Tom Houben

2.0k citations

40 papers · 1.1k · 1 hit paper · h-index 17

Impact in

Epidemiology top 10%
- Liver Disease Diagnosis and Treatment
- Autophagy in Disease and Therapy
Cancer Research
- Protease and Inhibitor Mechanisms

Papers in

Molecular Biology 15
- Gut microbiota and health 4
- Sphingolipid Metabolism and Signaling 4
Epidemiology 14
- Liver Disease Diagnosis and Treatment 14

Co-authors: Ronit Shiri‐Sverdlov (38 shared papers)Tulasi Yadati (8 shared papers)Albert V. Bitorina (10 shared papers)Yvonne Oligschlaeger (21 shared papers)Marten H. Hofker (10 shared papers)Sofie M. A. Walenbergh (13 shared papers)Marion J. Gijbels (12 shared papers)Tim Hendrikx (13 shared papers)
Journals: Scientific Reports (4 papers)Journal of Lipid Research (3 papers)Frontiers in Immunology (3 papers)PLoS ONE (2 papers)BioMolecular Concepts (2 papers)
Partner nations: Netherlands Germany Belgium

In The Last Decade

Tom Houben

39 papers receiving 1.0k citations

Tom Houben's Hit Papers

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The Ins and Outs of Cathepsins: Physiological Function and Role in Disease Management 2020 · 313 citations

Peers

Countries citing papers authored by Tom Houben

Since Specialization

Citations

This map shows the geographic impact of Tom Houben's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Tom Houben with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Tom Houben more than expected).

Fields of papers citing papers by Tom Houben

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Tom Houben. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Tom Houben. The network helps show where Tom Houben may publish in the future.

