Lukas E. Dow

12.2k citations

77 papers · 6.3k · 4 hit papers · h-index 38

Impact in

Aging top 2%
Molecular Biology top 1%
- CRISPR and Genetic Engineering
- Wnt/β-catenin signaling in development and cancer
- RNA Interference and Gene Delivery
- Cancer-related gene regulation

Papers in

Molecular Biology 61
- CRISPR and Genetic Engineering 27
- Wnt/β-catenin signaling in development and cancer 11
- RNA Interference and Gene Delivery 9
- Advanced biosensing and bioanalysis techniques 7
Genetics 18
- Virus-based gene therapy research 7

Co-authors: Scott W. Lowe (29 shared papers)Patrick O. Humbert (8 shared papers)Emma M. Schatoff (13 shared papers)Kevin P. O’Rourke (7 shared papers)Darjus F. Tschaharganeh (6 shared papers)Alyna Katti (7 shared papers)Benjamin I. Leach (4 shared papers)Sarah M. Russell (4 shared papers)
Journals: Cancer Research (5 papers)Nature Biotechnology (5 papers)Cancer Discovery (5 papers)Oncogene (4 papers)Cell Reports (4 papers)
Partner nations: United States Australia Germany

In The Last Decade

Lukas E. Dow

72 papers receiving 6.2k citations

Lukas E. Dow's Hit Papers

align trajectories log scale

CRISPR in cancer biology and therapy 2022 · 310 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2022 Nature reviews. Cancer
2021 Nature
2015 Cell
2015 Science

Peers

Countries citing papers authored by Lukas E. Dow

Since Specialization

Citations

This map shows the geographic impact of Lukas E. Dow's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lukas E. Dow with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lukas E. Dow more than expected).

Fields of papers citing papers by Lukas E. Dow

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lukas E. Dow. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lukas E. Dow. The network helps show where Lukas E. Dow may publish in the future.

