Xichen Lin

1.2k citations

28 papers · 1k · h-index 16

Impact in

Immunology top 5%
- Psoriasis: Treatment and Pathogenesis
- T-cell and B-cell Immunology
Organic Chemistry top 5%
- Radical Photochemical Reactions
- Catalytic C–H Functionalization Methods
- Asymmetric Synthesis and Catalysis
- Advanced Synthetic Organic Chemistry
- Synthesis and biological activity

Papers in

Organic Chemistry 14
- Advanced Synthetic Organic Chemistry 4
- Synthesis and biological activity 4
- Radical Photochemical Reactions 3
- Synthesis and Characterization of Heterocyclic Compounds 2
- Catalytic C–H Functionalization Methods 2
Immunology 6
- Psoriasis: Treatment and Pathogenesis 6

Co-authors: Steven M. Weinreb (5 shared papers)Didier Stien (3 shared papers)Feng Ren (14 shared papers)Ting Yang (11 shared papers)Cuixiang Sun (1 shared paper)John D. Elliott (11 shared papers)Jia‐Ning Xiang (12 shared papers)Gerald D. Artman (1 shared paper)
Journals: ACS Medicinal Chemistry Letters (5 papers)Tetrahedron Letters (5 papers)Bioorganic & Medicinal Chemistry Letters (4 papers)Tetrahedron (3 papers)Bioorganic & Medicinal Chemistry (3 papers)
Partner nations: China United States United Kingdom

In The Last Decade

Xichen Lin

28 papers receiving 985 citations

Peers

Countries citing papers authored by Xichen Lin

Since Specialization

Citations

This map shows the geographic impact of Xichen Lin's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Xichen Lin with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Xichen Lin more than expected).

Fields of papers citing papers by Xichen Lin

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Xichen Lin. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Xichen Lin. The network helps show where Xichen Lin may publish in the future.

