John D. Lich

4.9k citations

31 papers · 3.7k · 1 hit paper · h-index 24

Impact in

Immunology top 1%
- interferon and immune responses
- Immune Response and Inflammation
- Immune Cell Function and Interaction
- IL-33, ST2, and ILC Pathways
Molecular Biology top 5%
- Inflammasome and immune disorders
- Cell death mechanisms and regulation
- Heme Oxygenase-1 and Carbon Monoxide

Papers in

Immunology 23
- Immune Response and Inflammation 9
- interferon and immune responses 5
- Immunotherapy and Immune Responses 4
- Phagocytosis and Immune Regulation 3
- IL-33, ST2, and ILC Pathways 2
Cancer Research 8
- NF-κB Signaling Pathways 8

Co-authors: Jenny P.‐Y. Ting (10 shared papers)Janelle C. Arthur (7 shared papers)Chris B. Moore (5 shared papers)Jenny P.‐Y. Ting (4 shared papers)Kristi L. Williams (5 shared papers)Joseph A. Duncan (4 shared papers)Zhengmao Ye (4 shared papers)Beckley K. Davis (2 shared papers)
Journals: The Journal of Immunology (6 papers)Journal of Biological Chemistry (3 papers)ACS Medicinal Chemistry Letters (2 papers)Cancer Cell (2 papers)Pharmacology Research & Perspectives (2 papers)
Partner nations: United States Germany United Kingdom

In The Last Decade

John D. Lich

30 papers receiving 3.6k citations

John D. Lich's Hit Papers

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RIP3 Induces Apoptosis Independent of Pronecrotic Kinase Activity 2014 · 535 citations

What are hit papers?

Paper score: A paper's citations measured against the top-1% bar of its own field and year: the square root of citations ÷ bar, so 1 means right at the bar and 2 means four times its citations. The bar blends the citation counts that enter the top 1% of the paper's subfields in its year (weighted 89.5%), of those subfields over all years (0.5%) and of its year across all fields (10%); a subfield and year with fewer than 400 papers takes its year's bar. Papers from 2026 are not scored yet: in an unfinished year, when a paper appeared matters more than how it is cited.

Hit paper: A paper cited at least 1.5× the top-1% bar of its field and year: a paper score of at least √1.5.

2014 Molecular Cell

Peers

Countries citing papers authored by John D. Lich

Since Specialization

Citations

This map shows the geographic impact of John D. Lich's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John D. Lich with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John D. Lich more than expected).

Fields of papers citing papers by John D. Lich

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John D. Lich. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John D. Lich. The network helps show where John D. Lich may publish in the future.

