Ernst U. Frevert

2.2k citations

24 papers · 1.7k · 1 hit paper · h-index 16

Impact in

Endocrinology, Diabetes and Metabolism top 2%
- Diabetes Treatment and Management
Molecular Biology top 10%
- Metabolism, Diabetes, and Cancer
- Protein Tyrosine Phosphatases
- Protein Kinase Regulation and GTPase Signaling
- PI3K/AKT/mTOR signaling in cancer

Papers in

Molecular Biology 12
- Metabolism, Diabetes, and Cancer 9
- Protein Kinase Regulation and GTPase Signaling 2
Surgery 7
- Pancreatic function and diabetes 6

Co-authors: Barbara B. Kahn (9 shared papers)William J. Chiou (4 shared papers)Barbara L. Cool (3 shared papers)Lemma Kifle (3 shared papers)Philip R. Kym (2 shared papers)Gang Zhao (2 shared papers)Heidi S. Camp (3 shared papers)Ning Cao (2 shared papers)
Journals: Bioorganic & Medicinal Chemistry Letters (5 papers)European Journal of Endocrinology (3 papers)Molecular and Cellular Biology (2 papers)Journal of Biological Chemistry (2 papers)Assay and Drug Development Technologies (1 paper)
Partner nations: United States Germany United Kingdom

In The Last Decade

Ernst U. Frevert

24 papers receiving 1.7k citations

Ernst U. Frevert's Hit Papers

align trajectories log scale

Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome 2006 · 736 citations

Peers

Countries citing papers authored by Ernst U. Frevert

Since Specialization

Citations

This map shows the geographic impact of Ernst U. Frevert's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ernst U. Frevert with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ernst U. Frevert more than expected).

Fields of papers citing papers by Ernst U. Frevert

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ernst U. Frevert. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ernst U. Frevert. The network helps show where Ernst U. Frevert may publish in the future.

