Brian J. Smith

19.8k citations

246 papers · 14.0k · 4 hit papers · h-index 59

Impact in

Molecular Biology top 0.5%
- Cell death mechanisms and regulation
- Chemical Synthesis and Analysis
- RNA Interference and Gene Delivery
- Nicotinic Acetylcholine Receptors Study
- Ion channel regulation and function
Biophysics top 0.5%

Papers in

Molecular Biology 91
- Cell death mechanisms and regulation 15
- Nicotinic Acetylcholine Receptors Study 13
Organic Chemistry 47
- Free Radicals and Antioxidants 14

Co-authors: Leo Radom (29 shared papers)Peter M. Colman (27 shared papers)David C.S. Huang (9 shared papers)Catherine L. Day (2 shared papers)Mark G. Hinds (2 shared papers)Jerry M. Adams (3 shared papers)TJ Lasserson (2 shared papers)John Wright (2 shared papers)
Journals: Journal of Biological Chemistry (13 papers)Journal of the American Chemical Society (12 papers)Chemical Physics Letters (9 papers)The Journal of Physical Chemistry (7 papers)Biochemistry (7 papers)
Partner nations: Australia United States United Kingdom

In The Last Decade

Brian J. Smith

241 papers receiving 13.7k citations

Brian J. Smith's Hit Papers

align trajectories log scale

Bax Crystal Structures Reveal How BH3 Domains Activate Bax and Nucleate Its Oligomerization to Induce Apoptosis 2013 · 452 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2013 Cell
2006 Cochrane Database of Systematic Reviews
2005 Molecular Cell
1990 The Journal of Chemical Physics

Peers

Countries citing papers authored by Brian J. Smith

Since Specialization

Citations

This map shows the geographic impact of Brian J. Smith's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Brian J. Smith with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Brian J. Smith more than expected).

Fields of papers citing papers by Brian J. Smith

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Brian J. Smith. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Brian J. Smith. The network helps show where Brian J. Smith may publish in the future.

