Arnim Pause

20.4k citations

89 papers · 16.6k · 4 hit papers · h-index 52

Impact in

Cancer Research top 0.5%
- Cancer, Hypoxia, and Metabolism
Molecular Biology top 0.5%
- RNA and protein synthesis mechanisms
- RNA Research and Splicing
- PI3K/AKT/mTOR signaling in cancer
- RNA modifications and cancer
- Ubiquitin and proteasome pathways

Papers in

Cancer Research 21
- Cancer, Hypoxia, and Metabolism 18
Molecular Biology 63
- RNA and protein synthesis mechanisms 20
- RNA Research and Splicing 16
- RNA modifications and cancer 11
- Metabolism, Diabetes, and Cancer 10

Co-authors: Nahum Sonenberg (22 shared papers)Graham J. Belsham (4 shared papers)Richard D. Klausner (11 shared papers)Anne‐Claude Gingras (5 shared papers)Tai-An Lin (2 shared papers)John C. Lawrence (2 shared papers)Nathalie Méthot (4 shared papers)Yuri V. Svitkin (5 shared papers)
Journals: Proceedings of the National Academy of Sciences (9 papers)Molecular and Cellular Biology (7 papers)Journal of Biological Chemistry (5 papers)Cell Reports (4 papers)The EMBO Journal (4 papers)
Partner nations: Canada United States United Kingdom

In The Last Decade

Arnim Pause

89 papers receiving 16.2k citations

Arnim Pause's Hit Papers

align trajectories log scale

AMPK Maintains Cellular Metabolic Homeostasis through Regulation of Mitochondrial Reactive Oxygen Species 2017 · 459 citations

What are hit papers?

Paper score: A paper's citations measured against the top-1% bar of its own field and year: the square root of citations ÷ bar, so 1 means right at the bar and 2 means four times its citations. The bar blends the citation counts that enter the top 1% of the paper's subfields in its year (weighted 89.5%), of those subfields over all years (0.5%) and of its year across all fields (10%); a subfield and year with fewer than 400 papers takes its year's bar. Papers from 2026 are not scored yet: in an unfinished year, when a paper appeared matters more than how it is cited.

Hit paper: A paper cited at least 1.5× the top-1% bar of its field and year: a paper score of at least √1.5.

2017 Cell Reports
2016 Autophagy
2013 Cell Metabolism
1994 Nature

Peers

Countries citing papers authored by Arnim Pause

Since Specialization

Citations

This map shows the geographic impact of Arnim Pause's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Arnim Pause with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Arnim Pause more than expected).

Fields of papers citing papers by Arnim Pause

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Arnim Pause. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Arnim Pause. The network helps show where Arnim Pause may publish in the future.

