Ayako Moritomo

523 citations

26 papers · 394 · h-index 13

Impact in

Genetics
Organic Chemistry
- Synthesis and biological activity
- Synthesis and Biological Evaluation
- Click Chemistry and Applications

Papers in

Molecular Biology 15
- Microbial metabolism and enzyme function 5
- PI3K/AKT/mTOR signaling in cancer 3
Oncology 10
- Cytokine Signaling Pathways and Interactions 9

Co-authors: Takayuki Inoue (9 shared papers)Shohei Shirakami (6 shared papers)Hisao Hamaguchi (5 shared papers)Yutaka Nakajima (6 shared papers)Akira Nagashima (5 shared papers)Yasuyuki Higashi (5 shared papers)Masataka Morita (4 shared papers)Takashi Tojo (4 shared papers)
Journals: Bioorganic & Medicinal Chemistry (20 papers)Chemical and Pharmaceutical Bulletin (2 papers)Journal of Chemical Information and Modeling (1 paper)Drug Discovery Today (1 paper)Synthetic Communications (1 paper)
Partner nations: Japan Denmark

In The Last Decade

Ayako Moritomo

26 papers receiving 383 citations

Peers

Countries citing papers authored by Ayako Moritomo

Since Specialization

Citations

This map shows the geographic impact of Ayako Moritomo's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ayako Moritomo with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ayako Moritomo more than expected).

Fields of papers citing papers by Ayako Moritomo

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ayako Moritomo. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ayako Moritomo. The network helps show where Ayako Moritomo may publish in the future.

