Daniel S. Pilch

4.6k citations

86 papers · 4.2k · h-index 41

Impact in

Molecular Medicine top 1%
- Antibiotic Resistance in Bacteria
Toxicology top 1%

Papers in

Molecular Biology 72
- DNA and Nucleic Acid Chemistry 37
- RNA and protein synthesis mechanisms 23
- Cancer therapeutics and mechanisms 21
- Advanced biosensing and bioanalysis techniques 20
- RNA Interference and Gene Delivery 12
Molecular Medicine 20
- Antibiotic Resistance in Bacteria 20

Co-authors: Malvika Kaul (29 shared papers)Edmond J. LaVoie (45 shared papers)Christopher M. Barbieri (17 shared papers)Kenneth J. Breslauer (14 shared papers)Richard H. Shafer (4 shared papers)Ajit K Parhi (21 shared papers)John E. Kerrigan (8 shared papers)Leroy F. Liu (18 shared papers)
Journals: Biochemistry (12 papers)Bioorganic & Medicinal Chemistry Letters (10 papers)Journal of Molecular Biology (7 papers)Journal of the American Chemical Society (6 papers)Antimicrobial Agents and Chemotherapy (5 papers)
Partner nations: United States France United Kingdom

In The Last Decade

Daniel S. Pilch

86 papers receiving 4.0k citations

Peers

Countries citing papers authored by Daniel S. Pilch

Since Specialization

Citations

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Fields of papers citing papers by Daniel S. Pilch

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Daniel S. Pilch. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Daniel S. Pilch. The network helps show where Daniel S. Pilch may publish in the future.

Co-authors

The 25 scholars most cited alongside Daniel S. Pilch, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Daniel S. Pilch Line = papers co-authored together Daniel S. Pilch links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