Co-authors

The 25 scholars most cited alongside John D. Lich, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with John D. Lich Line = papers co-authored together John D. Lich links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 31 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	RIP3 Induces Apoptosis Independent of Pronecrotic Kinase Activity Molecular Cell ·Pratyusha Mandal, Scott B. Berger, Sirika Pillay, Kenta Moriwaki, Chunzi Huang, Hongyan Guo, John D. Lich, Joshua N. Finger Hit paper breakdown →	2014	535
2	NLRX1 is a regulator of mitochondrial antiviral immunity Nature ·Chris B. Moore, Dan T. Bergstralh, Joseph A. Duncan, Yu L. Lei, Thomas E. Morrison, Albert G. Zimmermann, Mary Ann Accavitti-Loper, Victoria J. Madden	2008	498
3	NLRP12 Suppresses Colon Inflammation and Tumorigenesis through the Negative Regulation of Noncanonical NF-κB Signaling Immunity ·Irving C. Allen, Justin E. Wilson, Monika Schneider, John D. Lich, Reid A. Roberts, Janelle C. Arthur, Rita-Marie T. Woodford, Beckley K. Davis	2012	445
4	Autolytic Proteolysis within the Function to Find Domain (FIIND) Is Required for NLRP1 Inflammasome Activity Journal of Biological Chemistry ·Joshua N. Finger, John D. Lich, Lauren C. Dare, Michael N. Cook, Kristin K. Brown, Chaya Duraiswami, John Bertin, Peter J. Gough	2012	222
5	RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer Cancer Cell ·Wei Wang, Jill M. Marinis, Allison M. Beal, Shivraj Savadkar, Yue Wu, Mohammed Imran Khan, Pardeep S. Taunk, Nan Wu	2018	205
6	The CATERPILLER Protein Monarch-1 Is an Antagonist of Toll-like Receptor-, Tumor Necrosis Factor α-, and Mycobacterium tuberculosis-induced Pro-inflammatory Signals Journal of Biological Chemistry ·Kristi L. Williams, John D. Lich, Joseph A. Duncan, WILLIAM A. REED, Prasad Rallabhandi, Christopher E. G. Moore, Sherry L. Kurtz, Vernon M. Coffield	2005	198
7	Cutting Edge: Monarch-1 Suppresses Non-Canonical NF-κB Activation and p52-Dependent Chemokine Expression in Monocytes The Journal of Immunology ·John D. Lich, Kristi L. Williams, Chris B. Moore, Janelle C. Arthur, Beckley K. Davis, Debra J. Taxman, Jenny P.‐Y. Ting	2007	194
8	Proteomic profiling drug-induced apoptosis in non-small cell lung carcinoma: identification of RS/DJ-1 and RhoGDIalpha. PubMed ·Jeffrey P. MacKeigan, Casey M. Clements, John D. Lich, R. Marshall Pope, Yaacov Hod, Jenny P.‐Y. Ting	2003	144
9	Cytoplasmic Processing Is a Prerequisite for Presentation of an Endogenous Antigen by Major Histocompatibility Complex Class II Proteins The Journal of Experimental Medicine ·John D. Lich, John F. Elliott, Janice S. Blum	2000	129
10	Cutting Edge: NLRP12 Controls Dendritic and Myeloid Cell Migration To Affect Contact Hypersensitivity The Journal of Immunology ·Janelle C. Arthur, John D. Lich, Zhengmao Ye, Irving C. Allen, Denis Gris, Justin E. Wilson, Monika Schneider, Kelly E. Roney	2010	129
11	Discovery of Small Molecule RIP1 Kinase Inhibitors for the Treatment of Pathologies Associated with Necroptosis ACS Medicinal Chemistry Letters ·Philip A. Harris, Deepak Bandyopadhyay, Scott B. Berger, Nino Campobasso, Carol A. Capriotti, Julie A. Cox, Lauren C. Dare, Joshua N. Finger	2013	122
12	Randomized clinical study of safety, pharmacokinetics, and pharmacodynamics of RIPK 1 inhibitor GSK 2982772 in healthy volunteers Pharmacology Research & Perspectives ·Kathleen Weisel, Nicola E. Scott, Debra J. Tompson, Bartholomew J. Votta, Sujith Madhavan, Kat Povey, Allen Wolstenholme, Monica Simeoni	2017	116
13	Criteria for effective design, construction, and gene knockdown by shRNA vectors BMC Biotechnology ·Debra J Taxman, Laura R. Livingstone, Jinghua Zhang, Brian J. Conti, Heather A. Iocca, Kristi L. Williams, John D. Lich, Jenny P.‐Y. Ting	2006	104
14	ATP Binding by Monarch-1/NLRP12 Is Critical for Its Inhibitory Function Molecular and Cellular Biology ·Zhengmao Ye, John D. Lich, Chris B. Moore, Joseph A. Duncan, Kristi L. Williams, Jenny P.‐Y. Ting	2007	98
15	Identification of a RIP1 Kinase Inhibitor Clinical Candidate (GSK3145095) for the Treatment of Pancreatic Cancer ACS Medicinal Chemistry Letters ·Philip A. Harris, Jill M. Marinis, John D. Lich, Scott B. Berger, Anirudh Chirala, Julie A. Cox, Patrick M. Eidam, Joshua N. Finger	2019	72
16	Cutting Edge: ASC Mediates the Induction of Multiple Cytokines by Porphyromonas gingivalis via Caspase-1-Dependent and -Independent Pathways The Journal of Immunology ·Debra J. Taxman, Jinghua Zhang, Catherine M. Champagne, Dan T. Bergstralh, Heather A. Iocca, John D. Lich, Jenny Pan-Yun Ting	2006	70
17	Heat Shock Protein 90 Associates with Monarch-1 and Regulates Its Ability to Promote Degradation of NF-κB-Inducing Kinase The Journal of Immunology ·Janelle C. Arthur, John D. Lich, Ramy Karam Aziz, Malak Kotb, Jenny P.‐Y. Ting	2007	63
18	Characterization of NLRP12 during the In Vivo Host Immune Response to Klebsiella pneumoniae and Mycobacterium tuberculosis PLoS ONE ·Irving C. Allen, Erin McElvania, Justin E. Wilson, John D. Lich, Janelle C. Arthur, Jonathan T. Sullivan, Miriam Braunstein, Jenny P.‐Y. Ting	2013	57
19	Discovery and Lead-Optimization of 4,5-Dihydropyrazoles as Mono-Kinase Selective, Orally Bioavailable and Efficacious Inhibitors of Receptor Interacting Protein 1 (RIP1) Kinase Journal of Medicinal Chemistry ·Philip A. Harris, Nicolas Faucher, Nicolas S. George, Patrick M. Eidam, Bryan W. King, Gemma V. White, Niall A. Anderson, Deepak Bandyopadhyay	2019	57
20	Semaphorin 6D regulates the late phase of CD4 + T cell primary immune responses Proceedings of the National Academy of Sciences ·Brian P. O’Connor, So-Young Eun, Zhengmao Ye, Alla L. Zozulya, John D. Lich, Chris B. Moore, Heather A. Iocca, Kelly E. Roney	2008	57

About John D. Lich

John D. Lich is a scholar working on Immunology, Cancer Research, Molecular Biology, Oncology and Cell Biology, having authored 31 papers that have together received 3.7k indexed citations. Recurring topics across this work include Inflammasome and immune disorders (12 papers), Immune Response and Inflammation (9 papers), Cell death mechanisms and regulation (8 papers), NF-κB Signaling Pathways (8 papers), interferon and immune responses (5 papers), Immunotherapy and Immune Responses (4 papers), Phagocytosis and Immune Regulation (3 papers) and IL-33, ST2, and ILC Pathways (2 papers). The work is most often cited by research in Immunology (2.0k citations), Molecular Biology (2.5k citations), Cancer Research (315 citations), Biological Psychiatry (39 citations) and Oncology (404 citations). John D. Lich has collaborated with scholars based in United States, Germany and United Kingdom. Frequent co-authors include Jenny P.‐Y. Ting, Janelle C. Arthur, Chris B. Moore, Jenny P.‐Y. Ting, Kristi L. Williams, Joseph A. Duncan, Zhengmao Ye, Beckley K. Davis, Irving C. Allen and Mary Ann Accavitti-Loper. Their work appears in journals such as The Journal of Immunology, Journal of Biological Chemistry, ACS Medicinal Chemistry Letters, Cancer Cell and Pharmacology Research & Perspectives.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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John D. Lich

John D. Lich's Hit Papers

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