Co-authors

The 25 scholars most cited alongside Ayako Moritomo, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Ayako Moritomo Line = papers co-authored together Ayako Moritomo links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 26 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Discovery and structural characterization of peficitinib (ASP015K) as a novel and potent JAK inhibitor Bioorganic & Medicinal Chemistry ·Hisao Hamaguchi, Y. Amano, Ayako Moritomo, Shohei Shirakami, Yutaka Nakajima, Kazuo Nakai, Naoko Nomura, Misato Ito, Yasuyuki Higashi, Takayuki Inoue	2018	66
2	Novel 7H-pyrrolo[2,3-d]pyrimidine derivatives as potent and orally active STAT6 inhibitors Bioorganic & Medicinal Chemistry ·S. Nagashima, Takeshi Hondo, Hiroshi Nagata, Takashi Ogiyama, Jun Maeda, Hiroaki Hoshii, Toru Kontani, Sadao Kuromitsu, Keiko Ohga, Masaya Orita, Kazuki Ohno, Ayako Moritomo, Koichi Shiozuka, Masako Furutani, Makoto Takeuchi, Mitsuaki Ohta, Shin‐ichi Tsukamoto	2009	39
3	Novel 1H-imidazol-2-amine derivatives as potent and orally active vascular adhesion protein-1 (VAP-1) inhibitors for diabetic macular edema treatment Bioorganic & Medicinal Chemistry ·Takayuki Inoue, Masataka Morita, Takashi Tojo, Akira Nagashima, Ayako Moritomo, Hiroshi Miyake	2013	29
4	Small-World Phenomena in Chemical Library Networks: Application to Fragment-Based Drug Discovery Journal of Chemical Information and Modeling ·Naoki Tanaka, Kazuki Ohno, Tatsuya Niimi, Ayako Moritomo, Kenichi Mori, Masaya Orita	2009	24
5	Synthesis and evaluation of novel 1H-pyrrolo[2,3-b]pyridine-5-carboxamide derivatives as potent and orally efficacious immunomodulators targeting JAK3 Bioorganic & Medicinal Chemistry ·Yutaka Nakajima, Takayuki Inoue, Kazuo Nakai, Koichiro Mukoyoshi, Hisao Hamaguchi, Keiko Hatanaka, Hiroshi Sasaki, Akira Tanaka, Fumie Takahashi, Shigeki Kunikawa, Hiroyuki Usuda, Ayako Moritomo, Yasuyuki Higashi, Masamichi Inami, Shohei Shirakami	2015	20
6	Synthesis and SAR study of new thiazole derivatives as vascular adhesion protein-1 (VAP-1) inhibitors for the treatment of diabetic macular edema Bioorganic & Medicinal Chemistry ·Takayuki Inoue, Masataka Morita, Takashi Tojo, Kousei Yoshihara, Akira Nagashima, Ayako Moritomo, Mitsuru Ohkubo, Hiroshi Miyake	2012	19
7	Synthesis and structure–activity relationship of fused-pyrimidine derivatives as a series of novel GPR119 agonists Bioorganic & Medicinal Chemistry ·Kenji Negoro, Yasuhiro Yonetoku, Ayako Moritomo, Masahiko Hayakawa, Kazuhiko Iikubo, S. Yoshida, Makoto Takeuchi, Mitsuaki Ohta	2012	19
8	Discovery of 3,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2(1H)-one derivatives as novel JAK inhibitors Bioorganic & Medicinal Chemistry ·Hiroaki Yamagishi, Shohei Shirakami, Yutaka Nakajima, Akira Tanaka, Fumie Takahashi, Hisao Hamaguchi, Keiko Hatanaka, Ayako Moritomo, Masamichi Inami, Yasuyuki Higashi, Takayuki Inoue	2015	17
9	Synthesis and Evaluation of 1<i>H</i>-Pyrrolo[2,3-<i>b</i>]pyridine Derivatives as Novel Immunomodulators Targeting Janus Kinase 3 Chemical and Pharmaceutical Bulletin ·Yutaka Nakajima, Takashi Tojo, Masataka Morita, Keiko Hatanaka, Shohei Shirakami, Akira Tanaka, Hiroshi Sasaki, Kazuo Nakai, Koichiro Mukoyoshi, Hisao Hamaguchi, Fumie Takahashi, Ayako Moritomo, Yasuyuki Higashi, Takayuki Inoue	2015	16
10	Discovery and biological evaluation of novel pyrazolopyridine derivatives as potent and orally available PI3Kδ inhibitors Bioorganic & Medicinal Chemistry ·Toshihiro Hamajima, Fumie Takahashi, Koji Kato, Koichiro Mukoyoshi, Kousei Yoshihara, Susumu Yamaki, Yukihito Sugano, Ayako Moritomo, Kaoru Yamagami, Koji Yokoo, Hidehiko Fukahori	2018	15
11	Synthesis and SAR study of new thiazole derivatives as vascular adhesion protein-1 (VAP-1) inhibitors for the treatment of diabetic macular edema: Part 2 Bioorganic & Medicinal Chemistry ·Takayuki Inoue, Masataka Morita, Takashi Tojo, Akira Nagashima, Ayako Moritomo, Keisuke Imai, Hiroshi Miyake	2013	14
12	Analysis of fluoroquinolone-resistance using MIC determination and homology modelling of ParC of contemporary Mycoplasma genitalium strains Journal of Infection and Chemotherapy ·Ryoichi Hamasuna, Hiroyuki Hanzawa, Ayako Moritomo, Masahiro Matsumoto, Hisami Aono, Ikko Tomisaki, Takaaki Akasaka, Naohiro Fujimoto, Jørgen Skov Jensen	2021	14
13	Synthesis and structure–activity relationships of new carbonyl guanidine derivatives as novel dual 5-HT2B and 5-HT7 receptor antagonists Bioorganic & Medicinal Chemistry ·Ayako Moritomo, Hiroyoshi Yamada, Toshihiro Watanabe, Hirotsune Itahana, Shinobu Akuzawa, Minoru Okada, Mitsuaki Ohta	2013	12
14	Synthesis and structure–activity relationships of new carbonyl guanidine derivatives as novel dual 5-HT2B and 5-HT7 receptor antagonists. Part 2 Bioorganic & Medicinal Chemistry ·Ayako Moritomo, Hiroyoshi Yamada, Toshihiro Watanabe, Hirotsune Itahana, Yuji Koga, Shinobu Akuzawa, Minoru Okada	2014	12
15	Synthesis and structure activity relationships of glycine amide derivatives as novel Vascular Adhesion Protein-1 inhibitors Bioorganic & Medicinal Chemistry ·Susumu Yamaki, Daisuke Suzuki, Jiro Fujiyasu, Masahiro Neya, Akira Nagashima, Mitsuhiro Kondo, Takafumi Akabane, Keitaro Kadono, Ayako Moritomo, Kosei Yoshihara	2016	11
16	Novel quinuclidinyl heteroarylcarbamate derivatives as muscarinic receptor antagonists Bioorganic & Medicinal Chemistry ·S. Nagashima, Yuji Matsushima, Hisao Hamaguchi, Hiroshi Nagata, Toru Kontani, Ayako Moritomo, Tadatsura Koshika, Makoto Takeuchi	2014	11
17	Regioselective Alkylation of Thiazolylsulfonamides: Direct and Efficient Synthesis of 3‐Alkylthiazolidene Derivatives Synthetic Communications ·Naoyuki Masuda, Osamu Yamamoto, Masahiro Fujii, Tetsuro Ohgami, Ayako Moritomo, Toru Kontani, Shunji Kageyama, Mitsuaki Ohta	2005	8
18	Synthesis and pharmacological evaluation of glycine amide derivatives as novel vascular adhesion protein-1 inhibitors without CYP3A4 and CYP2C19 inhibition Bioorganic & Medicinal Chemistry ·Susumu Yamaki, Yuji Koga, Akira Nagashima, Mitsuhiro Kondo, Yoshiaki Shimada, Keitaro Kadono, Ayako Moritomo, Kosei Yoshihara	2017	7
19	Synthesis and structure–activity relationships of pyrazine-2-carboxamide derivatives as novel echinoderm microtubule-associated protein-like 4 (EML4)–anaplastic lymphoma kinase (ALK) inhibitors Bioorganic & Medicinal Chemistry ·Kazuhiko Iikubo, Kazuo KUROSAWA, Takahiro Matsuya, Yutaka Kondoh, Akio Kamikawa, Ayako Moritomo, Yoshinori Iwai, Hiroshi Tomiyama, Itsuro Shimada	2019	7
20	Design, synthesis, and evaluation of 4,6-diaminonicotinamide derivatives as novel and potent immunomodulators targeting JAK3 Bioorganic & Medicinal Chemistry ·Yutaka Nakajima, Naohiro Aoyama, Fumie Takahashi, Hiroshi Sasaki, Keiko Hatanaka, Ayako Moritomo, Masamichi Inami, Misato Ito, Koji Nakamura, Fumihiro Nakamori, Takayuki Inoue, Shohei Shirakami	2016	7