Co-authors

The 25 scholars most cited alongside Arnim Pause, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Arnim Pause Line = papers co-authored together Arnim Pause links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 89 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) Autophagy ·Daniel J. Klionsky, Kotb Abdelmohsen, Akihisa Abe, Md. Joynal Abedin, Hagai Abeliovich, Abraham Acevedo‐Arozena, Hiroaki Adachi, Christopher M. Adams Hit paper breakdown →	2016	4660
2	Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function Nature ·Arnim Pause, Graham J. Belsham, Anne‐Claude Gingras, Olivier Donzé, Tai-An Lin, John C. Lawrence, Nahum Sonenberg Hit paper breakdown →	1994	1077
3	mTORC1 Controls Mitochondrial Activity and Biogenesis through 4E-BP-Dependent Translational Regulation Cell Metabolism ·Masahiro Morita, Simon‐Pierre Gravel, Valérie Chénard, Kristina Sikström, Liang Zheng, Tommy Alain, Valentina Gandin, Daina Zofija Avizonis Hit paper breakdown →	2013	676
4	PHAS-I as a Link Between Mitogen-Activated Protein Kinase and Translation Initiation Science ·Tai-An Lin, Xianming Kong, Timothy Haystead, Arnim Pause, Graham J. Belsham, Nahum Sonenberg, John C. Lawrence	1994	608
5	The Translation Initiation Factor eIF-4E Binds to a Common Motif Shared by the Translation Factor eIF-4γ and the Translational Repressors 4E-Binding Proteins Molecular and Cellular Biology ·Sylvie Mader, Han B. Lee, Arnim Pause, Nahum Sonenberg	1995	581
6	Mutational analysis of a DEAD box RNA helicase: the mammalian translation initiation factor eIF‐4A. The EMBO Journal ·Arnim Pause, Nahum Sonenberg	1992	534
7	Repression of cap‐dependent translation by 4E‐binding protein 1: competition with p220 for binding to eukaryotic initiation factor‐4E. The EMBO Journal ·Ashkan Haghighat, Sylvie C Mader, Arnim Pause, Nahum Sonenberg	1995	520
8	Inhibition of Transcription Elongation by the VHL Tumor Suppressor Protein Science ·Delin Duan, Arnim Pause, Wilson H. Burgess, Teijiro Aso, David Y.T. Chen, Karla Pfeil Garrett, Ronald C. Conaway, Joan Weliky Conaway	1995	495
9	AMPK Maintains Cellular Metabolic Homeostasis through Regulation of Mitochondrial Reactive Oxygen Species Cell Reports ·Rebecca C. Rabinovitch, Bożena Samborska, Brandon Faubert, Eric H. Ma, Simon‐Pierre Gravel, Sylvia Andrzejewski, Thomas C. Raissi, Arnim Pause Hit paper breakdown →	2017	459
10	Identification of the von Hippel–Lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex Proceedings of the National Academy of Sciences ·Kazuhiro Iwaï, Koji Yamanaka, Takumi Kamura, Nagahiro Minato, Ronald C. Conaway, Joan Weliky Conaway, Richard D. Klausner, Arnim Pause	1999	428
11	The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins Proceedings of the National Academy of Sciences ·Arnim Pause, Stephen Lee, Robert Worrell, David Y.T. Chen, Wilson H. Burgess, William Marston Linehan, Richard D. Klausner	1997	422
12	The requirement for eukaryotic initiation factor 4A (eIF4A) in translation is in direct proportion to the degree of mRNA 5′ secondary structure RNA ·Yuri V. Svitkin, Arnim Pause, Ashkan Haghighat, Stéphane Pyronnet, Gary W. Witherell, Graham J. Belsham, Nahum Sonenberg	2001	388
13	Dominant negative mutants of mammalian translation initiation factor eIF‐4A define a critical role for eIF‐4F in cap‐dependent and cap‐independent initiation of translation. The EMBO Journal ·Arnim Pause, Nathalie Méthot, Yuri V. Svitkin, William C. Merrick, Nahum Sonenberg	1994	343
14	An oxygen-regulated switch in the protein synthesis machinery Nature ·James Uniacke, Chet E. Holterman, Gabriel Lachance, Aleksandra Franovic, Mathieu D. Jacob, Marc Robert Fabian, Josianne Payette, Martin Holčı́k	2012	264
15	The HRIGRXXR region of the DEAD box RNA helicase eukaryotic translation initiation factor 4A is required for RNA binding and ATP hydrolysis. Molecular and Cellular Biology ·Arnim Pause, Nathalie Méthot, Nahum Sonenberg	1993	260
16	mTOR Pathways in Cancer and Autophagy Cancers ·Mathieu Paquette, Leeanna El–Houjeiri, Arnim Pause	2018	260
17	Mitochondrial Phosphoenolpyruvate Carboxykinase Regulates Metabolic Adaptation and Enables Glucose-Independent Tumor Growth Molecular Cell ·Emma E. Vincent, Alexey Sergushichev, Takla Griss, Marie‐Claude Gingras, Bożena Samborska, Thierry Ntimbane, Paula Pinto Coelho, Julianna Blagih	2015	233
18	The von Hippel–Lindau tumor suppressor gene is required for cell cycle exit upon serum withdrawal Proceedings of the National Academy of Sciences ·Arnim Pause, Stephen Lee, Kim M. Lonergan, Richard D. Klausner	1998	212
19	Activation of the translational suppressor 4E-BP1 following infection with encephalomyocarditis virus and poliovirus. Proceedings of the National Academy of Sciences ·Anne‐Claude Gingras, Yuri V. Svitkin, Graham J. Belsham, Arnim Pause, Nahum Sonenberg	1996	196
20	The eIF4E-binding proteins 1 and 2 are negative regulators of cell growth. PubMed ·Anne‐Claude Gingras, Arnim Pause, Nahum Sonenberg +1 other	1996	186

About Arnim Pause

Arnim Pause is a scholar working on Cancer Research, Molecular Biology, Cell Biology, Hepatology and Epidemiology, having authored 89 papers that have together received 16.6k indexed citations. Recurring topics across this work include RNA and protein synthesis mechanisms (20 papers), Cancer, Hypoxia, and Metabolism (18 papers), RNA Research and Splicing (16 papers), RNA modifications and cancer (11 papers), Metabolism, Diabetes, and Cancer (10 papers), Hepatitis C virus research (10 papers), Autophagy in Disease and Therapy (9 papers) and Renal cell carcinoma treatment (9 papers). The work is most often cited by research in Cancer Research (2.5k citations), Molecular Biology (10.6k citations), Aging (259 citations), Epidemiology (4.2k citations) and Physiology (532 citations). Arnim Pause has collaborated with scholars based in Canada, United States and United Kingdom. Frequent co-authors include Nahum Sonenberg, Graham J. Belsham, Richard D. Klausner, Anne‐Claude Gingras, Tai-An Lin, John C. Lawrence, Nathalie Méthot, Yuri V. Svitkin, Ashkan Haghighat and Stephen Lee. Their work appears in journals such as Proceedings of the National Academy of Sciences, Molecular and Cellular Biology, Journal of Biological Chemistry, Cell Reports and The EMBO Journal.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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