Peter P. Roller

12.4k citations

183 papers · 10.4k · 2 hit papers · h-index 56

Impact in

Toxicology top 0.2%
Molecular Biology top 0.5%
- Chemical Synthesis and Analysis
- Cell death mechanisms and regulation
- Protein Tyrosine Phosphatases
- Protein Kinase Regulation and GTPase Signaling
- Prion Diseases and Protein Misfolding
- Ubiquitin and proteasome pathways

Papers in

Molecular Biology 124
- Chemical Synthesis and Analysis 35
- Protein Kinase Regulation and GTPase Signaling 25
- Cell death mechanisms and regulation 14
- Protein Tyrosine Phosphatases 12
- PI3K/AKT/mTOR signaling in cancer 10
- Glycosylation and Glycoproteins Research 9
Organic Chemistry 36
- Carbohydrate Chemistry and Synthesis 12

Co-authors: Shaomeng Wang (24 shared papers)Zaneta Nikolovska‐Coleska (17 shared papers)Krzysztof Krajewski (17 shared papers)Terrence R. Burke (21 shared papers)York Tomita (9 shared papers)Jeanne A. Stuckey (10 shared papers)Jiri Safar (4 shared papers)Harry V. Gelboin (7 shared papers)
Journals: Journal of Biological Chemistry (19 papers)Bioorganic & Medicinal Chemistry Letters (13 papers)Biochemical and Biophysical Research Communications (13 papers)Journal of Medicinal Chemistry (12 papers)Biochemistry (10 papers)
Partner nations: United States China United Kingdom

In The Last Decade

Peter P. Roller

180 papers receiving 9.9k citations

Peter P. Roller's Hit Papers

align trajectories log scale

Structure-Based Design of Spiro-oxindoles as Potent, Specific Small-Molecule Inhibitors of the MDM2−p53 Interaction 2006 · 607 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2006 Journal of Medicinal Chemistry
2005 Journal of the American Chemical Society

Peers

Countries citing papers authored by Peter P. Roller

Since Specialization

Citations

This map shows the geographic impact of Peter P. Roller's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Peter P. Roller with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Peter P. Roller more than expected).

Fields of papers citing papers by Peter P. Roller

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Peter P. Roller. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Peter P. Roller. The network helps show where Peter P. Roller may publish in the future.