Co-authors

The 25 scholars most cited alongside Ernst U. Frevert, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Ernst U. Frevert Line = papers co-authored together Ernst U. Frevert links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Showing the 20 most-cited of 24 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome Cell Metabolism ·Barbara L. Cool, Bradley A. Zinker, William J. Chiou, Lemma Kifle, Ning Cao, Matthew Perham, Robert Dickinson, Andrew Adler, Gerard D. Gagné, Rajesh Iyengar, Gang Zhao, Kennan Marsh, Philip R. Kym, Paul Jung, Heidi S. Camp, Ernst U. Frevert Hit paper breakdown →	2006	736
2	Regulation of Early Events in Integrin Signaling by Protein Tyrosine Phosphatase SHP-2 Molecular and Cellular Biology ·Eok‐Soo Oh, Haihua Gu, Tracy M. Saxton, John F. Timms, Sharon F. Hausdorff, Ernst U. Frevert, Barbara B. Kahn, Tony Pawson, Benjamin G. Neel, Sheila Μ. Thomas	1999	190
3	Differential Effects of Constitutively Active Phosphatidylinositol 3-Kinase on Glucose Transport, Glycogen Synthase Activity, and DNA Synthesis in 3T3-L1 Adipocytes Molecular and Cellular Biology ·Ernst U. Frevert, Barbara B. Kahn	1997	155
4	Overexpression of Protein-tyrosine Phosphatase-1B in Adipocytes Inhibits Insulin-stimulated Phosphoinositide 3-Kinase Activity without Altering Glucose Transport or Akt/Protein Kinase B Activation Journal of Biological Chemistry ·Carol L. Venable, Ernst U. Frevert, Young‐Bum Kim, Britta Fischer, Shubhangi Kamatkar, Benjamin G. Neel, Barbara B. Kahn	2000	96
5	Evidence Against a Direct Effect of Leptin on Glucose Transport in Skeletal Muscle and Adipocytes Diabetes ·Juleen R. Zierath, Ernst U. Frevert, Jeffrey W. Ryder, Per‐Olof Berggren, Barbara B. Kahn	1998	93
6	Influence of Renal or Hepatic Impairment on the Pharmacokinetics of Saxagliptin Clinical Pharmacokinetics ·David W. Boulton, Li Li, Ernst U. Frevert, Angela Tang, Lorna Castaneda, Nimish N. Vachharajani, David M. Kornhauser, Chirag G. Patel	2011	85
7	Two-way pharmacokinetic interaction studies between saxagliptin and cytochrome P450 substrates or inhibitors: simvastatin, diltiazem extended-release, and ketoconazole Clinical Pharmacology Advances and Applications ·Chirag Patel, Li Li, Suzette Girgis, David M. Kornhauser, Ernst U. Frevert, David W. Boulton	2011	39
8	Protein kinase C isoforms ɛ, η, δ and ζ in murine adipocytes: expression, subcellular localization and tissue-specific regulation in insulin-resistant states Biochemical Journal ·Ernst U. Frevert, Barbara B. Kahn	1996	38
9	Targeting of Constitutively Active Phosphoinositide 3-Kinase to GLUT4-containing Vesicles in 3T3-L1 Adipocytes Journal of Biological Chemistry ·Ernst U. Frevert, Christian Bjørbæk, Carol L. Venable, Susanna R. Keller, Barbara B. Kahn	1998	36
10	Discovery and SAR development of thienopyridones: A class of small molecule AMPK activators Bioorganic & Medicinal Chemistry Letters ·Gang Zhao, Rajesh R. Iyengar, Andrew S. Judd, Barbara L. Cool, William J. Chiou, Lemma Kifle, Ernst U. Frevert, Hing L. Sham, Philip R. Kym	2007	31
11	Adamantane 11-β-HSD-1 inhibitors: Application of an isocyanide multicomponent reaction Bioorganic & Medicinal Chemistry Letters ·Bryan K. Sorensen, Jeff Rohde, Jiahong Wang, Steven Fung, Katina Monzon, William J. Chiou, Liping Pan, X.Q. Deng, DeAnne Stolarik, Ernst U. Frevert, Peer B. Jacobson, J. T. Link	2006	30
12	Adenovirus-Mediated Gene Transfer of Dominant Negative Ras^asn17in 3T3L1 Adipocytes Does Not Alter Insulin-Stimulated PI3-Kinase Activity or Glucose Transport Molecular Endocrinology ·Luigi Gnudi, Ernst U. Frevert, Karen L. Houseknecht, Péter Erhardt, Barbara B. Kahn	1997	27
13	Microarrayed Compound Screening (μARCS) to Identify Activators and Inhibitors of AMP-Activated Protein Kinase SLAS DISCOVERY ·Steven N. Anderson, Barbara L. Cool, Lemma Kifle, William J. Chiou, David A. Egan, Leo W. Barrett, Paul L. Richardson, Ernst U. Frevert, Usha Warrior, James L. Kofron, David J. Burns	2004	27
14	Discovery of potent and selective inhibitors of 11β-HSD1 for the treatment of metabolic syndrome Bioorganic & Medicinal Chemistry Letters ·Steven J. Richards, Bryan K. Sorensen, Hwan-Soo Jae, Marty Winn, Yixian Chen, Jiahong Wang, Steven Fung, Katina Monzon, Ernst U. Frevert, Peer B. Jacobson, Hing L. Sham, J. T. Link	2006	17
15	The synthesis and structure–activity relationship studies of selective acetyl-CoA carboxylase inhibitors containing 4-(thiazol-5-yl)but-3-yn-2-amino motif: Polar region modifications Bioorganic & Medicinal Chemistry Letters ·Xiangdong Xu, Moshe Weitzberg, Robert F. Keyes, Qun Li, Rongqi Wang, Xiaojun Wang, Xiaolin Zhang, Ernst U. Frevert, Heidi S. Camp, Bruce A. Beutel, Hing L. Sham, Yu Gu	2006	16
16	Bioequivalence of Saxagliptin/Metformin Immediate Release (IR) Fixed-Dose Combination Tablets and Single-Component Saxagliptin and Metformin IR Tablets in Healthy Adult Subjects Clinical Drug Investigation ·Vijay Upreti, Chi-Fung Keung, David W. Boulton, Ming Chang, Li Li, Angela Tang, Bonnie C. Hsiang, Donette Quamina‐Edghill, Ernst U. Frevert, Frank LaCreta	2013	15
17	Studies on the subcellular mechanisms mediating the negative estradiol effect on GnRH-induced LH-release by rat pituitary cells in culture European Journal of Endocrinology ·Günter Emons, Ernst U. Frevert, Olaf Ortmann, U. FINGSCHEIDT, R. Sturm, Ludwig Kiesel, R. Knüppen	1989	13
18	Structure–activity relationships for a novel series of thiazolyl phenyl ether derivatives exhibiting potent and selective acetyl-CoA carboxylase 2 inhibitory activity Bioorganic & Medicinal Chemistry Letters ·Richard F. Clark, Tianyuan Zhang, Zhili Xin, Gang Liu, Ying Wang, Terkel Hansen, Xiaojun Wang, Rongqi Wang, Xiaolin Zhang, Ernst U. Frevert, Heidi S. Camp, Bruce A. Beutel, Hing L. Sham, Yu Gu	2006	13
19	Markers of bone metabolism during short-term administration of thyroxine in healthy volunteers European Journal of Endocrinology ·Ernst U. Frevert, A Biester, Manfred J. Müller, H. Schmidt‐Gayk, A. von zur Mühlen, Georg Brabant	1994	11
20	Adenovirus-mediated expression of a naturally occurring Asp905Tyr variant of the glycogen-associated regulatory subunit of protein phosphatase-1 in L6 myotubes Diabetologia ·Søren K. Rasmussen, Lars Hansen, Ernst U. Frevert, Philip Cohen, Barbara B. Kahn, Oluf Pedersen	2000	9

