Christopher W. Pugh

43.4k citations
147 papers · 32.7k · 20 hit papers · h-index 67

Impact in

  • Cancer Research top 0.01%
    • Cancer, Hypoxia, and Metabolism
    • Mitochondrial Function and Pathology
    • RNA modifications and cancer
    • Epigenetics and DNA Methylation
    • Angiogenesis and VEGF in Cancer
    • Ubiquitin and proteasome pathways

Papers in

    • Cancer, Hypoxia, and Metabolism 89
    • Mitochondrial Function and Pathology 12
    • Epigenetics and DNA Methylation 11
    • RNA modifications and cancer 11
    • Metabolomics and Mass Spectrometry Studies 9

Christopher W. Pugh

144 papers receiving 32.1k citations

Christopher W. Pugh's Hit Papers

High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq 2011 · 568 citations
5680+9+18Years since publication10002.0k3.0k4.0k

Peers

Christopher W. Pugh
Comparison fields: 5 of 178
  • Cancer Research 20.8k
  • Molecular Biology 17.9k
  • Biochemistry 1.6k
  • Genetics 4.9k
  • Physiology 3.8k
Replace Patrick H. Maxwell with:
Patrick H. Maxwell United Kingdom
Jacques Pouysségur France
Chi V. Dang United States
William G. Kaelin United States
M. Celeste Simon United States
Amato J. Giaccia United States
John M. Asara United States
Matthew G. Vander Heiden United States
Richard G. Pestell United States
Roland H. Wenger Switzerland
Christopher W. Pugh relative to Patrick H. Maxwell United Kingdom Patrick H. Maxwell's profile →
Citations per field
00.5×1.5×
Patrick H. Maxwell · 1×
Citations per year

Countries citing papers authored by Christopher W. Pugh

Since Specialization
Citations

This map shows the geographic impact of Christopher W. Pugh's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christopher W. Pugh with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christopher W. Pugh more than expected).

Fields of papers citing papers by Christopher W. Pugh

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christopher W. Pugh. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christopher W. Pugh. The network helps show where Christopher W. Pugh may publish in the future.

Co-authors

The 25 scholars most cited alongside Christopher W. Pugh, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Christopher W. Pugh Line = papers co-authored together Christopher W. Pugh links everyone, so they are left out of the graph.

All Works

20 of 20 papers shown

Showing the 20 most-cited of 147 papers — load more, or switch the sort, to bring in the rest.

#Work
1
Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O 2 -Regulated Prolyl Hydroxylation
Hit paper breakdown →
20014558
2
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
Hit paper breakdown →
19994182
3
C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation
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20012757
4
Regulation of angiogenesis by hypoxia: role of the HIF system
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20031954
5
Hypoxia-inducible expression of tumor-associated carbonic anhydrases.
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20001089
6
The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages
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20001084
7
Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth
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1997919
8
Differential Function of the Prolyl Hydroxylases PHD1, PHD2, and PHD3 in the Regulation of Hypoxia-inducible Factor
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2004893
9
Hypoxia Inducible Factor-α Binding and Ubiquitylation by the von Hippel-Lindau Tumor Suppressor Protein
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2000892
10
Independent function of two destruction domains in hypoxia‐inducible factor‐α chains activated by prolyl hydroxylation
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2001860
11
Contrasting Properties of Hypoxia-Inducible Factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-Associated Renal Cell Carcinoma
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2005765
12
Structural basis for the recognition of hydroxyproline in HIF-1α by pVHL
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2002614
13
Hypoxia-inducible Factor (HIF) Asparagine Hydroxylase Is Identical to Factor Inhibiting HIF (FIH) and Is Related to the Cupin Structural Family
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2002600
14
Widespread, hypoxia‐inducible expression of HIF‐2α in distinct cell populations of different organs
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2002583
15
High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq
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2011568
16
Induction of Endothelial PAS Domain Protein-1 by Hypoxia: Characterization and Comparison With Hypoxia-Inducible Factor-1α
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1998539
17
Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: similarities with the erythropoietin 3' enhancer.
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1994459
18
Activation of Hypoxia-inducible Factor-1; Definition of Regulatory Domains within the α Subunit
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1997434
19
Inducible operation of the erythropoietin 3' enhancer in multiple cell lines: evidence for a widespread oxygen-sensing mechanism.
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1993356
20 2003326

About Christopher W. Pugh

Christopher W. Pugh is a scholar working on Cancer Research, Molecular Biology, Genetics, Surgery and Physiology, having authored 147 papers that have together received 32.7k indexed citations. Recurring topics across this work include Cancer, Hypoxia, and Metabolism (89 papers), High Altitude and Hypoxia (29 papers), Adipose Tissue and Metabolism (17 papers), Erythropoietin and Anemia Treatment (12 papers), Mitochondrial Function and Pathology (12 papers), Epigenetics and DNA Methylation (11 papers), RNA modifications and cancer (11 papers) and Metabolomics and Mass Spectrometry Studies (9 papers). The work is most often cited by research in Cancer Research (20.8k citations), Molecular Biology (17.9k citations), Biochemistry (1.6k citations), Genetics (4.9k citations) and Physiology (3.8k citations). Christopher W. Pugh has collaborated with scholars based in United Kingdom, United States and Germany. Frequent co-authors include Peter J. Ratcliffe, Patrick H. Maxwell, David R. Mole, Ya‐Min Tian, Christopher J. Schofield, Adrian L. Harris, Jonathan Gleadle, Panu Jaakkola, Michael Wilson and Charles C. Wykoff. Their work appears in journals such as Journal of Biological Chemistry, Proceedings of the National Academy of Sciences, Blood, Advances in experimental medicine and biology and The Journal of Physiology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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