Mark A. Smith

10.1k citations

66 papers · 7.7k · 4 hit papers · h-index 35

Impact in

Biological Psychiatry top 1%
Physiology top 0.5%
- Alzheimer's disease research and treatments

Papers in

Molecular Biology 29
- DNA Repair Mechanisms 3
Physiology 22
- Alzheimer's disease research and treatments 20

Co-authors: George Perry (21 shared papers)Lawrence M. Sayre (3 shared papers)Joseph S. Beckman (1 shared paper)Akihiko Nunomura (4 shared papers)Peggy L.R. Harris (3 shared papers)Robert G. Salomon (1 shared paper)Mary C. Beckerle (12 shared papers)Gjumrakch Aliev (3 shared papers)
Journals: Proceedings of the National Academy of Sciences (4 papers)CNS & Neurological Disorders - Drug Targets (3 papers)PLoS ONE (3 papers)Genetics (2 papers)Current Alzheimer Research (2 papers)
Partner nations: United States Japan Canada

In The Last Decade

Mark A. Smith

66 papers receiving 7.5k citations

Mark A. Smith's Hit Papers

align trajectories log scale

Oxidative Damage Is the Earliest Event in Alzheimer Disease 2001 · 1.6k citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2001 Journal of Neuropathology & Experimental Neurology
2001 Cell
1997 Journal of Neuroscience
1997 Journal of Neurochemistry

Peers

Countries citing papers authored by Mark A. Smith

Since Specialization

Citations

This map shows the geographic impact of Mark A. Smith's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Mark A. Smith with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Mark A. Smith more than expected).

Fields of papers citing papers by Mark A. Smith

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Mark A. Smith. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Mark A. Smith. The network helps show where Mark A. Smith may publish in the future.

