C. Peter Downes

31.0k citations
200 papers · 27.6k · 10 hit papers · h-index 79

Impact in

  • Cell Biology top 0.05%
    • Cellular transport and secretion
    • Protein Kinase Regulation and GTPase Signaling
    • PI3K/AKT/mTOR signaling in cancer
    • Receptor Mechanisms and Signaling
    • Metabolism, Diabetes, and Cancer
    • Ion channel regulation and function

Papers in

    • Protein Kinase Regulation and GTPase Signaling 99
    • PI3K/AKT/mTOR signaling in cancer 53
    • Lipid Membrane Structure and Behavior 13
    • Metabolism, Diabetes, and Cancer 12
    • Receptor Mechanisms and Signaling 10
    • Cellular transport and secretion 59

C. Peter Downes

200 papers receiving 26.7k citations

C. Peter Downes's Hit Papers

The TSC1-2 tumor suppressor controls insulin–PI3K signaling via regulation of IRS proteins 2004 · 959 citations
9590+15+30Years since publication50010001.5k2.0k

Peers

C. Peter Downes
Comparison fields: 5 of 147
  • Cell Biology 5.5k
  • Molecular Biology 19.5k
  • Physiology 1.1k
  • Cellular and Molecular Neuroscience 3.8k
  • Genetics 1.7k
Replace Robin F. Irvine with:
Robin F. Irvine United Kingdom
Brian A. Hemmings Switzerland
Tamás Balla United States
Enrique Rozengurt United Kingdom
Ushio Kikkawa Japan
Jacopo Meldolesi Italy
Joseph Avruch United States
Wouter H. Moolenaar Netherlands
James R. Woodgett Canada
John H. Exton United States
C. Peter Downes relative to Robin F. Irvine United Kingdom Robin F. Irvine's profile →
Citations per field
00.5×1.5×1.9×
Robin F. Irvine · 1×
Citations per year

Countries citing papers authored by C. Peter Downes

Since Specialization
Citations

This map shows the geographic impact of C. Peter Downes's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by C. Peter Downes with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites C. Peter Downes more than expected).

Fields of papers citing papers by C. Peter Downes

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by C. Peter Downes. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by C. Peter Downes. The network helps show where C. Peter Downes may publish in the future.

Co-authors

The 25 scholars most cited alongside C. Peter Downes, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with C. Peter Downes Line = papers co-authored together C. Peter Downes links everyone, so they are left out of the graph.

All Works

20 of 20 papers shown

Showing the 20 most-cited of 200 papers — load more, or switch the sort, to bring in the rest.

#Work
1
Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα
Hit paper breakdown →
19972411
2
Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands
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19821997
3
Changes in the levels of inositol phosphates after agonist-dependent hydrolysis of membrane phosphoinositides
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19831876
4
The lipid phosphatase activity of PTEN is critical for its tumor supressor function
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19981009
5
The TSC1-2 tumor suppressor controls insulin–PI3K signaling via regulation of IRS proteins
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2004959
6
Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate
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1988908
7
Neural and developmental actions of lithium: A unifying hypothesis
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1989876
8
The polyphosphoinositide phosphodiesterase of erythrocyte membranes
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1981584
9
Rapid breakdown of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate in rat hepatocytes stimulated by vasopressin and other Ca2+-mobilizing hormones
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1983515
10
The inositol trisphosphate phosphomonoesterase of the human erythrocyte membrane
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1982512
11 1981468
12 2000461
13 1985428
14 1999387
15 2002376
16 2004372
17 2002353
18 1999324
19 2001323
20 2002303

About C. Peter Downes

C. Peter Downes is a scholar working on Molecular Biology, Cell Biology, Surgery, Physiology and Cellular and Molecular Neuroscience, having authored 200 papers that have together received 27.6k indexed citations. Recurring topics across this work include Protein Kinase Regulation and GTPase Signaling (99 papers), Cellular transport and secretion (59 papers), PI3K/AKT/mTOR signaling in cancer (53 papers), Pancreatic function and diabetes (29 papers), Erythrocyte Function and Pathophysiology (14 papers), Lipid Membrane Structure and Behavior (13 papers), Metabolism, Diabetes, and Cancer (12 papers) and Receptor Mechanisms and Signaling (10 papers). The work is most often cited by research in Cell Biology (5.5k citations), Molecular Biology (19.5k citations), Physiology (1.1k citations), Cellular and Molecular Neuroscience (3.8k citations) and Genetics (1.7k citations). C. Peter Downes has collaborated with scholars based in United Kingdom, United States and Canada. Frequent co-authors include Michael J. Berridge, Michael R. Hanley, Nicholas R. Leslie, Dario R. Alessi, Robert H. Michell, Robin F. Irvine, Stephen R. James, Ian H. Batty, Piers R. J. Gaffney and Andrew B. Holmes. Their work appears in journals such as Biochemical Journal, Journal of Biological Chemistry, Biochemical Society Transactions, Current Biology and Journal of Neurochemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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