Co-authors

The 25 scholars most cited alongside Lukas E. Dow, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Lukas E. Dow Line = papers co-authored together Lukas E. Dow links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 77 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH Science ·Jihye Yun, Edouard Mullarky, Changyuan Lu, Kaitlyn Bosch, Adam Kavalier, Keith Rivera, Jatin Roper, Iok In Christine Chio, Ευγενία Γιαννοπούλου, Carlo Rago, Ashlesha Muley, John M. Asara, Jihye Paik, Olivier Elemento, Zhengming Chen, Darryl Pappin, Lukas E. Dow, Nickolas Papadopoulos, Steven S. Gross, Lewis C. Cantley Hit paper breakdown →	2015	741
2	Apc Restoration Promotes Cellular Differentiation and Reestablishes Crypt Homeostasis in Colorectal Cancer Cell ·Lukas E. Dow, Kevin P. O’Rourke, Janelle Simon, Darjus F. Tschaharganeh, Johan H. van Es, Hans Clevers, Scott W. Lowe Hit paper breakdown →	2015	412
3	Inducible in vivo genome editing with CRISPR-Cas9 Nature Biotechnology ·Lukas E. Dow, Jonathan Fisher, Kevin P. O’Rourke, Ashlesha Muley, Edward R. Kastenhuber, Geulah Livshits, Darjus F. Tschaharganeh, Nicholas D. Socci, Scott W. Lowe	2015	404
4	CRISPR in cancer biology and therapy Nature reviews. Cancer ·Alyna Katti, Bianca J. Diaz, Christina M. Caragine, Neville E. Sanjana, Lukas E. Dow Hit paper breakdown →	2022	310
5	Optimized base editors enable efficient editing in cells, organoids and mice Nature Biotechnology ·María Paz Zafra, Emma M. Schatoff, Alyna Katti, Miguel Foronda, Marco Breinig, Anabel Y. Schweitzer, Amber Simon, Teng Han, Sukanya Goswami, Emma Montgomery, Jordana K. Thibado, Edward R. Kastenhuber, Francisco J. Sánchez‐Rivera, Junwei Shi, Christopher R. Vakoc, Scott W. Lowe, Darjus F. Tschaharganeh, Lukas E. Dow	2018	262
6	A Rapid and Scalable System for Studying Gene Function in Mice Using Conditional RNA Interference Cell ·Prem K. Premsrirut, Lukas E. Dow, Sang Yong Kim, Matthew Camiolo, Colin D. Malone, Cornelius Miething, Claudio Scuoppo, Johannes Zuber, Ross A. Dickins, Scott C. Kogan, Kenneth R. Shroyer, Raffaella Sordella, Gregory J. Hannon, Scott W. Lowe	2011	244
7	WNT Signaling and Colorectal Cancer Current Colorectal Cancer Reports ·Emma M. Schatoff, Benjamin I. Leach, Lukas E. Dow	2017	236
8	Genetic Liver-Specific AMPK Activation Protects against Diet-Induced Obesity and NAFLD Cell Reports ·Daniel Garcia, Kristina Hellberg, Amandine Chaix, Martina Wallace, Sébastien Herzig, Mehmet G. Badur, Terry Lin, Maxim N. Shokhirev, Antônio F. M. Pinto, Debbie S. Ross, Alan Saghatelian, Satchidananda Panda, Lukas E. Dow, Christian M. Metallo, Reuben J. Shaw	2019	235
9	A Network of PDZ-Containing Proteins Regulates T Cell Polarity and Morphology during Migration and Immunological Synapse Formation Immunity ·Mandy Ludford‐Menting, Jane Oliaro, Faruk Sacirbegovic, Eric T.-Y. Cheah, Natalie Pedersen, Suzanne J. Thomas, Anupama Pasam, Rosa M. Iazzolino, Lukas E. Dow, Nigel J. Waterhouse, Amanda J. Murphy, Sarah Ellis, Mark J. Smyth, Michael H. Kershaw, Phillip K. Darcy, Patrick O. Humbert, Sarah M. Russell	2005	220
10	Dietary fructose improves intestinal cell survival and nutrient absorption Nature ·Samuel Taylor, Shakti Ramsamooj, Roger J. Liang, Alyna Katti, Rita Pozovskiy, Neil Vasan, Seo‐Kyoung Hwang, Navid Nahiyaan, Nancy Francoeur, Emma M. Schatoff, Jared L. Johnson, Manish A. Shah, Andrew J. Dannenberg, Robert Sebra, Lukas E. Dow, Lewis C. Cantley, Kyu Y. Rhee, Marcus D. Goncalves Hit paper breakdown →	2021	208
11	Toolkit for evaluating genes required for proliferation and survival using tetracycline-regulated RNAi Nature Biotechnology ·Johannes Zuber, Katherine McJunkin, Christof Fellmann, Lukas E. Dow, Meredith J. Taylor, Gregory J. Hannon, Scott W. Lowe	2010	197
12	Transplantation of engineered organoids enables rapid generation of metastatic mouse models of colorectal cancer Nature Biotechnology ·Kevin P. O’Rourke, Evangelia Loizou, Geulah Livshits, Emma M. Schatoff, Timour Baslan, Eusebio Manchado, Janelle Simon, Paul B. Romesser, Benjamin I. Leach, Teng Han, Chantal Pauli, Himisha Beltran, Mark A. Rubin, Lukas E. Dow, Scott W. Lowe	2017	180
13	The tumour-suppressor Scribble dictates cell polarity during directed epithelial migration: regulation of Rho GTPase recruitment to the leading edge Oncogene ·Lukas E. Dow, Jeffrey S. Kauffman, Jacinta Caddy, Andrew S. Peterson, Stephen M. Jane, Sarah M. Russell, Patrick O. Humbert	2006	155
14	SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia Journal of Clinical Investigation ·Helen Pearson, Pedro A. Pérez–Mancera, Lukas E. Dow, (unknown), Pierre Tennstedt, Debora Bogani, Imogen Elsum, Andy Greenfield, David A. Tuveson, Ronald Simon, Patrick O. Humbert	2011	150
15	Adenine base editing in an adult mouse model of tyrosinaemia Nature Biomedical Engineering ·Chun‐Qing Song, Tingting Jiang, Michelle F. Richter, Luke H. Rhym, Luke W. Koblan, María Paz Zafra, Emma M. Schatoff, Jordan L. Doman, Yueying Cao, Lukas E. Dow, Lihua Julie Zhu, Daniel G. Anderson, David R. Liu, Hao Yin, Wen Xue	2019	148
16	Inducible In Vivo Silencing of Brd4 Identifies Potential Toxicities of Sustained BET Protein Inhibition Cell Reports ·Jessica E. Bolden, Nilgun Tasdemir, Lukas E. Dow, Johan H. van Es, John E. Wilkinson, Zhen Zhao, Hans Clevers, Scott W. Lowe	2014	145
17	Loss of human Scribble cooperates with H-Ras to promote cell invasion through deregulation of MAPK signalling Oncogene ·Lukas E. Dow, Imogen Elsum, Caroline King, Kathryn M. Kinross, Helena E. Richardson, Patrick O. Humbert	2008	141
18	An outbreak of viral gastroenteritis associated with consumption of sandwiches: implications for the control of transmission by food handlers Epidemiology and Infection ·Umesh D. Parashar, Lukas E. Dow, Rebecca L. Fankhauser, Charles D. Humphrey, Jacqueline Miller, Tamie Ando, Karen Stanley Williams, C. R. EDDY, Jacqueline S. Noel, Tim Ingram, Joseph Bresee, Stephan S. Monroe, Roger I. Glass	1998	135
19	The Scribble and Par complexes in polarity and migration: friends or foes? Trends in Cell Biology ·Patrick O. Humbert, Lukas E. Dow, Sarah M. Russell	2006	130
20	A pipeline for the generation of shRNA transgenic mice Nature Protocols ·Lukas E. Dow, Prem K. Premsrirut, Johannes Zuber, Christof Fellmann, Katherine McJunkin, Cornelius Miething, Youngkyu Park, Ross A. Dickins, Gregory J. Hannon, Scott W. Lowe	2012	123

