Zhanjun Hou

2.5k citations

80 papers · 2.0k · h-index 27

Impact in

Rheumatology top 0.5%
- Folate and B Vitamins Research
Infectious Diseases top 5%
- HIV/AIDS drug development and treatment

Papers in

Rheumatology 52
- Folate and B Vitamins Research 52
Molecular Biology 51
- Biochemical and Molecular Research 33
- RNA modifications and cancer 11

Co-authors: Larry H. Matherly (72 shared papers)Aleem Gangjee (49 shared papers)Yijun Deng (5 shared papers)Sita Kugel Desmoulin (10 shared papers)Christina Cherian (18 shared papers)Mike R. Wilson (10 shared papers)Bharati Mitra (3 shared papers)Lisa Polin (16 shared papers)
Journals: Journal of Medicinal Chemistry (14 papers)Cancer Research (12 papers)Journal of Biological Chemistry (8 papers)Molecular Pharmacology (7 papers)Biochemical Journal (4 papers)
Partner nations: United States China Italy

In The Last Decade

Zhanjun Hou

75 papers receiving 1.9k citations

Peers

Countries citing papers authored by Zhanjun Hou

Since Specialization

Citations

This map shows the geographic impact of Zhanjun Hou's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Zhanjun Hou with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Zhanjun Hou more than expected).

Fields of papers citing papers by Zhanjun Hou

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Zhanjun Hou. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Zhanjun Hou. The network helps show where Zhanjun Hou may publish in the future.

