Benoı̂t Gigant

6.5k citations

63 papers · 5.2k · 2 hit papers · h-index 32

Impact in

Cell Biology top 0.5%
- Microtubule and mitosis dynamics
Organic Chemistry top 1%
- Synthesis and biological activity
- Click Chemistry and Applications

Papers in

Molecular Biology 50
- 14-3-3 protein interactions 20
- Photosynthetic Processes and Mechanisms 15
- Ubiquitin and proteasome pathways 11
- Chemical Synthesis and Analysis 8
- Glycosylation and Glycoproteins Research 5
Cell Biology 39
- Microtubule and mitosis dynamics 39
- Cellular transport and secretion 13

Co-authors: M. Knossow (46 shared papers)Raimond B. G. Ravelli (6 shared papers)Patrick A. Curmi (8 shared papers)André Sobel (6 shared papers)Sylvie Lachkar (6 shared papers)Isabelle Jourdain (3 shared papers)Chunguang Wang (10 shared papers)Michel O. Steinmetz (2 shared papers)
Journals: Journal of Biological Chemistry (7 papers)Proceedings of the National Academy of Sciences (6 papers)Structure (3 papers)Nature (3 papers)Nature Communications (3 papers)
Partner nations: France China Switzerland

In The Last Decade

Benoı̂t Gigant

63 papers receiving 5.1k citations

Benoı̂t Gigant's Hit Papers

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Structural basis for the regulation of tubulin by vinblastine 2005 · 599 citations

Peers

Countries citing papers authored by Benoı̂t Gigant

Since Specialization

Citations

This map shows the geographic impact of Benoı̂t Gigant's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Benoı̂t Gigant with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Benoı̂t Gigant more than expected).

Fields of papers citing papers by Benoı̂t Gigant

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Benoı̂t Gigant. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Benoı̂t Gigant. The network helps show where Benoı̂t Gigant may publish in the future.

