I.G. Sipes

13.4k citations

235 papers · 7.8k · h-index 52

Impact in

Pharmacology top 0.05%
- Pharmacogenetics and Drug Metabolism
- Drug-Induced Hepatotoxicity and Protection
Health, Toxicology and Mutagenesis top 0.2%
- Effects and risks of endocrine disrupting chemicals
- Toxic Organic Pollutants Impact

Papers in

Pharmacology 73
- Pharmacogenetics and Drug Metabolism 60
- Drug-Induced Hepatotoxicity and Protection 28
Molecular Biology 54

Co-authors: Patricia B. Hoyer (35 shared papers)A. Jay Gandolfi (32 shared papers)Robert K. Kuester (18 shared papers)Gopal Krishna (3 shared papers)Klaus Brendel (18 shared papers)David R. Bickers (17 shared papers)Helmut Greim (17 shared papers)Peter Calow (17 shared papers)
Journals: Toxicology and Applied Pharmacology (42 papers)Drug Metabolism and Disposition (21 papers)Food and Chemical Toxicology (21 papers)Biochemical Pharmacology (11 papers)Toxicology (9 papers)
Partner nations: United States Germany Switzerland

In The Last Decade

I.G. Sipes

232 papers receiving 7.4k citations

Peers

Replace Tamie Nakajima with:

Tamie Nakajima Japan

Hansruedi Glatt Germany

S.D. Gangolli United Kingdom

Rolf Schulte‐Hermann Austria

Eleanor G. Rogan United States

James E. Klaunig United States

Gary M. Williams United States

Masao Hirose Japan

T.M. Penning United States

Franz Oesch Germany

I.G. Sipes relative to Tamie Nakajima Japan Tamie Nakajima's profile →

Citations per field

00.5×2×3.2×

Tamie Nakajima · 1×

×2.1 2k/827

PHARM

×0.8 2k/2k

HTM

×1.0 1k/1k

CR

×1.3 529/392

BIOCH

×3.2 438/139

RM

Citations per year

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Countries citing papers authored by I.G. Sipes

Since Specialization

Citations

This map shows the geographic impact of I.G. Sipes's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by I.G. Sipes with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites I.G. Sipes more than expected).

Fields of papers citing papers by I.G. Sipes

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by I.G. Sipes. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by I.G. Sipes. The network helps show where I.G. Sipes may publish in the future.

