Caddick	2014	137
5	One‐pot synthesis of amino‐alcohols using a de‐novo transketolase and β‐alanine: Pyruvate transaminase pathway in Escherichia coli Biotechnology and Bioengineering ·Christine Ursula Ingram, Martin Bommer, Mark E. B. Smith, Paul A. Dalby, John M. Ward, (unknown), Gary J. Lye	2006	122
6	In Situ Maleimide Bridging of Disulfides and a New Approach to Protein PEGylation Bioconjugate Chemistry ·Felix Schumacher, Muriel Nobles, Chris P. Ryan, Mark E. B. Smith, Andrew Tinker, Stephen Caddick, James R. Baker	2011	119
7	Iron versus Ruthenium: Dramatic Changes in Electronic Structure Result from Replacement of One Fe by Ru in [{Cp(dppe)Fe}-CC-CC-{Fe(dppe)Cp}]ⁿ⁺(n= 0, 1, 2) Organometallics ·Michael I. Bruce, Karine Costuas, Thomas Davin, Benjamin G. Ellis, Jean‐François Halet, Claude Lapinte, Paul J. Low, Mark E. B. Smith, Brian W. Skelton, Loı̈c Toupet, Allan H. White	2005	109
8	Functional native disulfide bridging enables delivery of a potent, stable and targeted antibody–drug conjugate (ADC) Chemical Communications ·João P. M. Nunes, Maurício Morais, Vessela Vassileva, E. Robinson, Vineeth Rajkumar, Mark E. B. Smith, R. Barbara Pedley, Stephen Caddick, James R. Baker, Vijay Chudasama	2015	103
9	Bromopyridazinedione-mediated protein and peptide bioconjugation Chemical Communications ·Vijay Chudasama, Mark E. B. Smith, Felix Schumacher, Danai Papaioannou, Gabriel Waksman, James R. Baker, Stephen Caddick	2011	96
10	Recent Advances in the Chemical Synthesis and Evaluation of Anticancer Nucleoside Analogues Molecules ·Mieke Guinan, Caecilie M. M. Benckendorff, Mark E. B. Smith, Gavin J. Miller	2020	95
11	Tunable reagents for multi-functional bioconjugation: reversible or permanent chemical modification of proteins and peptides by control of maleimide hydrolysis Chemical Communications ·Chris P. Ryan, Mark E. B. Smith, Felix Schumacher, Dina Grohmann, Danai Papaioannou, Gabriel Waksman, Finn Werner, James R. Baker, Stephen Caddick	2011	94
12	Parallel Sheet Secondary Structure in γ-Peptides Journal of the American Chemical Society ·Matthew G. Woll, Jonathan R. Lai, Ilia A. Guzei, Stephen J. Taylor, Mark E. B. Smith, Samuel H. Gellman	2001	93
13	Bromomaleimides: new reagents for the selective and reversible modification of cysteine Chemical Communications ·Lauren Tedaldi, Mark E. B. Smith, Ramiz I. Nathani, James R. Baker	2009	89
14	A Multidisciplinary Approach Toward the Rapid and Preparative-Scale Biocatalytic Synthesis of Chiral Amino Alcohols: A Concise Transketolase-/ω-Transaminase-Mediated Synthesis of (2S,3S)-2-Aminopentane-1,3-diol Organic Process Research & Development ·Mark E. B. Smith, Bing Hui Chen, Edward G. Hibbert, Ursula Kaulmann, Kirsty Smithies, James L. Galman, Frank Baganz, Paul A. Dalby, (unknown), Gary J. Lye, John M. Ward, John M. Woodley, Martina Micheletti	2009	77
15	Directed evolution of transketolase activity on non-phosphorylated substrates Journal of Biotechnology ·Edward G. Hibbert, Tarik Senussi, Seán J. Costelloe, Wenling Lei, Mark E. B. Smith, John M. Ward, (unknown), Paul A. Dalby	2007	70
16	Regioselective and Stoichiometrically Controlled Conjugation of Photodynamic Sensitizers to a HER2 Targeting Antibody Fragment Bioconjugate Chemistry ·Francesca Bryden, Antoine Maruani, Huguette Savoie, Vijay Chudasama, Mark E. B. Smith, Stephen Caddick, Ross W. Boyle	2014	67
17	Pyridazinediones deliver potent, stable, targeted and efficacious antibody–drug conjugates (ADCs) with a controlled loading of 4 drugs per antibody RSC Advances ·E. Robinson, João P. M. Nunes, Vessela Vassileva, Antoine Maruani, João C. F. Nogueira, Mark E. B. Smith, R. Barbara Pedley, Stephen Caddick, James R. Baker, Vijay Chudasama	2017	66
18	Optimisation of the dibromomaleimide (DBM) platform for native antibody conjugation by accelerated post-conjugation hydrolysis Organic & Biomolecular Chemistry ·Maurício Morais, João P. M. Nunes, Kersti Karu, Nafsika Forte, Irene Benni, Mark E. B. Smith, Stephen Caddick, Vijay Chudasama, James R. Baker	2017	64
19	Acid-cleavable thiomaleamic acid linker for homogeneous antibody–drug conjugation Chemical Communications ·Lourdes Castañeda, Antoine Maruani, Felix Schumacher, Enrique Miranda, Vijay Chudasama, Kerry Chester, James R. Baker, Mark E. B. Smith, Stephen Caddick	2013	64
20	Transketolase from Escherichia coli: A practical procedure for using the biocatalyst for asymmetric carbon-carbon bond synthesis Tetrahedron Asymmetry ·Katie Morris, Mark E. B. Smith, Nicholas J. Turner, M. D. Lilly, Robin Mitra, John M. Woodley	1996	64

About Mark E. B. Smith

Mark E. B. Smith is a scholar working on Molecular Biology, Organic Chemistry, Oncology, Materials Chemistry and Radiology, Nuclear Medicine and Imaging, having authored 98 papers that have together received 4.0k indexed citations. Recurring topics across this work include Chemical Synthesis and Analysis (18 papers), Monoclonal and Polyclonal Antibodies Research (12 papers), Peptidase Inhibition and Analysis (12 papers), Biochemical Acid Research Studies (11 papers), Click Chemistry and Applications (11 papers), Enzyme Catalysis and Immobilization (11 papers), Microbial Metabolic Engineering and Bioproduction (10 papers) and HER2/EGFR in Cancer Research (9 papers). The work is most often cited by research in Biochemistry (470 citations), Organic Chemistry (1.8k citations), Radiology, Nuclear Medicine and Imaging (963 citations), Oncology (913 citations) and Molecular Biology (2.3k citations). Mark E. B. Smith has collaborated with scholars based in United Kingdom, United States and India. Frequent co-authors include Stephen Caddick, James R. Baker, Vijay Chudasama, John M. Ward, Felix Schumacher, Antoine Maruani, Chris P. Ryan, Ursula Kaulmann, Kirsty Smithies and Kerry Chester. Their work appears in journals such as Organic & Biomolecular Chemistry, Chemical Communications, Tetrahedron Letters, Journal of the American Chemical Society and Tetrahedron Asymmetry.

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Mark E. B. Smith

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