Phillip P. Sharp

6.4k citations

21 papers · 4.7k · 2 hit papers · h-index 17

Impact in

Infectious Diseases top 0.5%
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
Computational Theory and Mathematics top 1%
- Computational Drug Discovery Methods

Papers in

Organic Chemistry 6
- Carbohydrate Chemistry and Synthesis 2
- Cyclopropane Reaction Mechanisms 1
Molecular Biology 10
- Protein Degradation and Inhibitors 5
- RNA and protein synthesis mechanisms 2

Co-authors: Christopher J. Burns (6 shared papers)Jean‐Marc Garnier (3 shared papers)Martin G. Banwell (4 shared papers)Carl R. Walkley (2 shared papers)Scott Taylor (2 shared papers)Anthony C. Willis (3 shared papers)Andrew C.W. Zannettino (1 shared paper)David C.S. Huang (4 shared papers)
Journals: The Journal of Organic Chemistry (2 papers)Nature Chemical Biology (2 papers)MedChemComm (1 paper)Nature Communications (1 paper)Nature Immunology (1 paper)
Partner nations: Australia United States China

In The Last Decade

Phillip P. Sharp

21 papers receiving 4.6k citations

Phillip P. Sharp's Hit Papers

align trajectories log scale

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing 2020 · 3.4k citations

What are hit papers?

Paper score: A paper's citations measured against the top-1% bar of its own field and year: the square root of citations ÷ bar, so 1 means right at the bar and 2 means four times its citations. The bar blends the citation counts that enter the top 1% of the paper's subfields in its year (weighted 89.5%), of those subfields over all years (0.5%) and of its year across all fields (10%); a subfield and year with fewer than 400 papers takes its year's bar. Papers from 2026 are not scored yet: in an unfinished year, when a paper appeared matters more than how it is cited.

Hit paper: A paper cited at least 1.5× the top-1% bar of its field and year: a paper score of at least √1.5.

2020 Nature
2018 Cell

Peers

Countries citing papers authored by Phillip P. Sharp

Since Specialization

Citations

This map shows the geographic impact of Phillip P. Sharp's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Phillip P. Sharp with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Phillip P. Sharp more than expected).

Fields of papers citing papers by Phillip P. Sharp

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Phillip P. Sharp. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Phillip P. Sharp. The network helps show where Phillip P. Sharp may publish in the future.