Co-authors

The 25 scholars most cited alongside Peter P. Roller, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Peter P. Roller Line = papers co-authored together Peter P. Roller links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Showing the 20 most-cited of 183 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Structure-Based Design of Spiro-oxindoles as Potent, Specific Small-Molecule Inhibitors of the MDM2−p53 Interaction Journal of Medicinal Chemistry ·Ke Ding, Yipin Lu, Zaneta Nikolovska‐Coleska, Guoping Wang, Su Qiu, Sanjeev Shangary, Wei Gao, Dongguang Qin, Jeanne A. Stuckey, Krzysztof Krajewski, Peter P. Roller, Shaomeng Wang Hit paper breakdown →	2006	607
2	Structure-Based Design of Potent Non-Peptide MDM2 Inhibitors Journal of the American Chemical Society ·Ke Ding, Yipin Lu, Zaneta Nikolovska‐Coleska, Su Qiu, Yousong Ding, Wei Gao, Jeanne A. Stuckey, Krzysztof Krajewski, Peter P. Roller, York Tomita, Damon A. Parrish, Jeffrey R. Deschamps, Shaomeng Wang Hit paper breakdown →	2005	571
3	Development and optimization of a binding assay for the XIAP BIR3 domain using fluorescence polarization Analytical Biochemistry ·Zaneta Nikolovska‐Coleska, Renxiao Wang, Xueliang Fang, Hongguang Pan, York Tomita, Peng Li, Peter P. Roller, Krzysztof Krajewski, Naoyuki G. Saito, Jeanne A. Stuckey, Shaomeng Wang	2004	452
4	Conformational transitions, dissociation, and unfolding of scrapie amyloid (prion) protein. Journal of Biological Chemistry ·Jiri Safar, Peter P. Roller, D. C. Gajdusek, C. J. Gibbs	1993	315
5	Discovery of Embelin as a Cell-Permeable, Small-Molecular Weight Inhibitor of XIAP through Structure-Based Computational Screening of a Traditional Herbal Medicine Three-Dimensional Structure Database Journal of Medicinal Chemistry ·Zaneta Nikolovska‐Coleska, Liang Xu, Zengjian Hu, York Tomita, Peng Li, Peter P. Roller, Renxiao Wang, Xueliang Fang, Ribo Guo, Manchao Zhang, Marc E. Lippman, Dajun Yang, Shaomeng Wang	2004	286
6	Discovery of Small-Molecule Inhibitors of Bcl-2 through Structure-Based Computer Screening Journal of Medicinal Chemistry ·Istvan Enyedy, Yan Ling, Kassoum Nacro, York Tomita, Xihan Wu, Yeyu Cao, Ribo Guo, Bihua Li, Xiaofeng Zhu, Ying Huang, Ya‐Qiu Long, Peter P. Roller, Dajun Yang, Shaomeng Wang	2001	243
7	Structure-Based Design of Potent Small-Molecule Inhibitors of Anti-Apoptotic Bcl-2 Proteins Journal of Medicinal Chemistry ·Guoping Wang, Zaneta Nikolovska‐Coleska, Chao‐Yie Yang, Renxiao Wang, Guozhi Tang, Jie Guo, Sanjeev Shangary, Su Qiu, Wei Gao, Dajun Yang, Jennifer L. Meagher, Jeanne A. Stuckey, Krzysztof Krajewski, Sheng Jiang, Peter P. Roller, Hatice Özel Abaan, York Tomita, Shaomeng Wang	2006	240
8	Identification of Cell Binding Sites in the Laminin α1 Chain Carboxyl-terminal Globular Domain by Systematic Screening of Synthetic Peptides Journal of Biological Chemistry ·Motoyoshi Nomizu, Woo Ho Kim, Keizo Yamamura, Atsushi Utani, Sang‐Yong Song, Akira Otaka, Peter P. Roller, Hynda K. Kleinman, Yoshihiko Yamada	1995	229
9	The amino terminus of ADP-ribosylation factor (ARF) is a critical determinant of ARF activities and is a potent and specific inhibitor of protein transport. Journal of Biological Chemistry ·Richard Kahn, Paul A. Randazzo, T Serafini, O Weiss, C Rulka, J Clark, M Amherdt, Peter P. Roller, Lelio Orci, James E. Rothman	1992	229
10	Syp (SH-PTP2) is a positive mediator of growth factor-stimulated mitogenic signal transduction. Journal of Biological Chemistry ·Shuting Xiao, D W Rose, Toshiyasu Sasaoka, Hiroshi Maegawa, Terrence R. Burke, Peter P. Roller, Steven E. Shoelson, Jerrold M. Olefsky	1994	223
11	Enzymatic conversion of benzo(a)pyrene leading predominantly to the diol-epoxide r-7,t-8-dihydroxy-t-9,10-oxy-7,8,9,10-tetrahydrobenzo(a)pyrene through a single enantiomer of r-7, t-8-dihydroxy-7,8-dihydrobenzo(a)pyrene. Proceedings of the National Academy of Sciences ·Shen K. Yang, D W McCourt, Peter P. Roller, Harry V. Gelboin	1976	209
12	Potent Inhibition of Insulin Receptor Dephosphorylation by a Hexamer Peptide Containing the Phosphotyrosyl Mimetic F2Pmp Biochemical and Biophysical Research Communications ·Terrence R. Burke, Hemanta K. Kole, Peter P. Roller	1994	195
13	Rabbit β-Globin Is Extended Beyond Its UGA Stop Codon by Multiple Suppressions and Translational Reading Gaps Biochemistry ·Harold S. Chittum, William S. Lane, Bradley A. Carlson, Peter P. Roller, Feng‐Di T. Lung, Byeong Jae Lee, Dolph L. Hatfield	1998	190
14	The Arf GTPase-activating protein ASAP1 regulates the actin cytoskeleton Proceedings of the National Academy of Sciences ·Paul A. Randazzo, Josefa Andrade, Koichi Miura, Megan T. Brown, Ya‐Qiu Long, Stacey Stauffer, Peter P. Roller, Jonathan A. Cooper	2000	181
15	Thermal stability and conformational transitions of scrapie amyloid (prion) protein correlate with infectivity Protein Science ·Jiri Safar, Peter P. Roller, D. Carleton Gajdusek, Clarence J. Gibbs	1993	176
16	Nonhydrolyzable Phosphotyrosyl Mimetics for the Preparation Of Phosphatase-Resistant SH2 Domain Inhibitors Biochemistry ·Terrence R. Burke, Mark S. Smyth, (unknown), Motoyoshi Nomizu, Peter P. Roller, G. Wolf, Randi D. Case, Steven E. Shoelson	1994	172
17	The GADD45 Inhibition of Cdc2 Kinase Correlates with GADD45-mediated Growth Suppression Journal of Biological Chemistry ·Shunqian Jin, Michael J. Antinore, Feng-Di T. Lung, Xin Dong, Hongcheng Zhao, Feiyue Fan, Amy B. Colchagie, Patricia Blanck, Peter P. Roller, Albert J. Fornace, Qimin Zhan	2000	171
18	Design, Synthesis, and Characterization of a Potent, Nonpeptide, Cell-Permeable, Bivalent Smac Mimetic That Concurrently Targets Both the BIR2 and BIR3 Domains in XIAP Journal of the American Chemical Society ·Haiying Sun, Zaneta Nikolovska‐Coleska, Jianfeng Lü, Jennifer L. Meagher, Chao‐Yie Yang, Su Qiu, York Tomita, Yumi Ueda, Sheng Jiang, Krzysztof Krajewski, Peter P. Roller, Jeanne A. Stuckey, Shaomeng Wang	2007	167
19	Molecular mechanism of gossypol-induced cell growth inhibition and cell death of HT-29 human colon carcinoma cells Biochemical Pharmacology ·Manchao Zhang, Hongpeng Liu, Ribo Guo, Yan Ling, Xiaojin Wu, Bihua Li, Peter P. Roller, Shaomeng Wang, Dajun Yang	2003	161
20	N -Nitrosation by Nitrite Ion in Neutral and Basic Medium Science ·Larry K. Keeper, Peter P. Roller	1973	143

