Peter J. Ratcliffe

78.5k citations
392 papers · 59.3k · 39 hit papers · h-index 105

Impact in

  • Cancer Research top 0.01%
    • Cancer, Hypoxia, and Metabolism
    • Mitochondrial Function and Pathology
    • RNA modifications and cancer
    • Epigenetics and DNA Methylation
    • Angiogenesis and VEGF in Cancer
    • Ubiquitin and proteasome pathways

Papers in

    • Cancer, Hypoxia, and Metabolism 194
    • RNA modifications and cancer 40
    • Epigenetics and DNA Methylation 35
    • Mitochondrial Function and Pathology 33

Peter J. Ratcliffe

377 papers receiving 57.7k citations

Peter J. Ratcliffe's Hit Papers

Conserved N-terminal cysteine dioxygenases transduce responses to hypoxia in animals and plants 2019 · 167 citations
1670+7+14Years since publication50010001.5k2.0k2.5k

Peers

Peter J. Ratcliffe
Comparison fields: 5 of 202
  • Cancer Research 34.8k
  • Molecular Biology 32.2k
  • Biochemistry 2.7k
  • Hematology 3.4k
  • Genetics 8.9k
Replace M. Celeste Simon with:
M. Celeste Simon United States
Patrick H. Maxwell United Kingdom
William G. Kaelin United States
Christopher W. Pugh United Kingdom
Chi V. Dang United States
Gregg L. Semenza United States
Matthew G. Vander Heiden United States
Adrian L. Harris United Kingdom
Tak W. Mak Canada
Douglas R. Green United States
Peter J. Ratcliffe relative to M. Celeste Simon United States M. Celeste Simon's profile →
Citations per field
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M. Celeste Simon · 1×
Citations per year

Countries citing papers authored by Peter J. Ratcliffe

Since Specialization
Citations

This map shows the geographic impact of Peter J. Ratcliffe's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Peter J. Ratcliffe with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Peter J. Ratcliffe more than expected).

Fields of papers citing papers by Peter J. Ratcliffe

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Peter J. Ratcliffe. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Peter J. Ratcliffe. The network helps show where Peter J. Ratcliffe may publish in the future.

Co-authors

The 25 scholars most cited alongside Peter J. Ratcliffe, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Peter J. Ratcliffe Line = papers co-authored together Peter J. Ratcliffe links everyone, so they are left out of the graph.

All Works

20 of 20 papers shown

Showing the 20 most-cited of 392 papers — load more, or switch the sort, to bring in the rest.

#Work
1
Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O 2 -Regulated Prolyl Hydroxylation
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20014714
2
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
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19994342
3
C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation
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20012838
4
Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
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20082566
5
Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
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19982216
6
Regulation of angiogenesis by hypoxia: role of the HIF system
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20032056
7
Oxygen sensing by HIF hydroxylases
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20041707
8
The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages
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20001123
9
Hypoxia-inducible expression of tumor-associated carbonic anhydrases.
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20001113
10
Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth
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1997950
11
Hypoxia Inducible Factor-α Binding and Ubiquitylation by the von Hippel-Lindau Tumor Suppressor Protein
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2000921
12
Differential Function of the Prolyl Hydroxylases PHD1, PHD2, and PHD3 in the Regulation of Hypoxia-inducible Factor
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2004913
13
Independent function of two destruction domains in hypoxia‐inducible factor‐α chains activated by prolyl hydroxylation
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2001883
14
Contrasting Properties of Hypoxia-Inducible Factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-Associated Renal Cell Carcinoma
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2005798
15
The oncometabolite 2‐hydroxyglutarate inhibits histone lysine demethylases
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2011795
16
HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: Novel role of fumarate in regulation of HIF stability
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2005775
17
Structural basis for the recognition of hydroxyproline in HIF-1α by pVHL
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2002634
18
HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors.
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2001626
19
Hypoxia-inducible Factor (HIF) Asparagine Hydroxylase Is Identical to Factor Inhibiting HIF (FIH) and Is Related to the Cupin Structural Family
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2002620
20
Widespread, hypoxia‐inducible expression of HIF‐2α in distinct cell populations of different organs
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2002614

About Peter J. Ratcliffe

Peter J. Ratcliffe is a scholar working on Cancer Research, Molecular Biology, Genetics, Physiology and Hematology, having authored 392 papers that have together received 59.3k indexed citations. Recurring topics across this work include Cancer, Hypoxia, and Metabolism (194 papers), High Altitude and Hypoxia (64 papers), RNA modifications and cancer (40 papers), Epigenetics and DNA Methylation (35 papers), Erythropoietin and Anemia Treatment (34 papers), Adipose Tissue and Metabolism (33 papers), Mitochondrial Function and Pathology (33 papers) and Hemoglobinopathies and Related Disorders (19 papers). The work is most often cited by research in Cancer Research (34.8k citations), Molecular Biology (32.2k citations), Biochemistry (2.7k citations), Hematology (3.4k citations) and Genetics (8.9k citations). Peter J. Ratcliffe has collaborated with scholars based in United Kingdom, United States and Germany. Frequent co-authors include Christopher W. Pugh, Patrick H. Maxwell, Christopher J. Schofield, William G. Kaelin, Adrian L. Harris, David R. Mole, Jonathan Gleadle, Ya‐Min Tian, Charles C. Wykoff and Norma Masson. Their work appears in journals such as Journal of Biological Chemistry, Kidney International, Blood, Proceedings of the National Academy of Sciences and EMBO Reports.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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