A. van Caam

1.9k citations

45 papers · 1.4k · h-index 18

Impact in

Rheumatology top 1%
- Osteoarthritis Treatment and Mechanisms
Cancer Research top 10%
- MicroRNA in disease regulation

Papers in

Rheumatology 29
- Osteoarthritis Treatment and Mechanisms 27
Molecular Biology 23
- TGF-β signaling in diseases 16
- Bone Metabolism and Diseases 5

Co-authors: P.M. van der Kraan (29 shared papers)Eva Thijssen (4 shared papers)E.N. Blaney Davidson (12 shared papers)Marije I. Koenders (17 shared papers)Wojciech Madej (6 shared papers)Peter L. E. M. van Lent (8 shared papers)Fons A. J. van de Loo (9 shared papers)Wim B. van den Berg (4 shared papers)
Journals: Osteoarthritis and Cartilage (16 papers)Annals of the Rheumatic Diseases (6 papers)Lara D. Veeken (3 papers)International Journal of Molecular Sciences (2 papers)Cells (2 papers)
Partner nations: Netherlands United States Switzerland

In The Last Decade

A. van Caam

43 papers receiving 1.4k citations

Peers

Countries citing papers authored by A. van Caam

Since Specialization

Citations

This map shows the geographic impact of A. van Caam's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by A. van Caam with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites A. van Caam more than expected).

Fields of papers citing papers by A. van Caam

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by A. van Caam. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by A. van Caam. The network helps show where A. van Caam may publish in the future.

