Junji Sagara

6.8k citations
68 papers · 5.8k · 2 hit papers · h-index 37

Impact in

  • Immunology top 1%
    • interferon and immune responses
    • Immune Response and Inflammation
    • IL-33, ST2, and ILC Pathways
  • Molecular Biology top 1%
    • Inflammasome and immune disorders
    • Cell death mechanisms and regulation
    • Heme Oxygenase-1 and Carbon Monoxide

Papers in

  • Molecular Biology 51
    • Inflammasome and immune disorders 24
    • Cell death mechanisms and regulation 14
    • Viral Infectious Diseases and Gene Expression in Insects 4
  • Immunology 23
    • Immune Response and Inflammation 13
    • interferon and immune responses 9
Co-authors
Shun’ichiro Taniguchi (34 shared papers)Junya Masumoto (14 shared papers)Akihiko Kawai (9 shared papers)Shöichiro Tsukita (5 shared papers)Kenichi Oishi (1 shared paper)N Sato (1 shared paper)Masafumi Takahashi (8 shared papers)Tetsuo Noda (7 shared papers)
Journals
The Journal of Immunology (5 papers)Biochemical and Biophysical Research Communications (5 papers)Journal of Biological Chemistry (4 papers)The Journal of Biochemistry (4 papers)The Journal of Cell Biology (3 papers)
Partner nations
JapanUnited StatesAustralia

In The Last Decade

Junji Sagara

68 papers receiving 5.7k citations

Junji Sagara's Hit Papers

Inflammasome Activation of Cardiac Fibroblasts Is Essential for Myocardial Ischemia/Reperfusion Injury 2011 · 721 citations
7210+10+21Years since publication200400600
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

  • it has ≥500 total citations;
  • it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
  • it reaches the top citation threshold in at least one of its specific research topics.
  1. 2011 Circulation
  2. 1994 The Journal of Cell Biology

Peers

Junji Sagara
Comparison fields: 5 of 116
  • Immunology 2.2k
  • Molecular Biology 4.3k
  • Immunology and Allergy 316
  • Nephrology 305
  • Cell Biology 678
Replace Westley H. Reeves with:
Westley H. Reeves United States
Bruno Luckow Germany
Peter J. Gough United States
Hisanori Umehara Japan
Geertrui Denecker Belgium
Ann Ranger United States
Kate E. Lawlor Australia
Merone Roose‐Girma United States
J Tschopp Switzerland
Gordon S. Duncan Canada
Junji Sagara relative to Westley H. Reeves United States Westley H. Reeves's profile →
Citations per field
00.5×2×2.5×
Westley H. Reeves · 1×
Citations per year

Countries citing papers authored by Junji Sagara

Since Specialization
Citations

This map shows the geographic impact of Junji Sagara's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Junji Sagara with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Junji Sagara more than expected).

Fields of papers citing papers by Junji Sagara

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Junji Sagara. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Junji Sagara. The network helps show where Junji Sagara may publish in the future.

Co-authors

The 25 scholars most cited alongside Junji Sagara, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Junji Sagara Line = papers co-authored together Junji Sagara links everyone, so they are left out of the graph.

All Works

20 of 20 papers shown

Showing the 20 most-cited of 68 papers — load more, or switch the sort, to bring in the rest.