Co-authors

The 25 scholars most cited alongside Zhanjun Hou, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Zhanjun Hou Line = papers co-authored together Zhanjun Hou links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 80 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Human reduced folate carrier: translation of basic biology to cancer etiology and therapy Cancer and Metastasis Reviews ·Larry H. Matherly, Zhanjun Hou, Yijun Deng	2007	215
2	The human proton-coupled folate transporter Cancer Biology & Therapy ·Sita Kugel Desmoulin, Zhanjun Hou, Aleem Gangjee, Larry H. Matherly	2012	126
3	Biology of the Major Facilitative Folate Transporters SLC19A1 and SLC46A1 Current topics in membranes ·Zhanjun Hou, Larry H. Matherly	2014	109
4	Synthesis and Biological Activity of a Novel Series of 6-Substituted Thieno[2,3-d]pyrimidine Antifolate Inhibitors of Purine Biosynthesis with Selectivity for High Affinity Folate Receptors over the Reduced Folate Carrier and Proton-Coupled Folate Transporter for Cellular Entry^† Journal of Medicinal Chemistry ·Yijun Deng, Xilin Zhou, Sita Kugel Desmoulin, Jianmei Wu, Christina Cherian, Zhanjun Hou, Larry H. Matherly, Aleem Gangjee	2009	68
5	Synthesis and Discovery of High Affinity Folate Receptor-Specific Glycinamide Ribonucleotide Formyltransferase Inhibitors with Antitumor Activity Journal of Medicinal Chemistry ·Yijun Deng, Yiqiang Wang, Christina Cherian, Zhanjun Hou, Steven Buck, Larry H. Matherly, Aleem Gangjee	2008	68
6	The Major Facilitative Folate Transporters Solute Carrier 19A1 and Solute Carrier 46A1: Biology and Role in Antifolate Chemotherapy of Cancer Drug Metabolism and Disposition ·Larry H. Matherly, Mike R. Wilson, Zhanjun Hou	2014	67
7	Chapter 5 Structure and Function of the Reduced Folate Carrier Vitamins and hormones ·Larry H. Matherly, Zhanjun Hou	2008	66
8	Synthesis, Biological, and Antitumor Activity of a Highly Potent 6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Antifolate Inhibitor with Proton-Coupled Folate Transporter and Folate Receptor Selectivity over the Reduced Folate Carrier That Inhibits β-Glycinamide Ribonucleotide Formyltransferase Journal of Medicinal Chemistry ·Lei Wang, Sita Kugel Desmoulin, Christina Cherian, Lisa Polin, Kathryn White, Juiwanna Kushner, Andreas Fulterer, Min‐Hwang Chang, Shermaine Mitchell-Ryan, Mark Stout, Michael F. Romero, Zhanjun Hou, Larry H. Matherly, Aleem Gangjee	2011	62
9	Therapeutic Targeting of a Novel 6-Substituted Pyrrolo [2,3-d]pyrimidine Thienoyl Antifolate to Human Solid Tumors Based on Selective Uptake by the Proton-Coupled Folate Transporter Molecular Pharmacology ·Sita Kugel Desmoulin, Lei Wang, Eric C. Hales, Lisa Polin, Kathryn White, Juiwanna Kushner, Mark Stout, Zhanjun Hou, Christina Cherian, Aleem Gangjee, Larry H. Matherly	2011	57
10	Therapeutic Targeting of Mitochondrial One-Carbon Metabolism in Cancer Molecular Cancer Therapeutics ·Aamod S. Dekhne, Zhanjun Hou, Aleem Gangjee, Larry H. Matherly	2020	55
11	Synthesis and Antitumor Activity of a Novel Series of 6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Antifolate Inhibitors of Purine Biosynthesis with Selectivity for High Affinity Folate Receptors and the Proton-Coupled Folate Transporter over the Reduced Folate Carrier for Cellular Entry Journal of Medicinal Chemistry ·Lei Wang, Christina Cherian, Sita Kugel Desmoulin, Lisa Polin, Yijun Deng, Jianmei Wu, Zhanjun Hou, Kathryn White, Juiwanna Kushner, Larry H. Matherly, Aleem Gangjee	2010	54
12	Targeting the Proton-Coupled Folate Transporter for Selective Delivery of 6-Substituted Pyrrolo[2,3-d]Pyrimidine Antifolate Inhibitors of De Novo Purine Biosynthesis in the Chemotherapy of Solid Tumors Molecular Pharmacology ·Sita Kugel Desmoulin, Yiqiang Wang, Jianmei Wu, Mark Stout, Zhanjun Hou, Andreas Fulterer, Min‐Hwang Chang, Michael F. Romero, Christina Cherian, Aleem Gangjee, Larry H. Matherly	2010	51
13	Functional Analysis of Chimeric Proteins of the Wilson Cu(I)-ATPase (ATP7B) and ZntA, a Pb(II)/Zn(II)/Cd(II)-ATPase fromEscherichia coli Journal of Biological Chemistry ·Zhanjun Hou, Suree Narindrasorasak, Bharat Bhushan, Bibudhendra Sarkar, Bharati Mitra	2001	42
14	Conserved Aspartic Acid 714 in Transmembrane Segment 8 of the ZntA Subgroup of P_1B-Type ATPases Is a Metal-Binding Residue Biochemistry ·S. Dutta, Junbo Liu, Zhanjun Hou, Bharati Mitra	2006	41
15	Synthesis and Biological Activity of 6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Regioisomers as Inhibitors of de Novo Purine Biosynthesis with Selectivity for Cellular Uptake by High Affinity Folate Receptors and the Proton-Coupled Folate Transporter over the Reduced Folate Carrier Journal of Medicinal Chemistry ·Lei Wang, Christina Cherian, Sita Kugel Desmoulin, Shermaine Mitchell-Ryan, Zhanjun Hou, Larry H. Matherly, Aleem Gangjee	2012	41
16	The Metal Specificity and Selectivity of ZntA from Escherichia coli Using the Acylphosphate Intermediate Journal of Biological Chemistry ·Zhanjun Hou, Bharati Mitra	2003	41
17	The promise and challenges of exploiting the proton-coupled folate transporter for selective therapeutic targeting of cancer Cancer Chemotherapy and Pharmacology ·Larry H. Matherly, Zhanjun Hou, Aleem Gangjee	2017	39
18	Dual Targeting of Epithelial Ovarian Cancer Via Folate Receptor α and the Proton-Coupled Folate Transporter with 6-Substituted Pyrrolo[2,3- d ]pyrimidine Antifolates Molecular Cancer Therapeutics ·Zhanjun Hou, Leda Gattoc, Carrie O’Connor, Yang Si, Adrianne Wallace-Povirk, Christina George, Steve Orr, Lisa Polin, Kathryn White, Juiwanna Kushner, Robert Morris, Aleem Gangjee, Larry H. Matherly	2017	38
19	Role of proton-coupled folate transporter in pemetrexed resistance of mesothelioma: clinical evidence and new pharmacological tools Annals of Oncology ·Elisa Giovannetti, Paolo Andrea Zucali, Yehuda G. Assaraf, Niccola Funel, Maria Gemelli, Michal Stark, Erik Thunnissen, Zhanjun Hou, Ittai B. Muller, Eduard A. Struys, Matteo Perrino, Gerrit Jansen, Larry H. Matherly, Godefridus J. Peters	2017	37
20	6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Regioisomers as Targeted Antifolates for Folate Receptor α and the Proton-Coupled Folate Transporter in Human Tumors Journal of Medicinal Chemistry ·Lei Wang, Adrianne Wallace-Povirk, Sudhir Raghavan, S.M. Deis, Mike R. Wilson, Si Yang, Lisa Polin, Kathryn White, Juiwanna Kushner, Steven Orr, Christina George, Carrie O’Connor, Zhanjun Hou, Shermaine Mitchell-Ryan, Charles E. Dann, Larry H. Matherly, Aleem Gangjee	2015	36

About Zhanjun Hou

Zhanjun Hou is a scholar working on Rheumatology, Molecular Biology, Infectious Diseases, Oncology and Pediatrics, Perinatology and Child Health, having authored 80 papers that have together received 2.0k indexed citations. Recurring topics across this work include Folate and B Vitamins Research (52 papers), Biochemical and Molecular Research (33 papers), HIV/AIDS drug development and treatment (25 papers), RNA modifications and cancer (11 papers), Cancer-related Molecular Pathways (7 papers), Bone and Joint Diseases (6 papers), Pharmacological Effects and Toxicity Studies (6 papers) and Cancer, Hypoxia, and Metabolism (6 papers). The work is most often cited by research in Rheumatology (909 citations), Infectious Diseases (318 citations), Biochemistry (125 citations), Physiology (77 citations) and Molecular Biology (1.1k citations). Zhanjun Hou has collaborated with scholars based in United States, China and Italy. Frequent co-authors include Larry H. Matherly, Aleem Gangjee, Yijun Deng, Sita Kugel Desmoulin, Christina Cherian, Mike R. Wilson, Bharati Mitra, Lisa Polin, Kathryn White and Juiwanna Kushner. Their work appears in journals such as Journal of Medicinal Chemistry, Cancer Research, Journal of Biological Chemistry, Molecular Pharmacology and Biochemical Journal.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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