Peter D. Smith

1.6k citations

23 papers · 1.4k · 1 hit paper · h-index 15

Impact in

Organic Chemistry top 5%
- Asymmetric Synthesis and Catalysis
- Synthesis and biological activity
- Advanced Synthetic Organic Chemistry
- Click Chemistry and Applications
Pulmonary and Respiratory Medicine top 5%
- Lung Cancer Treatments and Mutations

Papers in

Organic Chemistry 14
- Asymmetric Synthesis and Catalysis 4
- Catalytic C–H Functionalization Methods 4
- Catalytic Cross-Coupling Reactions 3
- Advanced Synthetic Organic Chemistry 2
- Axial and Atropisomeric Chirality Synthesis 1
Cancer Research 3
- Protease and Inhibitor Mechanisms 2
- Cancer, Hypoxia, and Metabolism 1

Co-authors: Patrick D. Bailey (3 shared papers)Michael J. Porter (3 shared papers)Timothy J. Donohoe (3 shared papers)Tom D. Sheppard (4 shared papers)Georgina M. Rosair (2 shared papers)Laure Benhamou (1 shared paper)Dejan‐Krešimir Bučar (1 shared paper)Helen C. Hailes (1 shared paper)
Journals: Journal of Medicinal Chemistry (3 papers)Bioorganic & Medicinal Chemistry Letters (3 papers)Organic Letters (3 papers)The Journal of Organic Chemistry (2 papers)Advanced Synthesis & Catalysis (2 papers)
Partner nations: United Kingdom Sweden United States

In The Last Decade

Peter D. Smith

23 papers receiving 1.3k citations

Peter D. Smith's Hit Papers

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Discovery of a Potent and Selective EGFR Inhibitor (AZD9291) of Both Sensitizing and T790M Resistance Mutations That Spares the Wild Type Form of the Receptor 2014 · 523 citations

What are hit papers?

Paper score: A paper's citations measured against the top-1% bar of its own field and year: the square root of citations ÷ bar, so 1 means right at the bar and 2 means four times its citations. The bar blends the citation counts that enter the top 1% of the paper's subfields in its year (weighted 89.5%), of those subfields over all years (0.5%) and of its year across all fields (10%); a subfield and year with fewer than 400 papers takes its year's bar. Papers from 2026 are not scored yet: in an unfinished year, when a paper appeared matters more than how it is cited.

Hit paper: A paper cited at least 1.5× the top-1% bar of its field and year: a paper score of at least √1.5.

2014 Journal of Medicinal Chemistry

Peers

Countries citing papers authored by Peter D. Smith

Since Specialization

Citations

This map shows the geographic impact of Peter D. Smith's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Peter D. Smith with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Peter D. Smith more than expected).

Fields of papers citing papers by Peter D. Smith

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Peter D. Smith. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Peter D. Smith. The network helps show where Peter D. Smith may publish in the future.

