Philip Mitchell

3.5k citations

34 papers · 3.0k · 1 hit paper · h-index 24

Impact in

Molecular Biology top 2%
- RNA and protein synthesis mechanisms
- RNA Research and Splicing
- RNA modifications and cancer
- RNA regulation and disease
- Fungal and yeast genetics research
- Nuclear Structure and Function
- RNA Interference and Gene Delivery
Structural Biology top 10%

Papers in

Molecular Biology 32
- RNA and protein synthesis mechanisms 25
- RNA Research and Splicing 24
- RNA modifications and cancer 20
- Fungal and yeast genetics research 4
- Heat shock proteins research 2
- RNA Interference and Gene Delivery 2
- Connexins and lens biology 2
Genetics 2
- Bacterial Genetics and Biotechnology 2

Co-authors: David Tollervey (9 shared papers)Elisabeth Petfalski (2 shared papers)Matthias Mann (2 shared papers)Andrej Shevchenko (1 shared paper)Richard Brimacombe (8 shared papers)Monika Osswald (6 shared papers)E Petfalski (2 shared papers)Dmitry E. Bochkariov (2 shared papers)
Journals: Nucleic Acids Research (4 papers)The EMBO Journal (2 papers)RNA (2 papers)Advances in experimental medicine and biology (2 papers)Genes & Development (2 papers)
Partner nations: United Kingdom Germany United States

In The Last Decade

Philip Mitchell

34 papers receiving 3.0k citations

Philip Mitchell's Hit Papers

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The Exosome: A Conserved Eukaryotic RNA Processing Complex Containing Multiple 3′→5′ Exoribonucleases 1997 · 809 citations

Peers

Countries citing papers authored by Philip Mitchell

Since Specialization

Citations

This map shows the geographic impact of Philip Mitchell's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Philip Mitchell with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Philip Mitchell more than expected).

Fields of papers citing papers by Philip Mitchell

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Philip Mitchell. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Philip Mitchell. The network helps show where Philip Mitchell may publish in the future.