About Ayako Moritomo

Ayako Moritomo is a scholar working on Molecular Biology, Oncology, Pharmacology, Organic Chemistry and Genetics, having authored 26 papers that have together received 394 indexed citations. Recurring topics across this work include Cytokine Signaling Pathways and Interactions (9 papers), Microbial metabolism and enzyme function (5 papers), Pharmacological Effects of Natural Compounds (5 papers), Quinazolinone synthesis and applications (3 papers), Chronic Lymphocytic Leukemia Research (3 papers), Coagulation, Bradykinin, Polyphosphates, and Angioedema (3 papers), Biochemical Acid Research Studies (3 papers) and PI3K/AKT/mTOR signaling in cancer (3 papers). The work is most often cited by research in Genetics (55 citations), Organic Chemistry (140 citations), Biochemistry (27 citations), Computational Theory and Mathematics (55 citations) and Oncology (82 citations). Ayako Moritomo has collaborated with scholars based in Japan and Denmark. Frequent co-authors include Takayuki Inoue, Shohei Shirakami, Hisao Hamaguchi, Yutaka Nakajima, Akira Nagashima, Yasuyuki Higashi, Masataka Morita, Takashi Tojo, Kazuo Nakai and Misato Ito. Their work appears in journals such as Bioorganic & Medicinal Chemistry, Chemical and Pharmaceutical Bulletin, Journal of Chemical Information and Modeling, Drug Discovery Today and Synthetic Communications.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Ayako Moritomo

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Ayako Moritomo

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About Ayako Moritomo

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