Co-authors

The 25 scholars most cited alongside Tom Houben, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Tom Houben Line = papers co-authored together Tom Houben links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 40 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	The Ins and Outs of Cathepsins: Physiological Function and Role in Disease Management Cells ·Tulasi Yadati, Tom Houben, Albert V. Bitorina, Ronit Shiri‐Sverdlov Hit paper breakdown →	2020	313
2	Modulation of the gut microbiota impacts nonalcoholic fatty liver disease: a potential role for bile acids Journal of Lipid Research ·Aafke W. F. Janssen, Tom Houben, Saeed Katiraei, Wieneke Dijk, Lily Boutens, Nieke van der Bolt, Zeneng Wang, J. Mark Brown, Stanley L. Hazen, Stéphane Mandard, Ronit Shiri‐Sverdlov, Folkert Kuipers, Ko Willems van Dijk, Jacques Vervoort, Rinke Stienstra, Guido Hooiveld, Sander Kersten	2017	98
3	Inflammatory Bowel Disease: A Stressed “Gut/Feeling” Cells ·Yvonne Oligschlaeger, Tulasi Yadati, Tom Houben, Claudia Maria Condello Oliván, Ronit Shiri‐Sverdlov	2019	84
4	Bone marrow‐specific caspase‐1/11 deficiency inhibits atherosclerosis development in Ldlr^−/− mice FEBS Journal ·Tim Hendrikx, Mike L. J. Jeurissen, Patrick J. van Gorp, Marion J. Gijbels, Sofie M. A. Walenbergh, Tom Houben, Rick van Gorp, Chantal C. H. Pöttgens, Rinke Stienstra, Mihai G. Netea, Marten H. Hofker, Marjo M. P. C. Donners, Ronit Shiri‐Sverdlov	2015	60
5	Cathepsin D regulates lipid metabolism in murine steatohepatitis Scientific Reports ·Tom Houben, Yvonne Oligschlaeger, Tim Hendrikx, Albert V. Bitorina, Sofie M. A. Walenbergh, Patrick J. van Gorp, Marion J. Gijbels, Silvia Friedrichs, Jogchum Plat, Frank G. Schaap, Dieter Lütjohann, Marten H. Hofker, Ronit Shiri‐Sverdlov	2017	50
6	The immunity–diet–microbiota axis in the development of metabolic syndrome Current Opinion in Lipidology ·Eelke Brandsma, Tom Houben, Jingyuan Fu, Ronit Shiri‐Sverdlov, Marten H. Hofker	2015	44
7	Plasma Cathepsin D Levels: A Novel Tool to Predict Pediatric Hepatic Inflammation The American Journal of Gastroenterology ·Sofie M. A. Walenbergh, Tom Houben, Tim Hendrikx, Mike L. J. Jeurissen, Patrick J. van Gorp, Anita Vreugdenhil, Marlou Adriaanse, Wim A. Buurman, Marten H. Hofker, Antonella Mosca, Patrick Lindsey, Anna Alisi, Daniela Liccardo, Nadia Panera, Ger H. Koek, Valério Nobili, Ronit Shiri‐Sverdlov	2015	38
8	Plasma cathepsin D correlates with histological classifications of fatty liver disease in adults and responds to intervention Scientific Reports ·Sofie M. A. Walenbergh, Tom Houben, Sander S. Rensen, Veerle Bieghs, Tim Hendrikx, Patrick J. van Gorp, Yvonne Oligschlaeger, Mike L. J. Jeurissen, Marion J. Gijbels, Wim A. Buurman, Anita Vreugdenhil, Jan Greve, Jogchum Plat, Marten H. Hofker, Satish C. Kalhan, Jussi Pihlajamäki, Patrick Lindsey, Ger H. Koek, Ronit Shiri‐Sverdlov	2016	36
9	Oxidized LDL at the crossroads of immunity in non-alcoholic steatohepatitis Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids ·Tom Houben, Eelke Brandsma, Sofie M. A. Walenbergh, Marten H. Hofker, Ronit Shiri‐Sverdlov	2016	26
10	Hematopoietic overexpression of Cyp27a1 reduces hepatic inflammation independently of 27-hydroxycholesterol levels in Ldlr−/− mice Journal of Hepatology ·Tim Hendrikx, Mike L. J. Jeurissen, Veerle Bieghs, Sofie M. A. Walenbergh, Patrick J. van Gorp, Fons Verheyen, Tom Houben, Yasmin Dias Guichot, Marion J. Gijbels, Eran Leitersdorf, Marten H. Hofker, Dieter Lütjohann, Ronit Shiri‐Sverdlov	2014	26
11	Prevention of oxLDL uptake leads to decreased atherosclerosis in hematopoietic NPC1-deficient Ldlr−/− mice Atherosclerosis ·Mike L. J. Jeurissen, Sofie M. A. Walenbergh, Tom Houben, Marion J. Gijbels, Jieyi Li, Tim Hendrikx, Yvonne Oligschlaeger, Patrick J. van Gorp, Christoph J. Binder, Marjo M. P. C. Donners, Ronit Shiri‐Sverdlov	2016	22
12	Plasma cathepsin D activity is negatively associated with hepatic insulin sensitivity in overweight and obese humans Diabetologia ·Lingling Ding, Gijs H. Goossens, Yvonne Oligschlaeger, Tom Houben, Ellen E. Blaak, Ronit Shiri‐Sverdlov	2019	21
13	Blood-derived macrophages prone to accumulate lysosomal lipids trigger oxLDL-dependent murine hepatic inflammation Scientific Reports ·Tom Houben, Yvonne Oligschlaeger, Albert V. Bitorina, Tim Hendrikx, Sofie M. A. Walenbergh, Marie-Hélène Lenders, Marion J. Gijbels, Fons Verheyen, Dieter Lütjohann, Marten H. Hofker, Christoph J. Binder, Ronit Shiri‐Sverdlov	2017	20
14	Inhibiting Extracellular Cathepsin D Reduces Hepatic Steatosis in Sprague–Dawley Rats Biomolecules ·Princy Khurana, Tulasi Yadati, Sandeep Goyal, Atul Dolas, Tom Houben, Yvonne Oligschlaeger, Anil K. Agarwal, Aditya Kulkarni, Ronit Shiri‐Sverdlov	2019	19
15	Plasma Cathepsin D Activity Rather Than Levels Correlates With Metabolic Parameters of Type 2 Diabetes in Male Individuals Frontiers in Endocrinology ·Lingling Ding, Tom Houben, Yvonne Oligschlaeger, Albert V. Bitorina, Bart J. Verwer, Maarten E. Tushuizen, Ronit Shiri‐Sverdlov	2020	19
16	Inhibition of Extracellular Cathepsin D Reduces Hepatic Lipid Accumulation and Leads to Mild Changes in Inflammationin NASH Mice Frontiers in Immunology ·Tulasi Yadati, Tom Houben, Albert V. Bitorina, Yvonne Oligschlaeger, Marion J. Gijbels, Ronny Mohren, Dieter Lütjohann, Princy Khurana, Sandeep Goyal, Aditya Kulkarni, Jan Theys, Berta Cillero‐Pastor, Ronit Shiri‐Sverdlov	2021	18
17	MSP is a negative regulator of inflammation and lipogenesis in ex vivo models of non-alcoholic steatohepatitis Experimental & Molecular Medicine ·Dipanjan Chanda, Jieyi Li, Yvonne Oligschlaeger, Mike L. J. Jeurissen, Tom Houben, Sofie M. A. Walenbergh, Ronit Shiri‐Sverdlov, Dietbert Neumann	2016	16
18	Macrophage Stimulating Protein Enhances Hepatic Inflammation in a NASH Model PLoS ONE ·Jieyi Li, Dipanjan Chanda, Patrick J. van Gorp, Mike L. J. Jeurissen, Tom Houben, Sofie M. A. Walenbergh, J.M.H. Debets, Yvonne Oligschlaeger, Marion J. Gijbels, Dietbert Neumann, Ronit Shiri‐Sverdlov	2016	15
19	Cysteamine Decreases Low‐Density Lipoprotein Oxidation, Causes Regression of Atherosclerosis, and Improves Liver and Muscle Function in Low‐Density Lipoprotein Receptor–Deficient Mice Journal of the American Heart Association ·Feroz Ahmad, Robert D. Mitchell, Tom Houben, Angela Palo, Tulasi Yadati, Andrew Parnell, Ketan Patel, Ronit Shiri‐Sverdlov, David S. Leake	2021	13
20	Weekly Treatment of 2-Hydroxypropyl-β-cyclodextrin Improves Intracellular Cholesterol Levels in LDL Receptor Knockout Mice International Journal of Molecular Sciences ·Sofie M. A. Walenbergh, Tom Houben, Tim Hendrikx, Mike L. J. Jeurissen, Patrick J. van Gorp, Nathalie Vaes, Steven W.M. Olde Damink, Fons Verheyen, Ger H. Koek, Dieter Lütjohann, Alena Grebe, Eicke Latz, Ronit Shiri‐Sverdlov	2015	12