Co-authors

The 25 scholars most cited alongside Phillip P. Sharp, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Phillip P. Sharp Line = papers co-authored together Phillip P. Sharp links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 21 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	A SARS-CoV-2 protein interaction map reveals targets for drug repurposing Nature ·David Ezra Gordon, Gwendolyn Μ. Jang, Mehdi Bouhaddou, Jiewei Xu, Kirsten Obernier, Kris M. White, Matthew J. O’Meara, Veronica V. Rezelj Hit paper breakdown →	2020	3434
2	CIS is a potent checkpoint in NK cell–mediated tumor immunity Nature Immunology ·Rebecca B. Delconte, Tatiana B. Kolesnik, Laura F. Dagley, Jai Rautela, Wei Shi, Eva Maria Putz, Kimberley A. Stannard, Jian‐Guo Zhang	2016	314
3	Comparative Flavivirus-Host Protein Interaction Mapping Reveals Mechanisms of Dengue and Zika Virus Pathogenesis Cell ·Priya S. Shah, Nichole Link, Gwendolyn Μ. Jang, Phillip P. Sharp, Tongtong Zhu, Danielle L. Swaney, Jeffrey R. Johnson, John Von Dollen Hit paper breakdown →	2018	267
4	A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production Nature Communications ·Ueli Nachbur, Che A. Stafford, Aleksandra Bankovacki, Yifan Zhan, Lisa Lindqvist, Berthe Katrine Fiil, Yelena Khakham, Hyun‐Ja Ko	2015	113
5	BET bromodomain inhibitors: a patent review Expert Opinion on Therapeutic Patents ·Jean‐Marc Garnier, Phillip P. Sharp, Christopher J. Burns	2013	106
6	BET inhibitors induce apoptosis through a MYC independent mechanism and synergise with CDK inhibitors to kill osteosarcoma cells Scientific Reports ·Scott Taylor, Ankita Gupte, Phillip P. Sharp, Mannu Walia, Nicole C. Walsh, Andrew C.W. Zannettino, Alistair Morgan Chalk, Christopher J. Burns	2015	106
7	Consecutive Gold(I)-Catalyzed Cyclization Reactions of o -(Buta-1,3-diyn-1-yl-)-Substituted N -Aryl Ureas: A One-Pot Synthesis of Pyrimido[1,6- a ]indol-1(2 H )-ones and Related Systems Organic Letters ·Phillip P. Sharp, Martin G. Banwell, Jens Renner, Klaas Lohmann, Anthony C. Willis	2013	46
8	A small molecule interacts with VDAC2 to block mouse BAK-driven apoptosis Nature Chemical Biology ·Mark F. van Delft, Stéphane Chappaz, Yelena Khakham, Chinh T. Bui, Marlyse A. Debrincat, Kym N. Lowes, Jason M. Brouwer, Christoph Grohmann	2019	36
9	BET inhibition represses miR17-92 to drive BIM-initiated apoptosis of normal and transformed hematopoietic cells Leukemia ·Zhen Xu, Phillip P. Sharp, Yuan Yao, David Segal, Ching‐Seng Ang, Seong Lin Khaw, Brandon J. Aubrey, Jianan Gong	2016	30
10	Design, Synthesis, and Biological Activity of 1,2,3-Triazolobenzodiazepine BET Bromodomain Inhibitors ACS Medicinal Chemistry Letters ·Phillip P. Sharp, Jean‐Marc Garnier, Tamás Hatfaludi, Zhen Xu, David Segal, Kate E. Jarman, Hélène Jousset, Alexandra L. Garnham	2017	29
11	Dichlorocarbene adducts of alkyl enol ethers as precursors to furans: application to a total synthesis of the furanosesquiterpene (±)-pallescensin A Tetrahedron Letters ·Jonathan S. Foot, A.T. Phillis, Phillip P. Sharp, Anthony C. Willis, Martin G. Banwell	2006	26
12	Synthesis of rhamnosylated arginine glycopeptides and determination of the glycosidic linkage in bacterial elongation factor P Chemical Science ·Siyao Wang, Leo Corcilius, Phillip P. Sharp, Andrei Rajkovic, Michael Ibba, Benjamin L. Parker, Richard J. Payne	2016	26
13	Evaluation of functional groups as acetyl-lysine mimetics for BET bromodomain inhibition MedChemComm ·Phillip P. Sharp, Jean‐Marc Garnier, David C.S. Huang, Christopher J. Burns	2014	24
14	Signal peptide mimicry primes Sec61 for client-selective inhibition Nature Chemical Biology ·Shahid Rehan, Dale Tranter, Phillip P. Sharp, Gregory B. Craven, Janet L. Anderl, Tony Muchamuel, Vahid Abrishami, Suvi H. Kuivanen	2023	24
15	Inhibitors of Eukaryotic Translational Machinery as Therapeutic Agents Journal of Medicinal Chemistry ·Angela PC Fan, Phillip P. Sharp	2021	21
16	Total Syntheses of the 3H-Pyrrolo[2,3-c]quinolone-Containing Alkaloids Marinoquinolines A–F, K, and Aplidiopsamine A Using a Palladium-Catalyzed Ullmann Cross-Coupling/Reductive Cyclization Pathway The Journal of Organic Chemistry ·Benoît Bolte, Christopher S. Bryan, Phillip P. Sharp, Soheil Sayyahi, Charly Rihouey, Amy Kendrick, Ping Lan, Martin G. Banwell	2019	19
17	Simplified Silvestrol Analogues with Potent Cytotoxic Activity ChemMedChem ·Bill C. Hawkins, Lisa Lindqvist, Duong Nhu, Phillip P. Sharp, David Segal, Andrew K. Powell, Eileen Ryan, Jennifer M. Chambers	2014	18
18	Synthesis of a GlcNAcylated arginine building block for the solid phase synthesis of death domain glycopeptide fragments Bioorganic & Medicinal Chemistry ·Siyao Wang, Leo Corcilius, Phillip P. Sharp, Richard J. Payne	2017	10
19	Inhibition of the Sec61 translocon overcomes cytokine‐induced glucocorticoid resistance in T‐cell acute lymphoblastic leukaemia British Journal of Haematology ·Lauren K. Meyer, Cristina Delgado-Martín, Phillip P. Sharp, Benjamin J. Huang, Dustin L. McMinn, Tiffaney L. Vincent, Theresa M. Ryan, Terzah M. Horton	2022	8
20	Mechanistic Studies on the Base-Promoted Conversion of Alkoxy-Substituted, Ring-Fused gem -Dihalocyclopropanes into Furans: Evidence for a Process Involving Electrocyclic Ring Closure of a Carbonyl Ylide Intermediate The Journal of Organic Chemistry ·Phillip P. Sharp, Jiří Mikušek, Junming Ho, Elizabeth H. Krenske, Martin G. Banwell, Michelle L. Coote, Jas S. Ward, Anthony C. Willis	2018	6

About Phillip P. Sharp

Phillip P. Sharp is a scholar working on Organic Chemistry, Molecular Biology, Cancer Research, Infectious Diseases and Immunology, having authored 21 papers that have together received 4.7k indexed citations. Recurring topics across this work include Protein Degradation and Inhibitors (5 papers), RNA and protein synthesis mechanisms (2 papers), Carbohydrate Chemistry and Synthesis (2 papers), SARS-CoV-2 and COVID-19 Research (2 papers), Cyclopropane Reaction Mechanisms (1 paper), Endoplasmic Reticulum Stress and Disease (1 paper), NF-κB Signaling Pathways (1 paper) and Cellular transport and secretion (1 paper). The work is most often cited by research in Infectious Diseases (2.1k citations), Computational Theory and Mathematics (450 citations), Immunology (497 citations), Molecular Biology (1.3k citations) and General Dentistry (5 citations). Phillip P. Sharp has collaborated with scholars based in Australia, United States and China. Frequent co-authors include Christopher J. Burns, Jean‐Marc Garnier, Martin G. Banwell, Carl R. Walkley, Scott Taylor, Anthony C. Willis, Andrew C.W. Zannettino, David C.S. Huang, Nicole C. Walsh and Mannu Walia. Their work appears in journals such as The Journal of Organic Chemistry, Nature Chemical Biology, MedChemComm, Nature Communications and Nature Immunology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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In The Last Decade

Phillip P. Sharp

Phillip P. Sharp's Hit Papers

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Fields of papers citing papers by Phillip P. Sharp

All Works

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