Beth A. Fleck

1.1k citations

52 papers · 947 · h-index 19

Impact in

Endocrine and Autonomic Systems top 2%
- Regulation of Appetite and Obesity
Nutrition and Dietetics top 2%
- Biochemical Analysis and Sensing Techniques

Papers in

Nutrition and Dietetics 30
- Biochemical Analysis and Sensing Techniques 30
Endocrine and Autonomic Systems 29
- Regulation of Appetite and Obesity 29

Co-authors: Sam R.J. Hoare (16 shared papers)Alan C. Foster (30 shared papers)Chen Chen (26 shared papers)Joe A. Tran (25 shared papers)Fábio C. Tucci (26 shared papers)John Saunders (23 shared papers)Stacy Markison (14 shared papers)Dragan Marinković (20 shared papers)
Journals: Bioorganic & Medicinal Chemistry Letters (28 papers)Journal of Medicinal Chemistry (6 papers)Journal of Pharmacology and Experimental Therapeutics (2 papers)Biochemistry (2 papers)Bioorganic & Medicinal Chemistry (2 papers)
Partner nations: United States United Kingdom

In The Last Decade

Beth A. Fleck

52 papers receiving 906 citations

Peers

Countries citing papers authored by Beth A. Fleck

Since Specialization

Citations

This map shows the geographic impact of Beth A. Fleck's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Beth A. Fleck with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Beth A. Fleck more than expected).

Fields of papers citing papers by Beth A. Fleck

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Beth A. Fleck. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Beth A. Fleck. The network helps show where Beth A. Fleck may publish in the future.