Co-authors

The 25 scholars most cited alongside Benoı̂t Gigant, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Benoı̂t Gigant Line = papers co-authored together Benoı̂t Gigant links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 63 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain Nature ·Raimond B. G. Ravelli, Benoı̂t Gigant, Patrick A. Curmi, Isabelle Jourdain, Sylvie Lachkar, André Sobel, M. Knossow Hit paper breakdown →	2004	1370
2	Structural basis for the regulation of tubulin by vinblastine Nature ·Benoı̂t Gigant, Chunguang Wang, Raimond B. G. Ravelli, Fanny Roussi, Michel O. Steinmetz, Patrick A. Curmi, André Sobel, M. Knossow Hit paper breakdown →	2005	599
3	Variations in the colchicine-binding domain provide insight into the structural switch of tubulin Proceedings of the National Academy of Sciences ·Audrey Dorléans, Benoı̂t Gigant, Raimond B. G. Ravelli, Patrick Mailliet, Vincent Mikol, M. Knossow	2009	218
4	The 4 Å X-Ray Structure of a Tubulin:Stathmin-like Domain Complex Cell ·Benoı̂t Gigant, Patrick A. Curmi, Carole Martin-Barbey, Elodie Charbaut, Sylvie Lachkar, Luc Lebeau, S. Siavoshian, André Sobel, M. Knossow	2000	212
5	Structure of influenza virus haemagglutinin complexed with a neutralizing antibody Nature ·Thierry Bizebard, Benoı̂t Gigant, Pascal Rigolet, Bjarne Rasmussen, Olivier Diat, Peter BÃ¶seckei, Steve A. Wharton, J.J. Skehel, M. Knossow	1995	200
6	Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery FEBS Journal ·Yuxi Wang, Hang Zhang, Benoı̂t Gigant, Yamei Yu, Yangping Wu, Xi Chen, Qinhuai Lai, Zhao-ya Yang, Qiang Chen, Jinliang Yang	2015	191
7	The β-Thymosin/WH2 Domain Cell ·Maud Hertzog, Carine van Heijenoort, Dominique Didry, Martin Gaudier, Jérôme Coûtant, Benoı̂t Gigant, Gérard Didelot, Thomas Préat, M. Knossow, Éric Guittet, Marie-France Carlier	2004	172
8	Structure of a kinesin–tubulin complex and implications for kinesin motility Nature Structural & Molecular Biology ·Benoı̂t Gigant, Weiyi Wang, Birgit Dreier, Qiyang Jiang, Ludovic Pecqueur, Andreas Plückthun, Chunguang Wang, M. Knossow	2013	131
9	The Determinants That Govern Microtubule Assembly from the Atomic Structure of GTP-Tubulin Journal of Molecular Biology ·Agata Nawrotek, M. Knossow, Benoı̂t Gigant	2011	126
10	Structural insight into the inhibition of tubulin by vinca domain peptide ligands EMBO Reports ·Anthony Cormier, Matthieu Marchand, Raimond B. G. Ravelli, M. Knossow, Benoı̂t Gigant	2008	126
11	An Antibody That Prevents the Hemagglutinin Low pH Fusogenic Transition Virology ·C. Barbey-Martin, Benoı̂t Gigant, Thierry Bizebard, Lesley J. Calder, Stephen A. Wharton, J.J. Skehel, M. Knossow	2002	124
12	Mechanism of Neutralization of Influenza Virus Infectivity by Antibodies Virology ·M. Knossow, Martin Gaudier, A. R. Douglas, B. Barrère, Thierry Bizebard, Catherine Barbey, Benoı̂t Gigant, J.J. Skehel	2002	120
13	A designed ankyrin repeat protein selected to bind to tubulin caps the microtubule plus end Proceedings of the National Academy of Sciences ·Ludovic Pecqueur, Christian Duellberg, Birgit Dreier, Qiyang Jiang, Chunguang Wang, Andreas Plückthun, Thomas Surrey, Benoı̂t Gigant, M. Knossow	2012	110
14	The structure of apo-kinesin bound to tubulin links the nucleotide cycle to movement Nature Communications ·Luyan Cao, Weiyi Wang, Qiyang Jiang, Chunguang Wang, M. Knossow, Benoı̂t Gigant	2014	105
15	The Mechanism of Tubulin Assembly into Microtubules: Insights from Structural Studies iScience ·M. Knossow, Valérie Campanacci, Liza Ammar Khodja, Benoı̂t Gigant	2020	76
16	Structural plasticity of tubulin assembly probed by vinca-domain ligands Acta Crystallographica Section D Biological Crystallography ·F.M. Ranaivoson, Benoı̂t Gigant, Simon Berritt, Madeleine M. Joullié, M. Knossow	2012	68
17	Structural Convergence in the Active Sites of a Family of Catalytic Antibodies Science ·Jean‐Baptiste Charbonnier, Béatrice Golinelli‐Pimpaneau, Benoı̂t Gigant, Dan S. Tawfik, Rachel Chap, Daniel G. Schindler, Seho Kim, Bernard Green, Zelig Eshhar, M. Knossow	1997	63
18	Mechanism of microtubule stabilization by taccalonolide AJ Nature Communications ·Yuxi Wang, Yamei Yu, Guo‐Bo Li, Shuang Li, Chengyong Wu, Benoı̂t Gigant, Wenming Qin, Hao Chen, Yangping Wu, Qiang Chen, Jinliang Yang	2017	61
19	Insight into microtubule disassembly by kinesin-13s from the structure of Kif2C bound to tubulin Nature Communications ·Weiyi Wang, Soraya Cantos-Fernandes, Yuncong Lv, Hureshitanmu Kuerban, Shoeb Ahmad, Chunguang Wang, Benoı̂t Gigant	2017	59
20	Microtubule-Destabilizing Agents: Structural and Mechanistic Insights from the Interaction of Colchicine and Vinblastine with Tubulin Topics in current chemistry ·Benoı̂t Gigant, Anthony Cormier, Audrey Dorléans, Raimond B. G. Ravelli, M. Knossow	2008	56

About Benoı̂t Gigant

Benoı̂t Gigant is a scholar working on Molecular Biology, Cell Biology, Radiology, Nuclear Medicine and Imaging, Epidemiology and Organic Chemistry, having authored 63 papers that have together received 5.2k indexed citations. Recurring topics across this work include Microtubule and mitosis dynamics (39 papers), 14-3-3 protein interactions (20 papers), Photosynthetic Processes and Mechanisms (15 papers), Monoclonal and Polyclonal Antibodies Research (14 papers), Cellular transport and secretion (13 papers), Ubiquitin and proteasome pathways (11 papers), Chemical Synthesis and Analysis (8 papers) and Glycosylation and Glycoproteins Research (5 papers). The work is most often cited by research in Cell Biology (2.0k citations), Organic Chemistry (1.5k citations), Molecular Biology (3.1k citations), Toxicology (123 citations) and Structural Biology (41 citations). Benoı̂t Gigant has collaborated with scholars based in France, China and Switzerland. Frequent co-authors include M. Knossow, Raimond B. G. Ravelli, Patrick A. Curmi, André Sobel, Sylvie Lachkar, Isabelle Jourdain, Chunguang Wang, Michel O. Steinmetz, Fanny Roussi and J.J. Skehel. Their work appears in journals such as Journal of Biological Chemistry, Proceedings of the National Academy of Sciences, Structure, Nature and Nature Communications.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Benoı̂t Gigant

Benoı̂t Gigant's Hit Papers

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