Co-authors

The 25 scholars most cited alongside Peter D. Smith, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Peter D. Smith Line = papers co-authored together Peter D. Smith links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 23 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Discovery of a Potent and Selective EGFR Inhibitor (AZD9291) of Both Sensitizing and T790M Resistance Mutations That Spares the Wild Type Form of the Receptor Journal of Medicinal Chemistry ·M. Raymond V. Finlay, Mark J. Anderton, Susan E. Ashton, Peter G. Ballard, Paul A. Bethel, Matthew R. Box, Robert Hart Bradbury, Simon J. Brown Hit paper breakdown →	2014	523
2	Asymmetric routes to substituted piperidines Chemical Communications ·Patrick D. Bailey, Paula A. Millwood, Peter D. Smith	1998	308
3	Structure- and Reactivity-Based Development of Covalent Inhibitors of the Activating and Gatekeeper Mutant Forms of the Epidermal Growth Factor Receptor (EGFR) Journal of Medicinal Chemistry ·Richard A. Ward, Mark J. Anderton, Susan E. Ashton, Paul A. Bethel, Matthew R. Box, Sam Butterworth, Nicola Colclough, Christopher G. Chorley	2013	234
4	Tetrahydroisoquinoline Phenols: Selective Estrogen Receptor Downregulator Antagonists with Oral Bioavailability in Rat ACS Medicinal Chemistry Letters ·James S. Scott, Robert D. M. Davies, Sébastien L. Degorce, Philip A. MacFaul, H. Gingell, Richard A. Norman, Jennifer H. Pink, Alfred A. Rabow	2015	34
5	Silver-Free Palladium-Catalyzed C(sp3)–H Arylation of Saturated Bicyclic Amine Scaffolds The Journal of Organic Chemistry ·Charlotte E. Coomber, Laure Benhamou, Dejan‐Krešimir Bučar, Peter D. Smith, Michael J. Porter, Tom D. Sheppard	2017	34
6	Catalytic direct amidations in tert -butyl acetate using B(OCH 2 CF 3 ) 3 Organic & Biomolecular Chemistry ·Charlotte E. Coomber, Víctor Laserna, Peter D. Smith, Helen C. Hailes, Michael J. Porter, Tom D. Sheppard +1 other	2019	34
7	Discovery of a Thiadiazole–Pyridazine-Based Allosteric Glutaminase 1 Inhibitor Series That Demonstrates Oral Bioavailability and Activity in Tumor Xenograft Models Journal of Medicinal Chemistry ·M. Raymond V. Finlay, Mark J. Anderton, Scott Boyd, Joanna L. Brookfield, Ceri Cairnduff, Mark D. Charles, Anne Cheasty, Susan E. Critchlow	2019	25
8	Novel 4-anilinoquinazolines with C-6 carbon-linked side chains: Synthesis and structure–activity relationship of a series of potent, orally active, EGF receptor tyrosine kinase inhibitors Bioorganic & Medicinal Chemistry Letters ·Laurent François Hennequin, Peter G. Ballard, F. Tom Boyle, Bénédicte Delouvrié, Rebecca P.A. Ellston, Christopher T. Halsall, Craig Steven Harris, Kevin Hudson	2006	22
9	Catalytic Enolate Arylation with 3-Bromoindoles Allows the Formation of β-Carbolines The Journal of Organic Chemistry ·Peter D. Smith, Timothy J. Donohoe +1 other	2017	20
10	Enantioselective Synthesis of Atropisomeric Biaryls using Biaryl 2,5‐Diphenylphospholanes as Ligands for Palladium‐Catalysed Suzuki‐Miyaura Reactions Advanced Synthesis & Catalysis ·Liam Byrne, Christian Sköld, Per‐Ola Norrby, Rachel H. Munday, Andrew J. Turner, Peter D. Smith	2020	20
11	A high yielding route to substituted piperidines via the aza-Diels–Alder reaction Tetrahedron Letters ·Patrick D. Bailey, Peter D. Smith, Frederick Pederson, W. Clegg, Georgina M. Rosair, Simon J. Teat	2002	18
12	The design and synthesis of novel N-hydroxyformamide inhibitors of ADAM-TS4 for the treatment of osteoarthritis Bioorganic & Medicinal Chemistry Letters ·Chris De Savi, Andrew R. Pape, John G. Cumming, Attilla K. T. Ting, Peter D. Smith, Jeremy Nicholas Burrows, Mark Mills, Chris Davies	2011	18
13	OBO-Protected Pyruvates as Reagents for the Synthesis of Functionalized Heteroaromatic Compounds Organic Letters ·Maria Koyioni, Kirsten E. Christensen, Peter D. Smith, Timothy J. Donohoe +1 other	2018	17
14	Perspectives on the Designation of Oligonucleotide Starting Materials Nucleic Acid Therapeutics ·William F. Kiesman, Andrew K. McPherson, Louis J. Diorazio, Leo Van den Bergh, Peter D. Smith, John M. Northall, Alec Fettes, Tiejun Wang	2021	16
15	Orally active achiral N-hydroxyformamide inhibitors of ADAM-TS4 (aggrecanase-1) and ADAM-TS5 (aggrecanase-2) for the treatment of osteoarthritis Bioorganic & Medicinal Chemistry Letters ·Chris De Savi, Andrew R. Pape, Yvonne Sawyer, David Milne, Chris Davies, John G. Cumming, Attilla K. T. Ting, Scott G. Lamont	2011	15
16	The use of the aza-Diels–Alder reaction in the synthesis of pinidine and other piperidine alkaloids Tetrahedron Letters ·Patrick D. Bailey, Peter D. Smith, Keith M. Morgan, Georgina M. Rosair	2002	12
17	An engineered aldolase enables the biocatalytic synthesis of 2′-functionalized nucleoside analogues Nature Synthesis ·William Finnigan, William R. Birmingham, Sasha R. Derrington, Rachel S. Heath, Christian Schnepel, Martin A. Hayes, Peter D. Smith, Francesco Falcioni	2024	12
18	Pyruvate Enolate Arylation and Alkylation: OBO Ester Protected Pyruvates as Useful Reagents in Organic Synthesis Organic Letters ·Christopher J. J. Hall, Peter D. Smith, Timothy J. Donohoe +1 other	2017	7
19	From Milligram to Kilogram Manufacture of AZD4573: Making It Possible by Application of Enzyme-, Iridium-, and Palladium-Catalyzed Key Transformations Organic Process Research & Development ·Staffan Karlsson, Helen Benson, Calum Cook, Gordon S. Currie, Jérôme Dubiez, Hans Emtenäs, Janet L. Hawkins, Rebecca E. Meadows	2021	7
20	Tuning Reactivity in Pd‐catalysed C( sp 3 )‐H Arylations via Directing Group Modifications and Solvent Selection Advanced Synthesis & Catalysis ·Charlotte E. Coomber, Michael J. Porter, Abil E. Aliev, Peter D. Smith, Tom D. Sheppard	2020	6

About Peter D. Smith

Peter D. Smith is a scholar working on Organic Chemistry, Cancer Research, Inorganic Chemistry, Biochemistry and Molecular Biology, having authored 23 papers that have together received 1.4k indexed citations. Recurring topics across this work include Asymmetric Synthesis and Catalysis (4 papers), Catalytic C–H Functionalization Methods (4 papers), Catalytic Cross-Coupling Reactions (3 papers), Lung Cancer Treatments and Mutations (2 papers), Protease and Inhibitor Mechanisms (2 papers), Advanced Synthetic Organic Chemistry (2 papers), Cancer, Hypoxia, and Metabolism (1 paper) and Axial and Atropisomeric Chirality Synthesis (1 paper). The work is most often cited by research in Organic Chemistry (661 citations), Pulmonary and Respiratory Medicine (415 citations), Computational Theory and Mathematics (110 citations), Cancer Research (58 citations) and Molecular Biology (254 citations). Peter D. Smith has collaborated with scholars based in United Kingdom, Sweden and United States. Frequent co-authors include Patrick D. Bailey, Michael J. Porter, Timothy J. Donohoe, Tom D. Sheppard, Georgina M. Rosair, Laure Benhamou, Dejan‐Krešimir Bučar, Helen C. Hailes, Víctor Laserna and Rachel H. Munday. Their work appears in journals such as Journal of Medicinal Chemistry, Bioorganic & Medicinal Chemistry Letters, Organic Letters, The Journal of Organic Chemistry and Advanced Synthesis & Catalysis.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Peter D. Smith's Hit Papers

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