Bert Spenkelink

1.6k citations

36 papers · 1.2k · h-index 19

Impact in

Biochemistry top 5%
- Phytochemicals and Antioxidant Activities
- Antioxidant Activity and Oxidative Stress
Health, Toxicology and Mutagenesis top 5%
- Toxic Organic Pollutants Impact
- Effects and risks of endocrine disrupting chemicals
- Environmental Toxicology and Ecotoxicology

Papers in

Health, Toxicology and Mutagenesis 10
- Effects and risks of endocrine disrupting chemicals 6
- Environmental Toxicology and Ecotoxicology 4
- Toxic Organic Pollutants Impact 3
Cancer Research 10
- Carcinogens and Genotoxicity Assessment 10

Co-authors: Ivonne M.C.M. Rietjens (26 shared papers)Ans Punt (11 shared papers)Marelle G. Boersma (4 shared papers)Laura de Haan (6 shared papers)Nicole H.P. Cnubben (2 shared papers)Jelmer J. van Zanden (2 shared papers)G.M. Alink (4 shared papers)Peter J. van Bladeren (8 shared papers)
Journals: Archives of Toxicology (5 papers)Toxicology in Vitro (2 papers)Chemico-Biological Interactions (2 papers)Environmental Toxicology and Chemistry (2 papers)Journal of Agricultural and Food Chemistry (2 papers)
Partner nations: Netherlands Thailand Switzerland

In The Last Decade

Bert Spenkelink

35 papers receiving 1.2k citations

Peers

Countries citing papers authored by Bert Spenkelink

Since Specialization

Citations

This map shows the geographic impact of Bert Spenkelink's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Bert Spenkelink with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Bert Spenkelink more than expected).

Fields of papers citing papers by Bert Spenkelink

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Bert Spenkelink. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Bert Spenkelink. The network helps show where Bert Spenkelink may publish in the future.