About Peter P. Roller

Peter P. Roller is a scholar working on Molecular Biology, Organic Chemistry, Oncology, Radiology, Nuclear Medicine and Imaging and Biochemistry, having authored 183 papers that have together received 10.4k indexed citations. Recurring topics across this work include Chemical Synthesis and Analysis (35 papers), Protein Kinase Regulation and GTPase Signaling (25 papers), Monoclonal and Polyclonal Antibodies Research (23 papers), Cell death mechanisms and regulation (14 papers), Carbohydrate Chemistry and Synthesis (12 papers), Protein Tyrosine Phosphatases (12 papers), PI3K/AKT/mTOR signaling in cancer (10 papers) and Glycosylation and Glycoproteins Research (9 papers). The work is most often cited by research in Toxicology (360 citations), Molecular Biology (6.8k citations), Immunology and Allergy (474 citations), Organic Chemistry (2.5k citations) and Cancer Research (936 citations). Peter P. Roller has collaborated with scholars based in United States, China and United Kingdom. Frequent co-authors include Shaomeng Wang, Zaneta Nikolovska‐Coleska, Krzysztof Krajewski, Terrence R. Burke, York Tomita, Jeanne A. Stuckey, Jiri Safar, Harry V. Gelboin, Wei Gao and Motoyoshi Nomizu. Their work appears in journals such as Journal of Biological Chemistry, Bioorganic & Medicinal Chemistry Letters, Biochemical and Biophysical Research Communications, Journal of Medicinal Chemistry and Biochemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

Peter P. Roller

Impact in

Papers in i

In The Last Decade

Peter P. Roller

Peter P. Roller's Hit Papers

Peers

Countries citing papers authored by Peter P. Roller

Fields of papers citing papers by Peter P. Roller

All Works

About Peter P. Roller

Explore authors with similar magnitude of impact

Papers in