Co-authors

The 25 scholars most cited alongside A. van Caam, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with A. van Caam Line = papers co-authored together A. van Caam links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 45 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Obesity and osteoarthritis, more than just wear and tear: pivotal roles for inflamed adipose tissue and dyslipidaemia in obesity-induced osteoarthritis Lara D. Veeken ·Eva Thijssen, A. van Caam, P.M. van der Kraan	2014	269
2	TGFβ/BMP Signaling Pathway in Cartilage Homeostasis Cells ·Nathalie G. M. Thielen, P.M. van der Kraan, A. van Caam	2019	184
3	Commercial Cow Milk Contains Physically Stable Extracellular Vesicles Expressing Immunoregulatory TGF-β PLoS ONE ·Bartijn C. H. Pieters, Onno J. Arntz, Miranda B. Bennink, Mathijs G A Broeren, A. van Caam, Marije I. Koenders, Peter L. E. M. van Lent, Wim B. van den Berg, Marieke de Vries, P.M. van der Kraan, Fons A. J. van de Loo	2015	178
4	Unraveling SSc Pathophysiology; The Myofibroblast Frontiers in Immunology ·A. van Caam, Madelon C Vonk, F.H.J. van den Hoogen, Peter van Lent, P.M. van der Kraan	2018	115
5	TGF-β is a potent inducer of Nerve Growth Factor in articular cartilage via the ALK5-Smad2/3 pathway. Potential role in OA related pain? Osteoarthritis and Cartilage ·E.N. Blaney Davidson, A. van Caam, E.L. Vitters, M.B. Bennink, Eva Thijssen, Wim B. van den Berg, Marije I. Koenders, Peter L. E. M. van Lent, Fons A. J. van de Loo, P.M. van der Kraan	2014	65
6	Reduced Euchromatin histone methyltransferase 1 causes developmental delay, hypotonia, and cranial abnormalities associated with increased bone gene expression in Kleefstra syndrome mice Developmental Biology ·Monique C.M. Balemans, Muhammad Ansar, Astrid Oudakker, A. van Caam, Brenda Bakker, E.L. Vitters, P.M. van der Kraan, Diederik R.H. de Bruijn, Sanne Janssen, Arthur J. Kuipers, Manon M. H. Huibers, Eliza M. Maliepaard, X. Frank Walboomers, Marco Benevento, Nael Nadif Kasri, Tjitske Kleefstra, Huiqing Zhou, Catharina E.E.M. Van der Zee, Hans van Bokhoven	2013	55
7	Physiological and excessive mechanical compression of articular cartilage activates Smad2/3P signaling Osteoarthritis and Cartilage ·Wojciech Madej, A. van Caam, E.N. Blaney Davidson, P.M. van der Kraan, Pieter Buma	2014	51
8	TGFβ1-induced SMAD2/3 and SMAD1/5 phosphorylation are both ALK5-kinase-dependent in primary chondrocytes and mediated by TAK1 kinase activity Arthritis Research & Therapy ·A. van Caam, Wojciech Madej, Amaya García de Vinuesa, Marie‐José Goumans, Peter ten Dijke, Esmeralda Blaney Davidson, Peter van der Kraan	2017	50
9	Ageing is associated with reduction of mechanically-induced activation of Smad2/3P signaling in articular cartilage Osteoarthritis and Cartilage ·Wojciech Madej, A. van Caam, E.N. Blaney Davidson, Gerjon Hannink, Pieter Buma, P.M. van der Kraan	2015	43
10	Inducible chondrocyte-specific overexpression of BMP2 in young mice results in severe aggravation of osteophyte formation in experimental OA without altering cartilage damage Annals of the Rheumatic Diseases ·E.N. Blaney Davidson, E.L. Vitters, M.B. Bennink, Peter L. E. M. van Lent, A. van Caam, Arjen B. Blom, Wim B. van den Berg, Fons A. J. van de Loo, P.M. van der Kraan	2014	42
11	Osteoarthritis year in review 2016: biology Osteoarthritis and Cartilage ·E.N. Blaney Davidson, A. van Caam, P.M. van der Kraan	2017	42
12	Expression of TGFβ-family signalling components in ageing cartilage: age-related loss of TGFβ and BMP receptors Osteoarthritis and Cartilage ·A. van Caam, Wojciech Madej, Eva Thijssen, Amaya García de Vinuesa, WB van den Berg, Marie‐José Goumans, Peter ten Dijke, E. Blaney Davidson, P.M. van der Kraan	2016	35
13	Unloading results in rapid loss of TGFβ signaling in articular cartilage: role of loading-induced TGFβ signaling in maintenance of articular chondrocyte phenotype? Osteoarthritis and Cartilage ·Wojciech Madej, A. van Caam, E. Blaney Davidson, Pieter Buma, P.M. van der Kraan	2016	31
14	The high affinity ALK1-ligand BMP9 induces a hypertrophy-like state in chondrocytes that is antagonized by TGFβ1 Osteoarthritis and Cartilage ·A. van Caam, E. Blaney Davidson, Amaya García de Vinuesa, E. van Geffen, WB van den Berg, Marie‐José Goumans, Peter ten Dijke, P. van der Kraan	2015	29
15	Transcription Factors in Cartilage Homeostasis and Osteoarthritis Biology ·M. Neefjes, A. van Caam, P.M. van der Kraan	2020	23
16	Osteoarthritis-Related Inflammation Blocks TGF-β’s Protective Effect on Chondrocyte Hypertrophy via (de)Phosphorylation of the SMAD2/3 Linker Region International Journal of Molecular Sciences ·Nathalie G. M. Thielen, M. Neefjes, Renske Wiegertjes, Guus van den Akker, E.L. Vitters, H. van Beuningen, Esmeralda Blaney Davidson, Marije I. Koenders, Peter van Lent, F. van de Loo, A. van Caam, Peter van der Kraan	2021	20
17	TGFβ-mediated expression of TGFβ-activating integrins in SSc monocytes: disturbed activation of latent TGFβ? Arthritis Research & Therapy ·A. van Caam, Joyce Aarts, Thomas van Ee, E.L. Vitters, Marije I. Koenders, F. van de Loo, P. van Lent, F. van den Hoogen, RM Thurlings, Madelon C Vonk, P.M. van der Kraan	2020	18
18	Therapeutic Options for Systemic Sclerosis: Current and Future Perspectives in Tackling Immune-Mediated Fibrosis Biomedicines ·Theodoros Ioannis Papadimitriou, A. van Caam, P.M. van der Kraan, Rogier M. Thurlings	2022	18
19	IL-37 diminishes proteoglycan loss in human OA cartilage: donor-specific link between IL-37 and MMP-3 Osteoarthritis and Cartilage ·E.W. van Geffen, A. van Caam, Wim Schreurs, F.A. van de Loo, Peter L. E. M. van Lent, Marije I. Koenders, Christian S. Thudium, Anne‐Christine Bay‐Jensen, E.N. Blaney Davidson, P.M. van der Kraan	2018	16
20	Expression of TGF-β Signaling Regulator RBPMS (RNA-Binding Protein With Multiple Splicing) Is Regulated by IL-1β and TGF-β Superfamily Members, and Decreased in Aged and Osteoarthritic Cartilage Cartilage ·S. Shanmugaapriya, A. van Caam, L. de Kroon, E.L. Vitters, Birgitte Walgreen, H. van Beuningen, E. Blaney Davidson, P.M. van der Kraan	2016	15

About A. van Caam

A. van Caam is a scholar working on Rheumatology, Molecular Biology, Pharmacology, Pathology and Forensic Medicine and Oncology, having authored 45 papers that have together received 1.4k indexed citations. Recurring topics across this work include Osteoarthritis Treatment and Mechanisms (27 papers), TGF-β signaling in diseases (16 papers), Inflammatory mediators and NSAID effects (9 papers), Systemic Sclerosis and Related Diseases (6 papers), Cell Adhesion Molecules Research (6 papers), Cancer-related molecular mechanisms research (6 papers), Cytokine Signaling Pathways and Interactions (5 papers) and Bone Metabolism and Diseases (5 papers). The work is most often cited by research in Rheumatology (687 citations), Cancer Research (237 citations), Immunology and Allergy (91 citations), Pharmacology (206 citations) and Urology (73 citations). A. van Caam has collaborated with scholars based in Netherlands, United States and Switzerland. Frequent co-authors include P.M. van der Kraan, Eva Thijssen, E.N. Blaney Davidson, Marije I. Koenders, Wojciech Madej, Peter L. E. M. van Lent, Fons A. J. van de Loo, Wim B. van den Berg, E.L. Vitters and Madelon C Vonk. Their work appears in journals such as Osteoarthritis and Cartilage, Annals of the Rheumatic Diseases, Lara D. Veeken, International Journal of Molecular Sciences and Cells.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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