Kyle W. Sloop

7.5k citations

90 papers · 5.3k · 4 hit papers · h-index 40

Impact in

Endocrinology, Diabetes and Metabolism top 0.2%
- Diabetes Treatment and Management
Endocrine and Autonomic Systems top 1%
- Regulation of Appetite and Obesity

Papers in

Endocrinology, Diabetes and Metabolism 57
- Diabetes Treatment and Management 47
- Growth Hormone and Insulin-like Growth Factors 7
Molecular Biology 44
- Receptor Mechanisms and Signaling 22
- Metabolism, Diabetes, and Cancer 7

Co-authors: Francis S. Willard (23 shared papers)Matthew P. Coghlan (4 shared papers)Ricardo J. Samms (7 shared papers)Aaron D. Showalter (25 shared papers)Simon J. Rhodes (14 shared papers)Lawrence J. Slieker (6 shared papers)Tamer Coşkun (13 shared papers)David A. D’Alessio (8 shared papers)
Journals: Diabetes (14 papers)Journal of Biological Chemistry (7 papers)Gene (5 papers)Molecular Metabolism (5 papers)Endocrinology (4 papers)
Partner nations: United States Canada Spain

In The Last Decade

Kyle W. Sloop

89 papers receiving 5.2k citations

Kyle W. Sloop's Hit Papers

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LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist for glycemic control and weight loss: From discovery to clinical proof of concept 2022 · 196 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2022 Cell Metabolism
2020 Trends in Endocrinology and Metabolism
2020 JCI Insight
2018 Molecular Metabolism

Peers

Countries citing papers authored by Kyle W. Sloop

Since Specialization

Citations

This map shows the geographic impact of Kyle W. Sloop's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Kyle W. Sloop with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Kyle W. Sloop more than expected).

Fields of papers citing papers by Kyle W. Sloop

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Kyle W. Sloop. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Kyle W. Sloop. The network helps show where Kyle W. Sloop may publish in the future.