Co-authors

The 25 scholars most cited alongside Beth A. Fleck, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Beth A. Fleck Line = papers co-authored together Beth A. Fleck links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 52 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	The Regulation of Feeding and Metabolic Rate and the Prevention of Murine Cancer Cachexia with a Small-Molecule Melanocortin-4 Receptor Antagonist Endocrinology ·Stacy Markison, Alan C. Foster, Chen Chen, Gregor Brookhart, Amy Hesse, Sam R.J. Hoare, Beth A. Fleck, Brock Brown, Daniel L. Marks	2005	81
2	Identification of Novel HSP90α/β Isoform Selective Inhibitors Using Structure-Based Drug Design. Demonstration of Potential Utility in Treating CNS Disorders such as Huntington’s Disease Journal of Medicinal Chemistry ·Justin T. Ernst, Timothy D. Neubert, Michael C. Liu, Samuel Sperry, Harmon Zuccola, Amy Turnbull, Beth A. Fleck, William J. Kargo, Lisa Woody, Peggy Chiang, Dao Tran, Weichao Chen, Phillip W. Snyder, Timothy Alcacio, Azin Nezami, James M. Reynolds, Khisal A. Alvi, Lance Goulet, Dean Stamos	2014	58
3	Binding Kinetics Redefine the Antagonist Pharmacology of the Corticotropin-Releasing Factor Type 1 Receptor Journal of Pharmacology and Experimental Therapeutics ·Beth A. Fleck, Sam R.J. Hoare, Rebecca R. Pick, Margaret Bradbury, Dimitri E. Grigoriadis	2012	54
4	Functional Selectivity of Melanocortin 4 Receptor Peptide and Nonpeptide Agonists: Evidence for Ligand-Specific Conformational States Journal of Pharmacology and Experimental Therapeutics ·Sarah A. Nickolls, Beth A. Fleck, Sam R.J. Hoare, R. Maki	2005	42
5	Studies on the structure–activity relationship of bicifadine analogs as monoamine transporter inhibitors Bioorganic & Medicinal Chemistry Letters ·Mingzhu Zhang, Florence Jovic, Troy Vickers, Brian Dyck, Junko Tamiya, Jonathan Grey, Joe A. Tran, Beth A. Fleck, Rebecca R. Pick, Alan C. Foster, Chen Chen	2008	31
6	Synthesis and structure–activity relationships of selective norepinephrine reuptake inhibitors (sNRI) with a heterocyclic ring constraint Bioorganic & Medicinal Chemistry Letters ·Sarah Hudson, Mehrak Kiankarimi, Wendy Eccles, Yalda Mostofi, Marc J. Genicot, Wesley Dwight, Beth A. Fleck, Kathleen R. Gogas, Warren S. Wade	2008	31
7	Potent and orally active non-peptide antagonists of the human melanocortin-4 receptor based on a series of trans-2-disubstituted cyclohexylpiperazines Bioorganic & Medicinal Chemistry Letters ·Fábio C. Tucci, Nicole S. White, Stacy Markison, Margaret Joppa, Joe A. Tran, Beth A. Fleck, Ajay Madan, Brian Dyck, Jessica Parker, Joseph Pontillo, L.M. Arellano, Dragan Marinković, Wanlong Jiang, Caroline W. Chen, Kathleen R. Gogas, Val S. Goodfellow, John Saunders, Alan C. Foster, Chen Chen	2005	30
8	Kinetics of nonpeptide antagonist binding to the human gonadotropin-releasing hormone receptor: Implications for structure–activity relationships and insurmountable antagonism Biochemical Pharmacology ·Susan K. Sullivan, Sam R.J. Hoare, Beth A. Fleck, Yunfei Zhu, Christopher E. Heise, R. Scott Struthers, Paul D. Crowe	2006	30
9	4-{(2R)-[3-Aminopropionylamido]-3-(2,4-dichlorophenyl)propionyl}-1-{2-[(2-thienyl)ethylaminomethyl]phenyl}piperazine as a Potent and Selective Melanocortin-4 Receptor AntagonistDesign, Synthesis, and Characterization Journal of Medicinal Chemistry ·Chen Chen, Joseph Pontillo, Beth A. Fleck, Yinghong Gao, Jenny Wen, Joe A. Tran, Fábio C. Tucci, Dragan Marinković, Alan C. Foster, John Saunders	2004	28
10	The importance of target binding kinetics for measuring target binding affinity in drug discovery: a case study from a CRF1 receptor antagonist program Drug Discovery Today ·Sam R.J. Hoare, Beth A. Fleck, John P. Williams, Dimitri E. Grigoriadis	2019	27
11	Body Weight Regulation by Selective MC4 Receptor Agonists and Antagonists Annals of the New York Academy of Sciences ·Alan C. Foster, Margaret Joppa, Stacy Markison, K.R. Gogas, Beth A. Fleck, Brian J. Murphy, Meira Wolff, Mary J. Cismowski, Nicholas Ling, Val S. Goodfellow, Chen Chen, John Saunders, Paul Conlon	2003	25
12	Allosteric Ligands for the Corticotropin Releasing Factor Type 1 Receptor Modulate Conformational States Involved in Receptor Activation Molecular Pharmacology ·Sam R.J. Hoare, Beth A. Fleck, Raymond S. Gross, Paul D. Crowe, John P. Williams, Dimitri E. Grigoriadis	2008	24
13	Discovery of a potent, selective, and less flexible selective norepinephrine reuptake inhibitor (sNRI) Bioorganic & Medicinal Chemistry Letters ·Dongpei Wu, Joseph Pontillo, Brett Ching, Sarah Hudson, Yinghong Gao, Beth A. Fleck, Kathleen R. Gogas, Warren S. Wade	2008	24
14	Piperazinebenzylamines as potent and selective antagonists of the human melanocortin-4 receptor Bioorganic & Medicinal Chemistry Letters ·Joseph Pontillo, Joseph A. Tran, Beth A. Fleck, Dragan Marinković, Melissa Arellano, Fábio C. Tucci, Marion Lanier, Jodie Nelson, Jessica Parker, John Saunders, Brian J. Murphy, Alan C. Foster, Chen Chen	2004	24
15	Molecular Interactions of Nonpeptide Agonists and Antagonists with the Melanocortin-4 Receptor Biochemistry ·Beth A. Fleck, Chen Chen, Weidong Yang, Rajesh Huntley, Stacy Markison, Sarah A. Nickolls, Alan C. Foster, Sam R.J. Hoare	2005	24
16	Arylpropionylpiperazines as antagonists of the human melanocortin-4 receptor Bioorganic & Medicinal Chemistry Letters ·Wanlong Jiang, Fábio C. Tucci, Caroline W. Chen, Melissa Arellano, Joe A. Tran, Nicole S. White, Dragan Marinkovic, Joseph Pontillo, Beth A. Fleck, Jenny Wen, John Saunders, Ajay Madan, Alan C. Foster, Chen Chen	2006	22
17	A potent and selective nonpeptide antagonist of the melanocortin-4 receptor induces food intake in satiated mice Bioorganic & Medicinal Chemistry Letters ·Joseph Pontillo, Joseph A. Tran, Stacy Markison, Margaret Joppa, Beth A. Fleck, Dragan Marinković, Melissa Arellano, Fábio C. Tucci, Marion Lanier, Jodie Nelson, John Saunders, Sam R.J. Hoare, Alan C. Foster, Chen Chen	2005	21
18	Structure–activity relationships of piperazinebenzylamines as potent and selective agonists of the human melanocortin-4 receptor Bioorganic & Medicinal Chemistry Letters ·Joseph Pontillo, Joseph A. Tran, Melissa Arellano, Beth A. Fleck, Rajesh Huntley, Dragan Marinković, Marion Lanier, Jodie Nelson, Jessica Parker, John Saunders, Fábio C. Tucci, Wanlong Jiang, Caroline W. Chen, (unknown), Nicole S. White, Alan C. Foster, (unknown), (unknown)	2004	21
19	Pharmacological and pharmacokinetic characterization of 2-piperazine-α-isopropyl benzylamine derivatives as melanocortin-4 receptor antagonists Bioorganic & Medicinal Chemistry ·Chen Chen, Fábio C. Tucci, Wanlong Jiang, Joe A. Tran, Beth A. Fleck, Sam R.J. Hoare, Jenny Wen, Takung Chen, Michael Johns, Stacy Markison, Alan C. Foster, Dragan Marinković, Caroline W. Chen, Melissa Arellano, J. S. Harman, John Saunders, Haig Bozigian, Daniel L. Marks	2008	19
20	Identification of 1S,2R-milnacipran analogs as potent norepinephrine and serotonin transporter inhibitors Bioorganic & Medicinal Chemistry Letters ·Junko Tamiya, Brian Dyck, Mingzhu Zhang, Kasey Phan, Beth A. Fleck, Anna Aparicio, Florence Jovic, Joe A. Tran, Troy Vickers, Jonathan Grey, Alan C. Foster, Chen Chen	2008	18

