John C. Sih

850 citations

30 papers · 610 · h-index 13

Impact in

Organic Chemistry top 5%
- Asymmetric Synthesis and Catalysis
- Synthetic Organic Chemistry Methods
- Catalytic C–H Functionalization Methods
- Chemical Synthesis and Reactions
- Oxidative Organic Chemistry Reactions
- Synthesis and Catalytic Reactions
Toxicology top 10%

Papers in

Organic Chemistry 18
- Organic Chemistry Cycloaddition Reactions 7
- Chemical Reaction Mechanisms 3
- Chemical Synthesis and Reactions 3
Molecular Biology 15
- Enzyme Catalysis and Immobilization 3
- Steroid Chemistry and Biochemistry 3
- Microbial Metabolic Engineering and Bioproduction 3

Co-authors: Josef Fried (3 shared papers)Wha Bin Im (2 shared papers)David P. Blakeman (2 shared papers)David R. Graber (9 shared papers)John P. McGrath (1 shared paper)Kevin E. Henegar (2 shared papers)James M. Bobbitt (1 shared paper)C. H. LIN (2 shared papers)
Journals: The Journal of Organic Chemistry (11 papers)Prostaglandins (4 papers)Journal of Medicinal Chemistry (3 papers)Journal of the American Chemical Society (2 papers)Tetrahedron (1 paper)
Partner nations: United States

In The Last Decade

John C. Sih

28 papers receiving 562 citations

Peers

Countries citing papers authored by John C. Sih

Since Specialization

Citations

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Fields of papers citing papers by John C. Sih

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John C. Sih. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John C. Sih. The network helps show where John C. Sih may publish in the future.