#Work
1
Inflammasome Activation of Cardiac Fibroblasts Is Essential for Myocardial Ischemia/Reperfusion Injury
Circulation ·Masanori Kawaguchi, Masafumi Takahashi, Takeki Hata, Yuichiro Kashima, Fumitake Usui, Hajime Morimoto, Atsushi Izawa, Yasuko Takahashi, Junya Masumoto, Jun Koyama, Minoru Hongo, Tetsuo Noda, Jun Nakayama, Junji Sagara, Shun’ichiro Taniguchi, Uichi Ikeda
Hit paper breakdown →		2011721
2
ERM family members as molecular linkers between the cell surface glycoprotein CD44 and actin-based cytoskeletons.
The Journal of Cell Biology ·Shöichiro Tsukita, Kenichi Oishi, N Sato, Junji Sagara, Akihiko Kawai
Hit paper breakdown →		1994679
3
ASC, a Novel 22-kDa Protein, Aggregates during Apoptosis of Human Promyelocytic Leukemia HL-60 Cells
Journal of Biological Chemistry ·Junya Masumoto, Shun’ichiro Taniguchi, Koichi Ayukawa, Haritha Sarvotham, Tatsuya Kishino, Norio Niikawa, Eiko Hidaka, Tsutomu Katsuyama, Tsukasa Higuchi, Junji Sagara
1999461
4
Cryopyrin and pyrin activate caspase-1, but not NF-κB, via ASC oligomerization
Cell Death and Differentiation ·Je‐Wook Yu, Jiang Wu, Z Zhang, Pinaki Datta, Ibrahim M. Ibrahimi, S. Taniguchi, Junji Sagara, Teresa Fernandes‐Alnemri, Emad S. Alnemri
2005291
5
Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3
Nature Communications ·Seokwon Kang, Teresa Fernandes‐Alnemri, Corey Rogers, Lindsey Mayes, Ying Wang, Christopher P. Dillon, Linda Roback, William J. Kaiser, Andrew Oberst, Junji Sagara, Katherine A. Fitzgerald, Douglas R. Green, Jianke Zhang, Edward S. Mocarski, Emad S. Alnemri
2015214
6
ASC is a Bax adaptor and regulates the p53–Bax mitochondrial apoptosis pathway
Nature Cell Biology ·Takao Ohtsuka, Hoon Ryu, Yoji Andrew Minamishima, Salvador Macip, Junji Sagara, Keiichi I. Nakayama, Stuart A. Aaronson, Sam W. Lee
2004206
7
Cutting Edge: TLR Signaling Licenses IRAK1 for Rapid Activation of the NLRP3 Inflammasome
The Journal of Immunology ·Teresa Fernandes‐Alnemri, Seokwon Kang, C. Collins Anderson, Junji Sagara, Katherine A. Fitzgerald, Emad S. Alnemri
2013198
8
Apoptosis-Associated Speck-Like Protein Containing a Caspase Recruitment Domain Is a Regulator of Procaspase-1 Activation
The Journal of Immunology ·Christian Stehlik, Sug Hyung Lee, Andrea Dorfleutner, Angela Stassinopoulos, Junji Sagara, John C. Reed
2003193
9
ASC is an activating adaptor for NF-κB and caspase-8-dependent apoptosis
Biochemical and Biophysical Research Communications ·Junya Masumoto, Theresa A Dowds, Philip E. Schaner, Felicia F. Chen, Yasunori Ogura, Mu Li, Zhu Li, Tsutomu Katsuyama, Junji Sagara, Shun’ichiro Taniguchi, Deborah L. Gumucio, Gabriel Núñez, Naohiro Inohara
2003180
10
ASC is essential for LPS‐induced activation of procaspase‐1 independently of TLR‐associated signal adaptor molecules
Genes to Cells ·Masatatsu Yamamoto, Katsuyuki Yaginuma, Hiroko Tsutsui, Junji Sagara, Xin Guan, Ekihiro Seki, Koubun Yasuda, Masahiro Yamamoto, Shizuo Akira, Kenji Nakanishi, Tetsuo Noda, Shun’ichiro Taniguchi
2004158
11
Inflammasome Activation by Mitochondrial Oxidative Stress in Macrophages Leads to the Development of Angiotensin II–Induced Aortic Aneurysm
Arteriosclerosis Thrombosis and Vascular Biology ·Fumitake Usui, Koumei Shirasuna, Hiroaki Kimura, Kazuki Tatsumi, Akira Kawashima, Tadayoshi Karasawa, Koichi Yoshimura, Hiroki Aoki, Hiroko Tsutsui, Tetsuo Noda, Junji Sagara, Shun’ichiro Taniguchi, Masafumi Takahashi
2014157
12
Critical role of caspase-1 in vascular inflammation and development of atherosclerosis in Western diet-fed apolipoprotein E-deficient mice
Biochemical and Biophysical Research Communications ·Fumitake Usui, Koumei Shirasuna, Hiroaki Kimura, Kazuki Tatsumi, Akira Kawashima, Tadayoshi Karasawa, Shigeaki Hida, Junji Sagara, Shun’ichiro Taniguchi, Masafumi Takahashi
2012155
13
The PAAD/PYRIN-Family Protein ASC Is a Dual Regulator of a Conserved Step in Nuclear Factor κB Activation Pathways
The Journal of Experimental Medicine ·Christian Stehlik, Loredana Fiorentino, Andrea Dorfleutner, Jean-Marie Bruey, Eugenia M. Ariza, Junji Sagara, John C. Reed
2002138
14
Pathogenic Vibrio Activate NLRP3 Inflammasome via Cytotoxins and TLR/Nucleotide-Binding Oligomerization Domain-Mediated NF-κB Signaling
The Journal of Immunology ·Claudia Toma, Naomi Higa, Yukiko Koizumi, Noboru Nakasone, Yasunori Ogura, Andrea J. McCoy, Luigi Franchi, Satoshi Uematsu, Junji Sagara, Shun’ichiro Taniguchi, Hiroko Tsutsui, Shizuo Akira, Jürg Tschopp, Gabriel Núñez, Toshihiko Suzuki
2010114
15
NLRP3 Regulates Neutrophil Functions and Contributes to Hepatic Ischemia–Reperfusion Injury Independently of Inflammasomes
The Journal of Immunology ·Yoshiyuki Inoue, Koumei Shirasuna, Hiroaki Kimura, Fumitake Usui, Akira Kawashima, Tadayoshi Karasawa, Kenji Tago, Katsuya Dezaki, Satoshi Nishimura, Junji Sagara, Tetsuo Noda, Yoichiro Iwakura, Hiroko Tsutsui, Shun’ichiro Taniguchi, Ken Yanagisawa, Toshihiko Yada, Yoshikazu Yasuda, Masafumi Takahashi
2014107
16
Caspy, a Zebrafish Caspase, Activated by ASC Oligomerization Is Required for Pharyngeal Arch Development
Journal of Biological Chemistry ·Junya Masumoto, Weibin Zhou, Felicia F. Chen, Fengyun Su, John Y. Kuwada, Eiko Hidaka, Tsutomu Katsuyama, Junji Sagara, Shun’ichiro Taniguchi, Phuong Ngo-Hazelett, John H. Postlethwait, Gabriel Núñez, Naohiro Inohara
200393
17
Critical Role of Bone Marrow Apoptosis-Associated Speck-Like Protein, an Inflammasome Adaptor Molecule, in Neointimal Formation After Vascular Injury in Mice
Circulation ·Nobuyuki Yajima, Masafumi Takahashi, Hajime Morimoto, Yuji Shiba, Yasuko Takahashi, Junya Masumoto, Hirohiko Ise, Junji Sagara, Jun Nakayama, Shun’ichiro Taniguchi, Uichi Ikeda
200888
18
ASC/TMS1, a caspase‐1 activating adaptor, is downregulated by aberrant metylation in human melanoma
International Journal of Cancer ·Xin Guan, Junji Sagara, Taro Yokoyama, Yoko Koganehira, Misae Oguchi, Toshiaki Saida, Shun’ichiro Taniguchi
200385
19
Disease-associated mutations in CIAS1 induce cathepsin B–dependent rapid cell death of human THP-1 monocytic cells
Blood ·Akihiro Fujisawa, Naotomo Kambe, Megumu K. Saito, Ryuta Nishikomori, Hideaki Tanizaki, Nobuo Kanazawa, Souichi Adachi, Toshio Heike, Junji Sagara, Takashi Suda, Tatsutoshi Nakahata, Yoshiki Miyachi
200684
20
Expression of Apoptosis-associated Speck-like Protein Containing a Caspase Recruitment Domain, a Pyrin N-terminal Homology Domain-containing Protein, in Normal Human Tissues
Journal of Histochemistry & Cytochemistry ·Junya Masumoto, Shun’ichiro Taniguchi, Jun Nakayama, Masaaki Shiohara, Eiko Hidaka, Tsutomu Katsuyama, Sumio Murase, Junji Sagara
200182