Co-authors

The 25 scholars most cited alongside I.G. Sipes, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with I.G. Sipes Line = papers co-authored together I.G. Sipes links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 235 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Safety assessment of allylalkoxybenzene derivatives used as flavouring substances — methyl eugenol and estragole Food and Chemical Toxicology ·Robert L. Smith, Timothy B. Adams, John Doull, V.J. Feron, Jay I. Goodman, Lawrence J. Marnett, Philip S. Portoghese, William J. Waddell, Bernard M. Wagner, Adrianne E. Rogers, John Caldwell, I.G. Sipes	2002	202
2	Bioactivation of carbon tetrachloride, chloroform and bromotrichloromethane: Role of cytochrome P-450 Life Sciences ·I.G. Sipes, Gopal Krishna, James R. Gillette	1977	171
3	Chloroform toxicity in mice: Correlation of renal and hepatic necrosis with covalent binding of metabolites to tissue macromolecules Experimental and Molecular Pathology ·Kenneth F. Ilett, Watson D. Reid, I.G. Sipes, Gopal Krishna	1973	151
4	Ovotoxicity in Female Fischer Rats and B6 Mice Induced by Low-Dose Exposure to Three Polycyclic Aromatic Hydrocarbons: Comparison through Calculation of an Ovotoxic Index Toxicology and Applied Pharmacology ·Sherri Borman, Patricia J. Christian, I.G. Sipes, Patricia B. Hoyer	2000	134
5	Pharmacokinetics of acrylamide in Fisher-334 rats Toxicology and Applied Pharmacology ·M.J. Miller, D.E. Carter, I.G. Sipes	1982	134
6	Long-term effects of ovarian follicular depletion in rats by 4-vinylcyclohexene diepoxide Reproductive Toxicology ·Loretta P. Mayer, Nicole A Pearsall, Patricia J. Christian, Patrick J. Devine, Claire M. Payne, Margaret K. McCuskey, Samuel L. Marion, I.G. Sipes, Patricia B. Hoyer	2002	128
7	Involvement of Apoptosis in 4-Vinylcyclohexene Diepoxide- Induced Ovotoxicity in Rats Toxicology and Applied Pharmacology ·Lisa Springer, Mary E. McAsey, Jodi A. Flaws, J. L. Tilly, I.G. Sipes, Patricia B. Hoyer	1996	123
8	A toxicologic and dermatologic assessment of cyclic and non-cyclic terpene alcohols when used as fragrance ingredients Food and Chemical Toxicology ·D. Belsito, David R. Bickers, M. Bruze, Peter Calow, Helmut Greim, Jon M. Hanifin, Adrianne E. Rogers, J.‐H. Saurat, I.G. Sipes, Hachiro Tagami	2008	122
9	Destruction of preantral follicles in adult rats by 4-vinyl-1-cyclohexene diepoxide Reproductive Toxicology ·Jodi A. Flaws, Julie K. Doerr, I.G. Sipes, Patricia B. Hoyer	1994	112
10	An Updated Weight of the Evidence Evaluation of Reproductive and Developmental Effects of Low Doses of Bisphenol A Critical Reviews in Toxicology ·Julie E. Goodman, Ernest E. McConnell, I.G. Sipes, Raphael J. Witorsch, Tracey M. Slayton, Carrie J. Yu, Ari S. Lewis, Lorenz R. Rhomberg	2006	112
11	A toxicologic and dermatologic assessment of cinnamyl alcohol, cinnamaldehyde and cinnamic acid when used as fragrance ingredients Food and Chemical Toxicology ·David R. Bickers, Peter Calow, Helmut Greim, Jon M. Hanifin, Adrianne E. Rogers, J.‐H. Saurat, I.G. Sipes, Robert L. Smith, Hachiro Tagami	2005	111
12	Metabolism of Bisphenol A in Primary Cultured Hepatocytes from Mice, Rats, and Humans Drug Metabolism and Disposition ·J. J. Pritchett, Robert K. Kuester, I.G. Sipes	2002	109
13	The safety assessment of fragrance materials Regulatory Toxicology and Pharmacology ·David R. Bickers, Peter Calow, Helmut Greim, Jon M. Hanifin, Adrianne E. Rogers, J.‐H. Saurat, I.G. Sipes, Robert L. Smith, Hachiro Tagami	2003	102
14	Assessment of Follicle Destruction in Chemical-Induced Ovarian Toxicity The Annual Review of Pharmacology and Toxicology ·Patricia B. Hoyer, I.G. Sipes	1996	102
15	A toxicologic and dermatologic assessment of linalool and related esters when used as fragrance ingredients Food and Chemical Toxicology ·David R. Bickers, Peter Calow, Helmut Greim, Jon M. Hanifin, Adrianne E. Rogers, J.‐H. Saurat, I.G. Sipes, Robert L. Smith, Hachiro Tagami	2003	99
16	Enhanced hepatotoxicity of carbon tetrachloride, thioacetamide, and dimethylnitrosamine by pretreatment of rats with ethanol and some comparisons with potentiation by isopropanol Toxicology and Applied Pharmacology ·Harriet M. Maling, Barry R. Stripp, I.G. Sipes, Benjamin Highman, W. Saul, M.A. Williams	1975	99
17	Hypothyroxinemia and hypothermia in rats in response to 2,3,7,8-tetrachlorodibenzo-p-dioxin administration Toxicology and Applied Pharmacology ·Carl L. Potter, I.G. Sipes, Diane Haddock Russell	1983	97
18	Vitamin A Potentiation of Carbon Tetrachloride Hepatotoxicity: Role of Liver Macrophages and Active Oxygen Species Toxicology and Applied Pharmacology ·Alaa E. El‐Sisi, David L. Earnest, I.G. Sipes	1993	91
19	The role of epoxidation in 4-vinylcyclohexene-induced ovarian toxicity Toxicology and Applied Pharmacology ·Bill J. Smith, Donald R. Mattison, I.G. Sipes	1990	91
20	In vitro solubility and in vivo toxicity of gallium arsenide Toxicology and Applied Pharmacology ·D.R. Webb, I.G. Sipes, D.E. Carter	1984	88

About I.G. Sipes

I.G. Sipes is a scholar working on Pharmacology, Molecular Biology, Cancer Research, Health, Toxicology and Mutagenesis and Public Health, Environmental and Occupational Health, having authored 235 papers that have together received 7.8k indexed citations. Recurring topics across this work include Pharmacogenetics and Drug Metabolism (60 papers), Carcinogens and Genotoxicity Assessment (49 papers), Effects and risks of endocrine disrupting chemicals (36 papers), Reproductive Biology and Fertility (29 papers), Drug-Induced Hepatotoxicity and Protection (28 papers), Animal testing and alternatives (18 papers), Contact Dermatitis and Allergies (17 papers) and Drug Transport and Resistance Mechanisms (16 papers). The work is most often cited by research in Pharmacology (1.7k citations), Health, Toxicology and Mutagenesis (2.0k citations), Cancer Research (1.4k citations), Biochemistry (529 citations) and Reproductive Medicine (438 citations). I.G. Sipes has collaborated with scholars based in United States, Germany and Switzerland. Frequent co-authors include Patricia B. Hoyer, A. Jay Gandolfi, Robert K. Kuester, Gopal Krishna, Klaus Brendel, David R. Bickers, Helmut Greim, Peter Calow, J.‐H. Saurat and Adrianne E. Rogers. Their work appears in journals such as Toxicology and Applied Pharmacology, Drug Metabolism and Disposition, Food and Chemical Toxicology, Biochemical Pharmacology and Toxicology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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