Co-authors

The 25 scholars most cited alongside Brian J. Smith, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Brian J. Smith Line = papers co-authored together Brian J. Smith links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 246 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Differential Targeting of Prosurvival Bcl-2 Proteins by Their BH3-Only Ligands Allows Complementary Apoptotic Function Molecular Cell ·Lin Chen, Simon N. Willis, Andrew H. Wei, Brian J. Smith, Jamie I. Fletcher, Mark G. Hinds, Peter M. Colman, Catherine L. Day, Jerry M. Adams, David C.S. Huang Hit paper breakdown →	2005	1482
2	Continuous positive airways pressure for obstructive sleep apnoea in adults Cochrane Database of Systematic Reviews ·TL Giles, TJ Lasserson, Brian J. Smith, John White, John Wright, Christopher J Cates Hit paper breakdown →	2006	694
3	Bax Crystal Structures Reveal How BH3 Domains Activate Bax and Nucleate Its Oligomerization to Induce Apoptosis Cell ·Peter E. Czabotar, Dana Westphal, Grant Dewson, Stephen Ma, Colin Hockings, W. Douglas Fairlie, Erinna F. Lee, Shenggen Yao, A.Y. Robin, Brian J. Smith, David C.S. Huang, Ruth M. Kluck, Jerry M. Adams, Peter M. Colman Hit paper breakdown →	2013	452
4	The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1β production Proceedings of the National Academy of Sciences ·Jae Jin Chae, Geryl Wood, Seth L. Masters, Katharina Richard, Grace Park, Brian J. Smith, Daniel L. Kastner	2006	420
5	Structural insights into the degradation of Mcl-1 induced by BH3 domains Proceedings of the National Academy of Sciences ·Peter E. Czabotar, Erinna F. Lee, Mark F. van Delft, Catherine L. Day, Brian J. Smith, David C.S. Huang, W. Douglas Fairlie, Mark G. Hinds, Peter M. Colman	2007	376
6	A newly discovered protein export machine in malaria parasites Nature ·Tania F. de Koning‐Ward, Paul R. Gilson, Justin A. Boddey, Melanie Rug, Brian J. Smith, Anthony T. Papenfuss, Paul R. Sanders, Rachel J. Lundie, Alexander G. Maier, Alan F. Cowman, Brendan S. Crabb	2009	369
7	Continuous positive airways pressure for obstructive sleep apnoea in adults Cochrane Database of Systematic Reviews ·TL Giles, TJ Lasserson, Brian J. Smith, John White, John Wright, Christopher J Cates	2006	299
8	How insulin engages its primary binding site on the insulin receptor Nature ·John G. Menting, Jonathan Whittaker, Mai B. Margetts, Linda Whittaker, G.K.-W. Kong, Brian J. Smith, Christopher J.E. Watson, Lenka Žáková, Emília Kletvíková, Jiřı́ Jiráček, Shu Jin Chan, Donald F. Steiner, Guy Dodson, A.M. Brzozowski, Michael A. Weiss, Colin W. Ward, Michael C. Lawrence	2013	296
9	Raman Spectroscopic Method for Identification of Clinically Relevant Microorganisms Growing on Solid Culture Medium Analytical Chemistry ·K. Maquelin, Lin‐P'ing Choo‐Smith, T. van Vreeswijk, Hubert P. Endtz, Brian J. Smith, Robert D. Bennett, Hajo A. Bruining, Gerwin J. Puppels	1999	247
10	Transition structures for the interchange of hydrogen atoms within the water dimer The Journal of Chemical Physics ·Brian J. Smith, David J. Swanton, John A. Pople, Henry F. Schaefer, Leo Radom Hit paper breakdown →	1990	209
11	Gaussian-2 (G2) theory: Reduced basis set requirements The Journal of Chemical Physics ·Larry A. Curtiss, Paul C. Redfern, Brian J. Smith, Leo Radom	1996	208
12	Assigning absolute values to proton affinities: a differentiation between competing scales Journal of the American Chemical Society ·Brian J. Smith, Leo Radom	1993	205
13	Infrared Spectral Interpretation Brian J. Smith	2018	193
14	The Structure of the Fusion Glycoprotein of Newcastle Disease Virus Suggests a Novel Paradigm for the Molecular Mechanism of Membrane Fusion Structure ·Lin Chen, Jeffrey J. Gorman, (unknown), Lynne J. Lawrence, P.A. Tulloch, Brian J. Smith, Peter M. Colman, Michael C. Lawrence	2001	192
15	Anti-CD20 monoclonal antibody with enhanced affinity for CD16 activates NK cells at lower concentrations and more effectively than rituximab Blood ·J. A. Bowles, Siao‐Yi Wang, Brian K. Link, Barrett W. Allan, Gregory Beuerlein, Mary-Ann Campbell, David M. Marquis, Brian Ondek, James E. Wooldridge, Brian J. Smith, James B. Breitmeyer, George J. Weiner	2006	171
16	Calculation of Proton Affinities Using the G2(MP2,SVP) Procedure The Journal of Physical Chemistry ·Brian J. Smith, Leo Radom	1995	164
17	Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis Nature Communications ·Emma J. Petrie, Jarrod J. Sandow, Annette V. Jacobsen, Brian J. Smith, Michael D. W. Griffin, Isabelle S. Lucet, Weiwen Dai, Samuel N. Young, Maria C. Tanzer, Ahmad Z. Wardak, Lung‐Yu Liang, Angus D. Cowan, Joanne M. Hildebrand, Wilhelmus J. A. Kersten, Guillaume Lessène, John Silke, Peter E. Czabotar, Andrew I. Webb, James M. Murphy	2018	151
18	High‐Resolution Structural Characterization of a Helical α/β‐Peptide Foldamer Bound to the Anti‐Apoptotic Protein Bcl‐x_L Angewandte Chemie International Edition ·Erinna F. Lee, Jack Sadowsky, Brian J. Smith, Peter E. Czabotar, Kimberly J. Peterson‐Kaufman, Peter M. Colman, Samuel H. Gellman, W. Douglas Fairlie	2009	140
19	Structure/Function Characterization of μ-Conotoxin KIIIA, an Analgesic, Nearly Irreversible Blocker of Mammalian Neuronal Sodium Channels Journal of Biological Chemistry ·Min-Min Zhang, Brad R. Green, Philip Catlin, Brian Fiedler, Layla Azam, Ashley T. Chadwick, Heinrich Terlau, Jeffrey R. McArthur, Robert J. French, Josef Gulyas, Jean Rivier, Brian J. Smith, Raymond S. Norton, Baldomero M. Olivera, Doju Yoshikami, Grzegorz Bułaj	2007	132
20	Domain Reorientation and Rotation of an Intracellular Assembly Regulate Conduction in Kir Potassium Channels Cell ·Oliver B. Clarke, Alessandro T. Caputo, Adam P. Hill, Jamie I. Vandenberg, Brian J. Smith, Jacqueline M. Gulbis	2010	132

About Brian J. Smith

Brian J. Smith is a scholar working on Molecular Biology, Organic Chemistry, Atomic and Molecular Physics, and Optics, Public Health, Environmental and Occupational Health and Physical and Theoretical Chemistry, having authored 246 papers that have together received 14.0k indexed citations. Recurring topics across this work include Advanced Chemical Physics Studies (30 papers), Cell death mechanisms and regulation (15 papers), Spectroscopy and Quantum Chemical Studies (15 papers), Free Radicals and Antioxidants (14 papers), Nicotinic Acetylcholine Receptors Study (13 papers), Malaria Research and Control (12 papers), Molecular Spectroscopy and Structure (12 papers) and Spectroscopy Techniques in Biomedical and Chemical Research (12 papers). The work is most often cited by research in Molecular Biology (6.5k citations), Biophysics (553 citations), Organic Chemistry (1.9k citations), Immunology (1.3k citations) and Physical and Theoretical Chemistry (590 citations). Brian J. Smith has collaborated with scholars based in Australia, United States and United Kingdom. Frequent co-authors include Leo Radom, Peter M. Colman, David C.S. Huang, Catherine L. Day, Mark G. Hinds, Jerry M. Adams, TJ Lasserson, John Wright, Christopher J Cates and John White. Their work appears in journals such as Journal of Biological Chemistry, Journal of the American Chemical Society, Chemical Physics Letters, The Journal of Physical Chemistry and Biochemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Brian J. Smith

Brian J. Smith's Hit Papers

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All Works

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