Co-authors

The 25 scholars most cited alongside Kyle W. Sloop, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Kyle W. Sloop Line = papers co-authored together Kyle W. Sloop links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 90 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: From discovery to clinical proof of concept Molecular Metabolism ·Tamer Coşkun, Kyle W. Sloop, Corina Loghin, Jorge Alsina‐Fernandez, Shweta Urva, Krister Bokvist, Xuewei Cui, Daniel A. Briere, Over Cabrera, William C. Roell, Uma Kuchibhotla, Julie S. Moyers, Charles Benson, Ruth E. Gimeno, David A. D’Alessio, Axel Haupt Hit paper breakdown →	2018	638
2	Regulation of Expression of ob mRNA and Protein by Glucocorticoids and cAMP Journal of Biological Chemistry ·Lawrence J. Slieker, Kyle W. Sloop, Peggy L. Surface, Aidas Kriauciunas, Frank LaQuier, Joseph Manetta, Julie M Bue-Valleskey, Thomas W. Stephens	1996	425
3	Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist JCI Insight ·Francis S. Willard, Jonathan D. Douros, M Gabe, Aaron D. Showalter, David B. Wainscott, Todd M. Suter, Megan E. Capozzi, Wijnand J. C. van der Velden, Cynthia Stutsman, Guemalli R. Cardona, Shweta Urva, Paul J. Emmerson, Jens J. Holst, David A. D’Alessio, Matthew P. Coghlan, Mette M. Rosenkilde, Jonathan E. Campbell, Kyle W. Sloop Hit paper breakdown →	2020	340
4	How May GIP Enhance the Therapeutic Efficacy of GLP-1? Trends in Endocrinology and Metabolism ·Ricardo J. Samms, Matthew P. Coghlan, Kyle W. Sloop Hit paper breakdown →	2020	297
5	LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist for glycemic control and weight loss: From discovery to clinical proof of concept Cell Metabolism ·Tamer Coşkun, Shweta Urva, William C. Roell, Hongchang Qu, Corina Loghin, Julie S. Moyers, Libbey S. O’Farrell, Daniel A. Briere, Kyle W. Sloop, Melissa K. Thomas, Valentina Pirro, David B. Wainscott, Francis S. Willard, Matthew Abernathy, LaRonda L. Morford, Yu Du, Charles Benson, Ruth E. Gimeno, Axel Haupt, Zvonko Miličević Hit paper breakdown →	2022	196
6	The Furan Fatty Acid Metabolite CMPF Is Elevated in Diabetes and Induces β Cell Dysfunction Cell Metabolism ·Kacey J. Prentice, (unknown), Emma M. Allister, Ying Liu, Lucy S. Jun, Kyle W. Sloop, Alexandre B. Hardy, Li Wei, Weiping Jia, I. George Fantus, Douglas H. Sweet, Gary Sweeney, Ravi Retnakaran, Feihan F. Dai, Michael B. Wheeler	2014	133
7	Structural basis for GLP-1 receptor activation by LY3502970, an orally active nonpeptide agonist Proceedings of the National Academy of Sciences ·Takahiro Kawai, Bingfa Sun, Hitoshi Yoshino, Dan Feng, Yoshiyuki Suzuki, Masanori Fukazawa, Shunsuke Nagao, David B. Wainscott, Aaron D. Showalter, Brian A. Droz, Tong Sun Kobilka, Matthew P. Coghlan, Francis S. Willard, Yoshiki Kawabe, Brian K. Kobilka, Kyle W. Sloop	2020	132
8	Activation of the GLP-1 receptor by a non-peptidic agonist Nature ·Peishen Zhao, Yi-Lynn Liang, Matthew J. Belousoff, Giuseppe Deganutti, Madeleine M. Fletcher, Francis S. Willard, Michael G. Bell, Michael E. Christe, Kyle W. Sloop, Asuka Inoue, Tin T. Truong, Lachlan Clydesdale, Sebastian G. B. Furness, Arthur Christopoulos, Ming-Wei Wang, Laurence J. Miller, Christopher A. Reynolds, Radostin Danev, Patrick M. Sexton, Denise Wootten	2020	129
9	Novel Small Molecule Glucagon-Like Peptide-1 Receptor Agonist Stimulates Insulin Secretion in Rodents and From Human Islets Diabetes ·Kyle W. Sloop, Francis S. Willard, Martin Brenner, James Ficorilli, Kathleen M. Valasek, Aaron D. Showalter, Thomas B. Farb, Julia X.C. Cao, Amy L. Cox, M. Dodson Michael, Sonia Maria Gutierrez Sanfeliciano, Mark J. Tebbe, Michael J. Coghlan	2010	122
10	Reduction of Hepatic and Adipose Tissue Glucocorticoid Receptor Expression With Antisense Oligonucleotides Improves Hyperglycemia and Hyperlipidemia in Diabetic Rodents Without Causing Systemic Glucocorticoid Antagonism Diabetes ·Lynnetta M. Watts, Vara Prasad Manchem, Thomas A. Leedom, Amber L. Rivard, Robert A. McKay, Dingjiu Bao, Teri Neroladakis, Brett P. Monia, Diane Bodenmiller, Julia X.C. Cao, Hongyan Zhang, Amy L. Cox, Steven J. Jacobs, M. Dodson Michael, Kyle W. Sloop, Sanjay Bhanot	2005	111
11	Targeted suppression of an amyloidogenic transthyretin with antisense oligonucleotides Muscle & Nerve ·Merrill D. Benson, Barbara Kluve‐Beckerman, Steven R. Zeldenrust, Angela M. Siesky, Diane Bodenmiller, Aaron D. Showalter, Kyle W. Sloop	2006	110
12	Deficiency of Adiponectin Receptor 2 Reduces Diet-Induced Insulin Resistance but Promotes Type 2 Diabetes Endocrinology ·Yanfang Liu, M. Dodson Michael, Shera Kash, William R. Bensch, Brett P. Monia, Susan F. Murray, Keith A. Otto, Samreen K. Syed, Sanjay Bhanot, Kyle W. Sloop, John M. Sullivan, Anne Reifel‐Miller	2006	94
13	GIP mediates the incretin effect and glucose tolerance by dual actions on α cells and β cells Science Advances ·Kimberley El, Sarah M. Gray, Megan E. Capozzi, Emily R. Knuth, Enyou Jin, Berit Svendsen, Alexis L. Clifford, Jennifer Brown, Sara E. Encisco, Bryanna M. Chazotte, Kyle W. Sloop, Derek J. Nunez, Matthew J. Merrins, David A. D’Alessio, Jonathan E. Campbell	2021	93
14	Regulation of the Follicle-Stimulating Hormone β Gene by the LHX3 LIM-Homeodomain Transcription Factor Endocrinology ·Brooke E. West, Gretchen E. Parker, Jesse J. Savage, Parinda Kiratipranon, Katherine S. Toomey, Lisa R. Beach, Stephanie C. Colvin, Kyle W. Sloop, Simon J. Rhodes	2004	79
15	The incretin co-agonist tirzepatide requires GIPR for hormone secretion from human islets Nature Metabolism ·Kimberley El, Jonathan D. Douros, Francis S. Willard, Aaron Novikoff, Ashot Sargsyan, Diego Pérez–Tilve, David B. Wainscott, Bin Yang, A. Y. Chen, Donald Wothe, Callum Coupland, Mattias H. Tschöp, Brian Finan, David A. D’Alessio, Kyle W. Sloop, Timo D. Müller, Jonathan E. Campbell	2023	77
16	GLP-1 Receptor in Pancreatic α-Cells Regulates Glucagon Secretion in a Glucose-Dependent Bidirectional Manner Diabetes ·Yanqing Zhang, Keshab R. Parajuli, Genevieve E. Fava, R. C. Gupta, Weiwei Xu, Lauren U. Nguyen, Anadil F. Zakaria, Vivian Fonseca, Hongjun Wang, Franck Mauvais‐Jarvis, Kyle W. Sloop, Hongju Wu	2018	77
17	Protein expression of UCP3 differs between human type 1, type 2a, and type 2b fibers The FASEB Journal ·Matthijs K. C. Hesselink, H. A. Keizer, Lars B. Borghouts, Gert Schaart, C.F.P. Kornips, Lawrence J. Slieker, Kyle W. Sloop, Wim H. M. Saris, Patrick Schrauwen	2001	75
18	Uncoupling Protein 3 (UCP3) Stimulates Glucose Uptake in Muscle Cells through a Phosphoinositide 3-Kinase-dependent Mechanism Journal of Biological Chemistry ·Christine Huppertz, Britta Fischer, Young‐Bum Kim, Ko Kotani, Antonio Vidal‐Puig, Lawrence J. Slieker, Kyle W. Sloop, Bradford B. Lowell, Barbara B. Kahn	2001	73
19	Tirzepatide induces a thermogenic-like amino acid signature in brown adipose tissue Molecular Metabolism ·Ricardo J. Samms, Guofang Zhang, Wentao He, Olga Ilkayeva, Brian A. Droz, Steven M. Bauer, Cynthia Stutsman, Valentina Pirro, Kyla Collins, Ellen C Furber, Tamer Coşkun, Kyle W. Sloop, Joseph T. Brozinick, Christopher B. Newgard	2022	72
20	Structural insights into probe-dependent positive allosterism of the GLP-1 receptor Nature Chemical Biology ·Ana B. Bueno, Bingfa Sun, Francis S. Willard, Dan Feng, Joseph D. Ho, David B. Wainscott, Aaron D. Showalter, Michal Vieth, Qi Chen, Cynthia Stutsman, Betty Chau, James Ficorilli, Francisco J. Agejas, Graham R. Cumming, Alma Jiménez, I. Rojo, Tong Sun Kobilka, Brian K. Kobilka, Kyle W. Sloop	2020	71