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#	Work
1	Influence of cisplatin intrastrand crosslinking on the conformation, thermal stability, and energetics of a 20-mer DNA duplex. Proceedings of the National Academy of Sciences ·(unknown), Daniel S. Pilch, Stephen J. Lippard, Earl Redding, Stephen U. Dunham, Kenneth J. Breslauer	1996	175
2	Development of Novel Aminoglycoside (NB54) with Reduced Toxicity and Enhanced Suppression of Disease-Causing Premature Stop Mutations Journal of Medicinal Chemistry ·Igor Nudelman, Annie Rebibo-Sabbah, Marina Cherniavsky, Valery Belakhov, Mariana Hainrichson, Fuquan Chen, Jochen Schacht, Daniel S. Pilch, Tamar Ben‐Yosef, Timor Baasov	2009	162
3	Structure, stability, and thermodynamics of a short intermolecular purine-purine-pyrimidine triple helix Biochemistry ·Daniel S. Pilch, Corey Levenson, Richard H. Shafer	1991	157
4	Antibacterial activity of quinoxalines, quinazolines, and 1,5-naphthyridines Bioorganic & Medicinal Chemistry Letters ·Ajit K Parhi, Yong‐Zheng Zhang, Kurt W. Saionz, Padmanava Pradhan, Malvika Kaul, Kalkal Trivedi, Daniel S. Pilch, Edmond J. LaVoie	2013	149
5	Structural analysis of the (dA)10.2(dT)10 triple helix. Proceedings of the National Academy of Sciences ·Daniel S. Pilch, C. Levenson, Richard H. Shafer	1990	138
6	Thermodynamics of Aminoglycoside−rRNA Recognition: The Binding of Neomycin-Class Aminoglycosides to the A Site of 16S rRNA Biochemistry ·Malvika Kaul, Daniel S. Pilch	2002	129
7	Nucleic Acid Hybridization: Triplex Stability and Energetics Annual Review of Biophysics and Biomolecular Structure ·Georg Plum, Daniel S. Pilch, Scott F. Singleton, Kenneth J. Breslauer	1995	119
8	Fluorescence-Based Approach for Detecting and Characterizing Antibiotic-Induced Conformational Changes in Ribosomal RNA: Comparing Aminoglycoside Binding to Prokaryotic and Eukaryotic Ribosomal RNA Sequences Journal of the American Chemical Society ·Malvika Kaul, Christopher M. Barbieri, Daniel S. Pilch	2004	110
9	Coupling of Drug Protonation to the Specific Binding of Aminoglycosides to the A Site of 16S rRNA: Elucidation of the Number of Drug Amino Groups Involved and their Identities Journal of Molecular Biology ·Malvika Kaul, Christopher M. Barbieri, John E. Kerrigan, Daniel S. Pilch	2003	109
10	Berenil [1,3-Bis(4'-amidinophenyl)triazene] Binding to DNA Duplexes and to a RNA Duplex: Evidence for Both Intercalative and Minor Groove Binding Properties Biochemistry ·Daniel S. Pilch, Michael A. Kirolos, Xiaoyan Liu, Georg Plum, Kenneth J. Breslauer	1995	107
11	TXA709, an FtsZ-Targeting Benzamide Prodrug with Improved Pharmacokinetics and Enhanced In Vivo Efficacy against Methicillin-Resistant Staphylococcus aureus Antimicrobial Agents and Chemotherapy ·Malvika Kaul, Lilly Mark, Yongzheng Zhang, Ajit K Parhi, Yi Lisa Lyu, Joan Pawlak, Stephanie N. Saravolatz, Louis D. Saravolatz, Melvin P. Weinstein, Edmond J. LaVoie, Daniel S. Pilch	2015	106
12	Minor Groove-Directed and Intercalative Ligand−DNA Interactions in the Poisoning of Human DNA Topoisomerase I by Protoberberine Analogs Biochemistry ·Daniel S. Pilch, Chiang Yu, Darshan Makhey, Edmond J. LaVoie, A. R. Srinivasan, Wilma K. Olson, Ronald R. Sauers, Kenneth J. Breslauer, Nicholas E. Geacintov, Leroy F. Liu	1997	103
13	Thermodynamics of triple helix formation: spectrophotometric studies on the d(A)₁₀·2d(T)₁₀and d(C⁺₃T₃C⁺₃)·d(G₃A₄G₃)·d(C₃T₄C₃) triple helices Nucleic Acids Research ·Daniel S. Pilch, Roland Brousseau, Richard H. Shafer	1990	102
14	Binding of a hairpin polyamide in the minor groove of DNA: sequence-specific enthalpic discrimination. Proceedings of the National Academy of Sciences ·Daniel S. Pilch, (unknown), Craig A. Gelfand, Scott M. Law, Kenneth J. Breslauer, E.E. Baird, Peter B. Dervan	1996	94
15	Aminoglycoside-Induced Reduction in Nucleotide Mobility at the Ribosomal RNA A-Site as a Potentially Key Determinant of Antibacterial Activity Journal of the American Chemical Society ·Malvika Kaul, Christopher M. Barbieri, Daniel S. Pilch	2006	88
16	Human Topoisomerase I Poisoning by Protoberberines: Potential Roles for Both Drug−DNA and Drug−Enzyme Interactions Biochemistry ·Tsai‐Kun Li, Eleanor Bathory, Edmond J. LaVoie, A. R. Srinivasan, Wilma K. Olson, Ronald R. Sauers, Leroy F. Liu, Daniel S. Pilch	2000	83
17	Macrocyclic Pyridyl Polyoxazoles: Selective RNA and DNA G-Quadruplex Ligands as Antitumor Agents Journal of Medicinal Chemistry ·Suzanne G. Rzuczek, Daniel S. Pilch, Angela Liu, Leroy F. Liu, Edmond J. LaVoie, Joseph E. Rice	2010	79
18	Characterization of a Triple Helix-specific Ligand Journal of Molecular Biology ·Daniel S. Pilch, Michael J. Waring, Jian‐Sheng Sun, Michel Rougée, Chi-Hung Nguyen, Émile Bisagni, Thérèse Garestier, Claude Hélène	1993	76
19	Synthesis and G-quadruplex stabilizing properties of a series of oxazole-containing macrocycles Bioorganic & Medicinal Chemistry Letters ·Gurpreet Singh Minhas, Daniel S. Pilch, John E. Kerrigan, Edmond J. LaVoie, Joseph E. Rice	2006	70
20	G-Quadruplexes Induce Apoptosis in Tumor Cells Cancer Research ·Haiyan Qi, Chao‐Po Lin, Xuan Fu, Laurence M. Wood, Angela A. Liu, Yuan-Chin Tsai, Yongjie Chen, Christopher M. Barbieri, Daniel S. Pilch, Leroy F. Liu	2006	68

About Daniel S. Pilch

Daniel S. Pilch is a scholar working on Molecular Biology, Molecular Medicine, Genetics, Pharmacology and Infectious Diseases, having authored 86 papers that have together received 4.2k indexed citations. Recurring topics across this work include DNA and Nucleic Acid Chemistry (37 papers), RNA and protein synthesis mechanisms (23 papers), Cancer therapeutics and mechanisms (21 papers), Antibiotic Resistance in Bacteria (20 papers), Advanced biosensing and bioanalysis techniques (20 papers), Bacterial Genetics and Biotechnology (17 papers), RNA Interference and Gene Delivery (12 papers) and Antibiotics Pharmacokinetics and Efficacy (10 papers). The work is most often cited by research in Molecular Medicine (384 citations), Toxicology (171 citations), Molecular Biology (3.3k citations), Organic Chemistry (790 citations) and Microbiology (135 citations). Daniel S. Pilch has collaborated with scholars based in United States, France and United Kingdom. Frequent co-authors include Malvika Kaul, Edmond J. LaVoie, Christopher M. Barbieri, Kenneth J. Breslauer, Richard H. Shafer, Ajit K Parhi, John E. Kerrigan, Leroy F. Liu, Georg Plum and Joseph E. Rice. Their work appears in journals such as Biochemistry, Bioorganic & Medicinal Chemistry Letters, Journal of Molecular Biology, Journal of the American Chemical Society and Antimicrobial Agents and Chemotherapy.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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