Co-authors

The 25 scholars most cited alongside John C. Sih, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with John C. Sih Line = papers co-authored together John C. Sih links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 30 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Omeprazole, a specific inhibitor of gastric (H+-K+)-ATPase, is a H+-activated oxidizing agent of sulfhydryl groups. Journal of Biological Chemistry ·Wha Bin Im, John C. Sih, David P. Blakeman, John P. McGrath	1985	89
2	(S)-(−)-4-[4-[2-(Isochroman-1-yl)ethyl]piperazin-1-yl]benzenesulfonamide, a Selective Dopamine D₄ Antagonist Journal of Medicinal Chemistry ·Ruth E. TenBrink, Carol L. Bergh, J. Neil Duncan, Douglas W. Harris, Rita M. Huff, Robert A. Lahti, Charles Lawson, Barry S. Lutzke, Iain Martin, Susan A. Rees, Siusaidh K. Schlachter, John C. Sih, Martin Smith	1996	85
3	Practical Asymmetric Synthesis of (S)-4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine- 3,6,10(4H)-trione, a Key Intermediate for the Synthesis of Irinotecan and Other Camptothecin Analogs The Journal of Organic Chemistry ·Kevin E. Henegar, Scott W. Ashford, Ted A. Baughman, John C. Sih, Rui-Lin Gu	1997	71
4	Synthesis and Biological Activity of Analogues of the Antidiabetic/Antiobesity Agent 3-Guanidinopropionic Acid: Discovery of a Novel Aminoguanidinoacetic Acid Antidiabetic Agent Journal of Medicinal Chemistry ·Scott D. Larsen, Mark A. Connell, Michele M. Cudahy, Bruce R. Evans, Paul D. May, Martin D. Meglasson, Theresa J. O’Sullivan, Heinrich J. Schostarez, John C. Sih, Frits C. Stevens, Steven P. Tanis, Christopher M. Tegley, John A. Tucker, Valerie Vaillancourt, Thomas J. Vidmar, William Watt, Jen H. Yu	2001	54
5	Total synthesis of prostaglandins. Control of regiospecificity in the alane-epoxide reaction and selective catalytic oxidation of alkynylation products Tetrahedron Letters ·Josef Fried, John C. Sih	1973	50
6	Stereospecific total synthesis of the natural and racemic prostaglandins of the E and F series Journal of the American Chemical Society ·Josef Fried, C. H. Lin, John C. Sih, P. Dalven, Gary F. Cooper	1972	42
7	Regiospecific epoxide opening with acetylenic alanes. Improved total synthesis of E and F prostaglandins Journal of the American Chemical Society ·Josef Fried, John C. Sih, C. H. LIN, P. Dalven	1972	32
8	Synthesis of isoquinolines. VII. 4-Hydroxy-1,2,3,4-tetrahydroisoquinolines The Journal of Organic Chemistry ·James M. Bobbitt, John C. Sih	1968	29
9	Reaction of 2-(alkylsulfinyl)-, 2-(arylsulfinyl)-, and 2-(aralkylsulfinyl)benzimidazoles with thiols: a convenient synthesis of unsymmetrical disulfides The Journal of Organic Chemistry ·David R. Graber, Raymond A. Morge, John C. Sih	1987	21
10	Studies on (H+-K+)-ATPase inhibitors of gastric acid secretion. Prodrugs of 2-[(2-pyridinylmethyl)sulfinyl]benzimidazole proton-pump inhibitors Journal of Medicinal Chemistry ·John C. Sih, Wha Bin Im, André Robert, David R. Graber, David P. Blakeman	1991	17
11	The synthesis of 2,3-dinorprostacyclin metabolites—a new approach to spirolactone hemiacetals Tetrahedron ·Gordon L. Bundy, C. H. LIN, John C. Sih	1981	15
12	Seven-membered heterocycles. VII. Synthesis and properties of 1-benzothiepin and its chlorinated derivatives The Journal of Organic Chemistry ·Vincent J. Traynelis, Yoichiro Yoshikawa, John C. Sih, Larkey J. Miller, Joel R. Livingston	1973	15
13	Synthesis of the four isomers of 5-hydroxy-PGI1 Prostaglandins ·John C. Sih, Roy A. Johnson, Eldon G. Nidy, David R. Graber	1978	12
14	ChemInform Abstract: SEVEN‐MEMBERED HETEROCYCLES PART 7, THE SYNTHESIS AND PROPERTIES OF 1‐BENZOTHIEPIN AND ITS CHLORINATED DERIVATIVES Chemischer Informationsdienst ·Vincent J. Traynelis, Yozaburo Yoshikawa, John C. Sih, L. J. MILLER, Joel R. Livingston	1974	11
15	Differences in reactivity and enantioselectivity in lipase reactions with carboxylic esters and alcohols bearing the same stereogenic center Tetrahedron Asymmetry ·John C. Sih, Rui Lin Gu	1995	10
16	Synthesis of six-membered-ring analogs of 6.alpha.-carba-PGI2 The Journal of Organic Chemistry ·John C. Sih	1982	9
17	Synthesis of (5E)- and (5Z)-11-deoxy-6,11.alpha.-epoxy-.DELTA.5-prostaglandin F1.alpha. sodium salts: 6,11.alpha.-enol ether isomers of prostacyclin The Journal of Organic Chemistry ·John C. Sih, David R. Graber	1982	8
18	Seven-membered heterocycles. VI. 4-Alkylidene-1-benzothiepin-5(2H)-ones and the reaction of halogenated 3,4-dihydro-1-benzothiepin-5(2H)-ones with base The Journal of Organic Chemistry ·Vincent J. Traynelis, John C. Sih, Dan M. Borgnaes	1973	8
19	Synthesis of (6R)- and (6S)-6(9)-oxy-11,15-dihydroxyprosta-7,13-dienoic acids [(6R)- and (6S)-.DELTA.7-PGI1]: nonidentity with the proposed arachidonic acid metabolite The Journal of Organic Chemistry ·John C. Sih, David R. Graber	1978	5
20	Synthesis of carbon‐14 labeled disuprazole Journal of Labelled Compounds and Radiopharmaceuticals ·Wayne T. Stolle, John C. Sih, Richard S. P. Hsi	1988	4

About John C. Sih

John C. Sih is a scholar working on Organic Chemistry, Molecular Biology, Pharmacology, Oncology and Cancer Research, having authored 30 papers that have together received 610 indexed citations. Recurring topics across this work include Organic Chemistry Cycloaddition Reactions (7 papers), Inflammatory mediators and NSAID effects (5 papers), Enzyme Catalysis and Immobilization (3 papers), Chemical Reaction Mechanisms (3 papers), Steroid Chemistry and Biochemistry (3 papers), Chemical Synthesis and Reactions (3 papers), Microbial Metabolic Engineering and Bioproduction (3 papers) and Sesquiterpenes and Asteraceae Studies (2 papers). The work is most often cited by research in Organic Chemistry (380 citations), Toxicology (20 citations), Biochemistry (41 citations), Pharmacology (71 citations) and Gastroenterology (19 citations). John C. Sih has collaborated with scholars based in United States. Frequent co-authors include Josef Fried, Wha Bin Im, David P. Blakeman, David R. Graber, John P. McGrath, Kevin E. Henegar, James M. Bobbitt, C. H. LIN, Vincent J. Traynelis and Gary F. Cooper. Their work appears in journals such as The Journal of Organic Chemistry, Prostaglandins, Journal of Medicinal Chemistry, Journal of the American Chemical Society and Tetrahedron.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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