About Junji Sagara

Junji Sagara is a scholar working on Molecular Biology, Immunology, Cell Biology, Surgery and Cancer Research, having authored 68 papers that have together received 5.8k indexed citations. Recurring topics across this work include Inflammasome and immune disorders (24 papers), Cell death mechanisms and regulation (14 papers), Immune Response and Inflammation (13 papers), interferon and immune responses (9 papers), Cell Adhesion Molecules Research (5 papers), Rabies epidemiology and control (5 papers), Cellular Mechanics and Interactions (4 papers) and Viral Infectious Diseases and Gene Expression in Insects (4 papers). The work is most often cited by research in Immunology (2.2k citations), Molecular Biology (4.3k citations), Immunology and Allergy (316 citations), Nephrology (305 citations) and Cell Biology (678 citations). Junji Sagara has collaborated with scholars based in Japan, United States and Australia. Frequent co-authors include Shun’ichiro Taniguchi, Junya Masumoto, Akihiko Kawai, Shöichiro Tsukita, Kenichi Oishi, N Sato, Masafumi Takahashi, Tetsuo Noda, Fumitake Usui and Tsutomu Katsuyama. Their work appears in journals such as The Journal of Immunology, Biochemical and Biophysical Research Communications, Journal of Biological Chemistry, The Journal of Biochemistry and The Journal of Cell Biology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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