Co-authors

The 25 scholars most cited alongside Xichen Lin, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Xichen Lin Line = papers co-authored together Xichen Lin links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 28 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Small-Molecule RORγt Antagonists Inhibit T Helper 17 Cell Transcriptional Network by Divergent Mechanisms Immunity ·Sheng Xiao, Nir Yosef, Jianfei Yang, Yonghui Wang, Ling Zhou, Chen Ying Zhu, Chuan Wu, Erkan Baloglu	2014	248
2	Explorations on the Total Synthesis of the Unusual Marine Alkaloid Chartelline A The Journal of Organic Chemistry ·Cuixiang Sun, Xichen Lin, Steven M. Weinreb	2006	83
3	Discovery of Biaryl Amides as Potent, Orally Bioavailable, and CNS Penetrant RORγt Inhibitors ACS Medicinal Chemistry Letters ·Yonghui Wang, Yaobang Cheng, Ting Yang, Guifeng Zhang, Qinghua Meng, Fangbin Han, Yafei Huang, Ling Zhou	2015	73
4	Discovery of novel N-(5-(arylcarbonyl)thiazol-2-yl)amides and N-(5-(arylcarbonyl)thiophen-2-yl)amides as potent RORγt inhibitors Bioorganic & Medicinal Chemistry ·Yonghui Wang, Guifeng Zhang, Ting Yang, Qian Liu, Yaobang Cheng, Ling Zhou, Yingli Ma, Ziqiang Cheng	2013	65
5	Discovery of Tertiary Amine and Indole Derivatives as Potent RORγt Inverse Agonists ACS Medicinal Chemistry Letters ·Ting Yang, Qian Liu, Yaobang Cheng, Yingli Ma, Liuqing Yang, Qianqian Wu, Lisa A. Orband‐Miller, Ling Zhou	2013	63
6	Mild and Regioselective N-Alkylation of 2-Pyridones in Water Organic Letters ·Zhongmiao Xu, Hongfu Lu, Xuedong Dai, Ting Yang, Xichen Lin, Feng Ren +1 other	2015	54
7	A New Method for the Generation and Cyclization of Iminyl Radicals via the Hudson Reaction Organic Letters ·Xichen Lin, Didier Stien, Steven M. Weinreb	1999	47
8	Model studies on total synthesis of the chartellines, spirocyclic β-lactam alkaloids from a marine bryozoan Tetrahedron Letters ·Xichen Lin, Steven M. Weinreb	2001	47
9	Efficient and C2-selective arylation of indoles, benzofurans, and benzothiophenes with iodobenzenes in water at room temperature Tetrahedron ·Zhongmiao Xu, Yulong Xu, Hongfu Lu, Ting Yang, Xichen Lin, Liming Shao, Feng Ren	2015	42
10	A mild new procedure for production, cyclization and trapping of amidyl radicals: application to a formal total synthesis of peduncularine Tetrahedron Letters ·Xichen Lin, Didier Stien, Steven M. Weinreb	2000	38
11	Development of efficient new methodology for generation, cyclization and functional trapping of iminyl and amidyl radicals Tetrahedron ·Xichen Lin, Gerald D. Artman, Didier Stien, Steven M. Weinreb	2001	34
12	Discovery of N-(4-aryl-5-aryloxy-thiazol-2-yl)-amides as potent RORγt inverse agonists Bioorganic & Medicinal Chemistry ·Yonghui Wang, Ting Yang, Qian Liu, Yingli Ma, Liuqing Yang, Ling Ping Zhou, Zhijun Xiang, Ziqiang Cheng	2015	30
13	From RORγt Agonist to Two Types of RORγt Inverse Agonists ACS Medicinal Chemistry Letters ·Yonghui Wang, Ting Ao Tang, Qian Liu, Ting Yang, Liuqing Yang, Yingli Ma, Guifeng Zhang, Yafei Huang	2018	29
14	A mild and efficient carboxylate-directed C–H arylation of aryl carboxylic acids with iodobenzenes in water Tetrahedron Letters ·Zhongmiao Xu, Ting Yang, Xichen Lin, John D. Elliott, Feng Ren	2014	24
15	Discovery of Novel 1,2,4-Thiadiazole Derivatives as Potent, Orally Active Agonists of Sphingosine 1-Phosphate Receptor Subtype 1 (S1P1) Journal of Medicinal Chemistry ·Feng Ren, Guanghui Deng, Linbo Luan, Qinghua Meng, Qiongfeng Xu, Heng Xu, Haibo Zhang, Baowei Zhao	2012	22
16	Discovery of CNS Penetrant CXCR2 Antagonists for the Potential Treatment of CNS Demyelinating Disorders ACS Medicinal Chemistry Letters ·Heng Xu, Hongfu Lu, Zhongmiao Xu, Linbo Luan, Chengyong Li, Yan Xu, Kelly Dong, Xiong Li	2016	17
17	Novel complex crystal structure of prolyl hydroxylase domain-containing protein 2 (PHD2): 2,8-Diazaspiro[4.5]decan-1-ones as potent, orally bioavailable PHD2 inhibitors Bioorganic & Medicinal Chemistry ·Guanghui Deng, Yingli Ma, Qiongfeng Xu, Hailong Wang, Liuqing Yang, Qing Hua Zhang, Taylor B. Guo, Wei Zhang	2013	16
18	Discovery of Novel 1-Cyclopentenyl-3-phenylureas as Selective, Brain Penetrant, and Orally Bioavailable CXCR2 Antagonists Journal of Medicinal Chemistry ·Hongfu Lu, Ting Yang, Zhongmiao Xu, Xichen Lin, Yueting Zhang, Xin Cai, Kelly Dong, Sophie Gong	2018	16
19	Indole-propionic acid derivatives as potent, S1P3-sparing and EAE efficacious sphingosine-1-phosphate 1 (S1P1) receptor agonists Bioorganic & Medicinal Chemistry Letters ·Qinghua Meng, Baowei Zhao, Qiongfeng Xu, Guanghui Deng, Chengyong Li, Linbo Luan, Feng Ren, Heng Xu	2012	15
20	Chiral 2-aminopyrimidin-4(1H)-one derivative as the novel bifunctional organocatalyst: enantioselective Aldol reaction of isatins with ketones Tetrahedron ·Hongfu Lu, Jingtao Bai, Jianyu Xu, Ting Yang, Xichen Lin, Jian Li, Feng Ren	2015	14

About Xichen Lin

Xichen Lin is a scholar working on Organic Chemistry, Immunology, Cancer Research, Oncology and Computational Theory and Mathematics, having authored 28 papers that have together received 1k indexed citations. Recurring topics across this work include Psoriasis: Treatment and Pathogenesis (6 papers), Sphingolipid Metabolism and Signaling (4 papers), Advanced Synthetic Organic Chemistry (4 papers), Synthesis and biological activity (4 papers), Radical Photochemical Reactions (3 papers), Chemokine receptors and signaling (3 papers), Synthesis and Characterization of Heterocyclic Compounds (2 papers) and Catalytic C–H Functionalization Methods (2 papers). The work is most often cited by research in Immunology (366 citations), Organic Chemistry (465 citations), Computational Theory and Mathematics (50 citations), Endocrine and Autonomic Systems (16 citations) and Pharmaceutical Science (19 citations). Xichen Lin has collaborated with scholars based in China, United States and United Kingdom. Frequent co-authors include Steven M. Weinreb, Didier Stien, Feng Ren, Ting Yang, Cuixiang Sun, John D. Elliott, Jia‐Ning Xiang, Gerald D. Artman, Yingli Ma and Lisa A. Orband‐Miller. Their work appears in journals such as ACS Medicinal Chemistry Letters, Tetrahedron Letters, Bioorganic & Medicinal Chemistry Letters, Tetrahedron and Bioorganic & Medicinal Chemistry.

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