Mark Drost

613 citations

25 papers · 465 · h-index 12

Impact in

Pathology and Forensic Medicine top 5%
- Genetic factors in colorectal cancer
Cancer Research top 10%
- Cancer Genomics and Diagnostics

Papers in

Pathology and Forensic Medicine 18
- Genetic factors in colorectal cancer 18
Cancer Research 16
- Cancer Genomics and Diagnostics 16

Co-authors: Niels de Wind (17 shared papers)Lene Juel Rasmussen (7 shared papers)Robert M.W. Hofstra (3 shared papers)Sean V. Tavtigian (4 shared papers)José B.M. Zonneveld (3 shared papers)Hans Morreau (2 shared papers)Christopher D. Heinen (2 shared papers)Brigitte Royer‐Pokora (2 shared papers)
Journals: Human Mutation (8 papers)Prenatal Diagnosis (3 papers)European Journal of Human Genetics (2 papers)Genetics in Medicine (2 papers)Proceedings of the National Academy of Sciences (1 paper)
Partner nations: Netherlands Denmark Australia

In The Last Decade

Mark Drost

23 papers receiving 461 citations

Peers

Countries citing papers authored by Mark Drost

Since Specialization

Citations

This map shows the geographic impact of Mark Drost's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Mark Drost with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Mark Drost more than expected).

Fields of papers citing papers by Mark Drost

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Mark Drost. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Mark Drost. The network helps show where Mark Drost may publish in the future.