About Lukas E. Dow

Lukas E. Dow is a scholar working on Molecular Biology, Genetics, Oncology, Cancer Research and Cell Biology, having authored 77 papers that have together received 6.3k indexed citations. Recurring topics across this work include CRISPR and Genetic Engineering (27 papers), Wnt/β-catenin signaling in development and cancer (11 papers), Cancer Cells and Metastasis (10 papers), RNA Interference and Gene Delivery (9 papers), Hippo pathway signaling and YAP/TAZ (7 papers), Advanced biosensing and bioanalysis techniques (7 papers), Virus-based gene therapy research (7 papers) and Cancer Genomics and Diagnostics (6 papers). The work is most often cited by research in Aging (117 citations), Molecular Biology (4.0k citations), Cancer Research (767 citations), Business and International Management (116 citations) and Cell Biology (807 citations). Lukas E. Dow has collaborated with scholars based in United States, Australia and Germany. Frequent co-authors include Scott W. Lowe, Patrick O. Humbert, Emma M. Schatoff, Kevin P. O’Rourke, Darjus F. Tschaharganeh, Alyna Katti, Benjamin I. Leach, Sarah M. Russell, Ashlesha Muley and Janelle Simon. Their work appears in journals such as Cancer Research, Nature Biotechnology, Cancer Discovery, Oncogene and Cell Reports.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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In The Last Decade

Lukas E. Dow

Lukas E. Dow's Hit Papers

Peers

Countries citing papers authored by Lukas E. Dow

Fields of papers citing papers by Lukas E. Dow

All Works

About Lukas E. Dow

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