About Kyle W. Sloop

Kyle W. Sloop is a scholar working on Endocrinology, Diabetes and Metabolism, Molecular Biology, Surgery, Cellular and Molecular Neuroscience and Genetics, having authored 90 papers that have together received 5.3k indexed citations. Recurring topics across this work include Diabetes Treatment and Management (47 papers), Pancreatic function and diabetes (26 papers), Receptor Mechanisms and Signaling (22 papers), Neuropeptides and Animal Physiology (14 papers), Adipose Tissue and Metabolism (9 papers), Regulation of Appetite and Obesity (8 papers), Metabolism, Diabetes, and Cancer (7 papers) and Growth Hormone and Insulin-like Growth Factors (7 papers). The work is most often cited by research in Endocrinology, Diabetes and Metabolism (2.5k citations), Endocrine and Autonomic Systems (634 citations), Physiology (1.0k citations), Cellular and Molecular Neuroscience (667 citations) and Pharmacology (571 citations). Kyle W. Sloop has collaborated with scholars based in United States, Canada and Spain. Frequent co-authors include Francis S. Willard, Matthew P. Coghlan, Ricardo J. Samms, Aaron D. Showalter, Simon J. Rhodes, Lawrence J. Slieker, Tamer Coşkun, David A. D’Alessio, Daniel A. Briere and Shweta Urva. Their work appears in journals such as Diabetes, Journal of Biological Chemistry, Gene, Molecular Metabolism and Endocrinology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Kyle W. Sloop

Kyle W. Sloop's Hit Papers

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