Co-authors

The 25 scholars most cited alongside Mark A. Smith, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Mark A. Smith Line = papers co-authored together Mark A. Smith links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 66 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Oxidative Damage Is the Earliest Event in Alzheimer Disease Journal of Neuropathology & Experimental Neurology ·Akihiko Nunomura, George Perry, Gjumrakch Aliev, Keisuke Hirai, Atsushi Takeda, Elizabeth K. Balraj, Paul K. Jones, Hossein Ghanbari, Takafumi Wataya, Shun Shimohama, Shigeru Chiba, Craig Atwood, Robert B. Petersen, Mark A. Smith Hit paper breakdown →	2001	1610
2	Widespread Peroxynitrite-Mediated Damage in Alzheimer’s Disease Journal of Neuroscience ·Mark A. Smith, Peggy L. Richey Harris, Lawrence M. Sayre, Joseph S. Beckman, George Perry Hit paper breakdown →	1997	1125
3	4‐Hydroxynonenal‐Derived Advanced Lipid Peroxidation End Products Are Increased in Alzheimer's Disease Journal of Neurochemistry ·Lawrence M. Sayre, Dawn A. Zelasko, Peggy L.R. Harris, George Perry, Robert G. Salomon, Mark A. Smith Hit paper breakdown →	1997	908
4	Drosophila Fragile X-Related Gene Regulates the MAP1B Homolog Futsch to Control Synaptic Structure and Function Cell ·Yongqing Zhang, Adina Bailey, H Matthies, Robert Renden, Mark A. Smith, Sean D. Speese, Gerald M. Rubin, Kendal Broadie Hit paper breakdown →	2001	563
5	Dorsoventral Patterning in Hemichordates: Insights into Early Chordate Evolution PLoS Biology ·Christopher J. Lowe, Mark Terasaki, Michael Wu, Robert M. Freeman, Linda L. Runft, Kristen M. Kwan, Saori L. Haigo, Jochanan Aronowicz, Eric S. Lander, Chris Gruber, Mark A. Smith, Marc W. Kirschner, John C. Gerhart	2006	303
6	Oxidative Stress Signaling in Alzheimers Disease Current Alzheimer Research ·Bo Su, Xinglong Wang, Akihiko Nunomura, Paula I. Moreira, Hyoung‐gon Lee, George Perry, Mark A. Smith, Xiongwei Zhu	2008	284
7	A Zyxin-Mediated Mechanism for Actin Stress Fiber Maintenance and Repair Developmental Cell ·Mark A. Smith, Elizabeth Blankman, Margaret L. Gardel, Laura Luettjohann, Clare M. Waterman, Mary C. Beckerle	2010	186
8	Loss of heterozygosity suggests tumor suppressor gene responsible for primary hepatocellular carcinoma. Proceedings of the National Academy of Sciences ·Kenneth H. Buetow, J.C. Murray, Jonathan Israel, William T. London, Mark A. Smith, M C Kew, Véronique Blanquet, Christian Bréchot, AG Redeker, S. Govindarajah	1989	177
9	4-Oxo-2-nonenal Is Both More Neurotoxic and More Protein Reactive than 4-Hydroxy-2-nonenal Chemical Research in Toxicology ·De Lin, Hyoung‐gon Lee, Quan Liu, George Perry, Mark A. Smith, Lawrence M. Sayre	2005	145
10	Alzheimer Disease and the Role of Free Radicals in the Pathogenesis of the Disease CNS & Neurological Disorders - Drug Targets ·George Perry, Paula I. Moreira, Maria S. Santos, Catarina R. Oliveira, Justin Shenk, Akihiko Nunomura, Mark A. Smith, Xiongwei Zhu	2008	139
11	Cyclin' toward dementia Journal of Neuroscience Research ·Arun K. Raina, Xiongwei Zhu, Catherine A. Rottkamp, Mervyn J. Monteiro, Atsushi Takeda, Mark A. Smith	2000	134
12	Extracellular neurofibrillary tangles reflect neuronal loss and provide further evidence of extensive protein cross-linking in Alzheimer disease Acta Neuropathologica ·Patrick Cras, Mark A. Smith, Peggy L. Richey, Sandra L. Siedlak, Paul Mulvihill, George Perry	1995	131
13	Neuronal Death and Survival Under Oxidative Stress in Alzheimer and Parkinson Diseases CNS & Neurological Disorders - Drug Targets ·Akihiko Nunomura, Paula I. Moreira, Hyoung‐gon Lee, Xiaochun Zhu, Rudy J. Castellani, Mark A. Smith, George Perry	2007	123
14	LIM proteins in actin cytoskeleton mechanoresponse Trends in Cell Biology ·Mark A. Smith, Laura Hoffman, Mary C. Beckerle	2014	101
15	Mechanosensing through Direct Binding of Tensed F-Actin by LIM Domains Developmental Cell ·Xiaoyu Sun, Donovan Y.Z. Phua, Lucas Axiotakis, Mark A. Smith, Elizabeth Blankman, Rui Gong, Robert C. Cail, Santiago Espinosa de los Reyes, Mary C. Beckerle, Clare M. Waterman, Gregory M. Alushin	2020	100
16	NMR Studies of Zinc, Copper, and Iron Binding to Histidine, the Principal Metal Ion Complexing Site of Amyloid-β Peptide Journal of Alzheimer s Disease ·Nanditha G. Nair, George Perry, Mark A. Smith, V. Prakash Reddy	2010	98
17	Mitochondria and vascular lesions as a central target for the development of Alzheimer's disease and Alzheimer disease-like pathology in transgenic mice Neurological Research ·Gjumrakch Aliev, Dilara Seyidova, Bruce T. Lamb, Mark E. Obrenovich, Sandra L. Siedlak, Harry V. Vinters, Robert P. Friedland, Joseph C. LaManna, Mark A. Smith, George Perry	2003	82
18	Apoptosis in Alzheimer Disease: A Mathematical Improbability Current Alzheimer Research ·Xiongwei Zhu, Arun K. Raina, George Perry, Mark A. Smith	2006	80
19	The integrin effector PINCH regulates JNK activity and epithelial migration in concert with Ras suppressor 1 The Journal of Cell Biology ·Julie L. Kadrmas, Mark A. Smith, Kathleen A. Clark, Stephen M. Pronovost, Nemone Muster, John R. Yates, Mary C. Beckerle	2004	76
20	Low frequency of p53 mutations observed in a diverse collection of primary hepatocellular carcinomas. Proceedings of the National Academy of Sciences ·Kenneth H. Buetow, Val C. Sheffield, Min Zhu, Tianlun Zhou, Fu Shen, Okio Hino, Mark A. Smith, Brian J. McMahon, A Lanier, William T. London	1992	75

About Mark A. Smith

Mark A. Smith is a scholar working on Molecular Biology, Physiology, Cell Biology, Cellular and Molecular Neuroscience and Genetics, having authored 66 papers that have together received 7.7k indexed citations. Recurring topics across this work include Alzheimer's disease research and treatments (20 papers), Cellular Mechanics and Interactions (8 papers), Cholinesterase and Neurodegenerative Diseases (5 papers), Force Microscopy Techniques and Applications (4 papers), Cancer-related Molecular Pathways (4 papers), Trace Elements in Health (4 papers), DNA Repair Mechanisms (3 papers) and Microtubule and mitosis dynamics (3 papers). The work is most often cited by research in Biological Psychiatry (333 citations), Physiology (3.2k citations), Neurology (808 citations), Biochemistry (444 citations) and Pharmacology (918 citations). Mark A. Smith has collaborated with scholars based in United States, Japan and Canada. Frequent co-authors include George Perry, Lawrence M. Sayre, Joseph S. Beckman, Akihiko Nunomura, Peggy L.R. Harris, Robert G. Salomon, Mary C. Beckerle, Gjumrakch Aliev, Atsushi Takeda and Robert B. Petersen. Their work appears in journals such as Proceedings of the National Academy of Sciences, CNS & Neurological Disorders - Drug Targets, PLoS ONE, Genetics and Current Alzheimer Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Mark A. Smith

Mark A. Smith's Hit Papers

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Fields of papers citing papers by Mark A. Smith

All Works

About Mark A. Smith

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