Co-authors

The 25 scholars most cited alongside Bert Spenkelink, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Bert Spenkelink Line = papers co-authored together Bert Spenkelink links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 36 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	The pro-oxidant chemistry of the natural antioxidants vitamin C, vitamin E, carotenoids and flavonoids Environmental Toxicology and Pharmacology ·Ivonne M.C.M. Rietjens, Marelle G. Boersma, Laura de Haan, Bert Spenkelink, Hanem M. Awad, Nicole H.P. Cnubben, Jelmer J. van Zanden, Hester van der Woude, G.M. Alink, J.H. Koeman	2002	304
2	Interplay between MRP Inhibition and Metabolism of MRP Inhibitors: The Case of Curcumin Chemical Research in Toxicology ·Heleen M. Wortelboer, Mustafa Usta, Astrid E. van der Velde, Marelle G. Boersma, Bert Spenkelink, Jelmer J. van Zanden, Ivonne M.C.M. Rietjens, Peter J. van Bladeren, Nicole H.P. Cnubben	2003	99
3	Biochemical and toxic effects of polychlorinated biphenyls (PCBs), dibenzo-P-dioxins (PCDDs) and dibenzofurans (PCDFs) in the cormorant (phalacrocorax carbo) after in ovo exposure Environmental Toxicology and Chemistry ·Martin van den Berg, Bart L.H.J. Craane, Theo L. Sinnige, Sijmen VanMourik, Marten Van Der Gaag, Ineke J. Lutke-Schipholt, Bert Spenkelink, Abraham Brouwer, S. Dirksen, Theo Boudewun	1994	94
4	Combining in vitro embryotoxicity data with physiologically based kinetic (PBK) modelling to define in vivo dose–response curves for developmental toxicity of phenol in rat and human Archives of Toxicology ·Marije Strikwold, Bert Spenkelink, R.A. Woutersen, Ivonne M.C.M. Rietjens, Ans Punt	2013	61
5	Microfluidic chip for culturing intestinal epithelial cell layers: Characterization and comparison of drug transport between dynamic and static models Toxicology in Vitro ·Kornphimol Kulthong, Loes P. M. Duivenvoorde, Huiyi Sun, Samuel Confederat, Jiaqing Wu, Bert Spenkelink, Laura de Haan, Victor Marin, Meike van der Zande, Hans Bouwmeester	2020	60
6	Conversion of major soy isoflavone glucosides and aglycones in in vitro intestinal models Molecular Nutrition & Food Research ·Mohammed Ariful Islam, Ans Punt, Bert Spenkelink, Albertinka J. Murk, F.X.R. van Leeuwen, Ivonne M.C.M. Rietjens	2013	46
7	BIOCHEMICAL AND TOXIC EFFECTS OF POLYCHLORINATED BIPHENYLS (PCBs), DIBENZO-p-DIOXINS (PCDDs) AND DIBENZOFURANS (PCDFs) IN THE CORMORANT (PHALACROCORAX CARBO) AFTER IN OVO EXPOSURE Environmental Toxicology and Chemistry ·Martin van den Berg, Bart L.H.J. Craane, Theo L. Sinnige, Sijmen van Mourik, S. Dirksen, T.J. Boudewijn, Marten van der Gaag, Ineke J. Lutke-Schipholt, Bert Spenkelink, Abraham Brouwer	1994	44
8	Stereoselective Conjugation, Transport and Bioactivity ofS- andR-Hesperetin Enantiomers in Vitro Journal of Agricultural and Food Chemistry ·Walter Brand, Jia Shao, (unknown), Kathelijn N. van Elk, Bert Spenkelink, Laura H.J. de Haan, Maarit J. Rein, Fabiola Dionisi, Gary Williamson, Peter J. van Bladeren, Ivonne M.C.M. Rietjens	2010	43
9	Integrating in vitro data and physiologically based kinetic (PBK) modelling to assess the in vivo potential developmental toxicity of a series of phenols Archives of Toxicology ·Marije Strikwold, Bert Spenkelink, Laura H.J. de Haan, R.A. Woutersen, Ans Punt, Ivonne M.C.M. Rietjens	2016	39
10	Physiologically based kinetic modeling of bioactivation and detoxification of the alkenylbenzene methyleugenol in human as compared with rat Toxicology and Applied Pharmacology ·Ala’ Ali Ahmad Al-Subeihi, Bert Spenkelink, Ans Punt, Marelle G. Boersma, Peter J. van Bladeren, Ivonne M.C.M. Rietjens	2012	38
11	Physiologically based biokinetic model of bioactivation and detoxification of the alkenylbenzene methyleugenol in rat Toxicology in Vitro ·Ala’ Ali Ahmad Al-Subeihi, Bert Spenkelink, Novalia Rachmawati, Marelle G. Boersma, Ans Punt, Jacques Vervoort, Peter J. van Bladeren, Ivonne M.C.M. Rietjens	2010	35
12	Physiologically Based Kinetic Models for the Alkenylbenzene Elemicin in Rat and Human and Possible Implications for Risk Assessment Chemical Research in Toxicology ·Suzanne J. P. L. van den Berg, Ans Punt, Ans E. M. F. Soffers, Jacques Vervoort, Stephen Ngeleja, Bert Spenkelink, Ivonne M.C.M. Rietjens	2012	32
13	In vivo validation of DNA adduct formation by estragole in rats predicted by physiologically based biodynamic modelling Mutagenesis ·Alicia Paini, Ans Punt, Gabriele Scholz, Eric Gremaud, Bert Spenkelink, G.M. Alink, Benoı̂t Schilter, Peter J. van Bladeren, Ivonne M.C.M. Rietjens	2012	30
14	An n-3 PUFA-rich microalgal oil diet protects to a similar extent as a fish oil-rich diet against AOM-induced colonic aberrant crypt foci in F344 rats Food and Chemical Toxicology ·Vincent A. van Beelen, Bert Spenkelink, Hans Mooibroek, Lolke Sijtsma, Dirk Bosch, Ivonne M.C.M. Rietjens, G.M. Alink	2008	28
15	The use of biochemical parameters in comparative toxicological studies with the cormorant () in the Netherlands Chemosphere ·Martin van den Berg, Bart L.H.J. Craane, Theo L. Sinnige, Ineke J. Lutke-Schipholt, Bert Spenkelink, Abraham Brouwer	1992	23
16	Use of Physiologically Based Kinetic Modeling to Predict Rat Gut Microbial Metabolism of the Isoflavone Daidzein to S‐Equol and Its Consequences for ERα Activation Molecular Nutrition & Food Research ·Qianrui Wang, Bert Spenkelink, Rungnapa Boonpawa, Ivonne M.C.M. Rietjens, Karsten Beekmann	2020	22
17	Use of Physiologically Based Pharmacokinetic Modeling to Predict Human Gut Microbial Conversion of Daidzein to S-Equol Journal of Agricultural and Food Chemistry ·Qianrui Wang, Bert Spenkelink, Rungnapa Boonpawa, Ivonne M.C.M. Rietjens	2021	21
18	Differential toxicity as a result of apical and basolateral treatment of LLC-PK1 monolayers with S-(1,2,3,4,4-pentachlorobutadienyl)glutathione and N-acetyl-S-(1,2,3,4,4-pentachlorobutadienyl)-L-cysteine Chemico-Biological Interactions ·J.J.W.M. Mertens, John G. J. Weijnen, W. J. van Doorn, Bert Spenkelink, J.H.M. Temmink, Peter J. van Bladeren	1988	20
19	Relative embryotoxic potency of p-substituted phenols in the embryonic stem cell test (EST) and comparison to their toxic potency in vivo and in the whole embryo culture (WEC) assay Toxicology Letters ·Marije Strikwold, R.A. Woutersen, Bert Spenkelink, Ans Punt, Ivonne M.C.M. Rietjens	2012	18
20	Physiologically Based Kinetic Modeling-Facilitated Reverse Dosimetry to Predict In Vivo Red Blood Cell Acetylcholinesterase Inhibition Following Exposure to Chlorpyrifos in the Caucasian and Chinese Population Toxicological Sciences ·Shensheng Zhao, Lenny Kamelia, Rungnapa Boonpawa, Sebastiaan Wesseling, Bert Spenkelink, Ivonne M.C.M. Rietjens	2019	17

