D. E. Schmechel

27.2k citations

41 papers · 22.5k · 7 hit papers · h-index 28

Impact in

Physiology top 0.02%
- Alzheimer's disease research and treatments
Neurology top 0.1%
- Neuroinflammation and Neurodegeneration Mechanisms

Papers in

Molecular Biology 22
- S100 Proteins and Annexins 6
- Bioinformatics and Genomic Networks 4
Physiology 17
- Alzheimer's disease research and treatments 17

Co-authors: Ann M. Saunders (14 shared papers)Warren J. Strittmatter (11 shared papers)Allen D. Roses (13 shared papers)Jeffery M. Vance (7 shared papers)Elizabeth H. Corder (3 shared papers)P. C. Gaskell (2 shared papers)J. L. Haines (1 shared paper)Gary W. Small (1 shared paper)
Journals: Proceedings of the National Academy of Sciences (6 papers)Brain Research (3 papers)Environmental Health Perspectives (3 papers)Annals of the New York Academy of Sciences (2 papers)The Journal of Comparative Neurology (2 papers)
Partner nations: United States United Kingdom Czechia

In The Last Decade

D. E. Schmechel

41 papers receiving 21.6k citations

D. E. Schmechel's Hit Papers

7 papers align trajectories log scale

Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease 1994 · 1.5k citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

1994 Nature Genetics
1993 Neurology
1993 Proceedings of the National Academy of Sciences
1993 Science
1993 Proceedings of the National Academy of Sciences
1993 Proceedings of the National Academy of Sciences
1978 Proceedings of the National Academy of Sciences

Peers

Countries citing papers authored by D. E. Schmechel

Since Specialization

Citations

This map shows the geographic impact of D. E. Schmechel's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by D. E. Schmechel with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites D. E. Schmechel more than expected).

Fields of papers citing papers by D. E. Schmechel

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by D. E. Schmechel. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by D. E. Schmechel. The network helps show where D. E. Schmechel may publish in the future.