Co-authors

The 25 scholars most cited alongside Mark Drost, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Mark Drost Line = papers co-authored together Mark Drost links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 25 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Adjuvant Treatment for POLE Proofreading Domain–Mutant Cancers: Sensitivity to Radiotherapy, Chemotherapy, and Nucleoside Analogues Clinical Cancer Research ·Inge C. van Gool, Emily Rayner, Elisabeth M. Osse, Remi A. Nout, Carien L. Creutzberg, Ian P.M. Tomlinson, David N. Church, Vincent T.H.B.M. Smit	2018	62
2	Pathological assessment of mismatch repair gene variants in Lynch syndrome: Past, present, and future Human Mutation ·Lene Juel Rasmussen, Christopher D. Heinen, Brigitte Royer‐Pokora, Mark Drost, Sean V. Tavtigian, Robert M.W. Hofstra, Niels de Wind	2012	56
3	A cell-free assay for the functional analysis of variants of the mismatch repair protein MLH1 Human Mutation ·Mark Drost, Jos é B.M. Zonneveld, Linda van Dijk, Hans Morreau, Carli M.J. Tops, Hans F. A. Vasen, Juul Wijnen, Niels de Wind	2009	54
4	Comprehensive Mutation Analysis ofPMS2in a Large Cohort of Probands Suspected of Lynch Syndrome or Constitutional Mismatch Repair Deficiency Syndrome Human Mutation ·Heleen M. van der Klift, Arjen R. Mensenkamp, Mark Drost, Elsa C. Bik, Yvonne J. Vos, B. Redeker, Yvonne Tiersma, José B.M. Zonneveld	2016	51
5	A functional assay–based procedure to classify mismatch repair gene variants in Lynch syndrome Genetics in Medicine ·Mark Drost, Yvonne Tiersma, Bryony A. Thompson, Jane Hübertz Frederiksen, Guido Keijzers, Dylan M. Glubb, Scott D. Kathe, Jan Osinga	2018	45
6	A rapid and cell-free assay to test the activity of lynch syndrome-associated MSH2 and MSH6 missense variants Human Mutation ·Mark Drost, José B.M. Zonneveld, Sandrine van Hees, Lene Juel Rasmussen, Robert M.W. Hofstra, Niels de Wind	2011	40
7	Inactivation of DNA Mismatch Repair by Variants of Uncertain Significance in the PMS2 Gene Human Mutation ·Mark Drost, Hester Koppejan, Niels de Wind	2013	28
8	Two integrated and highly predictive functional analysis-based procedures for the classification of MSH6 variants in Lynch syndrome Genetics in Medicine ·Mark Drost, Yvonne Tiersma, Dylan M. Glubb, Scott D. Kathe, Sandrine van Hees, Fabienne M.G.R. Calléja, José B.M. Zonneveld, Kenneth Michael Boucher	2020	21
9	Genetic screens to identify pathogenic gene variants in the common cancer predisposition Lynch syndrome Proceedings of the National Academy of Sciences ·Mark Drost, Anne Lützen, Sandrine van Hees, Daniel Alexandre Ferreira, Fabienne M.G.R. Calléja, José B.M. Zonneveld, Finn Cilius Nielsen, Lene Juel Rasmussen	2013	18
10	Functional characterization of MLH1 missense variants identified in lynch syndrome patients Human Mutation ·Sofie Dabros Andersen, Sascha Emilie Liberti, Anne Lützen, Mark Drost, Inge Bernstein, Mef Christina Nilbert, Mev Dominguez–Valentin, Minna Nyström	2012	18
11	Contribution of mRNA Splicing to Mismatch Repair Gene Sequence Variant Interpretation Frontiers in Genetics ·Bryony A. Thompson, Rhiannon Walters, Michael T. Parsons, Troy D. Dumenil, Mark Drost, Yvonne Tiersma, Noralane M. Lindor, Sean V. Tavtigian	2020	17
12	Consequences of germline variation disrupting the constitutional translational initiation codon start sites of MLH1 and BRCA2 : Use of potential alternative start sites and implications for predicting variant pathogenicity Molecular Carcinogenesis ·Michael T. Parsons, Phillip J Whiley, Jonathan Beesley, Mark Drost, Niels de Wind, Bryony A. Thompson, Louise Marquart, John Llewelyn Hopper	2013	14
13	Digenic inheritance of MSH6 and MUTYH variants in familial colorectal cancer Genes Chromosomes and Cancer ·Stephanie A Schubert, Dina Ruano, Yvonne Tiersma, Mark Drost, Niels de Wind, Maartje Nielsen, Liselotte van Hest, Hans Morreau	2020	11
14	Predictive functional assay‐based classification of PMS2 variants in Lynch syndrome Human Mutation ·Emily Rayner, Yvonne Tiersma, Cristina Fortuño, Sandrine van Hees‐Stuivenberg, Mark Drost, Bryony A. Thompson, Amanda B. Spurdle, Niels de Wind	2022	7
15	DNA mismatch repair: from biophysics to bedside DNA repair ·Joyce H.G. Lebbink, Mark Drost, Niels de Wind	2015	5
16	Induction of mismatch repair deficiency, compromised DNA damage signaling and compound hypermutagenesis by a dietary mutagen in a cell-based model for Lynch syndrome Carcinogenesis ·Robbert Ijsselsteijn, Sandrine van Hees, Mark Drost, Jacob G. Jansen, Niels de Wind	2021	5
17	The High Diagnostic Yield of Prenatal Exome Sequencing Followed by 3400 Gene Panel Analysis in 629 Ongoing Pregnancies With Ultrasound Anomalies Prenatal Diagnosis ·Karin E. M. Diderich, Hennie T. Brüggenwirth, Marieke Joosten, Florentine F. Thurik, Jona Mijalkovic, MARIKE G. POLAK, Joan N. R. Kromosoeto, Galhana M. Somers‐Bolman	2024	4
18	Multivariate analysis of MLH1 c.1664T>C (p.Leu555Pro) mismatch repair gene variant demonstrates its pathogenicity Familial Cancer ·Michael Farrell, David John Hughes, Mark Drost, Andrew J. Wallace, Robert Cummins, Tracy A. Fletcher, Marie Meany, Elaine Williamson Kay	2013	3
19	Routine RNA-based analysis of potential splicing variants facilitates genomic diagnostics and reveals limitations of in silico prediction tools Human Genetics and Genomics Advances ·Mark Drost, Jordy Dekker, Federico Ferraro, Esmee Kasteleijn, Hannie Douben, Leontine van Unen, Marianne Hoogeveen‐Westerveld, Peter Elfferich	2025	1
20	Response to: Design of a Core Classification Process for DNA Mismatch Repair Variations of A Priori Unknown Functional Significance Human Mutation ·Lene Juel Rasmussen, Christopher D. Heinen, Brigitte Royer‐Pokora, Mark Drost, Sean V. Tavtigian, Robert M.W. Hofstra, Niels de Wind	2013	1

About Mark Drost

Mark Drost is a scholar working on Pathology and Forensic Medicine, Cancer Research, Genetics, Molecular Biology and Pediatrics, Perinatology and Child Health, having authored 25 papers that have together received 465 indexed citations. Recurring topics across this work include Genetic factors in colorectal cancer (18 papers), Cancer Genomics and Diagnostics (16 papers), Genomics and Rare Diseases (6 papers), RNA Research and Splicing (5 papers), DNA Repair Mechanisms (3 papers), Prenatal Screening and Diagnostics (2 papers), Genetics and Neurodevelopmental Disorders (1 paper) and RNA modifications and cancer (1 paper). The work is most often cited by research in Pathology and Forensic Medicine (321 citations), Cancer Research (195 citations), Obstetrics and Gynecology (51 citations), Genetics (121 citations) and Reproductive Medicine (24 citations). Mark Drost has collaborated with scholars based in Netherlands, Denmark and Australia. Frequent co-authors include Niels de Wind, Lene Juel Rasmussen, Robert M.W. Hofstra, Sean V. Tavtigian, José B.M. Zonneveld, Hans Morreau, Christopher D. Heinen, Brigitte Royer‐Pokora, Carli M.J. Tops and Linda van Dijk. Their work appears in journals such as Human Mutation, Prenatal Diagnosis, European Journal of Human Genetics, Genetics in Medicine and Proceedings of the National Academy of Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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