About Tom Houben

Tom Houben is a scholar working on Molecular Biology, Epidemiology, Surgery, Physiology and Cardiology and Cardiovascular Medicine, having authored 40 papers that have together received 1.1k indexed citations. Recurring topics across this work include Liver Disease Diagnosis and Treatment (14 papers), Cholesterol and Lipid Metabolism (6 papers), Lipid metabolism and disorders (6 papers), Lysosomal Storage Disorders Research (5 papers), Endoplasmic Reticulum Stress and Disease (4 papers), Gut microbiota and health (4 papers), Sphingolipid Metabolism and Signaling (4 papers) and Atherosclerosis and Cardiovascular Diseases (4 papers). The work is most often cited by research in Epidemiology (318 citations), Cancer Research (104 citations), Physiology (178 citations), Physiology (34 citations) and Cell Biology (117 citations). Tom Houben has collaborated with scholars based in Netherlands, Germany and Belgium. Frequent co-authors include Ronit Shiri‐Sverdlov, Tulasi Yadati, Albert V. Bitorina, Yvonne Oligschlaeger, Marten H. Hofker, Sofie M. A. Walenbergh, Marion J. Gijbels, Tim Hendrikx, Patrick J. van Gorp and Mike L. J. Jeurissen. Their work appears in journals such as Scientific Reports, Journal of Lipid Research, Frontiers in Immunology, PLoS ONE and BioMolecular Concepts.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Tom Houben

Impact in

Papers in i

In The Last Decade

Tom Houben

Tom Houben's Hit Papers

Peers

Countries citing papers authored by Tom Houben

Fields of papers citing papers by Tom Houben

All Works

About Tom Houben

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