About Ernst U. Frevert

Ernst U. Frevert is a scholar working on Molecular Biology, Surgery, Endocrinology, Diabetes and Metabolism, Physiology and Epidemiology, having authored 24 papers that have together received 1.7k indexed citations. Recurring topics across this work include Metabolism, Diabetes, and Cancer (9 papers), Pancreatic function and diabetes (6 papers), Adipose Tissue and Metabolism (4 papers), Diabetes Treatment and Management (3 papers), Adipokines, Inflammation, and Metabolic Diseases (3 papers), Protein Kinase Regulation and GTPase Signaling (2 papers), Hormonal Regulation and Hypertension (2 papers) and Hypothalamic control of reproductive hormones (2 papers). The work is most often cited by research in Endocrinology, Diabetes and Metabolism (372 citations), Molecular Biology (1.1k citations), Geriatrics and Gerontology (45 citations), Physiology (63 citations) and Endocrine and Autonomic Systems (84 citations). Ernst U. Frevert has collaborated with scholars based in United States, Germany and United Kingdom. Frequent co-authors include Barbara B. Kahn, William J. Chiou, Barbara L. Cool, Lemma Kifle, Philip R. Kym, Gang Zhao, Heidi S. Camp, Ning Cao, Andrew Adler and Bradley A. Zinker. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, European Journal of Endocrinology, Molecular and Cellular Biology, Journal of Biological Chemistry and Assay and Drug Development Technologies.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

Ernst U. Frevert

Impact in

Papers in i

In The Last Decade

Ernst U. Frevert

Ernst U. Frevert's Hit Papers

Peers

Countries citing papers authored by Ernst U. Frevert

Fields of papers citing papers by Ernst U. Frevert

All Works

About Ernst U. Frevert

Explore authors with similar magnitude of impact

Papers in