About Bert Spenkelink

Bert Spenkelink is a scholar working on Health, Toxicology and Mutagenesis, Cancer Research, Pharmacology, Molecular Biology and Oncology, having authored 36 papers that have together received 1.2k indexed citations. Recurring topics across this work include Carcinogens and Genotoxicity Assessment (10 papers), Pharmacogenetics and Drug Metabolism (7 papers), Effects and risks of endocrine disrupting chemicals (6 papers), Animal testing and alternatives (4 papers), Drug Transport and Resistance Mechanisms (4 papers), Environmental Toxicology and Ecotoxicology (4 papers), Toxic Organic Pollutants Impact (3 papers) and Phytoestrogen effects and research (3 papers). The work is most often cited by research in Biochemistry (158 citations), Health, Toxicology and Mutagenesis (320 citations), Pharmacology (103 citations), Cancer Research (167 citations) and Molecular Medicine (44 citations). Bert Spenkelink has collaborated with scholars based in Netherlands, Thailand and Switzerland. Frequent co-authors include Ivonne M.C.M. Rietjens, Ans Punt, Marelle G. Boersma, Laura de Haan, Nicole H.P. Cnubben, Jelmer J. van Zanden, G.M. Alink, Peter J. van Bladeren, Hester van der Woude and J.H. Koeman. Their work appears in journals such as Archives of Toxicology, Toxicology in Vitro, Chemico-Biological Interactions, Environmental Toxicology and Chemistry and Journal of Agricultural and Food Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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