Co-authors

The 25 scholars most cited alongside D. E. Schmechel, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with D. E. Schmechel Line = papers co-authored together D. E. Schmechel links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Showing the 20 most-cited of 41 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families Science ·Elizabeth H. Corder, Ann M. Saunders, Warren J. Strittmatter, D. E. Schmechel, P. C. Gaskell, Gary W. Small, Allen D. Roses, J. L. Haines, Jeffery M. Vance Hit paper breakdown →	1993	7527
2	Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proceedings of the National Academy of Sciences ·Warren J. Strittmatter, Ann M. Saunders, D. E. Schmechel, M. A. Pericak‐Vance, Jan J. Enghild, Guy S. Salvesen, A D Roses Hit paper breakdown →	1993	3549
3	Association of apolipoprotein E allele ϵ4 with late‐onset familial and sporadic Alzheimer's disease Neurology ·Ann M. Saunders, Warren J. Strittmatter, D. E. Schmechel, Peter St George‐Hyslop, Jeffery M. Vance, Sun Hyung Joo, B.L. Rosi, James F. Gusella, D. R. Crapper-MacLachlan, Mark J. Alberts, Christine Hulette, Barbara J. Crain, Dmitry Goldgaber, Allen D. Roses Hit paper breakdown →	1993	3175
4	Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease Nature Genetics ·Elizabeth H. Corder, Ann M. Saunders, Neil Risch, Warren J. Strittmatter, D. E. Schmechel, P. C. Gaskell, Jacqueline Rimmler, P. A. Locke, P. M. Conneally, Ken Schmader, G. W. Small, Allen D. Roses, Jonathan L. Haines, Jeffery M. Vance Hit paper breakdown →	1994	1524
5	Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease. Proceedings of the National Academy of Sciences ·D. E. Schmechel, Ann M. Saunders, Warren J. Strittmatter, Barbara J. Crain, Christine M. Hulette, Sun Hyung Joo, Margaret A. Pericak‐Vance, Dmitry Goldgaber, Allen D. Roses Hit paper breakdown →	1993	1318
6	Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease. Proceedings of the National Academy of Sciences ·Warren J. Strittmatter, Karl H. Weisgraber, Daoyuan Huang, Li Dong, Guy S. Salvesen, Margaret A. Pericak‐Vance, D. E. Schmechel, Ann M. Saunders, Dmitry Goldgaber, Allen D. Roses Hit paper breakdown →	1993	1179
7	Identification of insulin in rat brain. Proceedings of the National Academy of Sciences ·Jana Havránková, D. E. Schmechel, Jesse Roth, M. Brownstein Hit paper breakdown →	1978	549
8	Apolipoprotein E ∈4 allele distributions in late-onset Alzheimer's disease and in other amyloid-forming diseases The Lancet ·Ann M. Saunders, Allen D. Roses, Jeffery M. Vance, Kenneth C. Dole, Warren J. Strittmatter, D. E. Schmechel, Mari H. Szymanski, N McCown, M. Manwaring, Ken Schmader, John C.S. Breitner, Dmitry Goldgaber, M D Benson, Lev G. Goldfarb, W. T. BROWN	1993	438
9	Isoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer disease. Proceedings of the National Academy of Sciences ·Warren J. Strittmatter, Ann M. Saunders, Michel Goedert, Karl H. Weisgraber, Li Dong, Ross Jakes, Daoyuan Huang, Jeffery M. Vance, D. E. Schmechel, Allen D. Roses	1994	414
10	Neuron Specific Enolase, A Clinically Useful Marker for Neurons and Neuroendocrine Cells Annual Review of Neuroscience ·Paul J. Marangos, D. E. Schmechel	1987	374
11	Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3. Journal of Clinical Investigation ·David A. Sanan, Karl H. Weisgraber, Stephen J. Russell, Robert W. Mahley, David Huang, Ann M. Saunders, D. E. Schmechel, Thomas Wısnıewskı, Blas Frangione, Allen D. Roses	1994	358
12	Neurons switch from non-neuronal enolase to neuron-specific enolase during differentiation Brain Research ·D. E. Schmechel, Milton Brightman, Paul J. Marangos	1980	320
13	Apolipoprotein E allele-dependent pathogenesis: A model for age-related retinal degeneration Proceedings of the National Academy of Sciences ·Goldis Malek, Lincoln V. Johnson, Brian E. Mace, Peter Saloupis, D. E. Schmechel, Douglas L. Rickman, Cynthia A. Toth, Patrick M. Sullivan, Catherine Bowes Rickman	2005	241
14	MEASUREMENT OF NEURON‐SPECIFIC (NSE) AND NON‐NEURONAL (NNE) ISOENZYMES OF ENOLASE IN RAT, MONKEY AND HUMAN NERVOUS TISSUE Journal of Neurochemistry ·Paul J. Marangos, D. E. Schmechel, Alexandra M. Parma, Reena L. Clark, Frederick K. Goodwin	1979	209
15	Variability in the terminations of GABAergic chandelier cell axons on initial segments of pyramidal cell axons in the monkey sensory‐motor cortex The Journal of Comparative Neurology ·Javier DeFelipe, S.H.C. Hendry, E.G. Jones, D. E. Schmechel	1985	201
16	Kinetic and hydrodynamic studies of the complex of proflavine with poly A·poly U Biopolymers ·D. E. Schmechel, Donald M. Crothers	1971	146
17	Altered immune responses in apolipoprotein E-deficient mice Journal of Lipid Research ·Daniel T. Laskowitz, D.M. Lee, D. E. Schmechel, Herman F. Staats	2000	130
18	Glutamic acid decarboxylase and somatostatin immunoreactivities in rat visual cortex The Journal of Comparative Neurology ·Chia‐Sheng Lin, Shao‐Ming Lu, D. E. Schmechel	1986	122
19	APOE and the regulation of microglial nitric oxide production: a link between genetic risk and oxidative stress Neurobiology of Aging ·Carol A. Colton, Candice M. Brown, Donald N. Cook, Leila K. Needham, Qin Xu, Meggan Czapiga, Alec Saunders, D. E. Schmechel, Khalid Rasheed, Michael P. Vitek	2002	117
20	AF64A-induced working memory impairment: behavioral, neurochemical and histological correlates Brain Research ·James J. Chrobak, Israel Hanin, D. E. Schmechel, Thomas J. Walsh	1988	101

About D. E. Schmechel

D. E. Schmechel is a scholar working on Molecular Biology, Physiology, Cellular and Molecular Neuroscience, Psychiatry and Mental health and Pharmacology, having authored 41 papers that have together received 22.5k indexed citations. Recurring topics across this work include Alzheimer's disease research and treatments (17 papers), Neuroscience and Neuropharmacology Research (7 papers), S100 Proteins and Annexins (6 papers), Cholinesterase and Neurodegenerative Diseases (5 papers), Dementia and Cognitive Impairment Research (5 papers), Nuclear Receptors and Signaling (4 papers), Bioinformatics and Genomic Networks (4 papers) and Marine Toxins and Detection Methods (4 papers). The work is most often cited by research in Physiology (12.4k citations), Neurology (2.5k citations), Psychiatry and Mental health (3.9k citations), Biological Psychiatry (486 citations) and Cellular and Molecular Neuroscience (3.6k citations). D. E. Schmechel has collaborated with scholars based in United States, United Kingdom and Czechia. Frequent co-authors include Ann M. Saunders, Warren J. Strittmatter, Allen D. Roses, Jeffery M. Vance, Elizabeth H. Corder, P. C. Gaskell, J. L. Haines, Gary W. Small, Guy S. Salvesen and Dmitry Goldgaber. Their work appears in journals such as Proceedings of the National Academy of Sciences, Brain Research, Environmental Health Perspectives, Annals of the New York Academy of Sciences and The Journal of Comparative Neurology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

D. E. Schmechel

Impact in

Papers in i

In The Last Decade

D. E. Schmechel

D. E. Schmechel's Hit Papers

Peers

Countries citing papers authored by D. E. Schmechel

Fields of papers citing papers by D. E. Schmechel

All Works

About D. E. Schmechel

Explore authors with similar magnitude of impact

Papers in