About Beth A. Fleck

Beth A. Fleck is a scholar working on Nutrition and Dietetics, Endocrine and Autonomic Systems, Molecular Biology, Cell Biology and Cellular and Molecular Neuroscience, having authored 52 papers that have together received 947 indexed citations. Recurring topics across this work include Biochemical Analysis and Sensing Techniques (30 papers), Regulation of Appetite and Obesity (29 papers), melanin and skin pigmentation (16 papers), Receptor Mechanisms and Signaling (13 papers), Pharmacological Receptor Mechanisms and Effects (8 papers), Neuroscience and Neuropharmacology Research (6 papers), Adipose Tissue and Metabolism (3 papers) and Coordination Chemistry and Organometallics (3 papers). The work is most often cited by research in Endocrine and Autonomic Systems (381 citations), Nutrition and Dietetics (332 citations), Behavioral Neuroscience (35 citations), Cell Biology (158 citations) and Biological Psychiatry (19 citations). Beth A. Fleck has collaborated with scholars based in United States and United Kingdom. Frequent co-authors include Sam R.J. Hoare, Alan C. Foster, Chen Chen, Joe A. Tran, Fábio C. Tucci, John Saunders, Stacy Markison, Dragan Marinković, Dimitri E. Grigoriadis and Joseph Pontillo. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Journal of Medicinal Chemistry, Journal of Pharmacology and Experimental Therapeutics, Biochemistry and Bioorganic & Medicinal Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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