Co-authors

The 25 scholars most cited alongside Philip Mitchell, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Philip Mitchell Line = papers co-authored together Philip Mitchell links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 34 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	The Exosome: A Conserved Eukaryotic RNA Processing Complex Containing Multiple 3′→5′ Exoribonucleases Cell ·Philip Mitchell, Elisabeth Petfalski, Andrej Shevchenko, Matthias Mann, David Tollervey Hit paper breakdown →	1997	809
2	mRNA stability in eukaryotes Current Opinion in Genetics & Development ·Philip Mitchell, David Tollervey	2000	246
3	The POP1 gene encodes a protein component common to the RNase MRP and RNase P ribonucleoproteins. Genes & Development ·Zoi Lygerou, Philip Mitchell, E Petfalski, Bertrand Séraphin, David Tollervey	1994	191
4	The 3' end of yeast 5.8S rRNA is generated by an exonuclease processing mechanism. Genes & Development ·Philip Mitchell, E Petfalski, David Tollervey	1996	174
5	An NMD Pathway in Yeast Involving Accelerated Deadenylation and Exosome-Mediated 3′→5′ Degradation Molecular Cell ·Philip Mitchell, David Tollervey	2003	172
6	Rrp47p Is an Exosome-Associated Protein Required for the 3′ Processing of Stable RNAs Molecular and Cellular Biology ·Philip Mitchell, Elisabeth Petfalski, Rym Houalla, Alexandre V. Podtelejnikov, Matthias Mann, David Tollervey	2003	141
7	mRNA turnover Current Opinion in Cell Biology ·Philip Mitchell, David Tollervey	2001	130
8	Clustering of modified nucleotides at the functional center of bacterial ribosomal RNA. The FASEB Journal ·Richard Brimacombe, Philip Mitchell, Monika Osswald, Katrin Stade, Dmitry E. Bochkariov	1993	117
9	Musing on the structural organization of the exosome complex. Nature Structural Biology ·Philip Mitchell, David Tollervey	2000	113
10	Identification of intermolecular RNA cross-links at the subunit interface of the Escherichia coli ribosome Biochemistry ·Philip Mitchell, Monika Osswald, Richard Brimacombe	1992	103
11	The decoding region of 16S RNA; a cross‐linking study of the ribosomal A, P and E sites using tRNA derivatized at position 32 in the anticodon loop. The EMBO Journal ·Thomas Döring, Philip Mitchell, Monika Osswald, Dmitry E. Bochkariov, Richard Brimacombe	1994	91
12	The exosome‐binding factors Rrp6 and Rrp47 form a composite surface for recruiting the Mtr4 helicase The EMBO Journal ·Benjamin Schuch, Monika Feigenbutz, Débora L. Makino, Sebastian Falk, Claire Basquin, Philip Mitchell, Elena Conti	2014	89
13	Selective isolation and detailed analysis of intra-RNA cross-links induced in the large ribosomal subunit of E. coli: a model for the tertiary structure of the tRNA binding domain in 23S RNA Nucleic Acids Research ·Philip Mitchell, Monika Osswald, D. Schueler, Richard Brimacombe	1990	77
14	The PMC2NT domain of the catalytic exosome subunit Rrp6p provides the interface for binding with its cofactor Rrp47p, a nucleic acid-binding protein Nucleic Acids Research ·Jonathan A. Stead, (unknown), Michaela J. Livingstone, Philip Mitchell	2007	73
15	How are tRNAs and mRNA arranged in the ribosome? An attempt to correlate the stereochemistry of the tRNA-mRNA interaction with constraints imposed by the ribosomal topography Nucleic Acids Research ·Valery I. Lim, Česlovas Venclovas, Alexander S. Spirin, Richard Brimacombe, Philip Mitchell, Florian Müller	1992	58
16	Methylation sites in Escherichia coli ribosomal RNA: Localization and identification of four new sites of methylation in 23 S rRNA Biochemistry ·Joseph Smith, Barry S. Cooperman, Philip Mitchell	1992	58
17	Rrp6, Rrp47 and Cofactors of the Nuclear Exosome Advances in experimental medicine and biology ·J. Scott Butler, Philip Mitchell	2010	49
18	The ontogeny of nexuses (gap junctions) in the ovary of the fetal mouse The Anatomical Record ·Philip Mitchell, Robert C. Burghardt	1986	46
19	Site-directed cross-linking studies on theE.colitRNA ribosome complex: determination of sites labelled with an aromatic azide attached to the variable loop or aminoacyl group of tRNA Nucleic Acids Research ·Philip Mitchell, Katrin Stade, Monika Oβwald, Richard Brimacombe	1993	40
20	The C-terminal Region of the Exosome-associated Protein Rrp47 Is Specifically Required for Box C/D Small Nucleolar RNA 3′-Maturation Journal of Biological Chemistry ·(unknown), Jonathan A. Stead, Monika Feigenbutz, Rebecca M. Jones, Philip Mitchell	2010	36

About Philip Mitchell

Philip Mitchell is a scholar working on Molecular Biology, Genetics, Organic Chemistry, Ecology and Agronomy and Crop Science, having authored 34 papers that have together received 3.0k indexed citations. Recurring topics across this work include RNA and protein synthesis mechanisms (25 papers), RNA Research and Splicing (24 papers), RNA modifications and cancer (20 papers), Fungal and yeast genetics research (4 papers), Heat shock proteins research (2 papers), RNA Interference and Gene Delivery (2 papers), Connexins and lens biology (2 papers) and Bacterial Genetics and Biotechnology (2 papers). The work is most often cited by research in Molecular Biology (2.8k citations), Structural Biology (26 citations), Cancer Research (129 citations), Genetics (217 citations) and Endocrinology (33 citations). Philip Mitchell has collaborated with scholars based in United Kingdom, Germany and United States. Frequent co-authors include David Tollervey, Elisabeth Petfalski, Matthias Mann, Andrej Shevchenko, Richard Brimacombe, Monika Osswald, E Petfalski, Dmitry E. Bochkariov, Zoi Lygerou and Bertrand Séraphin. Their work appears in journals such as Nucleic Acids Research, The EMBO Journal, RNA, Advances in experimental medicine and biology and Genes & Development.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Philip Mitchell's Hit Papers

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About Philip Mitchell

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